-
1
-
-
0036851876
-
Platelets in atherothrombosis
-
DOI 10.1038/nm1102-1227
-
Ruggeri ZM. Platelets in atherothrombosis. Nat Med. 2002;8:1227-1234. (Pubitemid 35373553)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1227-1234
-
-
Ruggeri, Z.M.1
-
2
-
-
0037118664
-
Platelet glycoprotein IIb/IIIa inhibitors: Recognition of a two-edged sword?
-
DOI 10.1161/01.CIR.0000019581.22812.B2
-
Quinn MJ, Plow EF, Topol EJ. Platelet glycoprotein IIb/IIIa inhibitors: recognition of a two-edged sword? Circulation. 2002;106:379-385. (Pubitemid 34778965)
-
(2002)
Circulation
, vol.106
, Issue.3
, pp. 379-385
-
-
Quinn, M.J.1
Plow, E.F.2
Topol, E.J.3
-
3
-
-
74549203360
-
Balancing benefit and bleeding risk of antithrombotic agents in the individual patient with an acute coronary syndrome
-
Van de Werf F. Balancing benefit and bleeding risk of antithrombotic agents in the individual patient with an acute coronary syndrome. Circulation. 2010;121:5-7.
-
(2010)
Circulation
, vol.121
, pp. 5-7
-
-
Van De Werf, F.1
-
4
-
-
74449093103
-
Prognostic modeling of individual patient risk and mortality impact of ischemic and hemorrhagic complications: Assessment from the Acute Catheterization and Urgent Intervention Triage Strategy trial
-
Pocock SJ, Mehran R, Clayton TC, Nikolsky E, Parise H, Fahy M, Lansky AJ, Bertrand ME, Lincoff AM, Moses JW, Ohman EM, White HD, Stone GW. Prognostic modeling of individual patient risk and mortality impact of ischemic and hemorrhagic complications: assessment from the Acute Catheterization and Urgent Intervention Triage Strategy trial. Circulation. 2010;121:43-51.
-
(2010)
Circulation
, vol.121
, pp. 43-51
-
-
Pocock, S.J.1
Mehran, R.2
Clayton, T.C.3
Nikolsky, E.4
Parise, H.5
Fahy, M.6
Lansky, A.J.7
Bertrand, M.E.8
Lincoff, A.M.9
Moses, J.W.10
Ohman, E.M.11
White, H.D.12
Stone, G.W.13
-
5
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
DOI 10.1056/NEJMoa0706482
-
Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, Neumann FJ, Ardissino D, De SS, Murphy SA, Riesmeyer J, Weerakkody G, Gibson CM, Antman EM. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357: 2001-2015. (Pubitemid 350106708)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.20
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Montalescot, G.4
Ruzyllo, W.5
Gottlieb, S.6
Neumann, F.-J.7
Ardissino, D.8
De Servi, S.9
Murphy, S.A.10
Riesmeyer, J.11
Weerakkody, G.12
Gibson, C.M.13
Antman, E.M.14
-
6
-
-
1442290149
-
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo
-
Massberg S, Konrad I, Bultmann A, Schulz C, Munch G, Peluso M, Lorenz M, Schneider S, Besta F, Muller I, Hu B, Langer H, Kremmer E, Rudelius M, Heinzmann U, Ungerer M, Gawaz M. Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. FASEB J. 2004;18:397-399.
-
(2004)
FASEB J
, vol.18
, pp. 397-399
-
-
Massberg, S.1
Konrad, I.2
Bultmann, A.3
Schulz, C.4
Munch, G.5
Peluso, M.6
Lorenz, M.7
Schneider, S.8
Besta, F.9
Muller, I.10
Hu, B.11
Langer, H.12
Kremmer, E.13
Rudelius, M.14
Heinzmann, U.15
Ungerer, M.16
Gawaz, M.17
-
7
-
-
0038494921
-
Platelet-collagen interaction: Is GPVI the central receptor?
