Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 3, 2014, Pages

  Poole, Alex ^a   Urbanek, Cydney ^a   Eng, Celeste ^b   Schageman, Jeoffrey ^d   Jacobson, Sean ^e   O'Connor, Brian P ^a,f   Galanter, Joshua M ^b,c   Gignoux, Christopher R ^b,c   Roth, Lindsey A ^b   Kumar, Rajesh ^g   Lutz, Sharon ^e   Liu, Andrew H ^a   Fingerlin, Tasha E ^e   Setterquist, Robert A ^d   Burchard, Esteban G ^b,c   Rodriguez Santana, Jose ^h   Seibold, Max A ^a,f  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Life Technologies   (United States)

^e Global Health and Health Disparities   (United States)

^f UNIVERSITY OF COLORADO   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

^h Centro de Neumolo ia Pediatrica   (Puerto Rico)

Author keywords

asthma; bronchial airway epithelium; Nasal airway epithelium; transcriptome

Indexed keywords

CALCIUM ACTIVATED CHLORIDE CHANNEL; INTERLEUKIN 13; INTERLEUKIN 5; SERINE PROTEINASE INHIBITOR; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTOME;

ADOLESCENT; ALLERGIC ASTHMA; ARTICLE; ASTHMA; CLUSTER ANALYSIS; CONTROLLED STUDY; DISEASE EXACERBATION; EOSINOPHIL COUNT; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RHINITIS; RNA SEQUENCE; TH2 CELL; TRANSCRIPTOMICS;

ASTHMA; BRONCHIAL AIRWAY EPITHELIUM; NASAL AIRWAY EPITHELIUM; T(H)2; TRANSCRIPTOME;

ADOLESCENT; ASTHMA; BRONCHI; FEMALE; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTERLEUKIN-13; MALE; NASAL MUCOSA; PHENOTYPE; TH2 CELLS;

EID: 84896701857     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.11.025     Document Type: Article

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