Engineering an Affinity-Enhanced Peptide through Optimization of Cyclization Chemistry

Bioconjugate Chemistry

Volumn 27, Issue 12, 2016, Pages 2854-2862

  Ngambenjawong, Chayanon ^a   Pineda, Julio Marco B ^a   Pun, Suzie H ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; AMINO ACIDS; BINDING ENERGY; COPPER COMPOUNDS; COVALENT BONDS; CYCLIZATION; CYCLOADDITION; DISSOCIATION; MACROPHAGES; SULFUR COMPOUNDS;

ANTI-INFLAMMATORIES; BINDING ACTIVITIES; BRIDGE-FORMATION; CHEMICAL ENTITY; CYCLIZATION METHODS; CYCLIZATIONS; CYSTEINE-CONTAINING PEPTIDES; DISULPHIDE BRIDGE; OPTIMISATIONS; ORTHOGONALITY;

PEPTIDES;

AMIDE; AMIDE CYCLIZED M2 MACHOPHAGE BINDING PEPTIDE(RY) BIOTIN; ANTIINFLAMMATORY AGENT; BIOTIN DERIVATIVE; CYCLOPEPTIDE; DECAFLUOROBIPHENYL CYCLIZED M2 MACROPHAGE BINDING PEPTIDE BIOTIN; DECAFLUOROBIPHENYL SULFONE CYCLIZED M2 MACROPHAGE BINDING PEPTIDE(RY) BIOTIN; DISULFIDE; DISULFIDE CYCLIZED M2 MACROPHAGE BINDING PEPTIDE(RY) BIOTIN; MACROPHAGE BINDING PEPTIDE; TRIAZOLE CYCLIZED M2 MACHOPHAGE BINDING PEPTIDE(RY) BIOTIN; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; AZIDE; BIOTIN; PEPTIDE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APPARENT DISSOCIATION CONSTANT; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; COMPARATIVE STUDY; CONTROLLED STUDY; CYCLIZATION; CYCLOADDITION; DRUG SOLUBILITY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; MACROPHAGE; MACROPHAGE CULTURE; MOUSE; NONHUMAN; OXIDATION; PEPTIDE SYNTHESIS; PROTEIN DEGRADATION; ANIMAL; BLOOD; CHEMISTRY; METABOLISM; PROCEDURES; PROTEIN ENGINEERING; PROTEIN STABILITY; SYNTHESIS;

ANIMALS; AZIDES; BIOTIN; CHEMISTRY TECHNIQUES, SYNTHETIC; CIRCULAR DICHROISM; MACROPHAGES; MICE; PEPTIDES; PROTEIN ENGINEERING; PROTEIN STABILITY;

EID: 85006875514     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.6b00502     Document Type: Article

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