Kinetic stability and cellular uptake of lutein in WPI-stabilised nanoemulsions and emulsions prepared by emulsification and solvent evaporation method

Food Chemistry

Volumn 221, Issue , 2017, Pages 1269-1276

  Teo, Anges ^a,b   Lee, Sung Je ^a   Goh, Kelvin K T ^b   Wolber, Frances M ^b  

^a MASSEY UNIVERSITY   (New Zealand)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

Cellular uptake; Cytotoxicity; Emulsions; Encapsulation; Kinetic stability; Lutein; Nanoemulsions

Indexed keywords

CELL CULTURE; CYTOTOXICITY; EMULSIONS; ENCAPSULATION; EVAPORATION; PARTICLE SIZE; PROTEINS;

CELLULAR UPTAKE; CONVENTIONAL EMULSIONS; DELIVERY SYSTEMS; ENCAPSULATION EFFICIENCY; KINETIC STABILITY; LUTEIN; NANO-EMULSIONS; SOLVENT EVAPORATION METHOD;

EMULSIFICATION;

ACETIC ACID; ACETIC ACID ETHYL ESTER; ACETONITRILE; METHANOL; SOLVENT; WHEY PROTEIN; XANTHOPHYLL; EMULSION; NANOPARTICLE;

ARTICLE; CACO-2 CELL LINE; CELL TRANSPORT; CELL VIABILITY; COLOR; CONTROLLED STUDY; EMULSION; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTESTINE CELL; MOLECULAR STABILITY; NANOEMULSION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROTEIN CONTENT; RETENTION TIME; STORAGE TEMPERATURE; ZETA POTENTIAL; CHEMISTRY; DRUG FORMULATION; DRUG STABILITY; EVALUATION STUDY; HUMAN; KINETICS; METABOLISM; PROCEDURES;

CACO-2 CELLS; DRUG COMPOUNDING; DRUG STABILITY; EMULSIONS; HUMANS; KINETICS; LUTEIN; NANOPARTICLES; PARTICLE SIZE; SOLVENTS; WHEY PROTEINS;

EID: 85006371177     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2016.11.030     Document Type: Article

References (37)

