Old dog, new tricks: IL-6 cluster signaling promotes pathogenic T H 17 cell differentiation

Nature Immunology

Volumn 18, Issue 1, 2017, Pages 8-10

  Quintana, Francisco J ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 17;

ARTICLE; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; IMMUNOMODULATION; IMMUNOPATHOGENESIS; INTRACELLULAR SIGNALING; LYMPHOCYTE DIFFERENTIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH17 CELL; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DOG; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; DOGS; INTERLEUKIN-17; INTERLEUKIN-6; SIGNAL TRANSDUCTION; TH17 CELLS;

EID: 85006340445     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3637     Document Type: Article

References (15)

1. Bettelli, E. et al. Nature 441, 235-238 (2006).
2. Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. & Stockinger, B. Immunity 24, 179-189 (2006).
3. Heink, S. et al. Nat. Immunol. 18, 74-85 (2017).
4. Boulanger, M. J., Chow, D. C., Brevnova, E. E. & Garcia, K. C. Science 300, 2101-2104 (2003).
5. Hunter, C. A. & Jones, S. A. Nat. Immunol. 16, 448-457 (2015).
6. Tamura, T. et al. Proc. Natl. Acad. Sci. USA 90, 11924-11928 (1993).
7. McGeachy, M. J. et al. Nat. Immunol. 10, 314-324 (2009).
8. Zhou, L. et al. Nat. Immunol. 8, 967-974 (2007).
9. Böttcher, J. P. et al. Cell Rep. 8, 1318-1327 (2014).
10. Nurieva, R. I. et al. Immunity 29, 138-149 (2008).
11. Zheng, Y. et al. Nature 445, 648-651 (2007).
12. Stumhofer, J. S. et al. Nat. Immunol. 8, 1363-1371 (2007).
13. Hegde, S., Pahne, J. & Smola-Hess, S. FASEB J. 18, 1439-1441 (2004).
14. Mascanfroni, I. D. et al. Nat. Med. 21, 638-646 (2015).
15. Yeste, A. et al. Sci. Signal. 9, ra61 (2016).