Surface-enhanced raman scattering (SERS) in bioscience: A review of application

Optical Spectroscopy and Computational Methods in Biology and Medicine

Volumn , Issue , 2014, Pages 29-59

  Bukowska, Jolanta ^a   Piotrowski, Piotr ^a  

^a UNIVERSITY OF WARSAW   (Poland)

Author keywords

Biosensors; Intracellular SERS; Nanoparticle probes; SERS of biological molecules; Surface enhanced Raman scattering (SERS)

Indexed keywords

BIOSENSORS; MOLECULES; NANOPARTICLES; PLASMONICS; RAMAN SCATTERING; SUBSTRATES;

BIOLOGICAL MOLECULE; DETECTION AND IDENTIFICATIONS; INTRACELLULAR SERS; METALLIC NANOSTRUCTURE; NANOPARTICLE PROBES; PLASMONIC NANOPARTICLE; SURFACE ENHANCED RAMAN SCATTERING (SERS); SURFACE-ENHANCED RAMAN SCATTERING SPECTROSCOPIES;

SURFACE SCATTERING;

EID: 85007127260     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-007-7832-0_3     Document Type: Chapter

References (172)

1. Fleischmann M, Hendra PJ, McQuillan AJ (1974) Raman spectra of pyridine adsorbed at a silver electrode. Chem Phys Lett 26(2):163-166
2. Jeanmaire DL, Van Duyne RP (1977) Surface Raman spectroelectrochemistry. Part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode. J Electroanal Chem Interfacial Electrochem 84(1):1-20
3. Lombardi JR, Birke RL, Lu T, Xu J (1986) Charge-transfer theory of surface enhanced Raman spectroscopy: Herzberg-Teller contributions. J Chem Phys 84:4174-4180
4. Pines D (1956) Collective energy losses in solids. Rev Mod Phys 28:184-198
5. Stern EA, Ferrell RA (1960) Surface plasma oscillations of a degenerate electron gas. Phys Rev 120:130-136
6. Le Ru EC, Blackie E, Meyer M, Etchegoin PG (2007) Surface enhanced Raman scattering enhancement factors: a comprehensive study. J Phys Chem C 111:13794-13803
7. Kottmann JP, Martin OJF, Smith DR, Schultz S (2001) Dramatic localized electromagnetic enhancement in plasmon resonant nanowires. Chem Phys Lett 341:1-6
8. Creighton JA (1988) The selection rules for surface-enhanced Raman spectroscopy. In:Clark RJH, Hester RE (eds) Spectroscopy of surfaces. Advances in Spectroscopy, vol 16. Wiley, New York, pp 37-89
9. Creighton A, Blatchford CG, Albrecht MG (1979) Plasma resonance enhancement of Raman scattering by pyridine adsorbed on silver and gold sol particles of size comparable to the excitation wavelength. J Chem Soc Faraday Trans 2 75:790-798
10. Lee PC, Meisel D (1982) Adsorption and surface-enhanced Raman of dyes on silver and gold sols. J Phys Chem 86:3391-3395
11. Leopold N, Lendl B (2003) A new method for fast preparation of highly surface-enhanced Raman scattering (SERS) active silver colloids at room temperature by reduction of silver nitrate with hydroxylamine hydrochloride. J Phys Chem B 107(24):5723-5727
12. Blatchford CG, Campbell JR, Creighton JA (1982) Plasma resonance enhanced Raman scattering by adsorbates on gold colloids: the effects of aggregation. Surf Sci 120:435-455
13. Larmour IA, Faulds K, Graham D (2012) SERS activity and stability of the most frequently used silver colloids. J Raman Spectrosc 43:202-206
14. Chumanov G, Sokolov K, Gregory BW, Cotton TM (1995) Colloidal metal films as a substrate for surface-enhanced spectroscopy. J Phys Chem 99:9466-9471
15. Grabar KC, Brown KR, Keating CD, Stranick SJ, Tang SL, Natan MJ (1997) Nanoscale characterization of gold colloid monolayers: a comparison of four techniques. Anal Chem 69:471-477
16. Fan M, Brolo AG (2009) Silver nanoparticles self assembly as SERS substrates with near single molecule detection limit. Phys Chem Chem Phys 11:7381-7389
17. Andrade GFS, Fan MK, Brolo AG (2010) Multilayer silver nanoparticles-modified optical fiber tip for high performance SERS remote sensing. Biosens Bioelectron 25:2270-2275
18. Addison CJ, Brolo AG (2006) Nanoparticle-containing structures as a substrate for surfaceenhanced Raman scattering. Langmuir 22:8696-870
19. Li X, Xu W, Zhang J, Jia H, Yang B, Zhao B, Li B, Ozaki Y (2004) Self-assembled metal colloid films: two approaches for preparing new SERS active substrates. Langmuir 20:1298-1304
