The noncaloric sweetener rebaudioside a stimulates glucagon-like peptide 1 release and increases enteroendocrine cell numbers in 2-dimensional mouse organoids derived from different locations of the intestine

Journal of Nutrition

Volumn 146, Issue 12, 2016, Pages 2429-2435

  van der Wielen, Nikkie ^a,b   ten Klooster, Jean Paul ^c   Muckenschnabl, Susanne ^b   Pieters, Raymond ^c   Hendriks, Henk F J ^a   Witkamp, Renger F ^b   Meijerink, Jocelijn ^a  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF APPLIED SCIENCES UTRECHT   (Netherlands)

Author keywords

Duodenum; GLP 1; Glucagon like peptide 1; Gut hormone; Ileum; Jejunum; Minigut; Organoids; Peptide YY; Stevia

Indexed keywords

CHOLECYSTOKININ; CHROMOGRANIN A; GLUCAGON LIKE PEPTIDE 1; PEPTIDE YY; REBAUDIOSIDE A; SEROTONIN; SWEETENING AGENT; UNCLASSIFIED DRUG; KAURANE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL COUNT; CONTROLLED STUDY; CRYPT CELL; DUODENUM; ENTEROENDOCRINE CELL; GENE EXPRESSION; GOBLET CELL; HORMONE RELEASE; ILEUM; IMMUNOFLUORESCENCE; INTESTINE CELL; INTESTINE CRYPT; JEJUNUM; MALE; MOUSE; NONHUMAN; PROTEIN SECRETION; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; CYTOPLASM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; SMALL INTESTINE; TISSUE CULTURE TECHNIQUE;

ANIMALS; CELL PROLIFERATION; DITERPENES, KAURANE; ENTEROENDOCRINE CELLS; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; INTESTINE, SMALL; MICE; MICE, INBRED C57BL; ORGANOIDS; SWEETENING AGENTS; TISSUE CULTURE TECHNIQUES;

EID: 85007021597     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.116.232678     Document Type: Article

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