Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic- acid derivative, TAC-101, in human pancreatic-cancer cells

International Journal of Cancer

Volumn 81, Issue 4, 1999, Pages 637-644

  Fujimoto, Koji ^a   Hosotani, Ryo ^a   Doi, Ryuichiro ^a   Wada, Michihiko ^a   Lee, Jeon Uk ^a   Koshiba, Takatomo ^a   Miyamoto, Yoshiharu ^a   Tsuji, Shoichiro ^a   Nakajima, Sanae ^a   Imamura, Masayuki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [3,5 BIS(TRIMETHYLSILYL)BENZAMIDE]; 4 [3,5 BIS(TRIMETHYLSILYL)BENZAMIDO]BENZOIC ACID; BENZOIC ACID DERIVATIVE; CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P21; PROTEIN P27; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL CYCLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOATES; CELL CYCLE; CELL DIVISION; CELL NUCLEUS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KINETICS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, RETINOIC ACID; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRETINOIN; TRIMETHYLSILYL COMPOUNDS; TUMOR CELLS, CULTURED;

EID: 0032959825     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990517)81:4<637::AID-IJC21>3.0.CO;2-4     Document Type: Article

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