Fragment-based hit identification: Thinking in 3D

Drug Discovery Today

Volumn 18, Issue 23-24, 2013, Pages 1221-1227

  Morley, Andrew D ^a   Pugliese, Angelo ^b   Birchall, Kristian ^c   Bower, Justin ^b   Brennan, Paul ^d   Brown, Nathan ^e   Chapman, Tim ^c   Drysdale, Martin ^b   Gilbert, Ian H ^a   Hoelder, Swen ^e   Jordan, Allan ^f   Ley, Steven V ^g   Merritt, Andy ^c   Miller, David ^h   Swarbrick, Martin E ⁱ   Wyatt, Paul G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁱ Cancer Research UK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG; MOLECULAR LIBRARY;

DRUG DATABASE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SYNTHESIS; REVIEW; THREE DIMENSIONAL IMAGING; CHEMISTRY; CONFORMATION; COOPERATION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG INDUSTRY; HUMAN; MOLECULAR LIBRARY; ORGANIZATION AND MANAGEMENT; PROCEDURES; TRENDS;

COOPERATIVE BEHAVIOR; DRUG DESIGN; DRUG DISCOVERY; DRUG INDUSTRY; HUMANS; MOLECULAR CONFORMATION; SMALL MOLECULE LIBRARIES;

EID: 84889100044     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2013.07.011     Document Type: Review

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