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Volumn 595, Issue 2, 2017, Pages 489-503

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

Author keywords

ageing; gut brain axis; stress

Indexed keywords

TRYPTOPHAN;

EID: 85006340468     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP273106     Document Type: Article
Times cited : (548)

References (164)
  • 1
    • 84904459295 scopus 로고    scopus 로고
    • A possible link of gut microbiota alteration in type 2 diabetes and Alzheimer's disease pathogenicity: an update
    • Alam MZ, Alam Q, Kamal MA, Abuzenadah AM & Haque A (2014). A possible link of gut microbiota alteration in type 2 diabetes and Alzheimer's disease pathogenicity: an update. CNS Neurol Disord Drug Targets 13, 383–390.
    • (2014) CNS Neurol Disord Drug Targets , vol.13 , pp. 383-390
    • Alam, M.Z.1    Alam, Q.2    Kamal, M.A.3    Abuzenadah, A.M.4    Haque, A.5
  • 2
    • 84945289175 scopus 로고    scopus 로고
    • Use of germ-free animal models in microbiota-related research
    • Al-Asmakh M & Zadjali F (2015). Use of germ-free animal models in microbiota-related research. J Microbiol Biotechnol 25, 1583–1588.
    • (2015) J Microbiol Biotechnol , vol.25 , pp. 1583-1588
    • Al-Asmakh, M.1    Zadjali, F.2
  • 3
    • 84927668122 scopus 로고    scopus 로고
    • Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus
    • Allin KH, Nielsen T & Pedersen O (2015). Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus. Eur J Endocrinol 172, R167–R177.
    • (2015) Eur J Endocrinol , vol.172 , pp. R167-R177
    • Allin, K.H.1    Nielsen, T.2    Pedersen, O.3
  • 4
    • 84969504890 scopus 로고    scopus 로고
    • Human microbiota-associated mice: a model with challenges
    • Arrieta MC, Walter J, Finlay BB (2016). Human microbiota-associated mice: a model with challenges. Cell Host Microbe 19, 575–578.
    • (2016) Cell Host Microbe , vol.19 , pp. 575-578
    • Arrieta, M.C.1    Walter, J.2    Finlay, B.B.3
  • 6
    • 0031890006 scopus 로고    scopus 로고
    • Brain-gut axis in health and disease
    • Aziz Q & Thompson DG (1998). Brain-gut axis in health and disease. Gastroenterology 114, 559–578.
    • (1998) Gastroenterology , vol.114 , pp. 559-578
    • Aziz, Q.1    Thompson, D.G.2
  • 16
    • 84907487932 scopus 로고    scopus 로고
    • The microbiome revolution
    • Blaser MJ (2014). The microbiome revolution. J Clin Invest 124, 4162–4165.
    • (2014) J Clin Invest , vol.124 , pp. 4162-4165
    • Blaser, M.J.1
  • 17
    • 84940662313 scopus 로고    scopus 로고
    • Host biology in light of the microbiome: Ten principles of holobionts and hologenomes
    • Bordenstein SR & Theis KR (2015). Host biology in light of the microbiome: Ten principles of holobionts and hologenomes. PLoS Biol 13, e1002226.
    • (2015) PLoS Biol , vol.13
    • Bordenstein, S.R.1    Theis, K.R.2
  • 22
    • 84941879755 scopus 로고    scopus 로고
    • Short-chain fatty acids in control of body weight and insulin sensitivity
    • Canfora EE, Jocken JW & Blaak EE (2015). Short-chain fatty acids in control of body weight and insulin sensitivity. Nat Rev Endocrinol 11, 577–591.
    • (2015) Nat Rev Endocrinol , vol.11 , pp. 577-591
    • Canfora, E.E.1    Jocken, J.W.2    Blaak, E.E.3
  • 24
    • 84905749423 scopus 로고    scopus 로고
    • Learning about oxytocin: pharmacologic and behavioral issues
    • Chini B, Leonzino M, Braida D & Sala M (2014). Learning about oxytocin: pharmacologic and behavioral issues. Biol Psychiatry 76, 360–366.
