-
4
-
-
84926952692
-
-
ed. R. Luisi and V. Capriati, Wiley-VCH, Weinheim, 1st edn, ch. 7
-
L. Degennaro, B.Musio and R.Luisi, in Lithium Compounds in Organic Synthesis-From Fundamentals to Applications, ed. R. Luisi and V. Capriati, Wiley-VCH, Weinheim, 1st edn, 2014, ch. 7, pp. 191-223
-
(2014)
Lithium Compounds in Organic Synthesis-From Fundamentals to Applications
, pp. 191-223
-
-
Degennaro, L.1
Musio, B.2
Luisi, R.3
-
15
-
-
84889100044
-
-
A. D. Morley A. Pugliese K. Birchall J. Bower P. Brennan N. Brown T. Chapman M. Drysdale I. H. Gilbert S. Hoelder A. Jordan S. V. Ley A. Merritt D. Miller M. E. Swarbrick P. G. Wyatt Drug Discovery Today 2013 18 1221-1227
-
(2013)
Drug Discovery Today
, vol.18
, pp. 1221-1227
-
-
Morley, A.D.1
Pugliese, A.2
Birchall, K.3
Bower, J.4
Brennan, P.5
Brown, N.6
Chapman, T.7
Drysdale, M.8
Gilbert, I.H.9
Hoelder, S.10
Jordan, A.11
Ley, S.V.12
Merritt, A.13
Miller, D.14
Swarbrick, M.E.15
Wyatt, P.G.16
-
28
-
-
27844533939
-
-
H. Bräuner-Osborne L. Bunch N. Chopin F. Couty G. Evano A. A. Jensen M. Kusk B. Nielsen N. Rabasso Org. Biomol. Chem. 2005 3 3926
-
(2005)
Org. Biomol. Chem.
, vol.3
, pp. 3926
-
-
Bräuner-Osborne, H.1
Bunch, L.2
Chopin, N.3
Couty, F.4
Evano, G.5
Jensen, A.A.6
Kusk, M.7
Nielsen, B.8
Rabasso, N.9
-
30
-
-
67650003004
-
-
T. Hart A. T. Macias K. Benwell T. Brooks J. D'Alessandro P. Dokurno G. Francis B. Gibbons T. Haymes G. Kennett S. Lightowler H. Mansell N. Matassova A. Misra A. Padfield R. Parsons R. Pratt A. Robertson S. Walls M. Wong S. Roughley Bioorg. Med. Chem. Lett. 2009 19 4241-4244
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 4241-4244
-
-
Hart, T.1
Macias, A.T.2
Benwell, K.3
Brooks, T.4
D'Alessandro, J.5
Dokurno, P.6
Francis, G.7
Gibbons, B.8
Haymes, T.9
Kennett, G.10
Lightowler, S.11
Mansell, H.12
Matassova, N.13
Misra, A.14
Padfield, A.15
Parsons, R.16
Pratt, R.17
Robertson, A.18
Walls, S.19
Wong, M.20
Roughley, S.21
more..
-
31
-
-
85006916141
-
-
K. Gerlach, H.Priepke, W.Weinen, A.Schuler-Metz and H.Nar, WIPO Pat, WO2008/135525A2, 2008
-
(2008)
WIPO Pat
-
-
Gerlach, K.1
Priepke, H.2
Weinen, W.3
Schuler-Metz, A.4
Nar, H.5
-
32
-
-
85006850626
-
-
Chem. Abstr. 2008 149 556457
-
(2008)
Chem. Abstr.
, vol.149
, pp. 556457
-
-
-
33
-
-
80054090549
-
-
ed. C. V. Stevens, Elsevier, Oxford, 3rd edn, vol.
-
G. S. Singh, M.D'hooghe and N.De Kimpe, in Comprehensive Heterocyclic Chemistry III, ed. C. V. Stevens, Elsevier, Oxford, 3rd edn, 2008, vol. 2, pp. 1-110
-
(2008)
Comprehensive Heterocyclic Chemistry III
, vol.2
, pp. 1-110
-
-
Singh, G.S.1
D'hooghe, M.2
De Kimpe, N.3
-
34
-
-
72049126821
-
-
ed. E. Schaumann and D. Enders, Thieme, Stuttgart, vol.
-
F. Couty, in Science of Synthesis, ed. E. Schaumann and D. Enders, Thieme, Stuttgart, 2009, vol. 40a, pp. 773-816
-
(2009)
Science of Synthesis
, vol.40a
, pp. 773-816
-
-
Couty, F.1
-
35
-
-
84865443841
-
-
in, ed. J. Alzerez-Builla, J. J. Vaquero and J. Barluenga, Wiley-VCH, Weinheim, 1st edn, vol.
