-
1
-
-
33751213587
-
The asthma epidemic
-
1 Eder, W., Ege, M.J., von Mutius, E., The asthma epidemic. N Engl J Med 355 (2006), 2226–2235.
-
(2006)
N Engl J Med
, vol.355
, pp. 2226-2235
-
-
Eder, W.1
Ege, M.J.2
von Mutius, E.3
-
2
-
-
84883598850
-
Genome-wide association studies in asthma; perhaps, the end of the beginning
-
2 Lockett, G.A., Holloway, J.W., Genome-wide association studies in asthma; perhaps, the end of the beginning. Curr Opin Allergy Clin Immunol 13 (2013), 463–469.
-
(2013)
Curr Opin Allergy Clin Immunol
, vol.13
, pp. 463-469
-
-
Lockett, G.A.1
Holloway, J.W.2
-
3
-
-
40049100646
-
Discovering susceptibility genes for asthma and allergy
-
3 Vercelli, D., Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 8 (2008), 169–182.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 169-182
-
-
Vercelli, D.1
-
4
-
-
0031954851
-
The genetics of asthma. Maternal effects in atopic disease
-
discussion 65–6
-
4 Moffatt, M.F., Cookson, W.O., The genetics of asthma. Maternal effects in atopic disease. Clin Exp Allergy 28:suppl 1 (1998), 56–61 discussion 65–6.
-
(1998)
Clin Exp Allergy
, vol.28
, pp. 56-61
-
-
Moffatt, M.F.1
Cookson, W.O.2
-
5
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
5 Jirtle, R.L., Skinner, M.K., Environmental epigenomics and disease susceptibility. Nat Rev Genet 8 (2007), 253–262.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
6
-
-
33646012294
-
T helper cell differentiation: regulation by cis elements and epigenetics
-
6 Lee, G.R., Kim, S.T., Spilianakis, C.G., Fields, P.E., Flavell, R.A., T helper cell differentiation: regulation by cis elements and epigenetics. Immunity 24 (2006), 369–379.
-
(2006)
Immunity
, vol.24
, pp. 369-379
-
-
Lee, G.R.1
Kim, S.T.2
Spilianakis, C.G.3
Fields, P.E.4
Flavell, R.A.5
-
7
-
-
36749029364
-
Demethylation of a specific hypersensitive site in the Th2 locus control region
-
7 Kim, S.T., Fields, P.E., Flavell, R.A., Demethylation of a specific hypersensitive site in the Th2 locus control region. Proc Natl Acad Sci U S A 104 (2007), 17052–17057.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17052-17057
-
-
Kim, S.T.1
Fields, P.E.2
Flavell, R.A.3
-
8
-
-
33847005427
-
The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture
-
8 Webster, R.B., Rodriguez, Y., Klimecki, W.T., Vercelli, D., The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture. J Biol Chem 282 (2007), 700–709.
-
(2007)
J Biol Chem
, vol.282
, pp. 700-709
-
-
Webster, R.B.1
Rodriguez, Y.2
Klimecki, W.T.3
Vercelli, D.4
-
9
-
-
55849150592
-
In utero supplementation with methyl donors enhances allergic airway disease in mice
-
9 Hollingsworth, J.W., Maruoka, S., Boon, K., Garantziotis, S., Li, Z., Tomfohr, J., et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest 118 (2008), 3462–3469.
-
(2008)
J Clin Invest
, vol.118
, pp. 3462-3469
-
-
Hollingsworth, J.W.1
Maruoka, S.2
Boon, K.3
Garantziotis, S.4
Li, Z.5
Tomfohr, J.6
-
10
-
-
84949117071
-
DNA methylation changes and childhood asthma in the inner city
-
10 Yang, I.V., Pedersen, B.S., Liu, A.H., O'Connor, G.T., Teach, S.J., Kattan, M., et al. DNA methylation changes and childhood asthma in the inner city. J Allergy Clin Immunol 136 (2015), 69–80.
-
(2015)
J Allergy Clin Immunol
, vol.136
, pp. 69-80
-
-
Yang, I.V.1
Pedersen, B.S.2
Liu, A.H.3
O'Connor, G.T.4
Teach, S.J.5
Kattan, M.6
-
11
-
-
84928819497
-
An epigenome-wide association study of total serum immunoglobulin E concentration
-
11 Liang, L., Willis-Owen, S.A., Laprise, C., Wong, K.C., Davies, G.A., Hudson, T.J., et al. An epigenome-wide association study of total serum immunoglobulin E concentration. Nature 520 (2015), 670–674.
