Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression

Laboratory Investigation

Volumn 97, Issue 1, 2017, Pages 14-23

  Wu, Richard L ^a,b   Vazquez Roque, Maria I ^c   Carlson, Paula ^c   Burton, Duane ^c   Grover, Madhusudan ^c   Camilleri, Michael ^c   Turner, Jerrold R ^a,d  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Clinical Enteric Neuroscience Translational and Epidemiological Research Mayo Clinic   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN; CLAUDIN 15; CLAUDIN 2; CLAUDIN 8; GLUTEN; MYOSIN II; MYOSIN LIGHT CHAIN KINASE; SODIUM CHANNEL; UNCLASSIFIED DRUG; MYOSIN LIGHT CHAIN;

ARTICLE; BODY MASS; CLINICAL ARTICLE; COLON BIOPSY; COLON CELL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DUODENUM BIOPSY; ENZYME PHOSPHORYLATION; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE CELL; IRRITABLE COLON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RANDOMIZED CONTROLLED TRIAL; TIGHT JUNCTION; ADULT; COLON; DRUG EFFECTS; FEMALE; GLUTEN FREE DIET; INTESTINE; IRRITABLE BOWEL SYNDROME; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PERMEABILITY; PHOSPHORYLATION;

ADULT; CLAUDIN-2; CLAUDINS; COLON; DIARRHEA; DIET, GLUTEN-FREE; FEMALE; GLUTENS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINES; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PERMEABILITY; PHOSPHORYLATION; TIGHT JUNCTIONS;

EID: 85008311673     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2016.118     Document Type: Article

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