-
1
-
-
84876871047
-
Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put
-
Simon, J. A. & Kingston, R. E. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol. Cell 49, 808-824 (2013).
-
(2013)
Mol. Cell
, vol.49
, pp. 808-824
-
-
Simon, J.A.1
Kingston, R.E.2
-
2
-
-
65349151439
-
Biochemicalmechanisms of gene regulation by polycomb group protein complexes
-
Mü ller, J. & Verrijzer, P. Biochemicalmechanisms of gene regulation by polycomb group protein complexes. Curr. Opin. Genet. Dev. 19, 150-158 (2009).
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 150-158
-
-
Müller, J.1
Verrijzer, P.2
-
3
-
-
77954758157
-
Polycomb group protein-mediated repression of transcription
-
Morey, L. & Helin, K. Polycomb group protein-mediated repression of transcription. Trends Biochem. Sci. 35, 323-332 (2010).
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 323-332
-
-
Morey, L.1
Helin, K.2
-
4
-
-
70350149728
-
Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice
-
Schuettengruber, B. & Cavalli, G. Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice. Development 136, 3531-3542 (2009).
-
(2009)
Development
, vol.136
, pp. 3531-3542
-
-
Schuettengruber, B.1
Cavalli, G.2
-
5
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch, R. & Young, R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582 (2008).
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
6
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann, A. & van Lohuizen, M. Polycomb silencers control cell fate, development and cancer. Nature Rev. Cancer 6, 846-856 (2006).
-
(2006)
Nature Rev. Cancer
, vol.6
, pp. 846-856
-
-
Sparmann, A.1
Van Lohuizen, M.2
-
7
-
-
33845799903
-
Polycomb silencing mechanisms and the management of genomic programmes
-
Schwartz, Y. B. & Pirrotta, V. Polycomb silencing mechanisms and the management of genomic programmes. Nature Rev. Genet. 8, 9-22 (2007).
-
(2007)
Nature Rev. Genet.
, vol.8
, pp. 9-22
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
8
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron, R. & Reinberg, D. The Polycomb complex PRC2 and its mark in life. Nature 469, 343-349 (2011).
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
9
-
-
18644383738
-
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex
-
Mü ller, J. et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111, 197-208 (2002).
-
(2002)
Cell
, vol.111
, pp. 197-208
-
-
Müller, J.1
-
10
-
-
0037131523
-
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
-
Czermin, B. et al. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111, 185-196 (2002).
-
(2002)
Cell
, vol.111
, pp. 185-196
-
-
Czermin, B.1
-
11
-
-
0036830642
-
Role of histoneH3lysine27methylation inPolycomb-group silencing
-
Cao, R. et al. Role of histoneH3lysine27methylation inPolycomb-group silencing. Science 298, 1039-1043 (2002).
-
(2002)
Science
, vol.298
, pp. 1039-1043
-
-
Cao, R.1
-
12
-
-
0037111831
-
Histonemethyltransferase activity associated with a humanmultiprotein complex containing the Enhancer of Zeste protein
-
Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P. & Reinberg, D. Histonemethyltransferase activity associated with a humanmultiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16, 2893-2905 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2893-2905
-
-
Kuzmichev, A.1
Nishioka, K.2
Erdjument-Bromage, H.3
Tempst, P.4
Reinberg, D.5
-
13
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang, H. et al. Role of histone H2A ubiquitination in Polycomb silencing. Nature 431, 873-878 (2004).
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
-
14
-
-
7744228427
-
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
-
de Napoles, M. et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev. Cell 7, 663-676 (2004).
-
(2004)
Dev. Cell
, vol.7
, pp. 663-676
-
-
De Napoles, M.1
-
15
-
-
9444244427
-
Chromatin compaction by a polycomb group protein complex
-
Francis, N. J., Kingston, R. E. & Woodcock, C. L. Chromatin compaction by a polycomb group protein complex. Science 306, 1574-1577 (2004).
-
(2004)
Science
, vol.306
, pp. 1574-1577
-
-
Francis, N.J.1
Kingston, R.E.2
Woodcock, C.L.3
-
16
-
-
84863011309
-
PCGF homologs CBX proteins and RYBP define functionally distinct PRC1 family complexes
-
Gao, Z. et al. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol. Cell 45, 344-356 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 344-356
-
-
Gao, Z.1
-
17
-
-
84857367297
-
RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3K27me3
-
Tavares, L. et al. RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3K27me3. Cell 148, 664-678 (2012).