-
(2015)
Nature
, vol.520
, pp. 670-674
-
-
Liang, L.1
Willis-Owen, S.A.2
Laprise, C.3
Wong, K.C.4
Davies, G.A.5
Hudson, T.J.6
-
12
-
-
84877926713
-
House dust mite interactions with airway epithelium: role in allergic airway inflammation
-
12 Gandhi, V.D., Davidson, C., Asaduzzaman, M., Nahirney, D., Vliagoftis, H., House dust mite interactions with airway epithelium: role in allergic airway inflammation. Curr Allergy Asthma Rep 13 (2013), 262–270.
-
(2013)
Curr Allergy Asthma Rep
, vol.13
, pp. 262-270
-
-
Gandhi, V.D.1
Davidson, C.2
Asaduzzaman, M.3
Nahirney, D.4
Vliagoftis, H.5
-
13
-
-
84860691114
-
The airway epithelium in asthma
-
13 Lambrecht, B.N., Hammad, H., The airway epithelium in asthma. Nat Med 18 (2012), 684–692.
-
(2012)
Nat Med
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
14
-
-
84858234306
-
The clinical and environmental determinants of airway transcriptional profiles in allergic asthma
-
14 Yang, I.V., Tomfohr, J., Singh, J., Foss, C.M., Marshall, H.E., Que, L.G., et al. The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. Am J Respir Crit Care Med 185 (2012), 620–627.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 620-627
-
-
Yang, I.V.1
Tomfohr, J.2
Singh, J.3
Foss, C.M.4
Marshall, H.E.5
Que, L.G.6
-
15
-
-
35649028488
-
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
-
15 Woodruff, P.G., Boushey, H.A., Dolganov, G.M., Barker, C.S., Yang, Y.H., Donnelly, S., et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci U S A 104 (2007), 15858–15863.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15858-15863
-
-
Woodruff, P.G.1
Boushey, H.A.2
Dolganov, G.M.3
Barker, C.S.4
Yang, Y.H.5
Donnelly, S.6
-
16
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
16 Woodruff, P.G., Modrek, B., Choy, D.F., Jia, G., Abbas, A.R., Ellwanger, A., et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 180 (2009), 388–395.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
Jia, G.4
Abbas, A.R.5
Ellwanger, A.6
-
17
-
-
84896701857
-
Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease
-
17 Poole, A., Urbanek, C., Eng, C., Schageman, J., Jacobson, S., O'Connor, B.P., et al. Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease. J Allergy Clin Immunol 133 (2014), 670–678.e12.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 670-678.e12
-
-
Poole, A.1
Urbanek, C.2
Eng, C.3
Schageman, J.4
Jacobson, S.5
O'Connor, B.P.6
-
18
-
-
84857381360
-
Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function
-
18 Qiu, W., Baccarelli, A., Carey, V.J., Boutaoui, N., Bacherman, H., Klanderman, B., et al. Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med 185 (2012), 373–381.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 373-381
-
-
Qiu, W.1
Baccarelli, A.2
Carey, V.J.3
Boutaoui, N.4
Bacherman, H.5
Klanderman, B.6
-
19
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
19 Lister, R., Pelizzola, M., Dowen, R.H., Hawkins, R.D., Hon, G., Tonti-Filippini, J., et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462 (2009), 315–322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
-
20
-
-
84904751825
-
Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experiments
-
20 Dolzhenko, E., Smith, A.D., Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experiments. BMC Bioinformatics, 15, 2014, 215.
-
(2014)
BMC Bioinformatics
, vol.15
, pp. 215
-
-
Dolzhenko, E.1
Smith, A.D.2
-
21
-
-
84898679051
-
Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score
-
21 Marcucci, G., Yan, P., Maharry, K., Frankhouser, D., Nicolet, D., Metzeler, K.H., et al. Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score. J Clin Oncol 32 (2014), 548–556.