1. Boon, C.S., McClements, D.J., Weiss, J., Decker, E.A., Factors influencing the chemical stability of carotenoids in foods. Critical Reviews in Food Science and Nutrition 50:6 (2010), 515–532.
2. Craft, N.E., Soares, J.H., Relative solubility, stability and absorptivity of lutein and β-carotene in organic solvents. Journal of Agricultural and Food Chemistry 40:3 (1992), 431–434.
3. Delgado-Vargas, F., Jimenez, A.R., Paredes-Lopez, O., Natural pigments: Carotenoids, anthocyanins, and betalains: Characteristics, biosynthesis, processing, and stability. Critical Reviews in Food Science and Nutrition 40 (2000), 173–289.
4. Eason, R.R., Velarde, M.C., Chatman, L., Till, S.R., Geng, Y., Ferguson, M.,. Simmen, R.C.M., Dietary exposure to whey proteins alters rat mammary gland proliferation, apoptosis, and gene expression during postnatal development. The Journal of Nutrition 134:12 (2004), 3370–3377.
5. Fotakis, G., Timbrell, J.A., In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicology Letters 160:2 (2006), 171–177.
6. Gallier, S., Tate, H., Singh, H., In vitro gastric and intestinal digestion of a walnut oil body dispersion. Journal of Agricultural and Food Chemistry 61:2 (2013), 410–417.
7. He, W., Tan, Y., Tian, Z., Chen, L., Hu, F., Wu, W., Food protein-stabilized nanoemulsions as potential delivery systems for poorly water-soluble drugs: Preparation, in vitro characterization, and pharmacokinetics in rats. International Journal of Nanomedicine 6 (2011), 521–533.
8. Herber, D., Plant foods and phytochemicals in human health. Berdanier, C.D., Dwyer, J., Feldman, E.B., (eds.) Handbook of nutrition and food, 2nd ed., 2008, CRC Press, Boca Raton, FL.
9. Alves-Rodrigues, A., Shao, A., The science behind lutein. Toxicology Letters 150:1 (2004), 57–83.
10. Jo, Y.J., Kwon, Y.J., Characterization of β-carotene nanoemulsions prepared by microfluidisation technique. Food Science Biotechnology 23:1 (2014), 107–114.
11. Krinsky, N.I., Landrum, J.T., Bone, R.A., Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annual Review of Nutrition 23 (2003), 171–201.
12. Kuang, P., Zhang, H., Bajaj, P.R., Yuan, Q., Tang, J., Chen, S., Sablani, S., Physicochemical properties and storage stability of lutein microcapsules prepared with maltodextrins and sucrose by spray drying. Journal of Food Science 80:2 (2015), E359–E369.
13. Lee, S.J., McClements, D.J., Fabrication of protein-stabilized nanoemulsions using a combined homogenization and amphiphilic solvent dissolution/evaporation approach. Food Hydrocolloids 24 (2010), 560–569.
14. Lee, S.J., Wong, M., Nano- and microencapsulation of phytochemicals. Kwak, H.S., (eds.) Nano- and microencapsulation for foods, 2014, John Wiley & Sons, Ltd, West Sussex, UK, 119–165.
15. Li, D.J., Song, J.F., Liu, C.Q., Kinetic stability of lutein in freeze-dried sweet corn powder stored under different conditions. Food Science and Technology Research 20:1 (2014), 65–70.
16. Lim, A.S.L., Griffin, C., Roos, Y.H., Stability and loss kinetics of lutein and β-carotene encapsulated in freeze-dried emulsions with layered interface and trehalose as glass former. Food Research International 62 (2014), 403–409.
17. Lin, C.C., Lin, H.Y., Chi, M.H., Shen, C.M., Chen, H.W., Yang, W.J., Lee, M.H., Preparation of curcumin microemulsions with food-grade soybean oil/lecithin and their cytotoxicity on the HepG2 cell line. Food Chemistry 154 (2014), 282–290.
18. Luo, Y., Chen, D., Ren, L., Zhao, X., Qin, J., Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability. Journal of Controlled Release 114:1 (2006), 53–59.
19. McClements, D.J., Food emulsions principles, practices, and techniques. 1999, CRC Press, Boca Raton, FL.
20. McClements, D.J., Xiao, H., Potential biological fate of ingested nanoemulsions: Influence of particle characteristics. Food & Function 3:3 (2012), 202–220.
21. Mizrahi, S., Accelerated shelf life testing of foods. Kilcast, D., Subramaniam, P., (eds.) Food and beverage stability and life, 2011, Woodhead Publishing Limited, Cambridge, 482–506.
22. Namitha, K.K., Negi, P.S., Chemistry and biotechnology of carotenoids. Critical Reviews in Food Science and Nutrition 50 (2010), 728–760.
23. Qian, C., Decker, E.A., Xiao, H., McClements, D.J., Physical and chemical stability of β-carotene-enriched nanoemulsions: Influence of pH, ionic strength, temperature, and emulsifier type. Food Chemistry 132:3 (2012), 1221–1229.
24. Reboul, E., Absorption of vitamin A and carotenoids by the enterocyte: Focus on transport proteins. Nutrients 5:9 (2013), 3563–3581.
25. Reboul, E., Abou, L., Mika, C., Ghiringhelli, O., André, M., Portugal, H.,. Borel, P., Lutein transport by Caco-2 TC-7 cells occurs partly by a facilitated process involving the scavenger receptor class B type 1 (SR-B1). Biochemical Society 387:2 (2005), 455–461.
26. Ribaya-Mercado, J.D., Blumberg, J.B., Lutein and Zeaxanthin and their potential roles in disease prevention. Journal of the American College of Nutrition 23:6 (2004), 567S–587S.
27. Sah, B.N.P., Vasiljevic, T., McKechnie, S., Donkor, O.N., Identification of anticancer peptides from bovine milk proteins and their potential roles in management of cancer: A critical review. Comprehensive Reviews in Food Science and Food Safety 14:2 (2015), 123–138.
28. Seddon, J.M., Ajani, U.A., Sperduto, R.D., Hiller, R., Blair, N., Burton, T.C.,. Miller, D.T., Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye disease case-control study group. Journal of the American Medical Association 272:18 (1994), 1413–1420.
29. Shegokar, R., Mitri, K., Carotenoid lutein: A promising candidate for pharmaceutical and nutraceutical applications. Journal of Dietary Supplements 9:3 (2012), 183–210.
30. Stephenson, R.J., Wolber, F., Plieger, P.G., Harding, D.R.K., Synthesis and characterization of bradykinin derivatives based on a beta-cyclodextrin core. Australian Journal of Chemistry 69:3 (2016), 328–335.
31. Tan, C.P., Nakajima, M., β-Carotene nanodispersions: Preparation, characterization and stability evaluation. Food Chemistry 92:4 (2005), 661–671.
32. Tang, Y.C., Chen, B.H., Pigment change of freeze-dried carotenoid powder during storage. Food Chemistry 69:1 (2000), 11–17.
33. Teo, A., Goh, K.K.T., Wen, J.Y., Oey, I., Ko, S., Kwak, H.S., Lee, S.J., Physicochemical properties of whey protein, lactoferrin and Tween 20 stabilised nanoemulsions: Effect of temperature, pH and salt. Food Chemistry 197 (Part A) (2016), 297–306.
34. Xiao, R., Badger, T.M., Simmen, F.A., Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis. Molecular Cancer 4 (2005), 1–17.
35. Yi, J., Lam, T.I., Yokoyama, W., Cheng, L.W., Zhong, F., Cellular uptake of β-carotene from protein stabilized solid lipid nanoparticles prepared by homogenization-evaporation method. Journal of Agricultural and Food Chemistry 62:5 (2014), 1096–1104.
36. Yu, H., Huang, Q., Investigation of the cytotoxicity of food-grade nanoemulsions in Caco-2 cell monolayers and HepG2 cells. Food Chemistry 141:1 (2013), 29–33.
37. Zhang, J., Field, C.J., Vine, D., Chen, L., Intestinal uptake and transport of vitamin B12-loaded soy protein nanoparticles. Pharmaceutical Research 32:4 (2015), 1288–1303.