Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages

Journal of Leukocyte Biology

Volumn 101, Issue 1, 2017, Pages 205-215

  Yeon, Sang Hyeon ^a   Yang, Gabsik ^a   Lee, Hye Eun ^a   Lee, Joo Young ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Danger signal; Inflammation; Interleukin 1 ; Oxidized phospholipid; Reactive oxygen species

Indexed keywords

1 PALMITOYL 2 (5 OXOVALEROYL) SN GLYCERO PHOSPHOCHOLINE; CALCIUM ION; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PHOSPHATIDYLCHOLINE; POTASSIUM; PROTEIN; PROTEIN ASC; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 1-PALMITOYL-2-(5-OXOVALEROYL)-SN-GLYCERO-3-PHOSPHORYLCHOLINE; APOPTOSIS REGULATORY PROTEIN; CALCIUM; CYCLOSPORIN; ETHER PHOSPHOLIPID; NLRP3 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

AIR POUCH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; IMMUNOBLOTTING; LIPID OXIDATION; MITOCHONDRION; MOUSE; NONHUMAN; OLIGOMERIZATION; PERITONITIS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN CLEAVAGE; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; INTRACELLULAR SPACE; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PATHOLOGY; PHAGOCYTOSIS; PROTEIN DEGRADATION; PROTEIN MULTIMERIZATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; CASPASE 1; CELLS, CULTURED; CYCLOSPORINE; DISEASE MODELS, ANIMAL; INFLAMMASOMES; INTERLEUKIN-1BETA; INTRACELLULAR SPACE; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERITONITIS; PHAGOCYTOSIS; PHOSPHOLIPID ETHERS; POTASSIUM; PROTEIN MULTIMERIZATION; PROTEOLYSIS; REACTIVE OXYGEN SPECIES;

EID: 85008452927     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3VMA1215-579RR     Document Type: Article

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