Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Science Advances

Volumn 2, Issue 7, 2016, Pages

  Karunakaran, Denuja ^a   Geoffrion, Michele ^a   Wei, Lihui ^a   Gan, Wei ^a   Richards, Laura ^a   Shangari, Prakriti ^a   DeKemp, Ella M ^a   Beanlands, Rachelle A ^a   Perisic, Ljubica ^b   Maegdefessel, Lars ^b   Hedin, Ulf ^b   Sad, Subash ^c   Guo, Liang ^d   Kolodgie, Frank D ^d   Virmani, Renu ^d   Ruddy, Terrence ^a   Rayner, Katey J ^a,c  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF OTTAWA   (Canada)

^d CVPATH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELLS; CYTOLOGY; MACROPHAGES; MAMMALS; PHOSPHORYLATION;

ATHEROSCLEROTIC PLAQUE; LOW DENSITY LIPOPROTEINS; MOLECULAR INSIGHTS; MOLECULAR MECHANISM; MYOCARDIAL INFARCTION; PLAQUE PROGRESSION; THERAPEUTIC TOOLS; VULNERABLE PLAQUES;

DISEASES;

APOLIPOPROTEIN E; BENZYLOXYCARBONYL-VALYL-ASPARTIC ACID FLUOROMETHYL KETONE; CHOLESTEROL; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN; MLKL PROTEIN, HUMAN; NECROSTATIN-1; OXIDIZED LOW DENSITY LIPOPROTEIN; PEPTIDE CHLOROMETHYL KETONE; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, HUMAN;

ANIMAL; APOPTOSIS; ATHEROSCLEROSIS; BLOOD; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CORONARY BLOOD VESSEL; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; HUMAN; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MOUSE; NECROSIS; PATHOLOGY; VETERINARY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; BONE MARROW CELLS; CELLS, CULTURED; CHOLESTEROL; CORONARY VESSELS; HUMANS; IMIDAZOLES; INDOLES; INTERLEUKIN-1BETA; LIPOPROTEINS, LDL; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES;

EID: 85006622606     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1600224     Document Type: Article

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