A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging

Human Molecular Genetics

Volumn 25, Issue 19, 2016, Pages 4186-4200

  Baroncelli, Laura ^a   Molinaro, Angelo ^a,b   Cacciante, Francesco ^c   Alessandrı, Maria Grazia ^d   Napoli, Debora ^c   Putignano, Elena ^a   Tola, Jonida ^a   Leuzzi, Vincenzo ^e   Cioni, Giovanni ^d,f   Pizzorusso, Tommaso ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c SCUOLA NORMALE SUPERIORE   (Italy)

^d DEPARTMENT OF DEVELOPMENTAL NEUROSCIENCE   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CRE RECOMBINASE; CREATINE TRANSPORTER; LIPOFUSCIN; NESTIN; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; CREATINE; PLASMA MEMBRANE NEUROTRANSMITTER TRANSPORTER;

ADULT; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; AUTOFLUORESCENCE; BRAIN DISEASE; CELL ACTIVATION; CELL AGING; CEREBRAL CREATINE DEFICIENCY SYNDROME 1; CINGULATE GYRUS; COGNITIVE DEFECT; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); DECLARATIVE MEMORY; FEMALE; HIPPOCAMPUS; INTELLECTUAL IMPAIRMENT; LONGITUDINAL STUDY; MALE; MEMORY DISORDER; MICROGLIA; MOUSE; MOUSE MODEL; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHOLOGY; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFECT; STEREOMETRY; SYNAPSE; WORKING MEMORY; ANIMAL; BRAIN; DEFICIENCY; DISEASE MODEL; GENETICS; HUMAN; METABOLIC ENCEPHALOPATHY; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE; X LINKED MENTAL RETARDATION;

AGING; ANIMALS; BRAIN; BRAIN DISEASES, METABOLIC, INBORN; COGNITIVE DYSFUNCTION; CREATINE; DISEASE MODELS, ANIMAL; HUMANS; INTELLECTUAL DISABILITY; MEMBRANE TRANSPORT PROTEINS; MENTAL RETARDATION, X-LINKED; MICE; MICE, TRANSGENIC; PLASMA MEMBRANE NEUROTRANSMITTER TRANSPORT PROTEINS;

EID: 85006441195     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw252     Document Type: Article

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