    • (2014) Biol Psychiatry , vol.76 , pp. 360-366
    • Chini, B.1    Leonzino, M.2    Braida, D.3    Sala, M.4
  • 31
    • 84867845255 scopus 로고    scopus 로고
    • The interplay between the intestinal microbiota and the brain
    • Collins SM, Surette M & Bercik P (2012). The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol 10, 735–742.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 735-742
    • Collins, S.M.1    Surette, M.2    Bercik, P.3
  • 32
    • 84861992014 scopus 로고    scopus 로고
    • The application of ecological theory toward an understanding of the human microbiome
    • Costello EK, Stagaman K, Dethlefsen L, Bohannan BJ & Relman DA (2012). The application of ecological theory toward an understanding of the human microbiome. Science 336, 1255–1262.
    • (2012) Science , vol.336 , pp. 1255-1262
    • Costello, E.K.1    Stagaman, K.2    Dethlefsen, L.3    Bohannan, B.J.4    Relman, D.A.5
  • 33
    • 84940897790 scopus 로고    scopus 로고
    • Gut microbiota: Microbiota and neuroimmune signalling – Metchnikoff to microglia
    • Cryan JF & Dinan TG (2015). Gut microbiota: Microbiota and neuroimmune signalling – Metchnikoff to microglia. Nat Rev Gastroenterol Hepatol 12, 494–496.
    • (2015) Nat Rev Gastroenterol Hepatol , vol.12 , pp. 494-496
    • Cryan, J.F.1    Dinan, T.G.2
  • 35
    • 84885135911 scopus 로고    scopus 로고
    • Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat
    • Davey KJ, Cotter PD, O'Sullivan O, Crispie F, Dinan TG, Cryan JF & O'Mahony SM (2013). Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat. Transl Psychiatry 3, e309.
    • (2013) Transl Psychiatry , vol.3
    • Davey, K.J.1    Cotter, P.D.2    O'Sullivan, O.3    Crispie, F.4    Dinan, T.G.5    Cryan, J.F.6    O'Mahony, S.M.7
  • 37
    • 84904337496 scopus 로고    scopus 로고
    • The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both
    • De Palma G, Collins SM, Bercik P & Verdu EF (2014). The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both? J Physiol 592, 2989–2997.
    • (2014) J Physiol , vol.592 , pp. 2989-2997
    • De Palma, G.1    Collins, S.M.2    Bercik, P.3    Verdu, E.F.4
  • 40
    • 53049087266 scopus 로고    scopus 로고
    • The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat
    • Desbonnet L, Garrett L, Clarke G, Bienenstock J & Dinan TG (2008). The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat. J Psychiatr Res 43, 164–174.
    • (2008) J Psychiatr Res , vol.43 , pp. 164-174
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3    Bienenstock, J.4    Dinan, T.G.5
  • 43
    • 84927177716 scopus 로고    scopus 로고
    • Genomics of schizophrenia: time to consider the gut microbiome
    • Dinan TG, Borre YE & Cryan JF (2014). Genomics of schizophrenia: time to consider the gut microbiome? Mol Psychiatry 19, 1252–1257.
    • (2014) Mol Psychiatry , vol.19 , pp. 1252-1257
    • Dinan, T.G.1    Borre, Y.E.2    Cryan, J.F.3
  • 46
    • 84920563271 scopus 로고    scopus 로고
    • Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP
    • Distrutti E, O'Reilly JA, McDonald C, Cipriani S, Renga B, Lynch MA & Fiorucci S (2014). Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP. PLoS One 9, e106503.
    • (2014) PLoS One , vol.9
    • Distrutti, E.1    O'Reilly, J.A.2    McDonald, C.3    Cipriani, S.4    Renga, B.5    Lynch, M.A.6    Fiorucci, S.7
  • 47
    • 84957848045 scopus 로고    scopus 로고
    • Peripheral aetiopathogenic drivers and mediators of Parkinson's disease and co-morbidities: role of gastrointestinal microbiota
    • Dobbs SM, Dobbs RJ, Weller C, Charlett A, Augustin A, Taylor D, Ibrahim MA & Bjarnason I (2016). Peripheral aetiopathogenic drivers and mediators of Parkinson's disease and co-morbidities: role of gastrointestinal microbiota. J Neurovirol 22, 22–32.
    • (2016) J Neurovirol , vol.22 , pp. 22-32
    • Dobbs, S.M.1    Dobbs, R.J.2    Weller, C.3    Charlett, A.4    Augustin, A.5    Taylor, D.6    Ibrahim, M.A.7    Bjarnason, I.8
  • 50
    • 84899699114 scopus 로고    scopus 로고
    • Immune modulation of the brain-gut-microbiota axis
    • El Aidy S, Dinan TG, Cryan JF (2014). Immune modulation of the brain-gut-microbiota axis. Front Microbiol 5, 146.
