-
2
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
3
-
-
0347479287
-
Initial tumor stage and grade as a predictive factor for recurrence in patients with stage T1 grade 3 bladder cancer
-
Kwak C, Ku JH, Park JY, Lee E, Lee SE and Lee C: Initial tumor stage and grade as a predictive factor for recurrence in patients with stage T1 grade 3 bladder cancer. J Urol 171: 149-152, 2004.
-
(2004)
J Urol
, vol.171
, pp. 149-152
-
-
Kwak, C.1
Ku, J.H.2
Park, J.Y.3
Lee, E.4
Lee, S.E.5
Lee, C.6
-
4
-
-
0024817806
-
Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse
-
Sternberg CN, Yagoda A, Scher HI, Watson RC, Geller N, Herr HW, Morse MJ, Sogani PC, Vaughan ED, BanderN, et al: Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse. Cancer 64: 2448-2458, 1989.
-
(1989)
Cancer
, vol.64
, pp. 2448-2458
-
-
Sternberg, C.N.1
Yagoda, A.2
Scher, H.I.3
Watson, R.C.4
Geller, N.5
Herr, H.W.6
Morse, M.J.7
Sogani, P.C.8
Vaughan, E.D.9
Bander, N.10
-
5
-
-
0031010028
-
Persistent DNA damage inhibits S-phase and G2 progression and results in apoptosis
-
Orren DK, Petersen LN and Bohr VA: Persistent DNA damage inhibits S-phase and G2 progression and results in apoptosis. Mol Biol Cell 8: 1129-1142, 1997.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1129-1142
-
-
Orren, D.K.1
Petersen, L.N.2
Bohr, V.A.3
-
6
-
-
0032959825
-
Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic-acid derivative, TAC-101, in human pancreatic-cancer cells
-
Fujimoto K, Hosotani R, Doi R, Wada M, Lee JU, Koshiba T, Miyamoto Y, Tsuji S, Nakajima S and Imamura M: Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic-acid derivative, TAC-101, in human pancreatic-cancer cells. Int J Cancer 81: 637-644, 1999.
-
(1999)
Int J Cancer
, vol.81
, pp. 637-644
-
-
Fujimoto, K.1
Hosotani, R.2
Doi, R.3
Wada, M.4
Lee, J.U.5
Koshiba, T.6
Miyamoto, Y.7
Tsuji, S.8
Nakajima, S.9
Imamura, M.10
-
7
-
-
0034162822
-
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells
-
Gamet-Payrastre L, Li P, Lumeau S, Cassar G, Dupont MA, Chevolleau S, Gasc N, Tulliez J and Tercé F: Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res 60: 1426-1433, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 1426-1433
-
-
Gamet-Payrastre, L.1
Li, P.2
Lumeau, S.3
Cassar, G.4
Dupont, M.A.5
Chevolleau, S.6
Gasc, N.7
Tulliez, J.8
Tercé, F.9
-
8
-
-
0034610743
-
Caspase-l2 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA and Yuan J: Caspase-l2 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103, 2000.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
9
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DiABLO regulates caspase activity and apoptosis
-
Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y and Alnemri ES: A conserved XIAP-interaction motif in caspase-9 and Smac/DiABLO regulates caspase activity and apoptosis. Nature 409: 112-116, 2001.
-
(2001)
Nature
, vol.409
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.S.11
-
11
-
-
36549070757
-
Therapeutic targeting of apoptosis pathways in cancer
-
Ziegler DS and Kung AL: Therapeutic targeting of apoptosis pathways in cancer. Curr Opin Oncol 20: 97-103, 2008.
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 97-103
-
-
Ziegler, D.S.1
Kung, A.L.2
-
12
-
-
0028163714
-
Strategies for the discovery of secondary metabolites from marine bacteria: Ecological perspectives
-
Jensen PR and Fenical W: Strategies for the discovery of secondary metabolites from marine bacteria: Ecological perspectives. Annu Rev Microbiol 48: 559-584, 1994.
-
(1994)
Annu Rev Microbiol
, vol.48
, pp. 559-584
-
-
Jensen, P.R.1
Fenical, W.2
-
13
-
-
0035137292
-
Marine natural products
-
Faulkner DJ: Marine natural products. Nat Prod Rep 18: 1-49, 2001.
-
(2001)
Nat Prod Rep
, vol.18
, pp. 1-49
-
-
Faulkner, D.J.1
-
14
-
-
21244491657
-
2-Pyrone natural products and mimetics: Isolation, characterisation and biological activity
-
McGlacken GP and Fairlamb IJ: 2-Pyrone natural products and mimetics: Isolation, characterisation and biological activity. Nat Prod Rep 22: 369-385, 2005.
-
(2005)
Nat Prod Rep
, vol.22
, pp. 369-385
-
-
McGlacken, G.P.1
Fairlamb, I.J.2
-
15
-
-
0027345554
-
Microbial pyran-2-ones and dihydropyran-2-ones
-
Dickinson JM: Microbial pyran-2-ones and dihydropyran-2-ones. Nat Prod Rep 10: 71-98, 1993.
-
(1993)
Nat Prod Rep
, vol.10
, pp. 71-98
-
-
Dickinson, J.M.1
-
16
-
-
10544246488
-
Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors
-
Thaisrivongs S, Romero DL, Tommasi RA, Janakiraman MN, Strohbach JW, Turner SR, Biles C, Morge RR, Johnson PD, Aristoff PA, et al: Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors. J Med Chem 39: 4630-4642, 1996.