20. Tantra R, Brown RJC, Milton MJT, Gohil DD (2008) A practical method to fabricate gold substrates for surface-enhanced Raman spectroscopy. Appl Spectrosc Vol. 62:992-1000
21. Yang C, Xie YT, Yuen MMF, Xiong XM, Wong CP (2010) A facile chemical approach for preparing a SERS active silver substrate. Phys Chem Chem Phys 12(43):14459-14461
22. Semin DJ, Rowlen KL (1994) Influence of vapor deposition parameters on SERS active Ag film morphology and optical properties. Anal Chem 66:4324-4331
23. Roark SE, Rowlen KL (1994) Thin Ag films: influence of substrate and postdeposition treatment on morphology and optical properties. Anal Chem 66:261-270
24. Haynes CL, Van Duyne RP (2001) Nanosphere lithography: a versatile nanofabrication tool for studies of size-dependent nanoparticle optics. J Phys Chem B 105:5599-5611
25. Haes AJ, Chang L, Klein WL, Van Duyne RP (2005) Detection of a biomarker for Alzheimer’s disease from synthetic and clinical samples using a nanoscale optical biosensor. J Am Chem Soc 127(7):2264-2271
26. Stosch R, Yaghobian F, Weimann T, Brown RJC, Milton MJT, Guttler B (2011) Lithographical gap-size engineered nanoarrays for surface-enhanced Raman probing of biomarkers. Nanotechnology 22(10):105303
27. Abu Hatab NA, Oran JM, Sepaniak MJ (2008) Surface-enhanced Raman spectroscopy substrates created via electron beam lithography and nanotransfer printing. ACS Nano 2(2):377-385
28. Cialla D, Huebner U, Schneidewind H, Moeller R, Popp J (2008) Probing innovative microfabricated substrates for their reproducible SERS activity. ChemPhysChem 9(5):758-762
29. Porter Jr LA, Choi HC, Schmeltzer JM, Ribbe AE, Elliott LCC, Buriak JM (2002) Electroless nanoparticle film deposition compatible with photolithography, microcontact printing, and dip-pen nanolithography patterning technologies. NanoLetters 2(12):1369-1372
30. Dieringer JA, McFarland AD, Shah NC, Stuart DA, Whitney AV, Yonzon CR, Young MA, Zhang XY, Van Duyne RP (2006) Surface enhanced Raman spectroscopy: new materials, concepts, characterization tools, and applications. Faraday Discussions 132:9-26
31. Baia L, Baia M, Popp J, Astilean S (2006) Gold films deposited over regular arrays of polystyrene nanospheres as highly effective SERS substrates from visible to NIR. J Phys Chem B 110(47):23982-23986
32. Haynes CL, Van Duyne RP (2003) Plasmon-sampled surface-enhanced Raman excitation spectroscopy. J Phys Chem B 107:7426-7433
33. Cialla D, März A, Böhme R, Theil F, Weber K, Schmitt M, Popp J (2012) Surface-enhanced Raman spectroscopy (SERS): progress and trends. Anal Bioanal Chem 403:27-54
34. Mohapatra S, Siddhanta S, Kumar DR, Narayana C, Maji TK (2010) Facile and green synthesis of SERS active and ferromagnetic silver nanorods. Eur J Inorg Chem 31:4969-4974
35. Smitha SL, GopchandranKG, Ravindran TR, Prasad VS (2011) Gold nanorods with finely tunable longitudinal surface plasmon resonance as SERS substrates. Nanotechnology 22:265705
36. Rycenga M, Camargo PHC, Li W, Moran CH, Xia Y, (2010) Understanding the SERS effects of single silver nanoparticles and their dimers, one at a time. J Phys Chem Lett 1:696-703
37. Sun Y, Xia Y (2002) Shape-controlled synthesis of gold and silver nanoparticles. Science 298:2176-2179
38. Rycenga M, Kim MH, Camargo PHC, Cobley C, Li Z-Y, Xia Y (2009) Surface-enhanced Raman scattering: comparison of three different molecules on single-crystal nanocubes and nanospheres of silver. J Phys Chem A 113:3932-3939
39. Eguchi M, Mitsui D, Wu H-L, Sato R, Teranishi T (2012) Simple reductant concentrationdependent shape control of polyhedral gold nanoparticles and their plasmonic properties. Langmuir 28(24):9021-9026
40. Khoury CG, Vo-Dinh T (2008) Gold nanostars for surface-enhanced Raman scattering:synthesis, characterization and optimization. J PhysChem C 112(48):18849-18859
41. Esenturk EN, Walker ARH (2009) Surface-enhanced Raman scattering spectroscopy via gold nanostars. J Raman Spectrosc 40(1):86-91
