Reciprocal interactions between commensal bacteria and γδ intraepithelial lymphocytes during mucosal injury

Journal of Immunology

Volumn 182, Issue 5, 2009, Pages 3047-3054

  Ismail, Anisa S ^a   Behrendt, Cassie L ^a   Hooper, Lora V ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; MYELOID DIFFERENTIATION FACTOR 88; T LYMPHOCYTE RECEPTOR DELTA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL FLORA; CELL DAMAGE; CELL PROTECTION; COLON INJURY; COLON MUCOSA; COMMENSAL; COMMENSALISM; CONTROLLED STUDY; GAMMA DELTA INTRAEPITHELIAL LYMPHOCYTE; GENOME ANALYSIS; HOMEOSTASIS; HOST PATHOGEN INTERACTION; IMMUNOMODULATION; INTESTINE FLORA; INTESTINE MUCOSA; LYMPHOCYTE FUNCTION; MICROARRAY ANALYSIS; MICROFLORA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; T LYMPHOCYTE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL COMMUNICATION; COLON; DNA MICROARRAY; DRUG EFFECT; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; LYMPHOCYTE SUBPOPULATION; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PATHOLOGY;

ANIMALS; CELL COMMUNICATION; COLON; DEXTRAN SULFATE; EPITHELIAL CELLS; HOMEOSTASIS; INTESTINAL MUCOSA; LYMPHOCYTE SUBSETS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 64849089226     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802705     Document Type: Article

References (33)