-
G. Rousseau and S.Robin, in Modern Heterocyclic Chemistry, ed. J. Alzerez-Builla, J. J. Vaquero and J. Barluenga, Wiley-VCH, Weinheim, 1st edn, 2011, vol. 1, pp. 163-268
-
(2011)
Modern Heterocyclic Chemistry
, vol.1
, pp. 163-268
-
-
Rousseau, G.1
Robin, S.2
-
39
-
-
85006938625
-
-
D. R. Adams, J.Bentley, C. D.Bodkin, I. A.Cliffe, J. E. P.Davidson, H. L.Mansell, N. J.Monck, R. G.Shepherd and J. M.Shepherd, US Pat, 6831078, 2004
-
(2004)
US Pat
, pp. 6831078
-
-
Adams, D.R.1
Bentley, J.2
Bodkin, C.D.3
Cliffe, I.A.4
Davidson, J.E.P.5
Mansell, H.L.6
Monck, N.J.7
Shepherd, R.G.8
Shepherd, J.M.9
-
40
-
-
85006887202
-
-
WO
-
S. R. Brunette, A.Abeywardane, M. J.Burke, S. R.Kapadia, T. M.Kirrane Jr., M. R.Netherton, H.Razavi, S.Rodriguez, A.Saha, R.Sibley, K.Smith Keenan, L.Lana, H.Takahashi, M. R.Turner, J.-P.Wu, E. R. R.Young, Q.Zhang, Q.Zhang and R. M.Zindell, WOWO2013/134226A1, 2013
-
(2013)
-
-
Brunette, S.R.1
Abeywardane, A.2
Burke, M.J.3
Kapadia, S.R.4
Kirrane, T.M.5
Netherton, M.R.6
Razavi, H.7
Rodriguez, S.8
Saha, A.9
Sibley, R.10
Smith Keenan, K.11
Lana, L.12
Takahashi, H.13
Turner, M.R.14
Wu, J.-P.15
Young, E.R.R.16
Zhang, Q.17
Zhang, Q.18
Zindell, R.M.19
-
41
-
-
84862232471
-
-
D. W. Kung S. B. Coffey R. M. Jones S. Cabral W. Jiao M. Fichtner P. A. Carpino C. R. Rose R. F. Hank M. G. Lopaze R. Swartz H. T. Chen Z. Hendsch B. Posner C. F. Wielis B. Manning J. Dubins I. A. Stock S. Varma M. Campbell D. DeBartola R. Kosa-Maines S. J. Steyn K. F. McClure Bioorg. Med. Chem. Lett. 2012 22 4281
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 4281
-
-
Kung, D.W.1
Coffey, S.B.2
Jones, R.M.3
Cabral, S.4
Jiao, W.5
Fichtner, M.6
Carpino, P.A.7
Rose, C.R.8
Hank, R.F.9
Lopaze, M.G.10
Swartz, R.11
Chen, H.T.12
Hendsch, Z.13
Posner, B.14
Wielis, C.F.15
Manning, B.16
Dubins, J.17
Stock, I.A.18
Varma, S.19
Campbell, M.20
DeBartola, D.21
Kosa-Maines, R.22
Steyn, S.J.23
McClure, K.F.24
more..
-
42
-
-
84893685653
-
-
J. M. Keith W. M. Jones J. M. Pierce M. Seierstad J. A. Palmer M. Webb M. J. Karbarz B. P. Scott S. J. Wilson L. Luo M. L. Wennerholm L. Chang S. M. Brown M. Rizzolio R. Rynberg S. R. Chaplan J. G. Breitenbucher Bioorg. Med. Chem. Lett. 2014 24 737
-
(2014)
Bioorg. Med. Chem. Lett.
, vol.24
, pp. 737
-
-
Keith, J.M.1
Jones, W.M.2
Pierce, J.M.3
Seierstad, M.4
Palmer, J.A.5
Webb, M.6
Karbarz, M.J.7
Scott, B.P.8
Wilson, S.J.9
Luo, L.10
Wennerholm, M.L.11
Chang, L.12
Brown, S.M.13
Rizzolio, M.14
Rynberg, R.15
Chaplan, S.R.16
Breitenbucher, J.G.17
-
44
-
-
84892862408
-
-
L. Degennaro M. Zenzola P. Trinchera L. Carroccia A. Giovine G. Romanazzi A. Falcicchio R. Luisi Chem. Commun. 2014 50 1698-1700
-
(2014)
Chem. Commun.
, vol.50
, pp. 1698-1700
-
-
Degennaro, L.1
Zenzola, M.2
Trinchera, P.3
Carroccia, L.4
Giovine, A.5
Romanazzi, G.6
Falcicchio, A.7
Luisi, R.8
-
56
-
-
3843119491
-
-
Angew. Chem. Int. Ed. Engl. 15 313 314
-
D. Seebach W. Lubosch Angew. Chem. 1976 88 339-340 Angew. Chem., Int. Ed. Engl. 1976 15 313-314
-
(1976)
Angew. Chem.