-
(2014)
J Clin Oncol
, vol.32
, pp. 548-556
-
-
Marcucci, G.1
Yan, P.2
Maharry, K.3
Frankhouser, D.4
Nicolet, D.5
Metzeler, K.H.6
-
22
-
-
84916200736
-
Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis
-
22 Yang, I.V., Pedersen, B.S., Rabinovich, E., Hennessy, C.E., Davidson, E.J., Murphy, E., et al. Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 190 (2014), 1263–1272.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 1263-1272
-
-
Yang, I.V.1
Pedersen, B.S.2
Rabinovich, E.3
Hennessy, C.E.4
Davidson, E.J.5
Murphy, E.6
-
23
-
-
84862173149
-
SWAN: subset-quantile within array normalization for Illumina Infinium HumanMethylation450 BeadChips
-
23 Maksimovic, J., Gordon, L., Oshlack, A., SWAN: subset-quantile within array normalization for Illumina Infinium HumanMethylation450 BeadChips. Genome Biol, 13, 2012, R44.
-
(2012)
Genome Biol
, vol.13
, pp. R44
-
-
Maksimovic, J.1
Gordon, L.2
Oshlack, A.3
-
24
-
-
77955505742
-
A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
-
24 Stegle, O., Parts, L., Durbin, R., Winn, J., A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comp Biol, 6, 2010, e1000770.
-
(2010)
PLoS Comp Biol
, vol.6
, pp. e1000770
-
-
Stegle, O.1
Parts, L.2
Durbin, R.3
Winn, J.4
-
25
-
-
4544341015
-
Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
-
Article3
-
25 Smyth, G.K., Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol, 3, 2004 Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
26
-
-
84869421697
-
Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values
-
26 Pedersen, B.S., Schwartz, D.A., Yang, I.V., Kechris, K.J., Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values. Bioinformatics 28 (2012), 2986–2988.
-
(2012)
Bioinformatics
, vol.28
, pp. 2986-2988
-
-
Pedersen, B.S.1
Schwartz, D.A.2
Yang, I.V.3
Kechris, K.J.4
-
27
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
27 Benjamini, Y., Hochberg, Y., Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57 (1995), 289–300.
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
28
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
28 Zhang, D., Cheng, L., Badner, J.A., Chen, C., Chen, Q., Luo, W., et al. Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet 86 (2010), 411–419.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.A.3
Chen, C.4
Chen, Q.5
Luo, W.6
-
29
-
-
84866163733
-
Genomics: ENCODE leads the way on big data
-
29 Gerstein, M., Genomics: ENCODE leads the way on big data. Nature, 489, 2012, 208.
-
(2012)
Nature
, vol.489
, pp. 208
-
-
Gerstein, M.1
-
30
-
-
84887516690
-
Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression
-
30 Buro-Auriemma, L.J., Salit, J., Hackett, N.R., Walters, M.S., Strulovici-Barel, Y., Staudt, M.R., et al. Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression. Hum Mol Genet 22 (2013), 4726–4738.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4726-4738
-
-
Buro-Auriemma, L.J.1
Salit, J.2
Hackett, N.R.3
Walters, M.S.4
Strulovici-Barel, Y.5
Staudt, M.R.6
-
31
-
-
84884297351
-
An expression atlas of human primary cells: inference of gene function from coexpression networks
-
31 Mabbott, N.A., Baillie, J.K., Brown, H., Freeman, T.C., Hume, D.A., An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics, 14, 2013, 632.
-
(2013)
BMC Genomics
, vol.14
, pp. 632
-
-
Mabbott, N.A.1
Baillie, J.K.2
Brown, H.3
Freeman, T.C.4
Hume, D.A.5
-
32
-
-
84866728729
-
Consortium biology in immunology: the perspective from the Immunological Genome Project
-
32 Benoist, C., Lanier, L., Merad, M., Mathis, D., Consortium biology in immunology: the perspective from the Immunological Genome Project. Nat Rev Immunol 12 (2012), 734–740.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 734-740
-
-
Benoist, C.1
Lanier, L.2
Merad, M.3
Mathis, D.4
-
33
-
-
77951672627
-
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma
-
33 Dougherty, R.H., Sidhu, S.S., Raman, K., Solon, M., Solberg, O.D., Caughey, G.H., et al. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol 125 (2010), 1046–1053.e8.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1046-1053.e8
-
-
Dougherty, R.H.1
Sidhu, S.S.2
Raman, K.3
Solon, M.4
Solberg, O.D.5
Caughey, G.H.6
-
34
-
-
84863986133
-
Functions of DNA methylation: islands, start sites, gene bodies and beyond
-
34 Jones, P.A., Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 13 (2012), 484–492.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
35
-
-
84904801714
-
NetworkAnalyst—integrative approaches for protein-protein interaction network analysis and visual exploration
-
35 Xia, J., Benner, M.J., Hancock, R.E., NetworkAnalyst—integrative approaches for protein-protein interaction network analysis and visual exploration. Nucleic Acids Res 42 (2014), W167–W174.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. W167-W174
-
-
Xia, J.1
Benner, M.J.2
Hancock, R.E.3
-
36
-
-
84925003052
-
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
-
36 Nachbur, U., Stafford, C.A., Bankovacki, A., Zhan, Y., Lindqvist, L.M., Fiil, B.K., et al. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun, 6, 2015, 6442.
