-
1
-
-
18244407799
-
Steps toward mapping the human vasculature by phage display
-
Arap, W., Kolonin, M. G., Trepel, M., Lahdenranta, J., Cardó-Vila, M., Giordano, R. J., et al. (2002). Steps toward mapping the human vasculature by phage display. Nat. Med. 8, 121-127. doi: 10.1038/nm0202-121
-
(2002)
Nat. Med
, vol.8
, pp. 121-127
-
-
Arap, W.1
Kolonin, M.G.2
Trepel, M.3
Lahdenranta, J.4
Cardó-Vila, M.5
Giordano, R.J.6
-
2
-
-
41949086504
-
Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues
-
Biron, E., Chatterjee, J., Ovadia, O., Langenegger, D., Brueggen, J., Hoyer, D., et al. (2008). Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues. Angew. Chem. Int. Ed. Engl. 47, 2595-2599. doi: 10.1002/anie.200705797
-
(2008)
Angew. Chem. Int. Ed. Engl
, vol.47
, pp. 2595-2599
-
-
Biron, E.1
Chatterjee, J.2
Ovadia, O.3
Langenegger, D.4
Brueggen, J.5
Hoyer, D.6
-
3
-
-
84878789554
-
Form and function in cyclic peptide natural products: a pharmacokinetic perspective
-
Bockus, A. T., McEwen, C. M., and Lokey, R. S. (2013). Form and function in cyclic peptide natural products: a pharmacokinetic perspective. Curr. Top. Med. Chem. 13, 821-836. doi: 10.2174/1568026611313070005
-
(2013)
Curr. Top. Med. Chem
, vol.13
, pp. 821-836
-
-
Bockus, A.T.1
McEwen, C.M.2
Lokey, R.S.3
-
4
-
-
60649083774
-
High-density peptide arrays
-
Breitling, F., Nesterov, A., Stadler, V., Felgenhauer, T., and Bischoff, F. R. (2009). High-density peptide arrays. Mol. Biosyst. 5, 224-234. doi: 10.1039/b819850k
-
(2009)
Mol. Biosyst
, vol.5
, pp. 224-234
-
-
Breitling, F.1
Nesterov, A.2
Stadler, V.3
Felgenhauer, T.4
Bischoff, F.R.5
-
5
-
-
84928700609
-
Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides
-
Chen, S., Gopalakrishnan, R., Schaer, T., Marger, F., Hovius, R., Bertrand, D., et al. (2014). Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nat. Chem. 6, 1009-1016. doi: 10.1038/nchem.2043
-
(2014)
Nat. Chem
, vol.6
, pp. 1009-1016
-
-
Chen, S.1
Gopalakrishnan, R.2
Schaer, T.3
Marger, F.4
Hovius, R.5
Bertrand, D.6
-
6
-
-
33645737723
-
Transderml protein delivery by a coadministered peptide identified via phage display
-
Chen, Y., Shen, Y., Guo, X., Zhang, C., Yang, W., Ma, M., et al. (2006). Transderml protein delivery by a coadministered peptide identified via phage display. Nat. Biotechnol. 24, 455-460. doi: 10.1038/nbt1193
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 455-460
-
-
Chen, Y.1
Shen, Y.2
Guo, X.3
Zhang, C.4
Yang, W.5
Ma, M.6
-
7
-
-
79958786544
-
Reprogramming the genetic code
-
Chin, J. W. (2011). Reprogramming the genetic code. EMBO J. 30, 2312-2324. doi: 10.1038/emboj.2011.160
-
(2011)
EMBO J
, vol.30
, pp. 2312-2324
-
-
Chin, J.W.1
-
8
-
-
84871394690
-
The future of peptide-based drugs
-
Craik, D. J., Fairlie, D. P., Liras, S., and Price, D. (2013). The future of peptide-based drugs. Chem. Biol. Drug Des. 81, 136-147. doi: 10.1111/cbdd.12055
-
(2013)
Chem. Biol. Drug Des
, vol.81
, pp. 136-147
-
-
Craik, D.J.1
Fairlie, D.P.2
Liras, S.3
Price, D.4
-
9
-
-
84934996624
-
Hydrocarbon stapled peptides as modulators of biological function
-
Cromm, P. M., Spiegel, J., and Grossmann, T. N. (2015). Hydrocarbon stapled peptides as modulators of biological function. ACS Chem. Biol. 10, 1362-1375. doi: 10.1021/cb501020r
-
(2015)
ACS Chem. Biol
, vol.10
, pp. 1362-1375
-
-
Cromm, P.M.1
Spiegel, J.2