    • (2014) Front Microbiol , vol.5 , pp. 146
    • El Aidy, S.1    Dinan, T.G.2    Cryan, J.F.3
  • 51
    • 84930278414 scopus 로고    scopus 로고
    • Gut microbiota: The conductor in the orchestra of immune-neuroendocrine communication
    • El Aidy S, Dinan TG & Cryan JF (2015). Gut microbiota: The conductor in the orchestra of immune-neuroendocrine communication. Clin Ther 37, 954–967.
    • (2015) Clin Ther , vol.37 , pp. 954-967
    • El Aidy, S.1    Dinan, T.G.2    Cryan, J.F.3
  • 52
    • 84898009140 scopus 로고    scopus 로고
    • Probiotic ‘glow of health’: it's more than skin deep
    • Erdman SE & Poutahidis T (2014). Probiotic ‘glow of health’: it's more than skin deep. Benef Microbes 5, 109–119.
    • (2014) Benef Microbes , vol.5 , pp. 109-119
    • Erdman, S.E.1    Poutahidis, T.2
  • 55
    • 84893370250 scopus 로고    scopus 로고
    • Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice
    • Faith JJ, Ahern PP, Ridaura VK, Cheng J & Gordon JI (2014). Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice. Sci Transl Med 6, 220ra11.
    • (2014) Sci Transl Med , vol.6 , pp. 220ra11
    • Faith, J.J.1    Ahern, P.P.2    Ridaura, V.K.3    Cheng, J.4    Gordon, J.I.5
  • 57
    • 84866437998 scopus 로고    scopus 로고
    • Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications
    • Fasano A (2012). Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol 10, 1096–1100.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 1096-1100
    • Fasano, A.1
  • 59
    • 84979284365 scopus 로고    scopus 로고
    • Gut microbiota and brain function: An evolving field in neuroscience
    • Foster JA, Lyte M, Meyer E & Cryan JF (2016). Gut microbiota and brain function: An evolving field in neuroscience. Int J Neuropsychopharmacol 19, pyv114.
    • (2016) Int J Neuropsychopharmacol , vol.19 , pp. pyv114
    • Foster, J.A.1    Lyte, M.2    Meyer, E.3    Cryan, J.F.4
  • 61
    • 84915796530 scopus 로고    scopus 로고
    • The gut microbiome and the brain
    • Galland L (2014). The gut microbiome and the brain. J Med Food 17, 1261–1272.
    • (2014) J Med Food , vol.17 , pp. 1261-1272
    • Galland, L.1
  • 62
    • 84909606798 scopus 로고    scopus 로고
    • Microbiota-gut-brain axis and cognitive function
    • Gareau MG (2014). Microbiota-gut-brain axis and cognitive function. Adv Exp Med Biol 817, 357–371.
    • (2014) Adv Exp Med Biol , vol.817 , pp. 357-371
    • Gareau, M.G.1
  • 65
    • 70449314486 scopus 로고
    • The germfree animal as a research tool
    • Glimstedt G (1959). The germfree animal as a research tool. Ann N Y Acad Sci 78, 281–284.
    • (1959) Ann N Y Acad Sci , vol.78 , pp. 281-284
    • Glimstedt, G.1
  • 66
    • 84922016335 scopus 로고    scopus 로고
    • Diversity and composition of the adult fecal microbiome associated with history of cesarean birth or appendectomy: Analysis of the American Gut Project
    • Goedert JJ, Hua X, Yu G & Shi J (2014). Diversity and composition of the adult fecal microbiome associated with history of cesarean birth or appendectomy: Analysis of the American Gut Project. EBioMedicine 1, 167–172.
    • (2014) EBioMedicine , vol.1 , pp. 167-172
    • Goedert, J.J.1    Hua, X.2    Yu, G.3    Shi, J.4
  • 67
    • 84883475143 scopus 로고    scopus 로고
    • Review article: small intestinal bacterial overgrowth – prevalence, clinical features, current and developing diagnostic tests, and treatment
    • Grace E, Shaw C, Whelan K & Andreyev HJ (2013). Review article: small intestinal bacterial overgrowth – prevalence, clinical features, current and developing diagnostic tests, and treatment. Aliment Pharmacol Ther 38, 674–688.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 674-688
    • Grace, E.1    Shaw, C.2    Whelan, K.3    Andreyev, H.J.4
  • 69
    • 84901361574 scopus 로고    scopus 로고
    • Germ-free mice as a model to study effect of gut microbiota on host physiology
    • Grover M & Kashyap PC (2014). Germ-free mice as a model to study effect of gut microbiota on host physiology. Neurogastroenterol Motil 26, 745–748.