-
(2015)
Nat Commun
, vol.6
, pp. 6442
-
-
Nachbur, U.1
Stafford, C.A.2
Bankovacki, A.3
Zhan, Y.4
Lindqvist, L.M.5
Fiil, B.K.6
-
37
-
-
84883403406
-
Receptor-interacting protein 2 gene silencing attenuates allergic airway inflammation
-
37 Goh, F.Y., Cook, K.L., Upton, N., Tao, L., Lah, L.C., Leung, B.P., et al. Receptor-interacting protein 2 gene silencing attenuates allergic airway inflammation. J Immunol 191 (2013), 2691–2699.
-
(2013)
J Immunol
, vol.191
, pp. 2691-2699
-
-
Goh, F.Y.1
Cook, K.L.2
Upton, N.3
Tao, L.4
Lah, L.C.5
Leung, B.P.6
-
38
-
-
84964325206
-
Genome-wide methylation study identifies an IL-13-induced epigenetic signature in asthmatic airways
-
38 Nicodemus-Johnson, J., Naughton, K.A., Sudi, J., Hogarth, K., Naurekas, E.T., Nicolae, D.L., et al. Genome-wide methylation study identifies an IL-13-induced epigenetic signature in asthmatic airways. Am J Respir Crit Care Med 193 (2016), 376–385.
-
(2016)
Am J Respir Crit Care Med
, vol.193
, pp. 376-385
-
-
Nicodemus-Johnson, J.1
Naughton, K.A.2
Sudi, J.3
Hogarth, K.4
Naurekas, E.T.5
Nicolae, D.L.6
-
39
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
39 Liu, Y., Aryee, M.J., Padyukov, L., Fallin, M.D., Hesselberg, E., Runarsson, A., et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol 31 (2013), 142–147.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 142-147
-
-
Liu, Y.1
Aryee, M.J.2
Padyukov, L.3
Fallin, M.D.4
Hesselberg, E.5
Runarsson, A.6
-
40
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
40 Irizarry, R.A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C., Onyango, P., et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 41 (2009), 178–186.
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
-
41
-
-
78349252117
-
12/15-lipoxygenase is an interleukin-13 and interferon-gamma counterregulated-mediator of allergic airway inflammation
-
41 Lindley, A.R., Crapster-Pregont, M., Liu, Y., Kuperman, D.A., 12/15-lipoxygenase is an interleukin-13 and interferon-gamma counterregulated-mediator of allergic airway inflammation. Mediators Inflamm, 2010, 2010, 10.1155/2010/727305.
-
(2010)
Mediators Inflamm
, vol.2010
-
-
Lindley, A.R.1
Crapster-Pregont, M.2
Liu, Y.3
Kuperman, D.A.4
-
42
-
-
84870254020
-
Calpain and MARCKS protein regulation of airway mucin secretion
-
42 Lampe, W.R., Park, J., Fang, S., Crews, A.L., Adler, K.B., Calpain and MARCKS protein regulation of airway mucin secretion. Pulm Pharmacol Ther 25 (2012), 427–431.
