Intracellular IL-37b interacts with Smad3 to suppress multiple signaling pathways and the metastatic phenotype of tumor cells

Oncogene

Volumn 36, Issue 20, 2017, Pages 2889-2899

  Luo, C ^a   Shu, Y ^a   Luo, J ^a   Liu, D ^a   Huang, D S ^b   Han, Y ^b   Chen, C ^c   Li, Y C ^a   Zou, J M ^a   Qin, J ^a   Wang, Y ^a   Li, D ^a   Wang, S S ^a   Zhang, G M ^a   Chen, J ^a   Feng, Z H ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 37; INTERLEUKIN 37B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR PROTEIN; UNCLASSIFIED DRUG; IL37 PROTEIN, HUMAN; INTERLEUKIN 1; PROTEIN BINDING;

95C CELL LINE; 95D CELL LINE; ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER TISSUE; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; HELA CELL LINE; HEP-G2 CELL LINE; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LNCAP CELL LINE; LUNG CANCER CELL LINE; MCF-7 CELL LINE; MDA-MB-231 CELL LINE; METASTATIC CELL LINE; MOUSE; NONHUMAN; PC3 CELL LINE; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAJI CELL LINE; REGULATORY MECHANISM; SK-HEP-1 CELL LINE; TUMOR INVASION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; DISEASE MODEL; GENETICS; INTRACELLULAR SPACE; KAPLAN MEIER METHOD; METABOLISM; METASTASIS; MORTALITY; NEOPLASM; PATHOLOGY; PHOSPHORYLATION; PROGNOSIS; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HETEROGRAFTS; HUMANS; INTERLEUKIN-1; INTRACELLULAR SPACE; KAPLAN-MEIER ESTIMATE; NEOPLASM METASTASIS; NEOPLASMS; NF-KAPPA B; PHENOTYPE; PHOSPHORYLATION; PROGNOSIS; PROTEIN BINDING; SIGNAL TRANSDUCTION; SMAD3 PROTEIN;

EID: 85009740994     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.444     Document Type: Article

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