Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells

Nature Immunology

Volumn 18, Issue 1, 2017, Pages 74-85

  Heink, Sylvia ^a   Yogev, Nir ^b   Garbers, Christoph ^c   Herwerth, Marina ^b   Aly, Lilian ^a   Gasperi, Christiane ^a   Husterer, Veronika ^a   Croxford, Andrew L ^b   Möller Hackbarth, Katja ^c   Bartsch, Harald S ^e   Sotlar, Karl ^e   Krebs, Stefan ^e   Regen, Tommy ^b   Blum, Helmut ^e   Hemmer, Bernhard ^a,f   Misgeld, Thomas ^d,f   Wunderlich, Thomas F ^g   Hidalgo, Juan ^h   Oukka, Mohamed ^i,j   Rose John, Stefan ^c   Schmidt Supprian, Marc ^a   Waisman, Ari ^b   Korn, Thomas ^e,f   more..

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

^f Technische Universität München Munich Cluster for Systems Neurology   (Germany)

^g MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

^h UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

ⁱ UNIVERSITY OF WASHINGTON   (United States)

^j SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD11B ANTIGEN; CD45 ANTIGEN; CRE RECOMBINASE; CYAN FLUORESCENT PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN GP 130; GLYCOPROTEIN P 15095; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ALPHA; LIPOPOLYSACCHARIDE; PROTEIN; SIRPALPHA PROTEIN; STAPHYLOCOCCUS ENTEROTOXIN B; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT; PTPNS1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL INTERACTION; COGNATE INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DENDRITIC CELL; EMBRYO; FLOW CYTOMETRY; HEMATOPOIETIC CELL; IMMUNIZATION; LOXP SITE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; TH17 CELL; UPREGULATION; WILD TYPE; ANIMAL; AUTOIMMUNITY; C57BL MOUSE; CELL CULTURE; CENTRAL NERVOUS SYSTEM; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM;

ANIMALS; AUTOIMMUNITY; CELL DIFFERENTIATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; RECEPTORS, IMMUNOLOGIC; TH17 CELLS;

EID: 84997637138     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3632     Document Type: Article

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