    • (2014) Neurogastroenterol Motil , vol.26 , pp. 745-748
    • Grover, M.1    Kashyap, P.C.2
  • 70
    • 84941015869 scopus 로고
    • Germ-free rearing of rats
    • Gustafsson B (1946). Germ-free rearing of rats. Acta Anat (Basel) 2, 376–391.
    • (1946) Acta Anat (Basel) , vol.2 , pp. 376-391
    • Gustafsson, B.1
  • 72
    • 84929655273 scopus 로고    scopus 로고
    • Targeting gut microbiota as a possible therapy for diabetes
    • He C, Shan Y & Song W (2015). Targeting gut microbiota as a possible therapy for diabetes. Nutr Res 35, 361–367.
    • (2015) Nutr Res , vol.35 , pp. 361-367
    • He, C.1    Shan, Y.2    Song, W.3
  • 73
    • 84933565982 scopus 로고    scopus 로고
    • MICROBIOTA. Mother's littlest helpers
    • Hinde K & Lewis ZT (2015). MICROBIOTA. Mother's littlest helpers. Science 348, 1427–1428.
    • (2015) Science , vol.348 , pp. 1427-1428
    • Hinde, K.1    Lewis, Z.T.2
  • 76
    • 84923163629 scopus 로고    scopus 로고
    • From circuits to behaviour in the amygdala
    • Janak PH & Tye KM (2015). From circuits to behaviour in the amygdala. Nature 517, 284–292.
    • (2015) Nature , vol.517 , pp. 284-292
    • Janak, P.H.1    Tye, K.M.2
  • 79
    • 84876913132 scopus 로고    scopus 로고
    • Role of the gut microbiota in immunity and inflammatory disease
    • Kamada N, Seo SU, Chen GY & Nunez G (2013). Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol 13, 321–335.
    • (2013) Nat Rev Immunol , vol.13 , pp. 321-335
    • Kamada, N.1    Seo, S.U.2    Chen, G.Y.3    Nunez, G.4
  • 80
    • 84944446673 scopus 로고    scopus 로고
    • Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
    • Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G & Hyland NP (2015). Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Front Cell Neurosci 9, 392.
    • (2015) Front Cell Neurosci , vol.9 , pp. 392
    • Kelly, J.R.1    Kennedy, P.J.2    Cryan, J.F.3    Dinan, T.G.4    Clarke, G.5    Hyland, N.P.6
  • 83
    • 84971519476 scopus 로고    scopus 로고
    • From dietary fibre to host physiology: short-chain fatty acids as key bacterial metabolites
    • Koh A, De Vadder F, Kovatcheva-Datchary P & Backhed F (2016). From dietary fibre to host physiology: short-chain fatty acids as key bacterial metabolites. Cell 165, 1332–1345.
    • (2016) Cell , vol.165 , pp. 1332-1345
    • Koh, A.1    De Vadder, F.2    Kovatcheva-Datchary, P.3    Backhed, F.4
  • 85
    • 84924594557 scopus 로고    scopus 로고
    • The gut microbiota in internal medicine: implications for health and disease
    • Lankelma JM, Nieuwdorp M, de Vos WM & Wiersinga WJ (2015). The gut microbiota in internal medicine: implications for health and disease. Neth J Med 73, 61–68.
    • (2015) Neth J Med , vol.73 , pp. 61-68
    • Lankelma, J.M.1    Nieuwdorp, M.2    de Vos, W.M.3    Wiersinga, W.J.4
  • 86
    • 84889561670 scopus 로고    scopus 로고
    • Gut microbiota: Please pass the microbes
    • Leach J (2013). Gut microbiota: Please pass the microbes. Nature 504, 33.
    • (2013) Nature , vol.504 , pp. 33
    • Leach, J.1
  • 87
    • 35348858152 scopus 로고    scopus 로고
    • The amygdala
    • LeDoux J (2007). The amygdala. Curr Biol 17, R868–874.