-
(2012)
Cell
, vol.148
, pp. 664-678
-
-
Tavares, L.1
-
18
-
-
84873167174
-
RYBP And Cbx7 define specific biological functions of Polycomb complexes in mouse embryonic stem cells
-
Morey, L., Aloia, L., Cozzuto, L., Benitah, S. A. & Di Croce, L. RYBP and Cbx7 define specific biological functions of Polycomb complexes in mouse embryonic stem cells. Cell Rep. 3, 60-69 (2013).
-
(2013)
Cell Rep.
, vol.3
, pp. 60-69
-
-
Morey, L.1
Aloia, L.2
Cozzuto, L.3
Benitah, S.A.4
Di Croce, L.5
-
19
-
-
73749086083
-
Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology
-
Bedogni, F. et al. Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology. Gene Expr. Patterns 10, 9-15 (2010).
-
(2010)
Gene Expr. Patterns
, vol.10
, pp. 9-15
-
-
Bedogni, F.1
-
20
-
-
0036993811
-
Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins
-
Sultana, R. et al. Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins. Genomics 80, 129-134 (2002).
-
(2002)
Genomics
, vol.80
, pp. 129-134
-
-
Sultana, R.1
-
21
-
-
84884416967
-
The role of AUTS2 in neurodevelopment and human evolution
-
Oksenberg, N. & Ahituv, N. The role of AUTS2 in neurodevelopment and human evolution. Trends Genet. 29, 600-608 (2013).
-
(2013)
Trends Genet.
, vol.29
, pp. 600-608
-
-
Oksenberg, N.1
Ahituv, N.2
-
22
-
-
84873732078
-
Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus
-
Beunders, G. et al. Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus. Am. J. Hum. Genet. 92, 210-220 (2013).
-
(2013)
Am. J. Hum. Genet.
, vol.92
, pp. 210-220
-
-
Beunders, G.1
-
23
-
-
84873506311
-
And regulation of AUTS2, a gene implicated in autism and human evolution
-
Oksenberg, N., Stevison, L., Wall, J. D. & Ahituv, N. Function and regulation of AUTS2, a gene implicated in autism and human evolution. PLoS Genet. 9, e1003221 (2013).
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003221
-
-
Oksenberg, N.1
Stevison, L.2
Wall, J.D.3
Function, A.N.4
-
24
-
-
52449086931
-
Unusual repertoire of vocalizations in the BTBR T1tf/J mouse model of autism
-
Scattoni, M. L., Gandhy, S. U., Ricceri, L. & Crawley, J. N. Unusual repertoire of vocalizations in the BTBR T1tf/J mouse model of autism. PLoS ONE 3, e3067 (2008).
-
(2008)
PLoS ONE
, vol.3
, pp. e3067
-
-
Scattoni, M.L.1
Gandhy, S.U.2
Ricceri, L.3
Crawley, J.N.4
-
25
-
-
61849086703
-
Ultrasonic vocalizations: A tool for behavioural phenotyping of mouse models of neurodevelopmental disorders
-
Scattoni, M. L., Crawley, J. & Ricceri, L. Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders. Neurosci. Biobehav. Rev. 33, 508-515 (2009).
-
(2009)
Neurosci. Biobehav. Rev.
, vol.33
, pp. 508-515
-
-
Scattoni, M.L.1
Crawley, J.2
Ricceri, L.3
-
26
-
-
42949179575
-
Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells
-
Fujita, E. et al. Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells. Proc. Natl Acad. Sci. USA 105, 3117-3122 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3117-3122
-
-
Fujita, E.1
-
27
-
-
72449146905
-
Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia
-
Wiame, E. et al. Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia. Biochem. J. 425, 127-136 (2010).
-
(2010)
Biochem. J.
, vol.425
, pp. 127-136
-
-
Wiame, E.1
-
28
-
-
4544337906
-
Follow-up of a child with hypoacetylaspartia
-
Boltshauser, E. et al. Follow-up of a child with hypoacetylaspartia. Neuropediatrics 35, 255-258 (2004).
-
(2004)
Neuropediatrics
, vol.35
, pp. 255-258
-
-
Boltshauser, E.1
-
29
-
-
84865996636
-
Absence ofSHATI/Nat8l reduces social interaction in mice
-
Furukawa-Hibi, Y. et al. Absence ofSHATI/Nat8l reduces social interaction in mice. Neurosci. Lett. 526, 79-84 (2012).
-
(2012)
Neurosci. Lett.