42. Rodriguez-Lorenzo L, Alvarez-Puebla RA, Garcia J, de Abajo F, Liz-Marzan LM (2010) Surface enhanced Raman scattering using star-shaped gold colloidal nanoparticles. J Phys Chem C 114(16):7336-7340
43. Kim JH, Kang T, Yoo SM, Lee SY, Kim B, Choi YK (2009) A well-ordered flower-like gold nanostructure for integrated sensors via surface-enhanced Raman scattering. Nanotechnology 20(23):235302
44. Gellner M, Kustner B, Schlucker S (2009) Optical properties and SERS efficiency of tunable gold/silver nanoshells. Vib Spectrosc 50:43-47
45. Oldenberg SJ, Averitt RD, Westcott SL, Halas NJ (1998) Nanoengineering of Optical Resonances. Chem Phys Lett 288:243-247
46. Alvarez-Puebla RA, Ross DJ, Nazri GA, Aroca RF (2005) Surface-enhanced Raman scattering on nanoshells with tunable surface plasmon resonance. Langmuir 21:10504-10508
47. Talley CE, Jackson JB, Oubre C, Grady NK, Hollars CW, Lane SM, Huser TR (2005) Surface- enhanced Raman scattering from individual Au nanoparticles and nanoparticle dimer substrates. Nano Lett 5:1569-1574
48. Jackson JB, Halas NJ (2004) Surface-enhanced Raman scattering on tunable plasmonic nanoparticle substrates. Proc Natl Acad Sci USA 101:17930-17935
49. Ochsenkuhn MA, Jess PRT, Stoquert H, Dholakia K, Campbell CJ, (2009) Nanoshells for surface-enhanced Raman spectroscopy in eukaryotic cells: cellular response and sensor development. ACS Nano 3(11):3613-3621
50. Lal S, Grady NK, Goodrich GP, Halas NJ (2006) Profiling the near field of a plasmonic nanoparticle with Raman-based molecular rulers. Nano Lett 6:2338-2343
51. Gellner M, Küstner B, Schlücker S (2009) Optical properties and SERS efficiency of tunable gold/silver nanoshells. Vibr Spectr 50:43-47
52. Li JF, Huang YF, Ding Y, Yang ZL, Li SB, Zhou XS, Fan FR, Zhang W, Zhou ZY, Wu DY, Ren B, Wang ZL, Tian ZQ (2010) Shell-isolated nanoparticle-enhanced Raman spectroscopy. Nature 64(7287):392-395
53. Anema JR, Li JF, Yang ZL, Ren B, Tian ZQ (2011) Shell-isolated nanoparticle-enhanced Raman spectroscopy: expanding the versatility of surface-enhanced Raman scattering. Annu Rev Anal Chem 4:129-150
54. Kustner B, Gellner M, Schutz M, Schoppler F, Marx A, Strobel P, Adam P, Schmuck C, Schlucker S (2009) SERS labels for red laser excitation: silica-encapsulated SAMs on tunable gold/silver nanoshells. Angew Chem Int Ed 48:1950-1953
55. Mulvaney SP, Musick M D, Keating CD. Natan MJ (2003) Glass-coated, analyte-tagged nanoparticles: a new tagging system based on detection with surface-enhanced Raman scattering. Langmuir 19:4784-4790
56. Merican Z, Schiller TL, Hawker CJ, Fredericks PM, Blakey I (2007) Self-assembly and encoding of polymer-stabilized gold nanoparticles with surface-enhanced Raman reporter molecules. Langmuir 23:10539-10545
57. Moskovits M (2005) Surface-enhanced Raman spectroscopy: a brief retrospective. J Raman Spectrosc 36:485-496
58. Halas NJ, Lal S, Chang WS, Link S, Nordlander P (2011) Plasmons in strongly coupled metallic nanostructures. Chem Rev 111:3913-3939
59. Camden JP, Dieringer JA, Wang Y, Masiello DJ, Marks LD, Schatz GC, Van Duyne RP (2008) Probing the structure of single-molecule surface-enhanced Raman scattering hot spots. J Am Chem Soc 130:12616-12617
60. Rycenga M, Camargo PHC, Li W, Moran CH, Xia Y (2010) Understanding the SERS effects of single silver nanoparticles and their dimers, one at a time. J Phys Chem Lett 1:696-703
61. Wustholz KL, Henry AI, McMahon JM, Freeman RG, Valley N, Piotti ME, Natan MJ, Schatz GC, Van Duyne RP (2010) Structure-activity relationships in gold nanoparticle dimers and trimers for surface-enhanced Raman spectroscopy. J Am Chem Soc 132:10903-10910
62. Stockle RM, Suh YD, Deckert V, Zenobi R (2000) Nanoscale chemical analysis by tip-enhanced Raman spectroscopy. Chem Phys Lett 318:131-136
63. Pettinger B, Picardi G, Schuster R, Ertl G (2003) Surface-enhanced and STM tip-enhanced Raman spectroscopy of CN ions at gold surfaces. J Electroanal Chem 554:293-299
64. Picardi G, Nguyen Q, Schreiber J, Ossikovski R (2007) Comparative study of atomic force mode and tunneling mode tip-enhanced Raman spectroscopy. Eur Phys J Appl Phys 40:197-201