-
(2012)
Pulm Pharmacol Ther
, vol.25
, pp. 427-431
-
-
Lampe, W.R.1
Park, J.2
Fang, S.3
Crews, A.L.4
Adler, K.B.5
-
43
-
-
84857134135
-
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
-
43 Lefrancais, E., Roga, S., Gautier, V., Gonzalez-de-Peredo, A., Monsarrat, B., Girard, J.P., et al. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci U S A 109 (2012), 1673–1678.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1673-1678
-
-
Lefrancais, E.1
Roga, S.2
Gautier, V.3
Gonzalez-de-Peredo, A.4
Monsarrat, B.5
Girard, J.P.6
-
44
-
-
84881533239
-
Cystatin SN upregulation in patients with seasonal allergic rhinitis
-
44 Imoto, Y., Tokunaga, T., Matsumoto, Y., Hamada, Y., Ono, M., Yamada, T., et al. Cystatin SN upregulation in patients with seasonal allergic rhinitis. PLoS One, 8, 2013, e67057.
-
(2013)
PLoS One
, vol.8
, pp. e67057
-
-
Imoto, Y.1
Tokunaga, T.2
Matsumoto, Y.3
Hamada, Y.4
Ono, M.5
Yamada, T.6
-
45
-
-
30344450433
-
Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways
-
45 Candiano, G., Bruschi, M., Pedemonte, N., Caci, E., Liberatori, S., Bini, L., et al. Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways. Am J Respir Crit Care Med 172 (2005), 1090–1096.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1090-1096
-
-
Candiano, G.1
Bruschi, M.2
Pedemonte, N.3
Caci, E.4
Liberatori, S.5
Bini, L.6
-
46
-
-
0041622813
-
The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma
-
46 Nassenstein, C., Braun, A., Erpenbeck, V.J., Lommatzsch, M., Schmidt, S., Krug, N., et al. The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. J Exp Med 198 (2003), 455–467.
-
(2003)
J Exp Med
, vol.198
, pp. 455-467
-
-
Nassenstein, C.1
Braun, A.2
Erpenbeck, V.J.3
Lommatzsch, M.4
Schmidt, S.5
Krug, N.6
-
47
-
-
80053424583
-
Lung homing of endothelial progenitor cells in humans with asthma after allergen challenge
-
47 Imaoka, H., Punia, N., Irshad, A., Ying, S., Corrigan, C.J., Howie, K., et al. Lung homing of endothelial progenitor cells in humans with asthma after allergen challenge. Am J Respir Crit Care Med 184 (2011), 771–778.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 771-778
-
-
Imaoka, H.1
Punia, N.2
Irshad, A.3
Ying, S.4
Corrigan, C.J.5
Howie, K.6
-
48
-
-
84896295497
-
Interleukin-4-mediated 15-lipoxygenase-1 trans-activation requires UTX recruitment and H3K27me3 demethylation at the promoter in A549 cells
-
48 Han, H., Xu, D., Liu, C., Claesson, H.E., Bjorkholm, M., Sjoberg, J., Interleukin-4-mediated 15-lipoxygenase-1 trans-activation requires UTX recruitment and H3K27me3 demethylation at the promoter in A549 cells. PLoS One, 9, 2014, e85085.
-
(2014)
PLoS One
, vol.9
, pp. e85085
-
-
Han, H.1
Xu, D.2
Liu, C.3
Claesson, H.E.4
Bjorkholm, M.5
Sjoberg, J.6
-
49
-
-
84907011938
-
Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice
-
49 Yu, D.H., Waterland, R.A., Zhang, P., Schady, D., Chen, M.H., Guan, Y., et al. Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice. J Clin Invest 124 (2014), 3708–3712.
-
(2014)
J Clin Invest
, vol.124
, pp. 3708-3712
-
-
Yu, D.H.1
Waterland, R.A.2
Zhang, P.3
Schady, D.4
Chen, M.H.5
Guan, Y.6
-
50
-
-
21044439177
-
Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes
-
50 Kaminskas, E., Farrell, A., Abraham, S., Baird, A., Hsieh, L.S., Lee, S.L., et al. Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. Clin Cancer Res 11 (2005), 3604–3608.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3604-3608
-
-
Kaminskas, E.1
Farrell, A.2
Abraham, S.3
Baird, A.4
Hsieh, L.S.5
Lee, S.L.6
-
51
-
-
36448973492
-
Decitabine in the treatment of myelodysplastic syndromes
-
51 Saba, H.I., Decitabine in the treatment of myelodysplastic syndromes. Ther Clin Risk Manage 3 (2007), 807–817.
-
(2007)
Ther Clin Risk Manage
, vol.3
, pp. 807-817
-
-
Saba, H.I.1
-
52
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
52 Brock, M.V., Hooker, C.M., Ota-Machida, E., Han, Y., Guo, M., Ames, S., et al. DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med 358 (2008), 1118–1128.