    • (2007) Curr Biol , vol.17 , pp. R868-874
    • LeDoux, J.1
  • 89
    • 84941795860 scopus 로고    scopus 로고
    • Xenobiotics: Interaction with the intestinal microflora
    • Lu K, Mahbub R & Fox JG (2015). Xenobiotics: Interaction with the intestinal microflora. ILAR J 56, 218–227.
    • (2015) ILAR J , vol.56 , pp. 218-227
    • Lu, K.1    Mahbub, R.2    Fox, J.G.3
  • 91
    • 84978215414 scopus 로고    scopus 로고
    • Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus
    • (in press;
    • Luczynski P, Whelan SO, O'Sullivan C, Clarke G, Shanahan F, Dinan TG & Cryan JF (2016b). Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus. Eur J Neurosci (in press; DOI: 10.1111/ejn.13291).
    • (2016) Eur J Neurosci
    • Luczynski, P.1    Whelan, S.O.2    O'Sullivan, C.3    Clarke, G.4    Shanahan, F.5    Dinan, T.G.6    Cryan, J.F.7
  • 92
    • 0346728801 scopus 로고    scopus 로고
    • Long-term potentiation and memory
    • Lynch MA (2004). Long-term potentiation and memory. Physiol Rev 84, 87–136.
    • (2004) Physiol Rev , vol.84 , pp. 87-136
    • Lynch, M.A.1
  • 94
    • 84888217565 scopus 로고    scopus 로고
    • Microbial endocrinology in the microbiome-gut-brain axis: how bacterial production and utilization of neurochemicals influence behavior
    • Lyte M (2013). Microbial endocrinology in the microbiome-gut-brain axis: how bacterial production and utilization of neurochemicals influence behavior. PLoS Pathog 9, e1003726.
    • (2013) PLoS Pathog , vol.9
    • Lyte, M.1
  • 95
    • 84900836517 scopus 로고    scopus 로고
    • Microbial endocrinology: Host-microbiota neuroendocrine interactions influencing brain and behavior
    • Lyte M (2014). Microbial endocrinology: Host-microbiota neuroendocrine interactions influencing brain and behavior. Gut Microbes 5, 381–389.
    • (2014) Gut Microbes , vol.5 , pp. 381-389
    • Lyte, M.1
  • 96
    • 84899887691 scopus 로고    scopus 로고
    • Recycling Metchnikoff: probiotics, the intestinal microbiome and the quest for long life
    • Mackowiak PA (2013). Recycling Metchnikoff: probiotics, the intestinal microbiome and the quest for long life. Front Public Health 1, 52.
    • (2013) Front Public Health , vol.1 , pp. 52
    • Mackowiak, P.A.1
  • 99
    • 79960645242 scopus 로고    scopus 로고
    • Gut feelings: the emerging biology of gut-brain communication
    • Mayer EA (2011). Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci 12, 453–466.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 453-466
    • Mayer, E.A.1
  • 101
    • 84908152766 scopus 로고    scopus 로고
    • Altered brain-gut axis in autism: comorbidity or causative mechanisms
    • Mayer EA, Padua D & Tillisch K (2014b). Altered brain-gut axis in autism: comorbidity or causative mechanisms? Bioessays 36, 933–939.
    • (2014) Bioessays , vol.36 , pp. 933-939
    • Mayer, E.A.1    Padua, D.2    Tillisch, K.3
  • 103
    • 84930746598 scopus 로고    scopus 로고
    • Parkinson's disease and alpha-synucleinopathies: from arising pathways to therapeutic challenge
    • Miraglia F, Betti L, Palego L & Giannaccini G (2015). Parkinson's disease and alpha-synucleinopathies: from arising pathways to therapeutic challenge. Cent Nerv Syst Agents Med Chem 15, 109–116.
    • (2015) Cent Nerv Syst Agents Med Chem , vol.15 , pp. 109-116
    • Miraglia, F.1    Betti, L.2    Palego, L.3    Giannaccini, G.4
  • 104
    • 84870057403 scopus 로고    scopus 로고
    • Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents
    • Miyamoto S, Miyake N, Jarskog LF, Fleischhacker WW & Lieberman JA (2012). Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents. Mol Psychiatry 17, 1206–1227.
    • (2012) Mol Psychiatry , vol.17 , pp. 1206-1227
    • Miyamoto, S.1    Miyake, N.2    Jarskog, L.F.3    Fleischhacker, W.W.4    Lieberman, J.A.5
  • 105
    • 84856120944 scopus 로고    scopus 로고
    • From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment
    • Moghaddam B & Javitt D (2012). From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment. Neuropsychopharmacology 37, 4–15.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 4-15
    • Moghaddam, B.1    Javitt, D.2
  • 113
    • 79551713705 scopus 로고    scopus 로고
    • Reduced anxiety-like behavior and central neurochemical change in germ-free mice
    • Neufeld KM, Kang N, Bienenstock J & Foster JA (2011). Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterol Motil 23, 255–264, e119.