-
DOI 10.1182/blood-2002-12-3882
-
Nieswandt B, Watson SP. Platelet-collagen interaction: is GPVI the central receptor? Blood. 2003;102:449-461. (Pubitemid 36841960)
-
(2003)
Blood
, vol.102
, Issue.2
, pp. 449-461
-
-
Nieswandt, B.1
Watson, S.P.2
-
8
-
-
46149119865
-
Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo
-
Schulz C, Penz S, Hoffmann C, Langer H, Gillitzer A, Schneider S, Brandl R, Seidl S, Massberg S, Pichler B, Kremmer E, Stellos K, Schonberger T, Siess W, Gawaz M. Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo. Basic Res Cardiol. 2008; 103:356-367.
-
(2008)
Basic Res Cardiol
, vol.103
, pp. 356-367
-
-
Schulz, C.1
Penz, S.2
Hoffmann, C.3
Langer, H.4
Gillitzer, A.5
Schneider, S.6
Brandl, R.7
Seidl, S.8
Massberg, S.9
Pichler, B.10
Kremmer, E.11
Stellos, K.12
Schonberger, T.13
Siess, W.14
Gawaz, M.15
-
9
-
-
20444431568
-
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI
-
DOI 10.1096/fj.04-2748com
-
Penz S, Reininger AJ, Brandl R, Goyal P, Rabie T, Bernlochner I, Rother E, Goetz C, Engelmann B, Smethurst PA, Ouwehand WH, Farndale R, Nieswandt B, Siess W. Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. FASEB J. 2005;19: 898-909. (Pubitemid 40827712)
-
(2005)
FASEB Journal
, vol.19
, Issue.8
, pp. 898-909
-
-
Penz, S.1
Reininger, A.J.2
Brandl, R.3
Goyal, P.4
Rabie, T.5
Bernlochner, I.6
Rother, E.7
Goetz, C.8
Engelmann, B.9
Smethurst, P.A.10
Ouwehand, W.H.11
Farndale, R.12
Nieswandt, B.13
Siess, W.14
-
10
-
-
77649207179
-
A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques
-
Reininger AJ, Bernlochner I, Penz SM, Ravanat C, Smethurst P, Farndale RW, Gachet C, Brandl R, Siess W. A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. J Am Coll Cardiol. 2010;55:1147-1158.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1147-1158
-
-
Reininger, A.J.1
Bernlochner, I.2
Penz, S.M.3
Ravanat, C.4
Smethurst, P.5
Farndale, R.W.6
Gachet, C.7
Brandl, R.8
Siess, W.9
-
11
-
-
13544270777
-
Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice
-
DOI 10.1182/blood-2004-06-2391
-
Gruner S, Prostredna M, Koch M, Miura Y, Schulte V, Jung SM, Moroi M, Nieswandt B. Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice. Blood. 2005;105: 1492-1499. (Pubitemid 40223665)
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1492-1499
-
-
Gruner, S.1
Prostredna, M.2
Koch, M.3
Miura, Y.4
Schulte, V.5
Jung, S.M.6
Moroi, M.7
Nieswandt, B.8
-
12
-
-
0035862627
-
Differential antiplatelet effects of various glycoprotein IIb-IIIa antagonists
-
DOI 10.1016/S0049-3848(00)00385-6, PII S0049384800003856
-
Dickfeld T, Ruf A, Pogatsa-Murray G, Muller I, Engelmann B, Taubitz W, Fischer J, Meier O, Gawaz M. Differential antiplatelet effects of various glycoprotein IIb-IIIa antagonists. Thromb Res. 2001; 101:53-64. (Pubitemid 32141179)
-
(2001)
Thrombosis Research
, vol.101
, Issue.2
, pp. 53-64
-
-
Dickfeld, T.1
Ruf, A.2
Pogatsa-Murray, G.3
Muller, I.4
Engelmann, B.5
Taubitz, W.6
Fischer, J.7
Meier, O.8
Gawaz, M.9
-
13
-
-
4944261759
-
Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy
-
DOI 10.1161/01.CIR.0000137972.74120.12
-