Grossmann, T.N.3
-
10
-
-
34548814155
-
Protein engineering with bacterial display
-
Daugherty, P. S. (2007). Protein engineering with bacterial display. Curr. Opin. Struct. Biol. 17, 474-480. doi: 10.1016/j.sbi.2007.07.004
-
(2007)
Curr. Opin. Struct. Biol
, vol.17
, pp. 474-480
-
-
Daugherty, P.S.1
-
12
-
-
1642524195
-
Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier
-
Duerr, D. M., White, S. J., and Schluesener, H. J. (2004). Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier. J. Virol. Methods 116, 177-180. doi: 10.1016/j.jviromet.2003.11.012
-
(2004)
J. Virol. Methods
, vol.116
, pp. 177-180
-
-
Duerr, D.M.1
White, S.J.2
Schluesener, H.J.3
-
13
-
-
70350442846
-
An in vitro selection strategy for conferring protease resistance to ligand binding peptides
-
Eldridge, B., Cooley, R. N., Odegrip, R., McGregor, D. P., Fitzgerald, K. J., and Ullman, C. G. (2009). An in vitro selection strategy for conferring protease resistance to ligand binding peptides. Protein Eng. Des. Sel. 22, 691-698. doi: 10.1093/protein/gzp052
-
(2009)
Protein Eng. Des. Sel
, vol.22
, pp. 691-698
-
-
Eldridge, B.1
Cooley, R.N.2
Odegrip, R.3
McGregor, D.P.4
Fitzgerald, K.J.5
Ullman, C.G.6
-
14
-
-
0037117459
-
Filamentous phage as vector-mediated antibody delivery to the brain
-
Frenkel, D., and Solomon, B. (2002). Filamentous phage as vector-mediated antibody delivery to the brain. Proc. Natl. Acad. Sci. U.S.A. 99, 5675-5679. doi: 10.1073/pnas.072027199
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 5675-5679
-
-
Frenkel, D.1
Solomon, B.2
-
15
-
-
84939805312
-
Ribosomal synthesis of macrocyclic peptides in vitro and in vivo mediated by genetically encoded aminothiol unnatural amino acids
-
Frost, J. R., Jacob, N. T., Papa, L. J., Owens, A. E., and Fasan, R. (2015). Ribosomal synthesis of macrocyclic peptides in vitro and in vivo mediated by genetically encoded aminothiol unnatural amino acids. ACS Chem. Biol. 10, 1805-1816. doi: 10.1021/acschembio.5b00119
-
(2015)
ACS Chem. Biol
, vol.10
, pp. 1805-1816
-
-
Frost, J.R.1
Jacob, N.T.2
Papa, L.J.3
Owens, A.E.4
Fasan, R.5
-
16
-
-
34648832245
-
Yeast surface display for protein engineering and characterization
-
Gai, S. A., and Wittrup, K. D. (2007). Yeast surface display for protein engineering and characterization. Curr. Opin. Struct. Biol. 17, 467-473. doi: 10.1016/j.sbi.2007.08.012
-
(2007)
Curr. Opin. Struct. Biol
, vol.17
, pp. 467-473
-
-
Gai, S.A.1
Wittrup, K.D.2
-
17
-
-
0036976219
-
A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library
-
Gao, C., Mao, S., Ditzel, H. J., Farnaes, L., Wirsching, P., Lerner, R. A., et al. (2002). A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorg. Med. Chem. 10, 4057-4065. doi: 10.1016/S0968-0896(02)00340-1
-
(2002)
Bioorg. Med. Chem
, vol.10
, pp. 4057-4065
-
-
Gao, C.1
Mao, S.2
Ditzel, H.J.3
Farnaes, L.4
Wirsching, P.5
Lerner, R.A.6
-
18
-
-
0027404365
-
Screening chemically synthesized peptide libraries for biologically-relevant molecules
-
Geysen, H. M., and Mason, T. J. (1993). Screening chemically synthesized peptide libraries for biologically-relevant molecules. Bioorg. Med. Chem. Lett. 3, 397-404. doi: 10.1016/S0960-894X(01)80221-3
-
(1993)
Bioorg. Med. Chem. Lett
, vol.3
, pp. 397-404
-
-
Geysen, H.M.1
Mason, T.J.2
-
19
-
-
84892163643
-
Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties?
