메뉴 건너뛰기




Volumn 1, Issue 3, 2016, Pages 131-142

Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation

Author keywords

antithrombotic; atherothrombosis; glycoprotein VI; plaque rupture

Indexed keywords


EID: 85009360423     PISSN: 2452302X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacbts.2016.03.008     Document Type: Review
Times cited : (16)

References (26)
  • 2
    • 84911364795 scopus 로고    scopus 로고
    • Thrombosis formation on atherosclerotic lesions and plaque rupture
    • 2 Badimon, L., Vilahur, G., Thrombosis formation on atherosclerotic lesions and plaque rupture. J Intern Med 276 (2014), 618–632.
    • (2014) J Intern Med , vol.276 , pp. 618-632
    • Badimon, L.1    Vilahur, G.2
  • 3
    • 0028273502 scopus 로고
    • Increased platelet deposition on atherosclerotic coronary arteries
    • 3 van Zanten, G.H., de Graaf, S., Slootweg, P.J., et al. Increased platelet deposition on atherosclerotic coronary arteries. J Clin Invest 93 (1994), 615–632.
    • (1994) J Clin Invest , vol.93 , pp. 615-632
    • van Zanten, G.H.1    de Graaf, S.2    Slootweg, P.J.3
  • 4
    • 20444431568 scopus 로고    scopus 로고
    • Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI
    • 4 Penz, S., Reininger, A.J., Brandl, R., et al. Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. FASEB J 19 (2005), 898–909.
    • (2005) FASEB J , vol.19 , pp. 898-909
    • Penz, S.1    Reininger, A.J.2    Brandl, R.3
  • 5
    • 77649207179 scopus 로고    scopus 로고
    • A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques
    • 5 Reininger, A.J., Bernlochner, I., Penz, S.M., et al. A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. J Am Coll Cardiol 55 (2010), 1147–1158.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1147-1158
    • Reininger, A.J.1    Bernlochner, I.2    Penz, S.M.3
  • 6
    • 46149119865 scopus 로고    scopus 로고
    • Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo
    • 6 Schulz, C., Penz, S., Hoffmann, C., et al. Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo. Basic Res Cardiol 103 (2008), 356–367.
    • (2008) Basic Res Cardiol , vol.103 , pp. 356-367
    • Schulz, C.1    Penz, S.2    Hoffmann, C.3
  • 7
    • 84871094320 scopus 로고    scopus 로고
    • The future of glycoprotein VI as an antithrombotic target
    • 7 Zahid, M., Mangin, P., Loyau, S., et al. The future of glycoprotein VI as an antithrombotic target. J Thromb Haemost 10 (2012), 2418–2427.
    • (2012) J Thromb Haemost , vol.10 , pp. 2418-2427
    • Zahid, M.1    Mangin, P.2    Loyau, S.3
  • 8
    • 84865457895 scopus 로고    scopus 로고
    • Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood
    • 8 Jung, S.M., Moroi, M., Soejima, K., et al. Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood. J Biol Chem 287 (2012), 30000–30013.
    • (2012) J Biol Chem , vol.287 , pp. 30000-30013
    • Jung, S.M.1    Moroi, M.2    Soejima, K.3
  • 9
    • 2242455042 scopus 로고    scopus 로고
    • Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagen
    • 9 Miura, Y., Takahashi, T., Jung, S.M., Moroi, M., Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagen. J Biol Chem 277 (2002), 46197–46204.
    • (2002) J Biol Chem , vol.277 , pp. 46197-46204
    • Miura, Y.1    Takahashi, T.2    Jung, S.M.3    Moroi, M.4
  • 10
    • 67749124481 scopus 로고    scopus 로고
    • Structural insights into the interactions between platelet receptors and fibrillar collagen
    • 10 Herr, A.B., Farndale, R.W., Structural insights into the interactions between platelet receptors and fibrillar collagen. J Biol Chem 284 (2009), 19781–19785.
    • (2009) J Biol Chem , vol.284 , pp. 19781-19785
    • Herr, A.B.1    Farndale, R.W.2
  • 11
    • 9144271618 scopus 로고    scopus 로고
    • Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
    • 11 Smethurst, P.A., Joutsi-Korhonen, L., O'Connor, M.N., et al. Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood 103 (2004), 903–911.
    • (2004) Blood , vol.103 , pp. 903-911
    • Smethurst, P.A.1    Joutsi-Korhonen, L.2    O'Connor, M.N.3
  • 12
    • 1442290149 scopus 로고    scopus 로고
    • Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo
    • 12 Massberg, S., Konrad, I., Bultmann, A., et al. Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. FASEB J 18 (2004), 397–399.
    • (2004) FASEB J , vol.18 , pp. 397-399
    • Massberg, S.1    Konrad, I.2    Bultmann, A.3
  • 13
    • 85027958733 scopus 로고    scopus 로고
    • Novel antiplatelet drug revacept (dimeric glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans
    • 13 Ungerer, M., Rosport, K., Bultmann, A., et al. Novel antiplatelet drug revacept (dimeric glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans. Circulation 123 (2011), 1891–1899.
    • (2011) Circulation , vol.123 , pp. 1891-1899
    • Ungerer, M.1    Rosport, K.2    Bultmann, A.3
  • 14
    • 84867888747 scopus 로고    scopus 로고
    • Platelet GPVI: a target for antithrombotic therapy?!
