Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 51, 2016, Pages 14805-14810

  Semenkovich, Nicholas P ^a   Planer, Joseph D ^a   Ahern, Philip P ^a   Griffin, Nicholas W ^a   Lin, Charles Y ^b   Gordon, Jeffrey I ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

ATAC seq; Enhancers of gut intraepithelial lymphocytes; Gnotobiotic mice; Gut microbiota immune cell interactions; Transcription factors

Indexed keywords

ALPHA4 INTEGRIN; AROMATIC HYDROCARBON RECEPTOR; CBL PROTEIN B; CHEMOKINE RECEPTOR CXCR4; FOCAL ADHESION KINASE 1; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 23 RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PROLACTIN RECEPTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; SPHINGOSINE 1 PHOSPHATE; STAT3 PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

ALPHA BETA LYMPHOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY FOR TRANSPOSASE ACCESSIBLE CHROMATIN WITH HIGH THROUGHPUT SEQUENCING; BACTERIAL COLONIZATION; BILE ACID METABOLISM; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA MODIFICATION; ENHANCER REGION; GAMMA DELTA T LYMPHOCYTE; HIGH THROUGHPUT SEQUENCING; IMMUNOSURVEILLANCE; INTESTINE CELL; INTESTINE FLORA; MALE; MICROBIAL COMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUCKLING ANIMAL; WEANING; ANIMAL; C57BL MOUSE; CELL LINEAGE; CHEMISTRY; CHROMATIN; CYTOLOGY; GERMFREE ANIMAL; INTESTINE; INTRAEPITHELIAL LYMPHOCYTE; METABOLISM; MICROBIOLOGY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; CHROMATIN; ENHANCER ELEMENTS, GENETIC; GASTROINTESTINAL MICROBIOME; GERM-FREE LIFE; INTESTINES; INTRAEPITHELIAL LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION;

EID: 85006930186     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1617793113     Document Type: Article

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