-
Giordanetto, F., and Kihlberg, J. (2014). Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties? J. Med. Chem. 57, 278-295. doi: 10.1021/jm400887j
-
(2014)
J. Med. Chem
, vol.57
, pp. 278-295
-
-
Giordanetto, F.1
Kihlberg, J.2
-
20
-
-
77950398570
-
From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway
-
Giordano, R. J., Cardó-Vila, M., Salameh, A., Anobom, C. D., Zeitlin, B. D., Hawke, D. H., et al. (2010). From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proc. Natl. Acad. Sci. U.S.A. 107, 5112-5117. doi: 10.1073/pnas.0915141107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 5112-5117
-
-
Giordano, R.J.1
Cardó-Vila, M.2
Salameh, A.3
Anobom, C.D.4
Zeitlin, B.D.5
Hawke, D.H.6
-
21
-
-
84903151161
-
One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase
-
Goto, Y., Ito, Y., Kato, Y., Tsunoda, S., and Suga, H. (2014). One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase. Chem. Biol. 21, 766-774. doi: 10.1016/j.chembiol.2014.04.008
-
(2014)
Chem. Biol
, vol.21
, pp. 766-774
-
-
Goto, Y.1
Ito, Y.2
Kato, Y.3
Tsunoda, S.4
Suga, H.5
-
22
-
-
79958158209
-
Flexizymes for genetic code reprogramming
-
Goto, Y., Katoh, T., and Suga, H. (2011). Flexizymes for genetic code reprogramming. Nat. Protoc. 6, 779-790. doi: 10.1038/nprot.2011.331
-
(2011)
Nat. Protoc
, vol.6
, pp. 779-790
-
-
Goto, Y.1
Katoh, T.2
Suga, H.3
-
23
-
-
84861322262
-
Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery
-
Gould, A., Ji, Y., Aboye, T. L., and Camarero, J. A. (2011). Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery. Curr. Pharm. Des. 17, 4294-4307. doi: 10.2174/138161211798999438
-
(2011)
Curr. Pharm. Des
, vol.17
, pp. 4294-4307
-
-
Gould, A.1
Ji, Y.2
Aboye, T.L.3
Camarero, J.A.4
-
24
-
-
34748922922
-
The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis
-
Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L., and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis. Int. J. Biochem. Cell Biol. 39, 2252-2264. doi: 10.1016/j.biocel.2007.06.016
-
(2007)
Int. J. Biochem. Cell Biol
, vol.39
, pp. 2252-2264
-
-
Greenwood, K.P.1
Daly, N.L.2
Brown, D.L.3
Stow, J.L.4
Craik, D.J.5
-
25
-
-
84889102141
-
Phage display as a technology delivering on the promise of peptide drug discovery
-
Hamzeh-Mivehroud, M., Alizadeh, A. A., Morris, M. B., Church, W. B., and Dastmalchi, S. (2013). Phage display as a technology delivering on the promise of peptide drug discovery. Drug Discov. Today 18, 1144-1157. doi: 10.1016/j.drudis.2013.09.001
-
(2013)
Drug Discov. Today
, vol.18
, pp. 1144-1157
-
-
Hamzeh-Mivehroud, M.1
Alizadeh, A.A.2
Morris, M.B.3
Church, W.B.4
Dastmalchi, S.5
-
26
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes, J., and Plückthun, A. (1997). In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. U.S.A. 94, 4937-4942.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Plückthun, A.2
-
27
-
-
43049128964
-
An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides
-
Hartman, M. C., Josephson, K., Lin, C. W., and Szostak, J. W. (2007). An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides. PLoS ONE 2:e972. doi: 10.1371/journal.pone.0000972
-
(2007)
PLoS ONE
, vol.2
-
-
Hartman, M.C.1
Josephson, K.2
Lin, C.W.3
Szostak, J.W.4
-
28
-
-
67650305952
-
Phage-encoded combinatorial chemical libraries based on bicyclic peptides
-
Heinis, C., Rutherford, T., Freund, S., and Winter, G. (2009). Phage-encoded combinatorial chemical libraries based on bicyclic peptides. Nat. Chem. Biol. 5, 502-507. doi: 10.1038/nchembio.184
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 502-507
-
-
Heinis, C.1
Rutherford, T.2
Freund, S.3
Winter, G.4
-
29
-
-
84862058523
-
In vitro selection of functional lantipeptides
-
Hofmann, F. T., Szostak, J. W., and Seebeck, F. P. (2012). In vitro selection of functional lantipeptides. J. Am. Chem. Soc. 134, 8038-8041. doi: 10.1021/ja302082d
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 8038-8041
-
-
Hofmann, F.T.1
Szostak, J.W.2
Seebeck, F.P.3
-
30
-
-
27144431943
-
Selecting and screening recombinant antibody libraries
-
Hoogenboom, H. R. (2005). Selecting and screening recombinant antibody libraries. Nat. Biotechnol. 23, 1105-1116. doi: 10.1038/nbt1126
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 1105-1116
-
-
Hoogenboom, H.R.1
-
31
-
-
84947865948
-