    • 14 Dutting, S., Bender, M., Nieswandt, B., Platelet GPVI: a target for antithrombotic therapy?!. Trends Pharmacol Sci 33 (2012), 583–590.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 583-590
    • Dutting, S.1    Bender, M.2    Nieswandt, B.3
  • 15
    • 84867144287 scopus 로고    scopus 로고
    • Inhibitors of the interactions between collagen and its receptors on platelets
    • 15 Deckmyn, H., De Meyer, S.F., Broos, K., Vanhoorelbeke, K., Inhibitors of the interactions between collagen and its receptors on platelets. Handb Exp Pharmacol(210), 2012, 311–337.
    • (2012) Handb Exp Pharmacol , Issue.210 , pp. 311-337
    • Deckmyn, H.1    De Meyer, S.F.2    Broos, K.3    Vanhoorelbeke, K.4
  • 16
    • 84930885500 scopus 로고    scopus 로고
    • Differential inhibition of human atherosclerotic plaque-induced platelet activation by dimeric GPVI-Fc and anti-GPVI antibodies: Functional and imaging studies
    • 16 Jamasbi, J., Megens, R.T., Bianchini, M., et al. Differential inhibition of human atherosclerotic plaque-induced platelet activation by dimeric GPVI-Fc and anti-GPVI antibodies: Functional and imaging studies. J Am Coll Cardiol 65 (2015), 2404–2415.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 2404-2415
    • Jamasbi, J.1    Megens, R.T.2    Bianchini, M.3
  • 17
    • 0030778796 scopus 로고    scopus 로고
    • Topographic analysis of proliferative activity in carotid endarterectomy specimens by immunocytochemical detection of the cell cycle-related antigen Ki-67
    • 17 Brandl, R., Richter, T., Haug, K., Wilhelm, M.G., Maurer, P.C., Nathrath, W., Topographic analysis of proliferative activity in carotid endarterectomy specimens by immunocytochemical detection of the cell cycle-related antigen Ki-67. Circulation 96 (1997), 3360–3368.
    • (1997) Circulation , vol.96 , pp. 3360-3368
    • Brandl, R.1    Richter, T.2    Haug, K.3    Wilhelm, M.G.4    Maurer, P.C.5    Nathrath, W.6
  • 18
    • 84865224181 scopus 로고    scopus 로고
    • Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry
    • 18 Bampalis, V.G., Brantl, S.A., Siess, W., Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry. J Thromb Haemost 10 (2012), 1710–1714.
    • (2012) J Thromb Haemost , vol.10 , pp. 1710-1714
    • Bampalis, V.G.1    Brantl, S.A.2    Siess, W.3
  • 19
    • 78649686720 scopus 로고    scopus 로고
    • Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
    • 19 Dwivedi, S., Pandey, D., Khandoga, A.L., Brandl, R., Siess, W., Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque. J Transl Med, 8, 2010, 128.
    • (2010) J Transl Med , vol.8 , pp. 128
    • Dwivedi, S.1    Pandey, D.2    Khandoga, A.L.3    Brandl, R.4    Siess, W.5
  • 20
    • 84890093005 scopus 로고    scopus 로고
    • Incisive imaging and computation for cellular mysteries: lessons from abscission
    • 20 Elia, N., Ott, C., Lippincott-Schwartz, J., Incisive imaging and computation for cellular mysteries: lessons from abscission. Cell 155 (2013), 1220–1231.
    • (2013) Cell , vol.155 , pp. 1220-1231
    • Elia, N.1    Ott, C.2    Lippincott-Schwartz, J.3
  • 21
    • 34548162559 scopus 로고    scopus 로고
    • Frequency and distribution of thin-cap fibroatheroma and ruptured plaques in human coronary arteries: a pathologic study
    • 21 Cheruvu, P.K., Finn, A.V., Gardner, C., et al. Frequency and distribution of thin-cap fibroatheroma and ruptured plaques in human coronary arteries: a pathologic study. J Am Coll Cardiol 50 (2007), 940–949.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 940-949
    • Cheruvu, P.K.1    Finn, A.V.2    Gardner, C.3
  • 22
    • 58149401290 scopus 로고    scopus 로고
    • Two-photon microscopy on vital carotid arteries: imaging the relationship between collagen and inflammatory cells in atherosclerotic plaques
    • 22 Megens, R.T., oude Egbrink, M.G., Merkx, M., Slaaf, D.W., van Zandvoort, M.A., Two-photon microscopy on vital carotid arteries: imaging the relationship between collagen and inflammatory cells in atherosclerotic plaques. J Biomed Opt, 13, 2008, 044022.
    • (2008) J Biomed Opt , vol.13 , pp. 044022
    • Megens, R.T.1    oude Egbrink, M.G.2    Merkx, M.3    Slaaf, D.W.4    van Zandvoort, M.A.5
  • 25
    • 34948848572 scopus 로고    scopus 로고
    • Platelet glycoprotein VI-related clinical defects
    • 25 Arthur, J.F., Dunkley, S., Andrews, R.K., Platelet glycoprotein VI-related clinical defects. Br J Haematol 139 (2007), 363–372.
    • (2007) Br J Haematol , vol.139 , pp. 363-372
    • Arthur, J.F.1    Dunkley, S.2    Andrews, R.K.3
  • 26
    • 50249135564 scopus 로고    scopus 로고
    • Multivalency: the hallmark of antibodies used for optimization of tumor targeting by design
    • 26 Deyev, S.M., Lebedenko, E.N., Multivalency: the hallmark of antibodies used for optimization of tumor targeting by design. Bioessays 30 (2008), 904–918.
    • (2008) Bioessays , vol.30 , pp. 904-918
    • Deyev, S.M.1    Lebedenko, E.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.