-
(2008)
N Engl J Med
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
-
53
-
-
84655163371
-
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
-
53 Juergens, R.A., Wrangle, J., Vendetti, F.P., Murphy, S.C., Zhao, M., Coleman, B., et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov 1 (2011), 598–607.
-
(2011)
Cancer Discov
, vol.1
, pp. 598-607
-
-
Juergens, R.A.1
Wrangle, J.2
Vendetti, F.P.3
Murphy, S.C.4
Zhao, M.5
Coleman, B.6
-
54
-
-
84857295742
-
Nasal cell DNA methylation, inflammation, lung function and wheezing in children with asthma
-
54 Baccarelli, A., Rusconi, F., Bollati, V., Catelan, D., Accetta, G., Hou, L., et al. Nasal cell DNA methylation, inflammation, lung function and wheezing in children with asthma. Epigenomics 4 (2012), 91–100.
-
(2012)
Epigenomics
, vol.4
, pp. 91-100
-
-
Baccarelli, A.1
Rusconi, F.2
Bollati, V.3
Catelan, D.4
Accetta, G.5
Hou, L.6
-
55
-
-
84860624014
-
DNA Hypomethylation at ALOX12 Is Associated with Persistent Wheezing in Childhood
-
55 Morales, E., Bustamante, M., Vilahur, N., Escaramis, G., Montfort, M., de Cid, R., et al. DNA Hypomethylation at ALOX12 Is Associated with Persistent Wheezing in Childhood. Am J Respir Crit Care Med 185 (2012), 937–943.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 937-943
-
-
Morales, E.1
Bustamante, M.2
Vilahur, N.3
Escaramis, G.4
Montfort, M.5
de Cid, R.6
-
56
-
-
84880391047
-
Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma
-
56 Rastogi, D., Suzuki, M., Greally, J.M., Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma. Sci Rep, 3, 2013, 2164.
-
(2013)
Sci Rep
, vol.3
, pp. 2164
-
-
Rastogi, D.1
Suzuki, M.2
Greally, J.M.3
-
57
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
57 Hansen, K.D., Timp, W., Bravo, H.C., Sabunciyan, S., Langmead, B., McDonald, O.G., et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 43 (2011), 768–775.
-
(2011)
Nat Genet
, vol.43
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
Sabunciyan, S.4
Langmead, B.5
McDonald, O.G.6
-
58
-
-
84906837231
-
Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors
-
58 Timp, W., Bravo, H.C., McDonald, O.G., Goggins, M., Umbricht, C., Zeiger, M., Feinberg, A.P., Irizarry, R.A., Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors. Genome Med, 6, 2014, 61.
-
(2014)
Genome Med
, vol.6
, pp. 61
-
-
Timp, W.1
Bravo, H.C.2
McDonald, O.G.3
Goggins, M.4
Umbricht, C.5
Zeiger, M.6
Feinberg, A.P.7
Irizarry, R.A.8
-
59
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
59 Ball, M.P., Li, J.B., Gao, Y., Lee, J.H., LeProust, E.M., Park, I.H., et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 27 (2009), 361–368.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
Lee, J.H.4
LeProust, E.M.5
Park, I.H.6
-
60
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
60 Kulis, M., Heath, S., Bibikova, M., Queiros, A.C., Navarro, A., Clot, G., et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet 44 (2012), 1236–1242.
-
(2012)
Nat Genet
, vol.44
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
Queiros, A.C.4
Navarro, A.5
Clot, G.6
-
61
-
-
84863509978
-
Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome
-
61 Wan, E.S., Qiu, W., Baccarelli, A., Carey, V.J., Bacherman, H., Rennard, S.I., et al. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet 21 (2012), 3073–3082.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3073-3082
-
-
Wan, E.S.1
Qiu, W.2
Baccarelli, A.3
Carey, V.J.4
Bacherman, H.5
Rennard, S.I.6
-
62
-
-
65249142729
-
Rapid DNA methylation changes after exposure to traffic particles
-
62 Baccarelli, A., Wright, R.O., Bollati, V., Tarantini, L., Litonjua, A.A., Suh, H.H., et al. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 179 (2009), 572–578.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 572-578
-
-
Baccarelli, A.1
Wright, R.O.2
Bollati, V.3
Tarantini, L.4
Litonjua, A.A.5
Suh, H.H.6
-
63
-
-
84873725239
-
Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy
-
63 Michel, S., Busato, F., Genuneit, J., Pekkanen, J., Dalphin, J.C., Riedler, J., et al. Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy. Allergy 68 (2013), 355–364.