Recombinant expression and phenotypic screening of a bioactive cyclotide against alpha-synuclein-induced cytotoxicity in baker's yeast
-
Jagadish, K., Gould, A., Borra, R., Majumder, S., Mushtaq, Z., Shekhtman, A., et al. (2015). Recombinant expression and phenotypic screening of a bioactive cyclotide against alpha-synuclein-induced cytotoxicity in baker's yeast. Angew. Chem. Int. Ed. Engl. 54, 8390-8394. doi: 10.1002/anie.201501186
-
(2015)
Angew. Chem. Int. Ed. Engl
, vol.54
, pp. 8390-8394
-
-
Jagadish, K.1
Gould, A.2
Borra, R.3
Majumder, S.4
Mushtaq, Z.5
Shekhtman, A.6
-
32
-
-
0037108767
-
Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin
-
Jin, L., and Harrison, S. C. (2002). Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin. Proc. Natl. Acad. Sci. U.S.A. 99, 13522-13526. doi: 10.1073/pnas.212504399
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 13522-13526
-
-
Jin, L.1
Harrison, S.C.2
-
33
-
-
84883256420
-
Future directions for peptide therapeutics development
-
Kaspar, A. A., and Reichert, J. M. (2013). Future directions for peptide therapeutics development. Drug Discov. Today 18, 807-817. doi: 10.1016/j.drudis.2013.05.011
-
(2013)
Drug Discov. Today
, vol.18
, pp. 807-817
-
-
Kaspar, A.A.1
Reichert, J.M.2
-
35
-
-
0025054575
-
Reinvestigation of the conformation of cyclosporin A in chloroform
-
Kessler, H., Köck, M., Wein, T., and Gehrke, M. (1990). Reinvestigation of the conformation of cyclosporin A in chloroform. Helv. Chim. Acta 73, 1818-1832.
-
(1990)
Helv. Chim. Acta
, vol.73
, pp. 1818-1832
-
-
Kessler, H.1
Köck, M.2
Wein, T.3
Gehrke, M.4
-
36
-
-
84861649020
-
Discovery, biosynthesis, and engineering of lantipeptides
-
Knerr, P. J., and van der Donk, W. A. (2012). Discovery, biosynthesis, and engineering of lantipeptides. Annu. Rev. Biochem. 81, 479-505. doi: 10.1146/annurev-biochem-060110-113521
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 479-505
-
-
Knerr, P.J.1
van der Donk, W.A.2
-
37
-
-
0026476589
-
Conformation of cyclosporin A in polar solvents
-
Ko, S. Y., and Dalvit, C. (1992). Conformation of cyclosporin A in polar solvents. Int. J. Pept. Protein Res. 40, 380-382.
-
(1992)
Int. J. Pept. Protein Res
, vol.40
, pp. 380-382
-
-
Ko, S.Y.1
Dalvit, C.2
-
38
-
-
69249124948
-
Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models
-
Kritzer, J. A., Hamamichi, S., McCaffery, J. M., Santagata, S., Naumann, T. A., Caldwell, K. A., et al. (2009). Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models. Nat. Chem. Biol. 5, 655-663. doi: 10.1038/nchembio.193
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 655-663
-
-
Kritzer, J.A.1
Hamamichi, S.2
McCaffery, J.M.3
Santagata, S.4
Naumann, T.A.5
Caldwell, K.A.6
-
39
-
-
34447530923
-
Potential of phage-displayed peptide library technology to identify functional targeting peptides
-
Krumpe, L. R., and Mori, T. (2007). Potential of phage-displayed peptide library technology to identify functional targeting peptides. Expert Opin. Drug Discov. 2, 525. doi: 10.1517/17460441.2.4.525
-
(2007)
Expert Opin. Drug Discov
, vol.2
, pp. 525
-
-
Krumpe, L.R.1
Mori, T.2
-
40
-
-
0027472271
-
The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors
-
Lam, K. S., Hruby, V. J., Lebl, M., Knapp, R. J., Kazmierski, W. M., Hersh, E. M., et al. (1993). The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors. Bioorg. Med. Chem. Lett. 3, 419-424. doi: 10.1016/S0960-894X(01)80224-9
-
(1993)
Bioorg. Med. Chem. Lett
, vol.3
, pp. 419-424
-
-
Lam, K.S.1
Hruby, V.J.2
Lebl, M.3
Knapp, R.J.4
Kazmierski, W.M.5
Hersh, E.M.6
-
41
-
-
33645523763
-
Optimizing the affinity and specificity of proteins with molecular display
-
Levin, A. M., and Weiss, G. A. (2006). Optimizing the affinity and specificity of proteins with molecular display. Mol. Biosyst. 2, 49-57. doi: 10.1039/b511782h
-
(2006)
Mol. Biosyst
, vol.2
, pp. 49-57
-
-
Levin, A.M.1
Weiss, G.A.2
-
42
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (2001). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46, 3-26. doi: 10.1016/S0169-409X(96)00423-1
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
43
-
-
0021923153
-
The conformation of cyclosporin A in the crystal and in solution
-
Loosli, H. R., Kessler, H., Oschkinat, H., Weber, H. P., Petcher, T. J., and Widmer, A. (1985). The conformation of cyclosporin A in the crystal and in solution. Helv. Chim. Acta 68, 682-704.