Kastrati A, von BN, Joost A, Pogatsa-Murray G, Gorchakova O, Schomig A. Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy. Circulation. 2004; 110:1916-1919. (Pubitemid 39331901)
-
(2004)
Circulation
, vol.110
, Issue.14
, pp. 1916-1919
-
-
Kastrati, A.1
Von Beckerath, N.2
Joost, A.3
Pogatsa-Murray, G.4
Gorchakova, O.5
Schomig, A.6
-
14
-
-
44249122195
-
Bivalirudin during primary PCI in acute myocardial infarction
-
DOI 10.1056/NEJMoa0708191
-
Stone GW, Witzenbichler B, Guagliumi G, Peruga JZ, Brodie BR, Dudek D, Kornowski R, Hartmann F, Gersh BJ, Pocock SJ, Dangas G, Wong SC, Kirtane AJ, Parise H, Mehran R. Bivalirudin during primary PCI in acute myocardial infarction. N Engl J Med. 2008;358: 2218-2230. (Pubitemid 351724451)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.21
, pp. 2218-2230
-
-
Stone, G.W.1
Witzenbichler, B.2
Guagliumi, G.3
Peruga, J.Z.4
Brodie, B.R.5
Dudek, D.6
Kornowski, R.7
Hartmann, F.8
Gersh, B.J.9
Pocock, S.J.10
Dangas, G.11
Wong, S.C.12
Kirtane, A.J.13
Parise, H.14
Mehran, R.15
-
15
-
-
38949179203
-
Periprocedural Bleeding and 1-Year Outcome After Percutaneous Coronary Interventions. Appropriateness of Including Bleeding as a Component of a Quadruple End Point
-
DOI 10.1016/j.jacc.2007.10.040, PII S073510970703745X
-
Ndrepepa G, Berger PB, Mehilli J, Seyfarth M, Neumann FJ, Schomig A, Kastrati A. Periprocedural bleeding and 1-year outcome after percutaneous coronary interventions: appropriateness of including bleeding as a component of a quadruple end point. J Am Coll Cardiol. 2008;51: 690-697. (Pubitemid 351221218)
-
(2008)
Journal of the American College of Cardiology
, vol.51
, Issue.7
, pp. 690-697
-
-
Ndrepepa, G.1
Berger, P.B.2
Mehilli, J.3
Seyfarth, M.4
Neumann, F.-J.5
Schomig, A.6
Kastrati, A.7
-
16
-
-
77955276576
-
Impact of glycoprotein VI and platelet adhesion on atherosclerosis: A possible role of fibronectin
-
Bültmann A, Li Z, Wagner S, Peluso M, Schönberger T, Weis C, Konrad I, Stellos K, Massberg S, Nieswandt B, Gawaz M, Ungerer M, Münch G. Impact of glycoprotein VI and platelet adhesion on atherosclerosis: a possible role of fibronectin. J Mol Cell Cardiol. 2010;49: 532-542.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 532-542
-
-
Bültmann, A.1
Li, Z.2
Wagner, S.3
Peluso, M.4
Schönberger, T.5
Weis, C.6
Konrad, I.7
Stellos, K.8
Massberg, S.9
Nieswandt, B.10
Gawaz, M.11
Ungerer, M.12
Münch, G.13
-
17
-
-
77951537668
-
Platelet glycoprotein VI (GPVI) for early identification of acute coronary syndrome in patients with chest pain
-
Bigalke B, Haap M, Stellos K, Geisler T, Seizer P, Kremmer E, Overkamp D, Gawaz M. Platelet glycoprotein VI (GPVI) for early identification of acute coronary syndrome in patients with chest pain. Thromb Res. 2010;125:e184-e189.
-
(2010)
Thromb Res
, vol.125
-
-
Bigalke, B.1
Haap, M.2
Stellos, K.3
Geisler, T.4
Seizer, P.5
Kremmer, E.6
Overkamp, D.7
Gawaz, M.8
-
18
-
-
45849149636
-
Platelet collagen receptor glycoprotein VI as a possible novel indicator for the acute coronary syndrome
-
Bigalke B, Geisler T, Stellos K, Langer H, Daub K, Kremmer E, Seizer P, May AE, Lindemann S, Gawaz M. Platelet collagen receptor glycoprotein VI as a possible novel indicator for the acute coronary syndrome. Am Heart J. 2008;156:193-200.
