Crystal structure of a claudin provides insight into the architecture of tight junctions

Science

Volumn 344, Issue 6181, 2014, Pages 304-307

  Suzuki, Hiroshi ^a   Nishizawa, Tomohiro ^b,c   Tani, Kazutoshi ^a   Yamazaki, Yuji ^d,e   Tamura, Atsushi ^d   Ishitani, Ryuichiro ^b,c   Dohmae, Naoshi ^c   Tsukita, Sachiko ^d   Nureki, Osamu ^b,c   Fujiyoshi, Yoshinori ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c RIKEN   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN; CLAUDIN 15; ION; UNCLASSIFIED DRUG; PROTEIN SUBUNIT;

CYTOLOGY; HOMEOSTASIS; MEMBRANE; MOLECULAR ANALYSIS; PERMEABILITY;

ARTICLE; BETA SHEET; CRYSTAL STRUCTURE; HOMEOSTASIS; PRIORITY JOURNAL; TIGHT JUNCTION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; STATIC ELECTRICITY; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CLAUDINS; CRYSTALLOGRAPHY, X-RAY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; STATIC ELECTRICITY; TIGHT JUNCTIONS;

EID: 84899490629     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1248571     Document Type: Article

References (29)

1. D. W. Powell, Am. J. Physiol. 241, G275-G288 (1981).
2. E. E. Schneeberger, R. D. Lynch, Am. J. Physiol. 262, L647-L661 (1992).
3. V. W. Tang, D. A. Goodenough, Biophys. J. 84, 1660-1673 (2003).
4. C. M. Van Itallie, J. M. Anderson, Annu. Rev. Physiol. 68, 403-429 (2006).
5. L. A. Staehelin, J. Cell Sci. 13, 763-786 (1973).
6. E. E. Schneeberger, R. D. Lynch, Am. J. Physiol. Cell Physiol. 286, C1213-C1228 (2004).
7. M. Furuse, K. Fujita, T. Hiiragi, K. Fujimoto, S. Tsukita, J. Cell Biol. 141, 1539-1550 (1998).
8. M. Furuse, H. Sasaki, K. Fujimoto, S. Tsukita, J. Cell Biol. 143, 391-401 (1998).
9. S. Tsukita, M. Furuse, M. Itoh, Nat. Rev. Mol. Cell Biol. 2, 285-293 (2001).
10. K. Mineta et al., FEBS Lett. 585, 606-612 (2011).
11. D. B. Simon et al., Science 285, 103-106 (1999).
12. S. Hadj-Rabia et al., Gastroenterology 127, 1386-1390 (2004).
13. E. R. Wilcox et al., Cell 104, 165-172 (2001).
14. M. J. Evans et al., Nature 446, 801-805 (2007).
15. D. Günzel, A. S. L. Yu, Physiol. Rev. 93, 525-569 (2013).
16. M. Furuse, S. Tsukita, Trends Cell Biol. 16, 181-188 (2006).
17. S. Angelow, R. Ahlstrom, A. S. L. Yu, Am. J. Physiol. Renal Physiol. 295, F867-F876 (2008).
18. B. Hille, Ion Channels of Excitable Membranes (Sinauer Associates, Sunderland, MA, ed. 3, 2001).
19. G. E. Schulz, Curr. Opin. Struct. Biol. 10, 443-447 (2000).
20. S. H. White, Nature 459, 344-346 (2009).
21. See supplementary materials on Science Online.
22. K. Hirata et al., AIP Conf. Proc. 1234, 901-904 (2010).
23. J. Li, S. Angelow, A. Linge, M. Zhuo, A. S. L. Yu, Am. J. Physiol. Cell Physiol. 305, C190-C196 (2013).
24. J. M. Anderson, C. M. Van Itallie, Cold Spring Harb. Perspect. Biol. 1, a002584 (2009).
25. S. M. Krug et al., Ann. N.Y. Acad. Sci. 1257, 20-28 (2012).
26. A. Tamura et al., Gastroenterology 140, 913-923 (2011).
27. M. Wada, A. Tamura, N. Takahashi, S. Tsukita, Gastroenterology 144, 369-380 (2013).
28. O. R. Colegio, C. M. Van Itallie, H. J. McCrea, C. Rahner, J. M. Anderson, Am. J. Physiol. Cell Physiol. 283, C142-C147 (2002).
29. A. S. L. Yu et al., J. Gen. Physiol. 133, 111-127 (2009).