-
(1985)
Helv. Chim. Acta
, vol.68
, pp. 682-704
-
-
Loosli, H.R.1
Kessler, H.2
Oschkinat, H.3
Weber, H.P.4
Petcher, T.J.5
Widmer, A.6
-
44
-
-
70350774297
-
A peptide-based erythropoietin-receptor agonist for pure red-cell aplasia
-
Macdougall, I. C., Rossert, J., Casadevall, N., Stead, R. B., Duliege, A. M., Froissart, M., et al. (2009). A peptide-based erythropoietin-receptor agonist for pure red-cell aplasia. N. Engl. J. Med. 361, 1848-1855. doi: 10.1056/NEJMoa074037
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1848-1855
-
-
Macdougall, I.C.1
Rossert, J.2
Casadevall, N.3
Stead, R.B.4
Duliege, A.M.5
Froissart, M.6
-
45
-
-
0028592703
-
An in vitro polysome display system for identifying ligands from very large peptide libraries
-
Mattheakis, L. C., Bhatt, R. R., and Dower, W. J. (1994). An in vitro polysome display system for identifying ligands from very large peptide libraries. Proc. Natl. Acad. Sci. U.S.A. 91, 9022-9026.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 9022-9026
-
-
Mattheakis, L.C.1
Bhatt, R.R.2
Dower, W.J.3
-
46
-
-
0027253452
-
M13 bacteriophage displaying disulfide-constrained microproteins
-
McLafferty, M. A., Kent, R. B., Ladner, R. C., and Markland, W. (1993). M13 bacteriophage displaying disulfide-constrained microproteins. Gene 128, 29-36.
-
(1993)
Gene
, vol.128
, pp. 29-36
-
-
McLafferty, M.A.1
Kent, R.B.2
Ladner, R.C.3
Markland, W.4
-
47
-
-
35648992450
-
Design of cyclic peptides that bind protein surfaces with antibody-like affinity
-
Millward, S. W., Fiacco, S., Austin, R. J., and Roberts, R. W. (2007). Design of cyclic peptides that bind protein surfaces with antibody-like affinity. ACS Chem. Biol. 2, 625-634. doi: 10.1021/cb7001126
-
(2007)
ACS Chem. Biol
, vol.2
, pp. 625-634
-
-
Millward, S.W.1
Fiacco, S.2
Austin, R.J.3
Roberts, R.W.4
-
48
-
-
26844495780
-
A general route for post-translational cyclization of mRNA display libraries
-
Millward, S. W., Takahashi, T. T., and Roberts, R. W. (2005). A general route for post-translational cyclization of mRNA display libraries. J. Am. Chem. Soc. 127, 14142-14143. doi: 10.1021/ja054373h
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 14142-14143
-
-
Millward, S.W.1
Takahashi, T.T.2
Roberts, R.W.3
-
49
-
-
0031559943
-
In vitro virus: bonding of mRNA bearing puromycin at the 3'-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro
-
Nemoto, N., Miyamoto-Sato, E., Husimi, Y., and Yanagawa, H. (1997). In vitro virus: bonding of mRNA bearing puromycin at the 3'-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro. FEBS Lett. 414, 405-408.