    • (2011) Neurogastroenterol Motil , vol.23 , pp. 255-264
    • Neufeld, K.M.1    Kang, N.2    Bienenstock, J.3    Foster, J.A.4
  • 114
    • 84920404296 scopus 로고    scopus 로고
    • How informative is the mouse for human gut microbiota research
    • Nguyen TL, Vieira-Silva S, Liston A & Raes J (2015). How informative is the mouse for human gut microbiota research? Dis Model Mech 8, 1–16.
    • (2015) Dis Model Mech , vol.8 , pp. 1-16
    • Nguyen, T.L.1    Vieira-Silva, S.2    Liston, A.3    Raes, J.4
  • 116
    • 84912531587 scopus 로고    scopus 로고
    • A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis
    • O’Leary OF, Cryan JF (2014). A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis. Trends in Pharmacological Sciences 35, 675–687.
    • (2014) Trends in Pharmacological Sciences , vol.35 , pp. 675-687
    • O’Leary, O.F.1    Cryan, J.F.2
  • 117
    • 84862727180 scopus 로고    scopus 로고
    • Rethinking inflammation: neural circuits in the regulation of immunity
    • Olofsson PS, Rosas-Ballina M, Levine YA & Tracey KJ (2012). Rethinking inflammation: neural circuits in the regulation of immunity. Immunol Rev 248, 188–204.
    • (2012) Immunol Rev , vol.248 , pp. 188-204
    • Olofsson, P.S.1    Rosas-Ballina, M.2    Levine, Y.A.3    Tracey, K.J.4
  • 119
    • 84951325446 scopus 로고    scopus 로고
    • Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle
    • (in press;
    • O'Mahony SM, Clarke G, Dinan TG & Cryan JF (2015b). Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle? Neuroscience (in press; DOI: 10.1016/j.neuroscience.2015.09.068).
    • (2015) Neuroscience
    • O'Mahony, S.M.1    Clarke, G.2    Dinan, T.G.3    Cryan, J.F.4
  • 122
    • 58149291318 scopus 로고    scopus 로고
    • Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illesses
    • O'Mahony SM, Marchesi JR, Scully P, Codling C, Ceolho AM, Quigley EM, Cryan JF & Dinan TG (2009). Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illesses. Biol Psychiatry 65, 263–267.
    • (2009) Biol Psychiatry , vol.65 , pp. 263-267
    • O'Mahony, S.M.1    Marchesi, J.R.2    Scully, P.3    Codling, C.4    Ceolho, A.M.5    Quigley, E.M.6    Cryan, J.F.7    Dinan, T.G.8
  • 123
    • 84948992933 scopus 로고    scopus 로고
    • Gut microbiota and aging
    • O'Toole PW & Jeffery IB (2015). Gut microbiota and aging. Science 350, 1214–1215.
    • (2015) Science , vol.350 , pp. 1214-1215
    • O'Toole, P.W.1    Jeffery, I.B.2
  • 126
    • 84920896861 scopus 로고    scopus 로고
    • Investigating the long-term effect of subchronic phencyclidine-treatment on novel object recognition and the association between the gut microbiota and behavior in the animal model of schizophrenia
    • Pyndt Jorgensen B, Krych L, Pedersen TB, Plath N, Redrobe JP, Hansen AK, Nielsen DS, Pedersen CS, Larsen C & Sorensen DB (2015). Investigating the long-term effect of subchronic phencyclidine-treatment on novel object recognition and the association between the gut microbiota and behavior in the animal model of schizophrenia. Physiol Behav 141, 32–39.
    • (2015) Physiol Behav , vol.141 , pp. 32-39
    • Pyndt Jorgensen, B.1    Krych, L.2    Pedersen, T.B.3    Plath, N.4    Redrobe, J.P.5    Hansen, A.K.6    Nielsen, D.S.7    Pedersen, C.S.8    Larsen, C.9    Sorensen, D.B.10
  • 129
    • 67650333217 scopus 로고    scopus 로고
    • Principles and clinical implications of the brain-gut-enteric microbiota axis
    • Rhee SH, Pothoulakis C & Mayer EA (2009). Principles and clinical implications of the brain-gut-enteric microbiota axis. Nat Rev Gastroenterol hepatol 6, 306–314.