, vol.526
, pp. 79-84
-
-
Furukawa-Hibi, Y.1
-
30
-
-
84892392571
-
Polycomb potentiates Meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer
-
Kondo, T. et al. Polycomb potentiates Meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer. Dev. Cell 28, 94-101 (2014).
-
(2014)
Dev. Cell
, vol.28
, pp. 94-101
-
-
Kondo, T.1
-
31
-
-
84856237597
-
Polycomb protein Ezh1 promotes RNA polymerase II elongation
-
Mousavi, K., Zare, H., Wang, A. H. & Sartorelli, V. Polycomb protein Ezh1 promotes RNA polymerase II elongation. Mol. Cell 45, 255-262 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 255-262
-
-
Mousavi, K.1
Zare, H.2
Wang, A.H.3
Sartorelli, V.4
-
32
-
-
84863012512
-
Direct recruitment of Polycomb repressive complex 1 to chromatin by core binding transcription factors
-
Yu, M. et al. Direct recruitment of Polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol. Cell 45, 330-343 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 330-343
-
-
Yu, M.1
-
33
-
-
84883796667
-
The Aurora B kinase and the Polycomb protein Ring1B combine to regulate active promoters in quiescent lymphocytes
-
Frangini, A. et al. The Aurora B kinase and the Polycomb protein Ring1B combine to regulate active promoters in quiescent lymphocytes. Mol. Cell 51, 647-661 (2013).
-
(2013)
Mol. Cell
, vol.51
, pp. 647-661
-
-
Frangini, A.1
-
34
-
-
77952715009
-
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex
-
Cheung, I. et al. Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc. Natl Acad. Sci. USA 107, 8824-8829 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 8824-8829
-
-
Cheung, I.1
-
35
-
-
84876886897
-
Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood
-
Shulha, H. P., Cheung, I., Guo, Y., Akbarian, S. & Weng, Z. Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. PLoS Genet. 9, e1003433 (2013).
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003433
-
-
Shulha, H.P.1
Cheung, I.2
Guo, Y.3
Akbarian, S.4
Weng, Z.5
-
36
-
-
84874340720
-
Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum
-
James, S. J., Shpyleva, S., Melnyk, S., Pavliv, O. & Pogribny, I. P. Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum. Transl. Psychiatry 3, e232 (2013).
-
(2013)
Transl. Psychiatry
, vol.3
, pp. e232
-
-
James, S.J.1
Shpyleva, S.2
Melnyk, S.3
Pavliv, O.4
Pogribny, I.P.5
-
37
-
-
84905024735
-
Common DNA methylation alterations in multiple brain regions in autism
-
Ladd-Acosta, C. et al. Common DNA methylation alterations in multiple brain regions in autism. Mol. Psychiatry 19, 862-871 (2014).
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 862-871
-
-
Ladd-Acosta, C.1
-
38
-
-
4944245398
-
Human SirT1interacts with histoneH1and promotes formation of facultative heterochromatin
-
Vaquero, A. et al.Human SirT1interacts with histoneH1and promotes formation of facultative heterochromatin. Mol. Cell 16, 93-105 (2004).
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
-
39
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis, S. & Heintz, N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930 (2009).
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
40
-
-
62349130698
-
Ultrafast and memoryefficient alignment of short DNAsequences to the humangenome
-
Langmead, B., Trapnell, C., Pop, M. & Salzberg, S. L. Ultrafast and memoryefficient alignment of short DNAsequences to the humangenome. Genome Biol. 10, R25 (2009).
-
(2009)
Genome Biol.
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
41
-
-
68549104404
-
The Sequence Alignment/Map format and SAMtools
-
Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
-
42
-
-
78651271733
-
Integrative genomics viewer
-
Robinson, J. T. et al. Integrative genomics viewer. Nature Biotechnol. 29, 24-26 (2011).
-
(2011)
Nature Biotechnol.
, vol.29
, pp. 24-26
-
-
Robinson, J.T.1
-
43
-
-
79959349283
-
Genome-wide remodeling of the epigenetic landscape during myogenic differentiation
-
Asp, P. et al. Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. Proc. Natl Acad. Sci. USA 108, E149-E158 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. E149-E158
-
-
Asp, P.1
-
44
-
-
77952214662
-
GREAT improves functional interpretation of cis-regulatory regions
-
McLean, C. Y. et al. GREAT improves functional interpretation of cis-regulatory regions. Nature Biotechnol. 28, 495-501 (2010).
-
(2010)
Nature Biotechnol.
, vol.28
, pp. 495-501
-
-
McLean, C.Y.1
|