65. Zhang W, Yeo BS, Schmid T, Zenobi R (2007) Single-molecule tip-enhanced Raman spectroscopy with silver tips. J Phys Chem C 111:1733-1738
66. Sonntag MD, Klingsporn JM, Garibay LK, Roberts JM, Dieringer JA, Seideman T, Scheidt KA, Jensen L, Schatz GC, Van Duyne RP (2012) Single-molecule tip-enhanced Raman spectroscopy. J Phys Chem C 116:478-483
67. Yeo BS, Stadler J, Schmid T, Zenobi R, Zhang W (2009) Tip-enhanced Raman spectroscopy- its status, challenges and future directions. Chem Phys Lett 472:1-13
68. Bailo E, Deckert V (2008) Tip-enhanced Raman scattering. Chem Soc Rev 37:921-930
69. Deckert-Gaudig T, Deckert V (2010) Tip-enhanced Raman scattering (TERS) and highresolution bio nano-analysis-a comparison. Phys Chem Chem Phys 12:12040-12049
70. Cotton TM (1988) The application of surface-enhanced Raman scattering to biochemical systems. In: Clark RJH, Hester RE (eds) Spectroscopy of surfaces. Advances in Spectroscopy, vol 16. Wiley, New York, pp 91-153
71. Aliaga AE, Osorio-Roman I, Leyton P, Garrido C, Carcamo J, Caniulef C, Celis F, Díaz GF, Clavijo E, Gomez-Jeria JS, Campos-Vallette MM (2009) Surface-enhanced Raman scattering study of L-tryptophan. J Raman Spectrosc 40:164-169
72. Aliaga AE, Osorio-Roman I, Garrido C, Leyton P, Carcamo J, Clavijo E, Gomez-Jeria JS, Diaz FG, Campos-Vallette MM (2009) Surface enhanced Raman scattering study of L-lysine. Vib Spectrosc 50(1):131-135
73. Yaffe NR, Blanch EW (2008) Effects and anomalies that can occur in SERS spectra of biological molecules when using a wide range of aggregating agents for hydroxylaminereduced and citrate-reduced silver colloids. Vibr Spectrosc 48:196-201
74. Suh JS, Moskovits M (1986) Surface-enhanced Raman spectroscopy of amino acids and nucleotide bases adsorbed on silver. J Am Chem Soc 108:4711-4718
75. Lee HI, Suh SW, Kim MS (1988) Raman spectroscopy of L-tryptophan-containing peptides adsorbed on a silver surface. J Raman Spectrosc 19:491-495
76. Vidugiris GJA, Gudavicius AV, Razumas VJ, Kulys JJ (1989) Structure-potential dependence of adsorbed enzymes and amino acids revealed by the surface enhanced Raman effect. Eur Biophys J 17:19-23
77. Stewart S, Fredericks PM (1999) Surface-enhanced Raman spectroscopy of amino acids adsorbed on an electrochemically prepared silver surface. Spectrochim Acta Part A 55:1641-1660
78. Podstawka E, Ozaki Y, Proniewicz L (2004) Part I: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides adsorbed on colloidal silver. Appl Spectrosc 58:570-580
79. Podstawka E, Ozaki Y, Proniewicz L (2005) Part III: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides deposited onto colloidal Gold Surface. Appl Spectrosc 59:1516-1526
80. Guerrero AR, Aroca RF (2012) Surface-enhanced Raman scattering of hydroxyproline. J Raman Spectrosc 43:478-481
81. Brolo AG, Germain P, Hager G (2002) Investigation of the adsorption of L-Cysteine on a polycrystalline silver electrode by surface-enhanced Raman scattering (SERS) and Surface-Enhanced Second Harmonic Generation (SESHG). J Phys Chem B 106:5982-5987
82. Lee HI, Kim MS, Suh SW (1991) Raman spectroscopy of sulphur-containing amino acids and their derivatives adsorbed on silver. J Raman Spectrosc 22:91-96
83. Graff M, Bukowska J (2005) Adsorption of enantiomeric and racemic cysteine on a silver electrode-SERS sensitivity to chirality of adsorbed molecules. J Phys Chem B 109:9567-9574
84. Lee HI, Kim MS, Suh SW (1991) Raman spectroscopy of sulphur-containing amino acids and their derivatives adsorbed on silver. J Raman Spectrosc 22:91-96
85. Kühnle A, Linderoth TR, Hammer B, Besenbacher F (2002) Chiral recognition in dimerization of adsorbed cysteine observed by scanning tunneling microscopy. Nature 415:891-893
86. Graff M, Bukowska J (2010) Enantiomeric recognition of phenylalanine by self-assembled monolayers of cysteine: surface-enhanced Raman scattering evidence. Vibr Spectr 52:103-107