-
(2008)
Am Heart J
, vol.156
, pp. 193-200
-
-
Bigalke, B.1
Geisler, T.2
Stellos, K.3
Langer, H.4
Daub, K.5
Kremmer, E.6
Seizer, P.7
May, A.E.8
Lindemann, S.9
Gawaz, M.10
-
19
-
-
73449086712
-
Expression of platelet glycoprotein VI is associated with transient ischemic attack and stroke
-
Bigalke B, Stellos K, Geisler T, Kremmer E, Seizer P, May AE, Lindemann S, Melms A, Luft A, Gawaz M. Expression of platelet glycoprotein VI is associated with transient ischemic attack and stroke. Eur J Neurol. 2010;17:111-117.
-
(2010)
Eur J Neurol
, vol.17
, pp. 111-117
-
-
Bigalke, B.1
Stellos, K.2
Geisler, T.3
Kremmer, E.4
Seizer, P.5
May, A.E.6
Lindemann, S.7
Melms, A.8
Luft, A.9
Gawaz, M.10
-
20
-
-
67349237179
-
Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS)
-
Bigalke B, Stellos K, Weig HJ, Geisler T, Seizer P, Kremmer E, Potz O, Joos T, May AE, Lindemann S, Gawaz M. Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS). Basic Res Cardiol. 2009;104:352-357.
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 352-357
-
-
Bigalke, B.1
Stellos, K.2
Weig, H.J.3
Geisler, T.4
Seizer, P.5
Kremmer, E.6
Potz, O.7
Joos, T.8
May, A.E.9
Lindemann, S.10
Gawaz, M.11
-
21
-
-
0037240588
-
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo
-
DOI 10.1084/jem.20020945
-
Massberg S, Gawaz M, Gruner S, Schulte V, Konrad I, Zohlnhofer D, Heinzmann U, Nieswandt B. A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. J Exp Med. 2003;197: 41-49. (Pubitemid 36110256)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.1
, pp. 41-49
-
-
Massberg, S.1
Gawaz, M.2
Gruner, S.3
Schulte, V.4
Konrad, I.5
Zohlnhofer, D.6
Heinzmann, U.7
Nieswandt, B.8
-
22
-
-
0035910757
-
Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice
-
DOI 10.1084/jem.193.4.459
-
Nieswandt B, Schulte V, Bergmeier W, Mokhtari-Nejad R, Rackebrandt K, Cazenave JP, Ohlmann P, Gachet C, Zirngibl H. Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice. J Exp Med. 2001;193:459-469. (Pubitemid 32524477)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.4
, pp. 459-469
-
-
Nieswandt, B.1
Schulte, V.2
Bergmeier, W.3
Mokhtari-Nejad, R.4
Rackebrandt, K.5
Cazenave, J.-P.6
Ohlmann, P.7
Gachet, C.8
Zirngibl, H.9
-
23
-
-
4444244926
-
Anti-GPVI-associated ITP: An acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRγ-chain complex from the human platelet surface
-
DOI 10.1182/blood-2004-03-0896
-
Boylan B, Chen H, Rathore V, Paddock C, Salacz M, Friedman KD, Curtis BR, Stapleton M, Newman DK, Kahn ML, Newman PJ. Anti- GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. Blood. 2004;104: 1350-1355. (Pubitemid 39166510)
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1350-1355
-
-
Boylan, B.1
Chen, H.2
Rathore, V.3
Paddock, C.4
Salacz, M.5
Friedman, K.D.6
Curtis, B.R.7
Stapleton, M.8
Newman, D.K.9
Kahn, M.L.10
Newman, P.J.11
-
24
-
-
0024426540
-
A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion
-
Moroi M, Jung SM, Okuma M, Shinmyozu K. A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion. J Clin Invest. 1989;84:1440-1445. (Pubitemid 19272230)
