Heterologous expression of toxins from bacterial toxin-antitoxin systems in eukaryotic cells: Strategies and applications

Toxins

Volumn 8, Issue 2, 2016, Pages

  Yeo, Chew Chieng ^a   Bakar, Fauziah Abu ^b   Chan, Wai Ting ^c   Espinosa, Manuel ^c   Harikrishna, Jennifer Ann ^b  

^a UNIVERSITI SULTAN ZAINAL ABIDIN   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Anticancer therapy; Antiviral therapy; Cell ablation; Gene containment; Gene therapy; Genetic manipulation; High expression cell lines; Toxin antitoxin systems

Indexed keywords

BACTERIAL TOXIN; BARNASE; BARSTAR; DOXYCYCLINE; MESSENGER RNA; PLASMID DNA; RETROVIRUS VECTOR; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; ANTITOXIN;

ANTIVIRAL THERAPY; AUXOTROPHY; BACTERIAL GENOME; CANCER GENE THERAPY; CAULIFLOWER MOSAIC VIRUS; CELL GROWTH; CYTOMEGALOVIRUS; EUKARYOTIC CELL; GENETIC MANIPULATION; HEPATITIS C VIRUS; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; INTERNAL RIBOSOME ENTRY SITE; KOMAGATAELLA PASTORIS; LONG TERMINAL REPEAT; NONHUMAN; RECOMBINANT PLASMID; REVIEW; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; TOXIN ANTITOXIN SYSTEM; TRANSGENIC ORGANISM; TRANSGENIC PLANT; TYPE IV SECRETION SYSTEM; ANIMAL; GENE THERAPY; GENETIC ENGINEERING; GENETICS; METABOLISM; YEAST;

ANIMALS; ANTITOXINS; BACTERIAL TOXINS; EUKARYOTIC CELLS; GENETIC ENGINEERING; GENETIC THERAPY; HUMANS; YEASTS;

EID: 85006822970     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/TOXINS8020049     Document Type: Review

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