87. Graff M, Bukowska J (2011) Surface-enhanced Raman Scattering (SERS) spectroscopy of enantiomeric and racemic methionine on a silver electrode-evidence for chiral discrimination in interactions between adsorbed molecules. Chem Phys Lett 509:58-61
88. Deckert-Gaudig T, Deckert V (2009) Ultraflat transparent gold nanoplates-ideal substrates for tip-enhanced Raman scattering experiments. Small 5(4):432-436
89. Deckert-Gaudig T, Deckert V (2009) Tip-enhanced Raman scattering studies of histidine on novel silver substrates. J Raman Spectrosc 40:1446-1451
90. Stewart S, Fredericks PM (1999) Surface-enhanced Raman spectroscopy of peptides and proteins adsorbed on an electrochemically prepared silver surface. Spectrochim Acta Part A 55:1615-1640
91. Wei F, Zhang D, Halas NJ, Hartgerink JD (2008) Aromatic amino acids providing characteristic motifs in the Raman and SERS spectroscopy of peptides. J Phys Chem B 112:9158-9164
92. Herne TM, Ahern A, Garrell RL (1991) Surface-enhanced Raman spectroscopy of peptides:preferential N-terminal adsorption on colloidal silver. J Am Chem Soc 113:846-854
93. Podstawka E, Ozaki Y (2008) Bombesin modified 6-14 C-terminal fragments adsorption on silver surfaces: influence of a surface substrate. Biopolymers 89:941-950
94. Podstawka E, Niaura G, Proniewicz LM (2010) Potential-dependent studies on the interaction between phenylalanine-substituted bombesin fragments and roughened Ag, Au, and Cu electrode surfaces. J Phys Chem B 114:1010-1029
95. Podstawka-Proniewicz E, Kudelski A, Younkyoo Kim Y, Proniewicz L (2012) Adsorption of neurotensin-family peptides on SERS-active Ag substrate. J Raman Spectrosc 43:1196-1203
96. Podstawka-Proniewicz E, Andrzejak M, Kafarski P, Kim Y, Proniewicz LM (2011) Vibrational characterization of L-valine phosphonate dipeptides: FT-IR, FT-RS, and SERS spectroscopy studies and DFT calculations. J Raman Spectrosc 42(5):958-979
97. Małek K, Królikowska A and Bukowska J (2012) Comparative studies on IR, Raman, and Surface Enhanced Raman scattering spectroscopy of dipeptides containing ΔAla and ΔPhe. J Phys Chem B 116:1414-1425
98. Keating CD, Kovaleski KM, Natan MJ (1998) Protein: colloid conjugates for surface enhanced Raman scattering: stability and control of protein orientation. J Phys Chem B 102(45):9404-9413
99. Pavel I, McCarney E, Elkhaled A, Morrill A, Plaxco K, Moskovits M (2008) Label-free SERS detection of small proteins modified to act as bifunctional linkers. J Phys Chem C 112:4880-4883
100. Drachev VP, Nashine VC, Thoreson MD, Ben-Amotz D, Davisson VJ, Shalaev VM (2005) Adaptive silver films for detection of antibody-antigen binding. Langmuir 21:8368-8373
101. Aroca R (2006) Surface-enhanced vibrational spectroscopy. John Wiley, Chichester, pp 91-96
102. Deckert-Gaudig T, Bailo E, Deckert V (2009) Tip-enhanced Raman scattering (TERS) of oxidised glutathione on an ultraflat gold nanoplate. Phys Chem Chem Phys 11:7360-7362
103. Love JC, Estroff LA, Kriebel JK, Nuzzo RG, Whitesides GM (2005) Self-assembled monolayers of thiolates on metals as a form of nanotechnology. Chem Rev 105:1103-1169
104. Moyano DF, Rotello VM, (2011) Nano Meets Biology: Structure and Function at the Nanoparticle Interface. Langmuir 27:10376-10385
105. Królikowska A, Bukowska J (2007) Self-assembled monolayers of mercaptosuccinic acid monolayers on silver and gold surfaces designed for protein binding. Part II: vibrational spectroscopy studies on cytochrome c immobilization. J Raman Spectrosc 38:943-949
106. Fedurco M (2000) Redox reactions of heme-containing metalloproteins:dynamic effects of self-assembled monolayers on thermodynamics and kinetics of cytochrome c electrontransfer reactions. Coord Chem Rev 209:263-331
107. Hobara D, Imabayashi Si, Kakiuchi T (2002) Preferential adsorption of horse heart cytochrome c on nanometer-scale domains of a phase-separated binary self-assembled monolayer of 3-mercaptopropionic acid and 1-hexadecanethiol on Au(111). Nano Lett 2:1021-1025