-
(1996)
J Med Chem
, vol.39
, pp. 4630-4642
-
-
Thaisrivongs, S.1
Romero, D.L.2
Tommasi, R.A.3
Janakiraman, M.N.4
Strohbach, J.W.5
Turner, S.R.6
Biles, C.7
Morge, R.R.8
Johnson, P.D.9
Aristoff, P.A.10
-
17
-
-
0030895692
-
Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor
-
Poppe SM, Slade DE, Chong KT, Hinshaw RR, Pagano PJ, Markowitz M, Ho DD, Mo H, Gorman RR III, Dueweke TJ, et al: Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor. Antimicrob Agents Chemother 41: 1058-1063, 1997.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 1058-1063
-
-
Poppe, S.M.1
Slade, D.E.2
Chong, K.T.3
Hinshaw, R.R.4
Pagano, P.J.5
Markowitz, M.6
Ho, D.D.7
Mo, H.8
Gorman, R.R.9
Dueweke, T.J.10
-
18
-
-
12944322516
-
Tipranavir (PNU-140690): A potent, orally bioavailable nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide class
-
Turner SR, Strohbach JW, Tommasi RA, Aristoff PA, Johnson PD, Skulnick HI, Dolak LA, Seest EP, Tomich PK, Bohanon MJ, et al: Tipranavir (PNU-140690): A potent, orally bioavailable nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide class. J Med Chem 41: 3467-3476, 1998.
-
(1998)
J Med Chem
, vol.41
, pp. 3467-3476
-
-
Turner, S.R.1
Strohbach, J.W.2
Tommasi, R.A.3
Aristoff, P.A.4
Johnson, P.D.5
Skulnick, H.I.6
Dolak, L.A.7
Seest, E.P.8
Tomich, P.K.9
Bohanon, M.J.10
-
19
-
-
51749088156
-
Redox regulation of cell survival
-
Trachootham D, Lu W, Ogasawara MA, Nilsa RD and Huang P: Redox regulation of cell survival. Antioxid Redox Signal 10: 1343-1374, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1343-1374
-
-
Trachootham, D.1
Lu, W.2
Ogasawara, M.A.3
Nilsa, R.D.4
Huang, P.5
-
20
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH and Weinert TA: Checkpoints: Controls that ensure the order of cell cycle events. Science 246: 629-634, 1989.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
21
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams JM and Cory S: The Bcl-2 protein family: Arbiters of cell survival. Science 281: 1322-1326, 1998.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
23
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen GS and Dixit VM: Caspases: Intracellular signaling by proteolysis. Cell 91: 443-446, 1997.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
24
-
-
34547807709
-
Molecular biology of cantharidin in cancer cells
-
Rauh R, Kahl S, Boechzelt H, Bauer R, Kaina B and Efferth T: Molecular biology of cantharidin in cancer cells. Chin Med 2: 8, 2007.
-
(2007)
Chin Med
, vol.2
, pp. 8
-
-
Rauh, R.1
Kahl, S.2
Boechzelt, H.3
Bauer, R.4
Kaina, B.5
Efferth, T.6
-
25
-
-
34748858784
-
Oxidative stress and apoptosis: Impact on cancer therapy
-
Ozben T: Oxidative stress and apoptosis: Impact on cancer therapy. J Pharm Sci 96: 2181-2196, 2007.
-
(2007)
J Pharm Sci
, vol.96
, pp. 2181-2196
-
-
Ozben, T.1
-
26
-
-
70350389704
-
ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 upregulation and JNK
-
Xiao L, Eto M and Kazanietz MG: ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 upregulation and JNK. J Biol Chem 284: 29365-29375, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 29365-29375
-
-
Xiao, L.1
Eto, M.2
Kazanietz, M.G.3
-
27
-
-
72049088250
-
Naphtho [1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation
-
Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS and Lin SR: Naphtho [1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation. Toxicol In Vitro 24: 61-70, 2010.
-
(2010)
Toxicol in Vitro
, vol.24
, pp. 61-70
-
-
Lin, K.L.1
Su, J.C.2
Chien, C.M.3
Tseng, C.H.4
Chen, Y.L.5
Chang, L.S.6
Lin, S.R.7
-
28
-
-
70249086563
-
Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in HL299 human lung cancer cells
-
Choi YJ, Kim SY, Oh JM and Juhnn YS: Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in HL299 human lung cancer cells. Exp Mol Med 41: 592-600, 2009.
-
(2009)
Exp Mol Med
, vol.41
, pp. 592-600
-
-
Choi, Y.J.1
Kim, S.Y.2
Oh, J.M.3
Juhnn, Y.S.4
-
29
-
-
77949891272
-
Effects of UVA on TNF-αlpha, IL-1beta, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor
-
An L, Dong GQ, Gao Q, Zhang Y, Hu LW, Li JH and Liu Y: Effects of UVA on TNF-αlpha, IL-1beta, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor. Photodermatol Photoimmunol Photomed 26: 28-35, 2010.
-
(2010)
Photodermatol Photoimmunol Photomed
, vol.26
, pp. 28-35
-
-
An, L.1
Dong, G.Q.2
Gao, Q.3
Zhang, Y.4
Hu, L.W.5
Li, J.H.6
Liu, Y.7
|