    • (2009) Nat Rev Gastroenterol hepatol , vol.6 , pp. 306-314
    • Rhee, S.H.1    Pothoulakis, C.2    Mayer, E.A.3
  • 131
    • 84946224701 scopus 로고    scopus 로고
    • Microbiome disturbances and autism spectrum disorders
    • Rosenfeld CS (2015). Microbiome disturbances and autism spectrum disorders. Drug Metab Dispos 43, 1557–1571.
    • (2015) Drug Metab Dispos , vol.43 , pp. 1557-1571
    • Rosenfeld, C.S.1
  • 132
    • 84929310699 scopus 로고    scopus 로고
    • Control of brain development, function, and behavior by the microbiome
    • Sampson TR & Mazmanian SK (2015). Control of brain development, function, and behavior by the microbiome. Cell Host Microbe 17, 565–576.
    • (2015) Cell Host Microbe , vol.17 , pp. 565-576
    • Sampson, T.R.1    Mazmanian, S.K.2
  • 138
    • 33747064990 scopus 로고    scopus 로고
    • Stereological analysis of amygdala neuron number in autism
    • Schumann CM & Amaral DG (2006). Stereological analysis of amygdala neuron number in autism. J Neurosci 26, 7674–7679.
    • (2006) J Neurosci , vol.26 , pp. 7674-7679
    • Schumann, C.M.1    Amaral, D.G.2
  • 139
    • 84880781872 scopus 로고    scopus 로고
    • The brain-gut axis: a target for treating stress-related disorders
    • Scott LV, Clarke G & Dinan TG (2013). The brain-gut axis: a target for treating stress-related disorders. Mod Trends Pharmacopsychiatri 28, 90–99.
    • (2013) Mod Trends Pharmacopsychiatri , vol.28 , pp. 90-99
    • Scott, L.V.1    Clarke, G.2    Dinan, T.G.3
  • 140
    • 84961288867 scopus 로고    scopus 로고
    • Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans
    • Sender R, Fuchs S & Milo R (2016). Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 164, 337–340.
    • (2016) Cell , vol.164 , pp. 337-340
    • Sender, R.1    Fuchs, S.2    Milo, R.3
  • 141
    • 84938153242 scopus 로고    scopus 로고
    • News feature: Microbes on the mind
    • Shen HH (2015). News feature: Microbes on the mind. Proc Natl Acad Sci USA 112, 9143–9145.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 9143-9145
    • Shen, H.H.1
  • 142
    • 84876414806 scopus 로고    scopus 로고
    • The gut microbiota – masters of host development and physiology
    • Sommer F & Backhed F (2013). The gut microbiota – masters of host development and physiology. Nat Rev Microbiol 11, 227–238.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 227-238
    • Sommer, F.1    Backhed, F.2
  • 143
    • 84961262440 scopus 로고    scopus 로고
    • Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology
    • Sommer F & Backhed F (2016). Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology. Bioessays 38, 455–464.
    • (2016) Bioessays , vol.38 , pp. 455-464
    • Sommer, F.1    Backhed, F.2
  • 145
    • 84867807929 scopus 로고    scopus 로고
    • Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease
    • Sonnenberg GF & Artis D (2012). Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. Immunity 37, 601–610.
    • (2012) Immunity , vol.37 , pp. 601-610
    • Sonnenberg, G.F.1    Artis, D.2
  • 147
  • 148
    • 84891628557 scopus 로고    scopus 로고
    • Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis
    • Stilling RM, Dinan TG & Cryan JF (2014). Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis. Genes Brain Behav 13, 69–86.
    • (2014) Genes Brain Behav , vol.13 , pp. 69-86
    • Stilling, R.M.1    Dinan, T.G.2    Cryan, J.F.3
  • 149
    • 84938150375 scopus 로고    scopus 로고
    • Microbes & neurodevelopment – Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala
    • Stilling RM, Ryan FJ, Hoban AE, Shanahan F, Clarke G, Claesson MJ, Dinan TG & Cryan JF (2015). Microbes & neurodevelopment – Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala. Brain Behav Immun 50, 209–220.