1. Chen, Y., K. Chou, E. Fuchs, W. L. Havran, and R. Boismenu. 2002. Protection of the intestinal mucosa by intraepithelial γδ T cells. Proc. Natl. Acad. Sci. USA 99: 14338-14343.
2. Jameson, J., K. Ugarte, N. Chen, P. Yachi, E. Fuchs, R. Boismenu, and W. L. Havran. 2002. A role for skin γδ T cells in wound repair. Science 296: 747-749.
3. Komano, H., Y. Fujiura, M. Kawaguchi, S. Matsumoto, Y. Hashimoto, S. Obana, P. Mombaerts, S. Tonegawa, H. Yamamoto, S. Itohara, et al. 1995. Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells. Proc. Natl. Acad. Sci. USA 92: 6147-6151.
4. Hooper, L. V., M. H. Wong, A. Thelin, L. Hansson, P. G. Falk, and J. I. Gordon. 2001. Molecular analysis of commensal host-microbial relationships in the intestine. Science 291: 881-884.
5. Mysorekar, I. U., R. G. Lorenz, and J. I. Gordon. 2002. A gnotobiotic transgenic mouse model for studying interactions between small intestinal enterocytes and intraepithelial lymphocytes. J. Biol. Chem. 277: 37811-37819.
6. Cash, H. L., C. V. Whitham, C. L. Behrendt, and L. V. Hooper. 2006. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313: 1126-1130.
7. Yada, S., K. Kishihara, Y. Y. Kong, and K. Nomoto. 1998. Differential requirements of CD45 protein tyrosine phosphatase for cytolytic activities and intrathymic and extrathymic development of intestinal intraepithelial lymphocytes. J. Immunol. 161: 2208-2216.
8. Fahrer, A. M., Y. Konigshofer, E. M. Kerr, G. Ghandour, D. H. Mack, M. M. Davis, and Y. H. Chien. 2001. Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile. Proc. Natl. Acad. Sci. USA 98: 10261-10266.
9. + intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE). Immunity 15: 419-434.
10. Pull, S. L., J. M. Doherty, J. C. Mills, J. I. Gordon, and T. S. Stappenbeck. 2005. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc. Natl. Acad. Sci. USA 102: 99-104.
11. Beagley, K. W., K. Fujihashi, A. S. Lagoo, S. Lagoo-Deenadaylan, C. A. Black, A. M. Murray, A. T. Sharmanov, M. Yamamoto, J. R. McGhee, C. O. Elson, et al. 1995. Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine. J. Immunol. 154: 5611-5619.
12. Kuo, S., A. El Guindy, C. M. Panwala, P. M. Hagan, and V. Camerini. 2001. Differential appearance of T cell subsets in the large and small intestine of neonatal mice. Pediatr. Res. 49: 543-551.
13. Malago, J. J., J. F. Koninkx, and J. E. van Dijk. 2002. The heat shock response and cytoprotection of the intestinal epithelium. Cell Stress Chaperones 7: 191-199.
14. Ueland, J. M., J. Gwira, Z. X. Liu, and L. G. Cantley. 2004. The chemokine KC regulates HGF-stimulated epithelial cell morphogenesis. Am. J. Physiol. 286: F581-F589.
15. 1 integrin. Biochem. Biophys. Res. Commun. 294: 940-948.
16. Toth, B., M. Alexander, T. Daniel, I. H. Chaudry, W. J. Hubbard, and M. G. Schwacha. 2004. The role of γδ T cells in the regulation of neutrophilmediated tissue damage after thermal injury. J. Leukocyte Biol. 76: 545-552.
17. Li, Z., A. R. Burns, R. E. Rumbaut, and C. W. Smith. 2007. γδ T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion. Am. J. Pathol. 171: 838-845.
18. Boismenu, R., L. Feng, Y. Y. Xia, J. C. Chang, and W. L. Havran. 1996. Chemokine expression by intraepithelial γδ T cells: implications for the recruitment of inflammatory cells to damaged epithelia. J. Immunol. 157: 985-992.
19. Shahabuddin, S., R. Ji, P. Wang, E. Brailoiu, N. Dun, Y. Yang, M. O. Aksoy, and S. G. Kelsen. 2006. CXCR3 chemokine receptor-induced chemotaxis in human airway epithelial cells: role of p38 MAPK and PI3K signaling pathways. Am. J. Physiol. 291: C34-C39.
20. Kobayashi, Y. 2008. The role of chemokines in neutrophil biology. Front. Biosci. 13: 2400-2407.
21. Miller, L. S., E. M. Pietras, L. H. Uricchio, K. Hirano, S. Rao, H. Lin, R. M. O'Connell, Y. Iwakura, A. L. Cheung, G. Cheng, and R. L. Modlin. 2007. Inflammasome-mediated production of IL-1b is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol. 179: 6933-6942.
22. Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell 124: 783-801.
23. Rakoff-Nahoum, S., J. Paglino, F. Eslami-Varzaneh, S. Edberg, and R. Medzhitov. 2004. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 118: 229-241.
24. Iiyama, R., T. Kanai, K. Uraushihara, T. Ishikura, S. Makita, T. Totsuka, M. Yamazaki, T. Nakamura, T. Miyata, H. Yoshida, et al. 2003. Normal development of the gut-associated lymphoid tissue except Peyer's patch in MyD88-deficient mice. Scand. J. Immunol. 58: 620-627.
25. Balkovetz, D. F., and J. Katz. 2003. Bacterial invasion by a paracellular route: divide and conquer. Microbes Infect. 5: 613-619.
26. Poritz, L. S., K. I. Garver, C. Green, L. Fitzpatrick, F. Ruggiero, and W. A. Koltun. 2007. Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis. J. Surg. Res. 140: 12-19.
27. Itohara, S., P. Mombaerts, J. Lafaille, J. Iacomini, A. Nelson, A. R. Clarke, M. L. Hooper, A. Farr, and S. Tonegawa. 1993. T cell receptor δ gene mutant mice: independent generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell 72: 337-348.
28. Niess, J. H., S. Brand, X. Gu, L. Landsman, S. Jung, B. A. McCormick, J. M. Vyas, M. Boes, H. L. Ploegh, J. G. Fox, et al. 2005. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307: 254-258.
29. Macpherson, A. J., and T. Uhr. 2004. Compartmentalization of the mucosal immune responses to commensal intestinal bacteria. Ann. NY Acad. Sci. 1029: 36-43.
30. Mokuno, Y., T. Matsuguchi, M. Takano, H. Nishimura, J. Washizu, T. Ogawa, O. Takeuchi, S. Akira, Y. Nimura, and Y. Yoshikai. 2000. Expression of Toll-like receptor 2 on γδ T cells bearing invariant Vγ6/Vδ1 induced by Escherichia coli infection in mice. J. Immunol. 165: 931-940.
31. Berkes, J., V. K. Viswanathan, S. D. Savkovic, and G. Hecht. 2003. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut 52: 439-451.
32. Yu, Q., C. Tang, S. Xun, T. Yajima, K. Takeda, and Y. Yoshikai. 2006. MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8αα TCRαβ and TCRγδ intestinal intraepithelial lymphocytes. J. Immunol. 176: 6180-6185.
33. Jameson, J. M., G. Cauvi, L. L. Sharp, D. A. Witherden, and W. L. Havran. 2005. γδ T cell-induced hyaluronan production by epithelial cells regulates inflammation. J. Exp. Med. 201: 1269-1279.