-
(1997)
FEBS Lett
, vol.414
, pp. 405-408
-
-
Nemoto, N.1
Miyamoto-Sato, E.2
Husimi, Y.3
Yanagawa, H.4
-
50
-
-
84865696005
-
beta-Hairpin protein epitope mimetic technology in drug discovery
-
Obrecht, D., C. E., Moehle, K., and Robinson, J. (2012). beta-Hairpin protein epitope mimetic technology in drug discovery. Drug Discov. Today Technol. 9, e1-e70. doi: 10.1016/j.ddtec.2011.07.006
-
(2012)
Drug Discov. Today Technol
, vol.9
, pp. e1-e70
-
-
Obrecht, D.C.E.1
Moehle, K.2
Robinson, J.3
-
51
-
-
1542297763
-
CIS display: in vitro selection of peptides from libraries of protein-DNA complexes
-
Odegrip, R., Coomber, D., Eldridge, B., Hederer, R., Kuhlman, P. A., Ullman, C., et al. (2004). CIS display: in vitro selection of peptides from libraries of protein-DNA complexes. Proc. Natl. Acad. Sci. U.S.A. 101, 2806-2810. doi: 10.1073/pnas.0400219101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 2806-2810
-
-
Odegrip, R.1
Coomber, D.2
Eldridge, B.3
Hederer, R.4
Kuhlman, P.A.5
Ullman, C.6
-
52
-
-
37149000703
-
Synthesis of polyester by means of genetic code reprogramming
-
Ohta, A., Murakami, H., Higashimura, E., and Suga, H. (2007). Synthesis of polyester by means of genetic code reprogramming. Chem. Biol. 14, 1315-1322. doi: 10.1016/j.chembiol.2007.10.015
-
(2007)
Chem. Biol
, vol.14
, pp. 1315-1322
-
-
Ohta, A.1
Murakami, H.2
Higashimura, E.3
Suga, H.4
-
53
-
-
35348892636
-
The flexizyme system: a highly flexible tRNA aminoacylation tool for the translation apparatus
-
Ohuchi, M., Murakami, H., and Suga, H. (2007). The flexizyme system: a highly flexible tRNA aminoacylation tool for the translation apparatus. Curr. Opin. Chem. Biol. 11, 537-542. doi: 10.1016/j.cbpa.2007.08.011
-
(2007)
Curr. Opin. Chem. Biol
, vol.11
, pp. 537-542
-
-
Ohuchi, M.1
Murakami, H.2
Suga, H.3
-
54
-
-
0026437442
-
Identification of novel peptide antagonists for GPIIb/IIIa from a conformationally constrained phage peptide library
-
O'Neil, K. T., Hoess, R. H., Jackson, S. A., Ramachandran, N. S., Mousa, S. A., and DeGrado, W. F. (1992). Identification of novel peptide antagonists for GPIIb/IIIa from a conformationally constrained phage peptide library. Proteins 14, 509-515. doi: 10.1002/prot.340140411
-
(1992)
Proteins
, vol.14
, pp. 509-515
-
-
O'Neil, K.T.1
Hoess, R.H.2
Jackson, S.A.3
Ramachandran, N.S.4
Mousa, S.A.5
DeGrado, W.F.6
-
55
-
-
84987608654
-
Current challenges in peptide-based drug discovery
-
Otvos, L. Jr., and Wade, J. D. (2014). Current challenges in peptide-based drug discovery. Front. Chem. 2:62. doi: 10.3389/fchem.2014.00062
-
(2014)
Front. Chem
, vol.2
, pp. 62
-
-
Otvos, L.1
Wade, J.D.2
-
56
-
-
84902176344
-
Selection-based discovery of druglike macrocyclic peptides
-
Passioura, T., Katoh, T., Goto, Y., and Suga, H. (2014). Selection-based discovery of druglike macrocyclic peptides. Annu. Rev. Biochem. 83, 727-752. doi: 10.1146/annurev-biochem-060713-035456
-
(2014)
Annu. Rev. Biochem
, vol.83
, pp. 727-752
-
-
Passioura, T.1
Katoh, T.2
Goto, Y.3
Suga, H.4
-
57
-
-
84875686346
-
Selection of a high-affinity WW domain against the extracellular region of VEGF receptor isoform-2 from a combinatorial library using CIS display
-
Patel, S., Mathonet, P., Jaulent, A. M., and Ullman, C. G. (2013). Selection of a high-affinity WW domain against the extracellular region of VEGF receptor isoform-2 from a combinatorial library using CIS display. Protein Eng. Des. Sel. 26, 307-315. doi: 10.1093/protein/gzt003
-
(2013)
Protein Eng. Des. Sel
, vol.26
, pp. 307-315
-
-
Patel, S.1
Mathonet, P.2
Jaulent, A.M.3
