Phosphonate diester and phosphonamide synthesis. Reaction coordinate analysis by 31P NMR spectroscopy: Identification of pyrophosphonate anhydrides and highly reactive phosphonylammonium salts

Journal of the American Chemical Society

Volumn 119, Issue 35, 1997, Pages 8177-8190

  Hirschmann, Ralph ^a   Yager, Kraig M ^a,b   Taylor, Carol M ^a,c   Witherington, Jason ^a,d   Sprengeler, Paul A ^a,b   Phillips, Barton W ^a   Moore, William ^a   Smith III, Amos B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Arris Pharmaceutical Corporation   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANOPHOSPHORUS COMPOUND; PHOSPHONAMIDE DERIVATIVE; PHOSPHONIC ACID ESTER; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOSPECIFICITY;

EID: 0030818538     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja962465o     Document Type: Article

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