Cell death in human atherosclerotic plaques involves both oncosis and apoptosis

Atherosclerosis

Volumn 130, Issue 1-2, 1997, Pages 17-27

  Crisby, Milita ^a   Kallin, Bengt ^a   Thyberg, Johan ^b   Zhivotovsky, Boris ^b   Orrenius, Sten ^b   Kostulas, Vasilios ^a   Nilsson, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

apoptosis; atherosclerosis; oncosis

Indexed keywords

ADULT; AGED; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL DEATH; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

EID: 0030967474     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)06037-6     Document Type: Article

References (30)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801.
2. Lendon CL, Davies MJ, Born GVR, Richardson PD. Atherosclerotic plaque caps are locally weakened when macrophage density is increased. Atherosclerosis 1991;87:87.
3. Van der Wal AC, Becker AE, Van der Loos CM, Das PK. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994;89:36.
4. Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994;94:2493.
5. Guyton JR, Black BL, Seidel CL. Focal toxicity in vascular smooth muscle cell culture. A model of atherosclerotic core region. Am J Pathol 1990;137:425.
6. Esterbauer H, Wag G, H P. Lipid peroxidation and its role in atherosclerosis. Br Med Bull 1993;49:566.
7. Leszczynski D, Zhao Y, Luokkamäki M, Foegh ML. Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells. Am J Pathol 1994;145:1265.
8. Cho A, Courtman D, Langille Lowell B. Apoptosis (Programmed Cell Death) in arteries of the neonatal lamb. Circ Res 1995;76:168.
9. Isner MJ, Kearney M, Bortman S, Passeri J. Apoptosis in human atherosclerosis and restenosis. Circulation 1995;91:2703.
10. Bennett R, Martin G, Evan I, Schwartz MS. Apoptosis in human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J Clin Invest 1995;95:2266.
11. Han DK, Haudenschild CC, Hong MK, Tinkle BT, Leon MIB, Liau G. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol 1995;147:267.
12. Geng Y-J, Libby P. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1b-converting enzyme. Am J Pathol 1995;147:251.
13. Bochatan-Piallat M-L, Gabbiani F, Redard M, Desmoulire A, Gabbiani G. Apoptosis participates in cellular regulation during rat aortic intimal thickening. Am J Pathol 1995;146:1059.
14. Steller H. Mechanisms and genes of cellular suicide. Science 1995;267:1445.
15. Nagata S, Goldstein P. The Fas death factor. Science 1995;267:1449.
16. Thompson BC. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456.
17. Kerr JFR, Winterford CM, Harmon BV. Morphological criteria for identifying apoptosis. In: Celis JE. (ed). Cell Biology. A Laboratory Handbook. Academic, 1994;319-329.
18. Collaborators NASCET. Beneficial effect of carotid endarterectomy in symptomatic patients with high grade carotid stenosis. New Engl J Med 1991;325:445.
19. Gold R, Schmied M, Rothe G, Zischler H, Breitshopf H, Wekerle H, Lassman H. Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture system and tissue sections. J Histochem Cytochem 1993;41:1023.
20. Tsukada T, Tippens D, Gordon D, Ross R, Gown A. HHF35, a muscle-actin-specific monoclonal antibody: I. Immunocytochemical and biochemical characterization. Am J Pathol 1987;126:51-60.
21. Gold R, Schied M, Giegerich G, Breitschpf H, Hartung BP, Toyka KV, Lassman H. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 1994;71:219.
22. Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Burkowska K, Bursch W, Schulte-Hermann R. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 1995;21:1465.
23. Bennett MR, Evan GI, Schwartz SM. Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways. Circ Res 1995;77:266.
24. Bennett MR, Gibson DF, Schwartz SM, Tait JF. Binding and phagocytosis of apoptotic smooth muscle cells is mediated in part by exposure of phosphatidylserine. Circ Res 1995;77:1136.
25. Campbell GR, Campbell JH. Smooth muscle phenotypic changes in arterial wall homeostasis: implications for the pathogenesis of atherosclerosis. Exp Mol Pathol 1985;42:139.
26. Davies MJ, Thomas AC. Plaque fissuring: The cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. Br Heart J 1985;53:363.
27. Fuster V, Badimon L, Cohen M, Ambrose J, Badimon J, Chesebro J. Insights into the pathogenesis of acute ischemic syndromes. Circulation 1988;77:1213.
28. Falk E. Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes. Am. J Cardiol 1989;63:114E.
29. Richardson PD, Davies MJ, Born GVR. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet 1989;2:941.
30. Bocan T, Schifani T, Guyton J. Ultrastructure of the human aortic fibrolipid lesion: Formation of the atherosclerotic lipid-rich core. Am J Pathol 1986;123:413.