, vol.88
, pp. 339-340
-
-
Seebach, D.1
Lubosch, W.2
-
59
-
-
33846939147
-
-
ed. V. Snieckus and M. Majewski, Thieme, Stuttgart, vol.
-
R. E. Gawley, S.O'Connor and R.Klein, in Science of Synthesis, ed. V. Snieckus and M. Majewski, Thieme, Stuttgart, 2006, vol. 8a, pp. 677-757
-
(2006)
Science of Synthesis
, vol.8a
, pp. 677-757
-
-
Gawley, R.E.1
O'Connor, S.2
Klein, R.3
-
75
-
-
85006956434
-
-
The NMR-determined rotational barriers for N-thiopivaloyl-2-methylazetidine and N-Boct-2-methylazetidine at 25 °C (70.7 and 75.0 kJ molrespectively) indicate rotation half-lives (for the major conformer) of 0.3 and 1.6 s. However, these extend to 2.1 and 116 days at −78 °C, strongly suggesting that rotamer interconversion is not significant under lithiation condition
-
The NMR-determined rotational barriers for N-thiopivaloyl-2-methylazetidine and N-Boct-2-methylazetidine at 25 °C (70.7 and 75.0 kJ mol−1, respectively) indicate rotation half-lives (for the major conformer) of 0.3 and 1.6 s. However, these extend to 2.1 and 116 days at −78 °C, strongly suggesting that rotamer interconversion is not significant under lithiation condition
-
-
-
-
83
-
-
84921360597
-
-
M. Zenzola L. Degennaro P. Trinchera L. Carroccia A. Giovine G. Romanazzi P. Mastrorilli R. Rizzi L. Pisano R. Luisi Chem.-Eur. J. 2014 20 12190-12200
-
(2014)
Chem.-Eur. J.
, vol.20
, pp. 12190-12200
-
-
Zenzola, M.1
Degennaro, L.2
Trinchera, P.3
Carroccia, L.4
Giovine, A.5
Romanazzi, G.6
Mastrorilli, P.7
Rizzi, R.8
Pisano, L.9
Luisi, R.10
-
88
-
-
84891576205
-
-
Wiley-VCH, Weinheim, 2nd edn, vol.
-
D. G. Hall, Boronic Acids: Preparation and Applications in Organic Synthesis, Medicine and Materials, Wiley-VCH, Weinheim, 2nd edn, 2011, vol. 1 and 2
-
(2011)
Boronic Acids: Preparation and Applications in Organic Synthesis, Medicine and Materials
, vol.1 and 2
-
-
Hall, D.G.1
-
90
-
-
0004205240
-
-
RSC, Cambridge, UK
-
M. Davison, A. K.Hughes, T. B.Marder and K.Wade, Contemporary Boron Chemistry, RSC, Cambridge, UK, 2000
-
(2000)
Contemporary Boron Chemistry
-
-
Davison, M.1
Hughes, A.K.2
Marder, T.B.3
Wade, K.4
-
96
-
-
49649125633
-
-
M. A. J. Duncton M. A. Estiarte D. Tan C. Kaub D. J. R. O'Mahony R. J. Johnson M. Cox W. T. Edwards M. Wan J. Kincaid M. G. Kelly Org. Lett. 2008 10 3259
-
(2008)
Org. Lett.
, vol.10
, pp. 3259
-
-
Duncton, M.A.J.1
Estiarte, M.A.2
Tan, D.3
Kaub, C.4
O'Mahony, D.J.R.5
Johnson, R.J.6
Cox, M.7
Edwards, W.T.8
Wan, M.9
Kincaid, J.10
Kelly, M.G.11
-
98
-
-
84916237639
-
-
B. Barré L. Gonnard R. Campagne S. Reymond J. Marin P. Ciapetti M. Brellier A. Guérinot J. Cossy Org. Lett. 2014 16 6160
-
(2014)
Org. Lett.
, vol.16
, pp. 6160
-
-
Barré, B.1
Gonnard, L.2
Campagne, R.3
Reymond, S.4
Marin, J.5
Ciapetti, P.6
Brellier, M.7
Guérinot, A.8
Cossy, J.9
-
100
-
-
84990940827
-
-
G. Parisi M. Zenzola E. Capitanelli C. Carlucci G. Romanazzi L. Pisano L. Degennaro R. Luisi Pure Appl. Chem. 2016 88 631-648
-
(2016)
Pure Appl. Chem.
, vol.88
, pp. 631-648
-
-
Parisi, G.1
Zenzola, M.2
Capitanelli, E.3
Carlucci, C.4
Romanazzi, G.5
Pisano, L.6
Degennaro, L.7
Luisi, R.8
|