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.5
, pp. 1440-1445
-
-
Moroi, M.1
Jung, S.M.2
Okuma, M.3
Shinmyozu, K.4
-
25
-
-
43749099001
-
Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression
-
DOI 10.1111/j.1538-7836.2008.02976.x
-
Ohlmann P, Hechler B, Ravanat C, Loyau S, Herrenschmidt N, Wanert F, Jandrot-Perrus M, Gachet C. Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression. J Thromb Haemost. 2008;6: 1003-1011. (Pubitemid 351689923)
-
(2008)
Journal of Thrombosis and Haemostasis
, vol.6
, Issue.6
, pp. 1003-1011
-
-
Ohlmann, P.1
Hechler, B.2
Ravanat, C.3
Loyau, S.4
Herrenschmidt, N.5
Wanert, F.6
Jandrot-Perrus, M.7
Gachet, C.8
-
26
-
-
34247398257
-
The fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats
-
DOI 10.1161/ATVBAHA.107.140590
-
Li H, Lockyer S, Concepcion A, Gong X, Takizawa H, Guertin M, Matsumoto Y, Kambayashi J, Tandon NN, Liu Y. The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats. Arterioscler Thromb Vasc Biol. 2007;27: 1199-1205. (Pubitemid 46641979)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.5
, pp. 1199-1205
-
-
Li, H.1
Lockyer, S.2
Concepcion, A.3
Gong, X.4
Takizawa, H.5
Guertin, M.6
Matsumoto, Y.7
Kambayashi, J.8
Tandon, N.N.9
Liu, Y.10
-
27
-
-
8144222110
-
1 levels or concomitant aspirin therapy
-
DOI 10.1161/01.CIR.0000146341.63677.3C
-
Gruner S, Prostredna M, Aktas B, Moers A, Schulte V, Krieg T, Offermanns S, Eckes B, Nieswandt B. Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy. Circulation. 2004;110: 2946-2951. (Pubitemid 39473622)
-
(2004)
Circulation
, vol.110
, Issue.18
, pp. 2946-2951
-
-
Gruner, S.1
Prostredna, M.2
Aktas, B.3
Moers, A.4
Schulte, V.5
Krieg, T.6
Offermanns, S.7
Eckes, B.8
Nieswandt, B.9
-
28
-
-
33745939987
-
Two-phase antithrombotic protection after anti-glycoprotein VI treatment in mice
-
DOI 10.1161/01.ATV.0000225697.98093.ed, PII 0004360520060700000037
-
Schulte V, Reusch HP, Pozgajova M, Varga-Szabo D, Gachet C, Nieswandt B. Two-phase antithrombotic protection after anti-glycoprotein VI treatment in mice. Arterioscler Thromb Vasc Biol. 2006;26: 1640-1647. (Pubitemid 44288995)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.7
, pp. 1640-1647
-
-
Schulte, V.1
Reusch, H.P.2
Pozgajova, M.3
Varga-Szabo, D.4
Gachet, C.5
Nieswandt, B.6
-
29
-
-
51749083546
-
The immunoadhesin glycoprotein VI-Fc regulates arterial remodeling after mechanical injury in ApoE-/- mice
-
Schönberger T, Siegel-Axel D, Bussl R, Richter S, Judenhofer MS, Haubner R, Reischl G, Klingel K, Münch G, Seizer P, Pichler BJ, Gawaz M. The immunoadhesin glycoprotein VI-Fc regulates arterial remodeling after mechanical injury in ApoE-/- mice. Cardiovasc Res. 2008;80: 131-137.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 131-137
-
-
Schönberger, T.1
Siegel-Axel, D.2
Bussl, R.3
Richter, S.4
Judenhofer, M.S.5
Haubner, R.6
Reischl, G.7
Klingel, K.8
Münch, G.9
Seizer, P.10
Pichler, B.J.11
Gawaz, M.12
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