108. Dick LA, Haes AJ, Van Duyne RP (2000) Distance and orientation dependence of heterogeneous electron transfer: a surface-enhanced resonance Raman scattering study of cytochrome c bound to carboxylic acid terminated alkanethiols adsorbed on silver electrodes. J Phys Chem B 104:11752-11762
109. Bonifacio A, van der Sneppen L, Gooijer C, van der Zwan G (2004) Citrate-reduced silver hydrosol modified with ö-mercaptoalkanoic acids self-assembled monolayers as a substrate for surface-enhanced resonance Raman scattering. A study with cytochrome c. Langmuir 20:5858-5864
110. Królikowska A, Bukowska J (2010) Surface-enhanced resonance Raman spectroscopic characterization of cytochrome c immobilized on 2-mercaptoethanesulfonate monolayers on silver. J Raman Spectrosc 41:1621-1631
111. Murgida DH, Hildebrandt P (2004) Electron-transfer processes of cytochrome c at interfaces. New insights by surface-enhanced resonance Raman spectroscopy. Acc Chem Res 37:854-861
112. Grochol J, Dronov R, Lisdat F, Hildebrandt P, Murgida DH (2007) Electron transfer in SAM/Cytochrome/Polyelectrolyte hybrid systems on electrodes: a time-resolved surfaceenhanced resonance Raman study. Langmuir 23:11289-11294
113. Hildebrandt P, Stockburger (1986) Surface-enhanced resonance Raman spectroscopy of cytochrome c at room and low temperatures. J Phys Chem 90:6017-6024
114. Oellerich S, Wackerbarth H, Hildebrandt P (2002) Spectroscopic characterization of nonnative conformational states of cytochrome c. J Phys Chem B 106:6566-6580
115. Macdonald IDG, Smith WE (1996) Orientation of cytochrome c adsorbed on a citrate-reduced silver colloid surface. Langmuir 12:706-713
116. Murgida DH, Hildebrandt P (2001) Heterogenous electron transfer of cytochrome c on coated silver electrodes. Electric field effects on structure and redox potential. J Phys Chem B 105:1578-1586
117. Kranich A., Ly HK, Hildebrandt P, Murgida DH (2008) Direct observation of the gating step in protein electron transfer: electric-field-controlled protein dynamics. J Am Chem Soc 130:9844-9848
118. Yeo BS, Madler S, Schmid T, Zhang W, Zenobi R (2008) Tip-enhanced Raman spectroscopy can see more: the case of cytochrome c. J Phys Chem C 112:4867-4873
119. Larmour IA, Faulds K, Graham D (2010) The past, present and future of enzyme measurements using surface enhanced Raman spectroscopy. Chem Sci 1:151-160
120. Copeland RA, Fodor SPA, Spiro TG (1984) Surface-enhanced Raman spectra of an active flavo enzyme: glucose oxidase and riboflavin binding protein on silver particles. J Am Chem Soc 106:3872-3874
121. Broderick JB, Natan MJ, O’Halloran TV, Van Duyne RP (1993) Evidence for retention of biological activity of a non-heme iron enzyme adsorbed on a silver colloid: a surface-enhanced resonance Raman scattering study. Biochemistry 32:13771-13776
122. Wu ZS,. Zhou GZ, Jiang JH, Shen GL, Yu RQ (2006) Gold colloid-bienzyme conjugates for glucose detection utilizing surface-enhanced Raman scattering. Talanta 70:533-539
123. Dou X, Takama T, Yamaguchi Y, Yamamoto H, Ozaki Y (1997) Enzyme Immunoassay Utilizing Surface-Enhanced Raman Scattering of the Enzyme Reaction Product. Anal Chem 69:1492-1495
124. Stevenson R, Ingram A, Leung H, McMillan DC, Graham D (2009) Quantitative SERRS immunoassay for detection of human PSA. Analyst 134:842-844
125. Ruan CM, Wang W, Gu BH, (2006) Detection of alkaline phosphatase using surface-enhanced Raman spectroscopy. Anal Chem 78:3379-3384
126. Barhoumi A, Zhang D, Tam F., Halas NJ (2008) Surface-enhanced Raman spectroscopy of DNA. J Am Chem Soc 130:5523-5529
127. Shafer-Peltier KE, Haynes CL, Glucksberg MR, Van Duyne RP (2003) Towards a glucose biosensor based on surface-enhanced Raman scattering. J Am Chem Soc 125:588-593
128. Yonzon CR, Haynes CL, Zhang XY, Walsh JT, Van Duyne RP (2004) A glucose biosensor based on surface-enhanced Raman scattering: improved partition layer, temporal stability, reversibility, and resistance to serum protein interference. Anal Chem 76:78-85