Ullman, C.G.4
-
58
-
-
24044543111
-
A network of orthogonal ribosome x mRNA pairs
-
Rackham, O., and Chin, J. W. (2005). A network of orthogonal ribosome x mRNA pairs. Nat. Chem. Biol. 1, 159-166. doi: 10.1038/nchembio719
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 159-166
-
-
Rackham, O.1
Chin, J.W.2
-
60
-
-
84555196330
-
Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers
-
Reid, P. C., Goto, Y., Katoh, T., and Suga, H. (2012). Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers. Methods Mol. Biol. 805, 335-348. doi: 10.1007/978-1-61779-379-0_19
-
(2012)
Methods Mol. Biol
, vol.805
, pp. 335-348
-
-
Reid, P.C.1
Goto, Y.2
Katoh, T.3
Suga, H.4
-
61
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proteins
-
Roberts, R. W., and Szostak, J. W. (1997). RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl. Acad. Sci. U.S.A. 94, 12297-12302.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
Szostak, J.W.2
-
62
-
-
57049086900
-
Epitope mapping of antibodies using bacterial surface display
-
Rockberg, J., Löfblom, J., Hjelm, B., Uhlén, M., and Ståhl, S. (2008). Epitope mapping of antibodies using bacterial surface display. Nat. Methods 5, 1039-1045. doi: 10.1038/nmeth.1272
-
(2008)
Nat. Methods
, vol.5
, pp. 1039-1045
-
-
Rockberg, J.1
Löfblom, J.2
Hjelm, B.3
Uhlén, M.4
Ståhl, S.5
-
63
-
-
84863434152
-
In vitro selection of highly modified cyclic peptides that act as tight binding inhibitors
-
Schlippe, Y. V., Hartman, M. C., Josephson, K., and Szostak, J. W. (2012). In vitro selection of highly modified cyclic peptides that act as tight binding inhibitors. J. Am. Chem. Soc. 134, 10469-10477. doi: 10.1021/ja301017y
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 10469-10477
-
-
Schlippe, Y.V.1
Hartman, M.C.2
Josephson, K.3
Szostak, J.W.4
-
64
-
-
79956079627
-
Artificial lantipeptides from in vitro translations
-
Seebeck, F. P., Ricardo, A., and Szostak, J. W. (2011). Artificial lantipeptides from in vitro translations. Chem. Commun. 47, 6141-6143. doi: 10.1039/c0cc05663d
-
(2011)
Chem. Commun
, vol.47
, pp. 6141-6143
-
-
Seebeck, F.P.1
Ricardo, A.2
Szostak, J.W.3
-
65
-
-
33751540859
-
Display technologies: application for the discovery of drug and gene delivery agents
-
Sergeeva, A., Kolonin, M. G., Molldrem, J. J., Pasqualini, R., and Arap, W. (2006). Display technologies: application for the discovery of drug and gene delivery agents. Adv. Drug Deliv. Rev. 58, 1622-1654. doi: 10.1016/j.addr.2006.09.018
-
(2006)
Adv. Drug Deliv. Rev
, vol.58
, pp. 1622-1654
-
-
Sergeeva, A.1
Kolonin, M.G.2
Molldrem, J.J.3
Pasqualini, R.4
Arap, W.5
-
66
-
-
0034904102
-
Cell-free translation reconstituted with purified components
-
Shimizu, Y., Inoue, A., Tomari, Y., Suzuki, T., Yokogawa, T., Nishikawa, K., et al. (2001). Cell-free translation reconstituted with purified components. Nat. Biotechnol. 19, 751-755. doi: 10.1038/90802
-
(2001)
Nat. Biotechnol
, vol.19
, pp. 751-755
-
-
Shimizu, Y.1
Inoue, A.2
Tomari, Y.3
Suzuki, T.4
Yokogawa, T.5
Nishikawa, K.6
-
67
-
-
23044504786
-
Protein synthesis by pure translation systems
-
Shimizu, Y., Kanamori, T., and Ueda, T. (2005). Protein synthesis by pure translation systems. Methods 36, 299-304. doi: 10.1016/j.ymeth.2005.04.006
-
(2005)
Methods
, vol.36
, pp. 299-304
-
-
Shimizu, Y.1
Kanamori, T.2
Ueda, T.3
-
68
-
-
0033731476
-
Phage display for selection of novel binding peptides
-
Sidhu, S. S., Lowman, H. B., Cunningham, B. C., and Wells, J. A. (2000). Phage display for selection of novel binding peptides. Methods Enzymol. 328, 333-363.
