Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 8, 2012, Pages 1710-1714

  Bampalis, V G ^a   Brantl, S A ^a   Siess, W ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; HIRUDIN;

ANTICOAGULATION; BLOOD ANALYSIS; BLOOD SAMPLING; CENTRIFUGATION; ERYTHROCYTE; HEMODILUTION; HUMAN; INCUBATION TIME; LETTER; MULTIPLE ELECTRODE AGGREGOMETRY; PRIORITY JOURNAL; SPONTANEOUS PLATELET AGGREGATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT;

ADENOSINE DIPHOSPHATE; ELECTRODES; ERYTHROCYTES; HUMANS; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; THROMBOSIS;

EID: 84865224181     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04819.x     Document Type: Letter

References (37)

1. Suehiro A, Uedaa M, Suehiroh M, Ohe Y, Kakishitaa E. Evaluation of platelet hyperfunction in aged subjects using spontaneous platelet aggregation in whole blood. Arch Gerontol Geriatr 1995; 21: 277-83.
2. Gray RP, Hendra TJ, Patterson DL, Yudkin JS. 'Spontaneous' platelet aggregation in whole blood in diabetic and non diabetic survivors of acute myocardial infarction. Thromb Haemost 1993; 70: 932-6.
3. Krause S, May J, Koslowski H, Heptinstall S, Losche W. Enhanced spontaneous platelet aggregation and red blood cell fragility in whole blood obtained from patients with diabetes. Platelets 1991; 2: 203-6.
4. Casonato A, De Marco L, Mazzucato M, De Angelis V, De Roia D, Fabris F, Ruggeri ZM, Girolami A. A new congenital platelet abnormality characterized by spontaneous platelet aggregation, enhanced von Willebrand factor platelet interaction, and the presence of all von Willebrand factor multimers in plasma. Blood 1989; 74: 2028-33.
5. Hendra TJ, Yudkin JS. 'Spontaneous' platelet aggregation in whole blood in diabetic patients with and without microvascular disease. Diabet Med 1992; 9: 247-51.
6. Eto K, Takeshita S, Ochiai M, Ozaki Y, Sato T, Isshiki T. Platelet aggregation in acute coronary syndromes: use of a new aggregometer with laser light scattering to assess platelet aggregability. Cardiovasc Res 1998; 40: 223-9.
7. Hoogendijk EM, Jenkins CS, van Wijk EM, Vos J, ten Cate JW. Spontaneous platelet aggregation in cerebrovascular disease II. Further characterisation of the platelet defect. Thromb Haemost 1979; 41: 512-22.
8. Komarnicki M, Kazmierczak M, Haertle D. Standard heparin and low molecular weight heparin effect on spontaneous platelet aggregation measured in whole blood and in platelet-rich plasma. Acta Haematol Pol 1993; 24: 263-5.
9. Gabbianelli R, Falcioni G, Dow CS, Vince FP, Swoboda B. A new method to evaluate spontaneous platelet aggregation in type 2 diabetes by Cellfacts. Clin Chim Acta 2003; 329: 95-102.
10. Lecrubier C, Conard J, Horellou MH, Kher A, Samama M. Spontaneous platelet aggregation in heparin-treated patients. Acta Haematol 1984; 71: 63-5.
11. Fox SC, Kilby MD, Sanderson HM, Heptinstall S. Investigations on spontaneous aggregation and platelet responses to streptokinase and to adrenaline during pregnancy. Platelets 1994; 5: 139-44.
12. Paulsen EP, McClung NM, Sabio H. Some characteristics of spontaneous platelet aggregation in young insulin-dependent diabetic subjects. Horm Metab Res Suppl 1981; 11: 15-21.
13. Iwase E, Tawata M, Aida K, Ozaki Y, Kume S, Satoh K, Qi R, Onaya T. A cross-sectional evaluation of spontaneous platelet aggregation in relation to complications in patients with type II diabetes mellitus. Metabolism 1998; 47: 699-705.
14. Trip MD, Cats VM, van Capelle FJ, Vreeken J. Platelet hyperreactivity and prognosis in survivors of myocardial infarction. N Engl J Med 1990; 322: 1549-54.