-
(2013)
Allergy
, vol.68
, pp. 355-364
-
-
Michel, S.1
Busato, F.2
Genuneit, J.3
Pekkanen, J.4
Dalphin, J.C.5
Riedler, J.6
-
64
-
-
84986302076
-
DNA methylation of the allergy regulatory gene interferon gamma varies by age, sex, and tissue type in asthmatics
-
64 Lovinsky-Desir, S., Ridder, R., Torrone, D., Maher, C., Narula, S., Scheuerman, M., et al. DNA methylation of the allergy regulatory gene interferon gamma varies by age, sex, and tissue type in asthmatics. Clin Epigenetics, 6, 2014, 9.
-
(2014)
Clin Epigenetics
, vol.6
, pp. 9
-
-
Lovinsky-Desir, S.1
Ridder, R.2
Torrone, D.3
Maher, C.4
Narula, S.5
Scheuerman, M.6
-
65
-
-
84902751799
-
Human rhinovirus infection causes different DNA methylation changes in nasal epithelial cells from healthy and asthmatic subjects
-
65 McErlean, P., Favoreto, S. Jr., Costa, F.F., Shen, J., Quraishi, J., Biyasheva, A., et al. Human rhinovirus infection causes different DNA methylation changes in nasal epithelial cells from healthy and asthmatic subjects. BMC Med Genomics, 7, 2014, 37.
-
(2014)
BMC Med Genomics
, vol.7
, pp. 37
-
-
McErlean, P.1
Favoreto, S.2
Costa, F.F.3
Shen, J.4
Quraishi, J.5
Biyasheva, A.6
-
66
-
-
84876419289
-
African ancestry is a risk factor for asthma and high total IgE levels in African admixed populations
-
66 Vergara, C., Murray, T., Rafaels, N., Lewis, R., Campbell, M., Foster, C., et al. African ancestry is a risk factor for asthma and high total IgE levels in African admixed populations. Genet Epidemiol 37 (2013), 393–401.
-
(2013)
Genet Epidemiol
, vol.37
, pp. 393-401
-
-
Vergara, C.1
Murray, T.2
Rafaels, N.3
Lewis, R.4
Campbell, M.5
Foster, C.6
-
67
-
-
84905595372
-
Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study
-
67 Galanter, J.M., Gignoux, C.R., Torgerson, D.G., Roth, L.A., Eng, C., Oh, S.S., et al. Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. J Allergy Clin Immunol 134 (2014), 295–305.
-
(2014)
J Allergy Clin Immunol
, vol.134
, pp. 295-305
-
-
Galanter, J.M.1
Gignoux, C.R.2
Torgerson, D.G.3
Roth, L.A.4
Eng, C.5
Oh, S.S.6
-
68
-
-
78651552406
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
68 Bell, J.T., Pai, A.A., Pickrell, J.K., Gaffney, D.J., Pique-Regi, R., Degner, J.F., et al. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol, 12, 2011, R10.
-
(2011)
Genome Biol
, vol.12
, pp. R10
-
-
Bell, J.T.1
Pai, A.A.2
Pickrell, J.K.3
Gaffney, D.J.4
Pique-Regi, R.5
Degner, J.F.6
-
69
-
-
84856791176
-
Population-specificity of human DNA methylation
-
69 Fraser, H.B., Lam, L.L., Neumann, S.M., Kobor, M.S., Population-specificity of human DNA methylation. Genome Biol, 13, 2012, R8.
-
(2012)
Genome Biol
, vol.13
, pp. R8
-
-
Fraser, H.B.1
Lam, L.L.2
Neumann, S.M.3
Kobor, M.S.4
-
70
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
70 Branco, M.R., Ficz, G., Reik, W., Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 13 (2012), 7–13.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
|