-
(2000)
Methods Enzymol
, vol.328
, pp. 333-363
-
-
Sidhu, S.S.1
Lowman, H.B.2
Cunningham, B.C.3
Wells, J.A.4
-
70
-
-
43249113921
-
Ribosomal synthesis of N-methyl peptides
-
Subtelny, A. O., Hartman, M. C., and Szostak, J. W. (2008). Ribosomal synthesis of N-methyl peptides. J. Am. Chem. Soc. 130, 6131-6136. doi: 10.1021/ja710016v
-
(2008)
J. Am. Chem. Soc
, vol.130
, pp. 6131-6136
-
-
Subtelny, A.O.1
Hartman, M.C.2
Szostak, J.W.3
-
71
-
-
79953004613
-
Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation
-
Subtelny, A. O., Hartman, M. C., and Szostak, J. W. (2011). Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation. Angew. Chem. Int. Ed. Engl. 50, 3164-3167. doi: 10.1002/anie.201007686
-
(2011)
Angew. Chem. Int. Ed. Engl
, vol.50
, pp. 3164-3167
-
-
Subtelny, A.O.1
Hartman, M.C.2
Szostak, J.W.3
-
72
-
-
80054780096
-
In vitro methods for peptide display and their applications
-
Ullman, C. G., Frigotto, L., and Cooley, R. N. (2011). In vitro methods for peptide display and their applications. Brief. Funct. Genomics 10, 125-134. doi: 10.1093/bfgp/elr010
-
(2011)
Brief. Funct. Genomics
, vol.10
, pp. 125-134
-
-
Ullman, C.G.1
Frigotto, L.2
Cooley, R.N.3
-
73
-
-
0037030653
-
Molecular properties that influence the oral bioavailability of drug candidates
-
Veber, D. F., Johnson, S. R., Cheng, H. Y., Smith, B. R., Ward, K. W., and Kopple, K. D. (2002). Molecular properties that influence the oral bioavailability of drug candidates. J. Med. Chem. 45, 2615-2623. doi: 10.1021/jm020017n
-
(2002)
J. Med. Chem
, vol.45
, pp. 2615-2623
-
-
Veber, D.F.1
Johnson, S.R.2
Cheng, H.Y.3
Smith, B.R.4
Ward, K.W.5
Kopple, K.D.6
-
74
-
-
84929084835
-
Exploring experimental and computational markers of cyclic peptides: charting islands of permeability
-
Wang, C. K., Northfield, S. E., Swedberg, J. E., Colless, B., Chaousis, S., Price, D. A., et al. (2015). Exploring experimental and computational markers of cyclic peptides: charting islands of permeability. Eur. J. Med. Chem. 97, 202-213. doi: 10.1016/j.ejmech.2015.04.049
-
(2015)
Eur. J. Med. Chem
, vol.97
, pp. 202-213
-
-
Wang, C.K.1
Northfield, S.E.2
Swedberg, J.E.3
Colless, B.4
Chaousis, S.5
Price, D.A.6
-
75
-
-
80054853098
-
On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds
-
White, T. R., Renzelman, C. M., Rand, A. C., Rezai, T., McEwen, C. M., Gelev, V. M., et al. (2011). On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds. Nat. Chem. Biol. 7, 810-817. doi: 10.1038/nchembio.664
-
(2011)
Nat. Chem. Biol
, vol.7
, pp. 810-817
-
-
White, T.R.1
Renzelman, C.M.2
Rand, A.C.3
Rezai, T.4
McEwen, C.M.5
Gelev, V.M.6
-
76
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., et al. (1996). Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273, 458-464.
-
(1996)
Science
, vol.273
, pp. 458-464
-
-
Wrighton, N.C.1
Farrell, F.X.2
Chang, R.3
Kashyap, A.K.4
Barbone, F.P.5
Mulcahy, L.S.6
-
77
-
-
47549110353
-
Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme
-
Xiao, H., Murakami, H., Suga, H., and Ferré-D'Amaré, A. R. (2008). Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme. Nature 454, 358-361. doi: 10.1038/nature07033
-
(2008)
Nature
, vol.454
, pp. 358-361
-
-
Xiao, H.1
Murakami, H.2
Suga, H.3
Ferré-D'Amaré, A.R.4
|