Immunohistochemical localisation of the creatine transporter in the rat brain

Neuroscience

Volumn 163, Issue 2, 2009, Pages 571-585

  Mak, C S W ^a   Waldvogel, H J ^a   Dodd, J R ^b   Gilbert, R T ^a   Lowe, M T J ^a   Birch, N P ^b   Faull, R L M ^a   Christie, D L ^b  

^a THE UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

cerebellum; hippocampus; olfactory bulb

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARRIER PROTEINS AND BINDING PROTEINS; CREATINE TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN; BRAIN STEM; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRANIAL NERVE; DENTATE GYRUS; ENERGY METABOLISM; FOREBRAIN; IMMUNOHISTOCHEMISTRY; LEARNING; LIMBIC SYSTEM; MALE; MEMORY; NERVE DEGENERATION; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PURKINJE CELL; PYRAMIDAL NERVE CELL; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL CORD VENTRAL HORN; TISSUE DISTRIBUTION; WHITE MATTER;

ANIMALS; BRAIN; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, CONFOCAL; NEURONS; PHOTOMICROGRAPHY; RATS; RATS, WISTAR;

EID: 69249216470     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.06.065     Document Type: Article

References (41)

1. Acosta M.L., Kalloniatis M., and Christie D.L. Creatine transporter localization in developing and adult retina: importance of creatine to retinal function. Am J Physiol Cell Physiol 289 (2005) C1015-C1023
2. Almeida L.S., Salomons G.S., Hogenboom F., Jakobs C., and Schoffelmeer A.N. Exocytotic release of creatine in rat brain. Synapse 60 (2006) 118-123
3. Ames III A. CNS energy metabolism as related to function. Brain Res Brain Res Rev 34 (2000) 42-68
4. Andres R.H., Ducray A.D., Schlattner U., Wallimann T., and Widmer H.R. Functions and effects of creatine in the central nervous system. Brain Res Bull 76 (2008) 329-343
5. Boero J., Qin W., Cheng J., Woolsey T.A., Strauss A.W., and Khuchua Z. Restricted neuronal expression of ubiquitous mitochondrial creatine kinase: changing patterns in development and with increased activity. Mol Cell Biochem 244 (2003) 69-76
6. Braissant O., Bachmann C., and Henry H. Expression and function of AGAT, GAMT and CT1 in the mammalian brain. Subcell Biochem 46 (2007) 67-81
7. Braissant O., and Henry H. AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review. J Inherit Metab Dis 31 (2008) 230-239
8. Braissant O., Henry H., Loup M., Eilers B., and Bachmann C. Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study. Brain Res Mol Brain Res 86 (2001) 193-201
9. Brosnan J.T., and Brosnan M.E. Creatine: endogenous metabolite, dietary, and therapeutic supplement. Annu Rev Nutr 27 (2007) 241-261
10. Christie D.L. Functional insights into the creatine transporter. In: Salomons G.S., and Wyss M. (Eds). Creatine and creatine kinase in health and disease Vol. 46 (2007), Springer, Dordrecht, The Netherlands 99-118
11. Couzin J. Clinical research. Testing a novel strategy against Parkinson's disease. Science 315 (2007) 1778
12. Dodd J.R., and Christie D.L. Cysteine 144 in the third transmembrane domain of the creatine transporter is located close to a substrate-binding site. J Biol Chem 276 (2001) 46983-46988
13. Gonzalez A.M., and Uhl G.R. 'Choline/orphan V8-2-1/creatine transporter' mRNA is expressed in nervous, renal and gastrointestinal systems. Brain Res Mol Brain Res 23 (1994) 266-270
14. Guimbal C., and Kilimann M.W. A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidneycDNA cloning and functional expression. J Biol Chem 268 (1993) 8418-8421
15. Happe H.K., and Murrin L.C. In situ hybridization analysis of CHOT1, a creatine transporter, in the rat central nervous system. J Comp Neurol 351 (1995) 94-103
16. Hedreen J.C., and DeLong M.R. Organization of striatopallidal, striatonigral, and nigrostriatal projections in the macaque. J Comp Neurol 304 (1991) 569-595
17. Leverenz J.B., Agustin C.M., Tsuang D., Peskind E.R., Edland S.D., Nochlin D., DiGiacomo L., Bowen J.D., McCormick W.C., Teri L., Raskind M.A., Kukull W.A., and Larson E.B. Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study. Arch Neurol 59 (2002) 1099-1106
