Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity

Reproductive Toxicology

Volumn 70, Issue , 2017, Pages 70-81

  Tal, Tamara ^a   Kilty, Claire ^b   Smith, Andrew ^b   LaLone, Carlie ^c   Kennedy, Brendán ^b   Tennant, Alan ^a   McCollum, Catherine W ^d   Bondesson, Maria ^d,e   Knudsen, Thomas ^a   Padilla, Stephanie ^a   Kleinstreuer, Nicole ^f  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c US EPA ORD NHEERL MED   (United States)

^d University of Houston   (United States)

^e UNIVERSITY OF HOUSTON   (United States)

^f NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Angiogenic inhibition; Predictive toxicology; Zebrafish

Indexed keywords

ANGIOGENESIS INHIBITOR; VASCULAR TARGETING AGENT; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; DEVELOPMENTAL TOXICITY; DEVELOPMENTAL VASCULAR TOXICITY; DRUG SCREENING; EMBRYO; EMBRYO DEVELOPMENT; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MODEL; NONHUMAN; PREDICTION; TOXICITY TESTING; TRANSGENIC ANIMAL; ZEBRA FISH; ANIMAL; ANIMAL MODEL; CARDIOVASCULAR SYSTEM; DRUG EFFECTS; EMBRYOLOGY; GENETICS; NONMAMMALIAN EMBRYO; POLLUTANT; TOXICITY; VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARDIOVASCULAR SYSTEM; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; ENVIRONMENTAL POLLUTANTS; GREEN FLUORESCENT PROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; MODELS, ANIMAL; NEOVASCULARIZATION, PHYSIOLOGIC; ZEBRAFISH;

EID: 85009253008     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2016.12.004     Document Type: Article

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