15. Breddin HK, Lippold R, Bittner M, Kirchmaier CM, Krzywanek HJ, Michaelis J. Spontaneous platelet aggregation as a predictive risk factor for vascular occlusions in healthy volunteers? Results of the HAPARG Study. Haemostatic parameters as risk factors in healthy volunteers. Atherosclerosis 1999; 144: 211-9.
16. Gaarder A, Jonsen J, Laland S, Hellem A, Owren PA. Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets. Nature 1961; 192: 531-2.
17. Aursnes I, Gjesdal K, Abildgaard U. Platelet aggregation induced by ADP from unsheared erythrocytes at physiological Ca++-concentration. Br J Haematol 1981; 47: 149-52.
18. Saniabadi AR, Lowe GD, Barbenel JC, Forbes CD. A comparison of spontaneous platelet aggregation in whole blood with platelet rich plasma: additional evidence for the role of ADP. Thromb Haemost 1984; 51: 115-8.
19. Saniabadi AR, Lowe GD, Barbenel JC, Forbes CD. Further studies on the role of red blood cells in spontaneous platelet aggregation. Thromb Res 1985; 38: 225-32.
20. Brown P, Harrison MJ. The role of red blood cells in platelet aggregation in whole blood. Atherosclerosis 1988; 71: 261-2.
21. May J, Loesche W, Heptinstall S. Glucose increases spontaneous platelet aggregation in whole blood. Thromb Res 1990; 59: 489-95.
22. Born GV, Bergquist D, Arfors KE. Evidence for inhibition of platelet activation in blood by a drug effect on erythrocytes. Nature 1976; 259: 233-5.
23. Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 1996; 143: 1-13.
24. Halkes PH, van Gijn J, Kappelle LJ, Koudstaal PJ, Algra A. Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet 2006; 367: 1665-73.
25. Gresele P, Arnout J, Deckmyn H, Vermylen J. Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity. Thromb Haemost 1986; 55: 12-8.
26. Saniabadi AR, Lowe GD, Barbenel JC, Forbes CD. Effect of dipyridamole on spontaneous platelet aggregation in whole blood decreases with the time after venepuncture: evidence for the role of ADP. Thromb Haemost 1987; 58: 744-8.
27. Harrison MJ, Pollock SS, Steiner M, Weisblatt E. Inhibitors of 'spontaneous' platelet aggregation in whole blood. Atherosclerosis 1985; 58: 199-203.
28. Toth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006; 96: 781-8.
29. Elalamy I, Galea V, Hatmi M, Gerotziafas GT. Heparin-induced multiple electrode aggregometry: a potential tool for improvement of heparin-induced thrombocytopenia diagnosis. J Thromb Haemost 2009; 7: 1932-4.
30. Siller-Matula JM, Christ G, Lang IM, Delle-Karth G, Huber K, Jilma B. Multiple electrode aggregometry predicts stent thrombosis better than the vasodilator-stimulated phosphoprotein phosphorylation assay. J Thromb Haemost 2010; 8: 351-9.
31. Multiplate in the literature. Version 21.0. http://www.multiplate.net/; 25 August 2011.
32. Hu H, Hoylaerts MF. The P2X1 ion channel in platelet function. Platelets 2010; 21: 153-66.
33. Gachet C. Regulation of platelet functions by P2 receptors. Annu Rev Pharmacol Toxicol 2006; 46: 277-300.
34. Sprague RS, Ellsworth ML, Stephenson AH, Lonigro AJ. ATP: the red blood cell link to NO and local control of the pulmonary circulation. Am J Physiol 1996; 271: H2717-22.
35. Rozier MD, Zata VJ, Ellsworth ML. Lactate interferes with ATP release from red blood cells. Am J Physiol Heart Circ Physiol 2007; 292: H3038-42.
36. Dean BM, Perrett D. Studies on adenine and adenosine metabolism by intact human erythrocytes using high performance liquid chromatography. Biochim Biophys Acta 1976; 437: 1-5.
37. Dwivedi S, Pandey D, Khandoga AL, Brandl R, Siess W. Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque. J Transl Med 2010; 8: 128.