Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells

Experimental and Molecular Medicine

Volumn 41, Issue 8, 2009, Pages 592-600

  Choi, Yoon Jung ^a   Kim, So Young ^a   Oh, Jung Min ^a   Juhnn, Yong Sung ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Apoptosis; Bcl 2 homologous antagonist killer protein; Cyclic AMP; G protein coupled; Gamma rays; Heterotrimeric GTP binding protein; Receptors

Indexed keywords

CASPASE 3; CRE RECOMBINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LUCIFERASE; MESSENGER RNA; MUTANT PROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROSTAGLANDIN E2; PROSTANOID RECEPTOR; PROTEIN BAK; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR AP 1;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GAMMA RADIATION; HUMAN; HUMAN CELL; LUNG CANCER; MOLECULAR MECHANICS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GAMMA RAYS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LUNG; LUNG NEOPLASMS; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 70249086563     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.8.065     Document Type: Article

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