    • (2015) Brain Behav Immun , vol.50 , pp. 209-220
    • Stilling, R.M.1    Ryan, F.J.2    Hoban, A.E.3    Shanahan, F.4    Clarke, G.5    Claesson, M.J.6    Dinan, T.G.7    Cryan, J.F.8
  • 151
    • 4043161248 scopus 로고    scopus 로고
    • Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice
    • Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, Kubo C & Koga Y (2004). Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice. J Physiol 558, 263–275.
    • (2004) J Physiol , vol.558 , pp. 263-275
    • Sudo, N.1    Chida, Y.2    Aiba, Y.3    Sonoda, J.4    Oyama, N.5    Yu, X.N.6    Kubo, C.7    Koga, Y.8
  • 153
    • 84964315352 scopus 로고    scopus 로고
    • The effects of gut microbiota on CNS function in humans
    • Tillisch K (2014). The effects of gut microbiota on CNS function in humans. Gut Microbes 5, 404–410.
    • (2014) Gut Microbes , vol.5 , pp. 404-410
    • Tillisch, K.1
  • 155
    • 84928889245 scopus 로고    scopus 로고
    • Healthy gut microbiota and long term health
    • Vandenplas Y (2015). Healthy gut microbiota and long term health. Benef Microbes 6, 173–179.
    • (2015) Benef Microbes , vol.6 , pp. 173-179
    • Vandenplas, Y.1
  • 156
    • 84907704625 scopus 로고    scopus 로고
    • Diet and the development of the human intestinal microbiome
    • Voreades N, Kozil A & Weir TL (2014). Diet and the development of the human intestinal microbiome. Front Microbiol 5, 494.
    • (2014) Front Microbiol , vol.5 , pp. 494
    • Voreades, N.1    Kozil, A.2    Weir, T.L.3
  • 158
    • 84898542916 scopus 로고    scopus 로고
    • The role of microbiome in central nervous system disorders
    • Wang Y & Kasper LH (2014). The role of microbiome in central nervous system disorders. Brain Behav Immun 38, 1–12.
    • (2014) Brain Behav Immun , vol.38 , pp. 1-12
    • Wang, Y.1    Kasper, L.H.2
  • 159
    • 84953217700 scopus 로고    scopus 로고
    • The infant microbiome: Implications for infant health and neurocognitive development
    • Yang I, Corwin EJ, Brennan PA, Jordan S, Murphy JR & Dunlop A (2016). The infant microbiome: Implications for infant health and neurocognitive development. Nurs Res 65, 76–88.
    • (2016) Nurs Res , vol.65 , pp. 76-88
    • Yang, I.1    Corwin, E.J.2    Brennan, P.A.3    Jordan, S.4    Murphy, J.R.5    Dunlop, A.6
  • 161
    • 84945558237 scopus 로고    scopus 로고
    • The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial
    • Yatawara CJ, Einfeld SL, Hickie IB, Davenport TA & Guastella AJ (2016). The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial. Mol Psychiatry 21, 1225–1231.
    • (2016) Mol Psychiatry , vol.21 , pp. 1225-1231
    • Yatawara, C.J.1    Einfeld, S.L.2    Hickie, I.B.3    Davenport, T.A.4    Guastella, A.J.5
  • 162
    • 84903783240 scopus 로고    scopus 로고
    • Sex differences in neurological and psychiatric disorders
    • Young LJ & Pfaff DW (2014). Sex differences in neurological and psychiatric disorders. Front Neuroendocrinol 35, 253–254.
    • (2014) Front Neuroendocrinol , vol.35 , pp. 253-254
    • Young, L.J.1    Pfaff, D.W.2
  • 163
    • 84928419459 scopus 로고    scopus 로고
    • The microbiota and microbiome in aging: potential implications in health and age-related diseases
    • Zapata HJ & Quagliarello VJ (2015). The microbiota and microbiome in aging: potential implications in health and age-related diseases. J Am Geriatr Soc 63, 776–781.
    • (2015) J Am Geriatr Soc , vol.63 , pp. 776-781
    • Zapata, H.J.1    Quagliarello, V.J.2
  • 164
    • 84989328937 scopus 로고    scopus 로고
    • Functional genomics of human brain development and implications for autism spectrum disorders
    • Ziats MN, Grosvenor LP & Rennert OM (2015). Functional genomics of human brain development and implications for autism spectrum disorders. Transl Psychiatry 5, e665.
    • (2015) Transl Psychiatry , vol.5
    • Ziats, M.N.1    Grosvenor, L.P.2    Rennert, O.M.3


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