18. MacDonald V., and Halliday G.M. Selective loss of pyramidal neurons in the pre-supplementary motor cortex in Parkinson's disease. Mov Disord 17 (2002) 1166-1173
19. McGeorge A.J., and Faull R.L.M. The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience 29 (1989) 503-537
20. Ohtsuki S., Tachikawa M., Takanaga H., Shimizu H., Watanabe M., Hosoya K., and Terasaki T. The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain. J Cereb Blood Flow Metab 22 (2002) 1327-1335
21. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. 6th ed. (2007), Academic Press, London
22. --creatine transporter: functional, molecular characterization and localization. J Physiol 545 (2002) 133-144
23. Perasso L., Cupello A., Lunardi G.L., Principato C., Gandolfo C., and Balestrino M. Kinetics of creatine in blood and brain after intraperitoneal injection in the rat. Brain Res 974 (2003) 37-42
24. Price J.L., Ko A.I., Wade M.J., Tsou S.K., McKeel D.W., and Morris J.C. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch Neurol 58 (2001) 1395-1402
25. Rosenberg E.H., Almeida L.S., Kleefstra T., deGrauw R.S., Yntema H.G., Bahi N., Moraine C., Ropers H.H., Fryns J.P., deGrauw T.J., Jakobs C., and Salomons G.S. High prevalence of SLC6A8 deficiency in X-linked mental retardation. Am J Hum Genet 75 (2004) 97-105
26. Saltarelli M.D., Bauman A.L., Moore K.R., Bradley C.C., and Blakely R.D. Expression of the rat brain creatine transporter in situ and in transfected HeLa cells. Dev Neurosci 18 (1996) 524-534
27. Schlattner U., Tokarska-Schlattner M., and Wallimann T. Mitochondrial creatine kinase in human health and disease. Biochim Biophys Acta 1762 (2006) 164-180
28. Schloss P., Mayser W., and Betz H. The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues. Biochem Biophys Res Commun 198 (1994) 637-645
29. Schmidt-Kastner R., and Freund T.F. Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40 (1991) 599-636
30. Shipley M.T., McLean J.H., and Ennis M. Olfactory system. In: Paxinos G. (Ed). The rat nervous system. 2nd ed. (1995), Academic Press, San Diego 899-921
31. Speer O., Neukomm L.J., Murphy R.M., Zanolla E., Schlattner U., Henry H., Snow R.J., and Wallimann T. Creatine transporters: a reappraisal. Mol Cell Biochem 256-257 (2004) 407-424
32. Stockler S., Schulz P.W., and Salomons G.S. Cerebral creatine deficiency syndromes: clinical aspects treatment and pathophysiology. In: Salomons G.S., and Wyss M. (Eds). Creatine and creatine kinase in health and disease Vol. 46 (2007), Springer, Dordrecht, The Netherlands 149-166
33. Stromberger C., Bodamer O.A., and Stockler-Ipsiroglu S. Clinical characteristics and diagnostic clues in inborn errors of creatine metabolism. J Inherit Metab Dis 26 (2003) 299-308
34. Tachikawa M., Fukaya M., Terasaki T., Ohtsuki S., and Watanabe M. Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-MI and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis. Eur J Neurosci 20 (2004) 144-160
35. Tolbert D.L., Bantli H., and Bloedel J.R. Multiple branching of cerebellar efferent projections in cats. Exp Brain Res 31 (1978) 305-316
36. Van Hoesen G.W., Yeterian E.H., and Lavizzo-Mourey R. Widespread corticostriate projections from temporal cortex of the rhesus monkey. J Comp Neurol 199 (1981) 205-219
37. Voogd J. Cerebellum. In: Paxinos G. (Ed). The rat nervous system. 2nd ed. (1995), Academic Press, San Diego 309-344
38. West M., Park D., Dodd J.R., Kistler J., and Christie D.L. Purification and characterization of the creatine transporter expressed at high levels in HEK293 cells. Protein Expr Purif 41 (2005) 393-401
39. Wu Y., Wang W., Diez-Sampedro A., and Richerson G.B. Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron 56 (2007) 851-865
40. Wyss M., and Kaddurah-Daouk R. Creatine and creatinine metabolism. Physiol Rev 80 (2000) 1107-1213
41. Wyss M., and Schulze A. Health implications of creatine: can oral creatine supplementation protect against neurological and atherosclerotic disease?. Neuroscience 112 (2002) 243-260