129. Lyandres O, Shah NC, Yonzon CR, Walsh JT, Glucksberg MR, Van Duyne RP (2005) Realtime glucose sensing by surface-enhanced Raman spectroscopy in bovine plasma facilitated by a mixed decanethiol/mercaptohexanol partition layer. Anal Chem 77:6134-6139
130. Stuart DA, Yonzon CR, Zhang X, Lyandres O, Shah NC, Glucksberg MR, Walsh JT, Van Duyne RP (2005) Glucose sensing using near-infrared surface-enhanced Raman spectroscopy:gold surfaces, 10-day stability, and improved accuracy. Anal Chem 77:4013-4019
131. Zhang XY, Young MA, Lyandres O, Van Duyne RP (2005) Rapid detection of an anthrax biomarker by surface-enhanced Raman spectroscopy. J Am Chem Soc 127:4484-4489
132. Cheng H-W, Chen Y-Y, Lin X-X, Huan S-Y, Wu H-L, Shen G-L, Yu R-Q (2011) Surfaceenhanced Raman spectroscopic detection of Bacillus subtilis spores using gold nanoparticle based substrates. Anal Chim Acta 707:155-163
133. Li M, Zhang J, Suri S, Sooter LJ, Ma D, Wu N (2012) Detection of adenosine triphosphate with an aptamer biosensor based on surface-enhanced Raman scattering. Anal Chem 84:2837-2842
134. Braun G, Lee SJ, Dante M, Nguyen T-Q, Moskovits M, Reich N (2007) Surface-enhanced Raman spectroscopy for DNA detection by nanoparticle assembly onto smooth metal films. J Am Chem Soc 129:6378-6379
135. Cao YC, Jin R, Mirkin CA (2002) Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. Science 297:1536-1540
136. Stokes RJ, Macaskill A, Dougan JA, Hargreaves PG, Stanford HM, Smith WE, Faulds K, Graham D (2007) Highly sensitive detection of dye-labelled DNA using nanostructured gold surfaces. Chem Commun 27:2811-2813
137. Faulds K, McKenzie F, Smith WE, Graham D (2007) Quantitative simultaneous multianalyte detection of DNA by dual-wavelength surface-enhanced resonance Raman scattering. Angew Chem Int Ed 46:1829-1831
138. Driskell JD, Kwarta KM, Lipert RJ, Porter MD (2005) Low-level detection of viral pathogens by a surface-enhanced Raman scattering based immunoassay. Anal Chem 77:6147-6154
139. Xu S, Ji X, Xu W, Li X, Wang L, Bai Y, Zhao B, Ozaki Y (2004) Immunoassay using probe-labelling immunogold nanoparticles with silver staining enhancement via surfaceenhanced Raman scattering. Analyst 129:63-68
140. Yakes BJ, Lipert RJ, Bannantine JP, Porter MD (2008) Detection of mycobacterium avium subsp. paratuberculosis by a sonicate immunoassay based on surface-enhanced Raman scattering. Clin Vaccine Immunol 15:227-234
141. Wang G, Park HY, Lipert RJ (2009) Mixed monolayers on gold nanoparticle labels for multiplexed surface-enhanced Raman scattering based immunoassays. Anal Chem 81:9643-9650
142. Chourpa I, Lei FH, Dubois P, Manfaita M, Sockalingum GD (2008) Intracellular applications of analytical SERS spectroscopy and multispectral imaging. Chem Soc Rev 37:993-1000
143. Xie W, Su L, Shen A, Materny A, Hu J (2011) Application of surface-enhanced Raman scattering in cell analysis. J Raman Spectrosc 42:1248-1254
144. Kneipp J, Kneipp H, Kneipp K (2008) SERS-a single-molecule and nanoscale tool for bioanalytics. Chem Soc Rev 37:1052-1060
145. Vitol EA, Orynbayeva Z, Friedman G, Gogotsi Y (2012) Nanoprobes for intracellular and single cell surface-enhanced Raman spectroscopy (SERS). J Raman Spectrosc 43:817-827
146. Nabiev IR, Morjani H, Manfait M (1991) Selective analysis of antitumor drug interaction with living cancer cells as probed with surface-enhanced Raman spectroscopy Eur Biophys J 19:311-316
147. Kneipp J, Kneipp H, McLaughlin M, Brown D, Kneipp K (2006) In Vivo Molecular Probing of Cellular Compartments with Gold Nanoparticles and Nanoaggregates. Nano Letters. 6(10):2225-2231
148. Kneipp J, Kneipp H, Rajadurai A, Redmont RW, Kneipp K (2009) Optical probing and imaging of live cells using SERS labels. J Raman Spectrosc 40:1-5
149. Oyelere AK, Chen PC, Huang X, El-Sayed IH, El-Sayed MA (2007) Peptide-Conjugated Gold Nanorods for Nuclear Targeting. Bioconjugate Chem 18:1490-1497
150. Rodriguez-Lorenzo L, Krpetic Z, Barbosa S, Alvarez-Puebla RA, Liz-Marzan LM, Prior IA, Brust M (2011) Intracellular mapping with SERS-encoded gold stars. Integr Biol 3:922-926
