The Syk-NFAT-IL-2 pathway in dendritic cells is required for optimal sterile immunity elicited by alum adjuvants

Journal of Immunology

Volumn 198, Issue 1, 2017, Pages 196-204

  Khameneh, Hanif Javanmard ^a   Ho, Adrian W S ^a   Spreafico, Roberto ^a,b   Derks, Heidi ^a   Quek, Hazel Q Y ^a   Mortellaro, Alessandra ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM SALT; CALCIUM ION; CRYOPYRIN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2; PROTEIN KINASE SYK; TRANSCRIPTION FACTOR NFAT; URIC ACID; ALUMINUM POTASSIUM SULFATE; ALUMINUM SULFATE;

ACTIN POLYMERIZATION; ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CALCIUM MOBILIZATION; CD4+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME ACTIVATION; HUMORAL IMMUNITY; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NFATC TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION; SYK KINASE;

EID: 85007016477     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600420     Document Type: Article

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