Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

Nature Genetics

Volumn 49, Issue 3, 2017, Pages 367-376

  McDonald, Oliver G ^a   Li, Xin ^b   Saunders, Tyler ^c   Tryggvadottir, Rakel ^b   Mentch, Samantha J ^d   Warmoes, Marc O ^d   Word, Anna E ^a   Carrer, Alessandro ^e   Salz, Tal H ^b   Natsume, Sonoko ^a   Stauffer, Kimberly M ^a   Makohon Moore, Alvin ^c   Zhong, Yi ^c   Wu, Hao ^f   Wellen, Kathryn E ^e   Locasale, Jason W ^d   Iacobuzio Donahue, Christine A ^c   Feinberg, Andrew P ^b  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d DUKE CANCER INSTITUTE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING) B; GLUTAMIC ACID; HISTONE H2AX; HISTONE H3; K RAS PROTEIN; LACTIC ACID; NERVE CELL ADHESION MOLECULE; CHROMATIN; GLUCOSE; HETEROCHROMATIN; HISTONE;

ARTICLE; CANCER GROWTH; CARCINOGENICITY; CONTROLLED STUDY; DISTANT METASTASIS; DNA METHYLATION; EPIGENETICS; EUCHROMATIN; GENE EXPRESSION; GENE MUTATION; GLUCOSE METABOLISM; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LUNG METASTASIS; NUCLEAR REPROGRAMMING; OXIDATIVE STRESS; PANCREAS ADENOCARCINOMA; PENTOSE PHOSPHATE CYCLE; PERITONEUM METASTASIS; PRIMARY TUMOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; RNA INTERFERENCE; TUMOR GROWTH; CARCINOGENESIS; CHROMATIN; GENETIC EPIGENESIS; GENETICS; HETEROCHROMATIN; METABOLISM; METASTASIS; PANCREAS CARCINOMA; PANCREAS TUMOR; PROCEDURES;

CARCINOGENESIS; CARCINOMA, PANCREATIC DUCTAL; CHROMATIN; EPIGENESIS, GENETIC; EPIGENOMICS; GENE EXPRESSION; GLUCOSE; HETEROCHROMATIN; HISTONES; HUMANS; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS;

EID: 85009792040     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3753     Document Type: Article

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