151. Xie JP, Zhang QB, Lee JY (2008) The synthesis of SERS-active gold nanoflower tags for In Vivo applications. ACS Nano 2:2473-2480
152. Vitol EA, Orynbayeva Z, Bouchard MJ, Azizkhan-Clifford J, Friedman G, Gogotsi Y (2009) In Situ intracellular spectroscopy with surface enhanced Raman spectroscopy (SERS)-enabled nanopipettes. ACS Nano 3(11):3529-3536
153. Kneipp K, Haka AS, Kneipp H, Badizadegan K, Yoshizawa N, Boone C, Shafer-Peltier K, Motz JT, Dasari RR, Feld MS (2002) Surface-enhanced Raman spectroscopy in single living cells using gold nanoparticles. Appl Spectrosc 56:150-154
154. Jarvis RM, Law N, Shadi LT, O’Brien P, Lloyd JR, Goodacre R (2008) Surface-enhanced Raman scattering from intracellular and extracellular bacterial locations. Anal Chem 80:6741-6746
155. Efrima S, Zeiri L (2009) Understanding SERS of bacteria. J Raman Spectrosc 40:277-288
156. Gessner R, Winter C, Rosch P, Schmitt M, Petry R, Kiefer W, Lankers M, Popp J (2004) Identification of Biotic and Abiotic Particles by Using a Combination of Optical Tweezers and In Situ Raman Spectroscopy. ChemPhysChem 5:1159-1170
157. Scaffidi JP, Gregas MK, Seewaldt V, Vo-Dinh T (2009) SERS-based plasmonic nanobiosensing in single living cells. Anal Bioanal Chem 393:1135-1141
158. Bohme R, Richter M, Cialla D, Rosch P, Deckert V, Popp J (2009) Towards a specific characterization of components on a cell surface-combined TERS-investigations of lipids and human cells. J Raman Spectrosc 40:1452-1457
159. Cialla D, Deckert-Gaudig T, Budich C, Laue M, Moller R, Naumann D, Deckert V, Popp J (2009) Raman to the limit: tip-enhanced Raman spectroscopic investigations of a single tobacco mosaic virus. J Raman Spectrosc 40:240-243
160. Budich C, Neugebauer U, Popp J, Deckert V (2008) Cell Wall investigations utilizing tipenhanced Raman scattering. J Microsc 229:533-539
161. Kozitskaya S, Deckert V, Schmitt M, Popp J (2007) Towards a detailed understanding of bacterial metabolism-spectroscopic characterization of Staphylococcus Epidermidis. ChemPhysChem 8:124-137
162. Auchinvole CAR, Richardson P, McGuinnes C, Mallikarjun V, Donaldson K, McNab H, Campbell CJ (2012) Monitoring intracellular redox potential changes using SERS nanosensors. ACS Nano 6(1):888-896
163. Kneipp J, Kneipp H, Wittig B, Kneipp K (2007) One- and two-photon excited optical pH probing for cells using surface-enhanced Raman and hyper-Raman nanosensors. Nano Lett 7:2819-2823
164. Talley CE, Jusinski L, Hollars CW, Lane SM, Huser T (2004) Intracellular pH sensors based on surface-enhanced Raman scattering. Anal Chem 76:7064-7068
165. Nowak-Lovato KL, Wilson BS, Rector KD (2010) SERS nanosensors that report pH of endocytic compartments during FcεRI transit. Anal Bioanal Chem 398:2019-2029
166. Kneipp J, Kneipp H, Wittig B, Kneipp K (2010) Following the dynamics of pH in endosomes of live cells with SERS nanosensors. J Phys Chem C 114:7421-7426
167. Zong S, Wang Z, Yang J, Cui Y (2011) Intracellular pH sensing using p-aminothiophenol functionalized gold nanorods with low toxicity. Anal Chem 83:4178-4183
168. Balint S, Rao S, Marro M, Miskovsky P, Petrov D (2011) Monitoring of local pH in photodynamic therapy-treated live cancer cells using surface-enhanced Raman scattering probes. J Raman Spectrosc 42:1215-1221
169. Bishnoi SW, Rozell CJ, Levin CS, Gheith MK, Johnson BR, Johnson DH, Halas NJ (2006) All-optical nanoscale pH meter. Nano Lett 6:1687-1692
170. Ando RA, Pieczonka NPW, Santos PS, Aroca RF (2009) Chromic materials for responsive surface-enhanced resonance Raman scattering systems: a nanometric pH sensor. Phys Chem Chem Phys 11:7505-7508
171. Qian X, Peng XH, Ansari DO, Yin-Goen Q, Chen GZ, Shin DM, Yang L, Young AN, Wang MD, Nie SM (2008) In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags. Nat Biotech 26:83-90
172. Lee S, Kim S, Choo J, Shin SY, Lee YH, Choi HY, Ha S, Kang KH, Oh CH (2007) Biological imaging of HEK293 cells expressing PLCç1 using surface-enhanced Raman microscopy. Anal Chem 79:916-922