Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism

Nature Communications

Volumn 7, Issue , 2016, Pages

  Mehrmohamadi, Mahya ^a,b,c   Mentch, Lucas K ^c   Clark, Andrew G ^c,d   Locasale, Jason W ^a,b  

^a DUKE CANCER INSTITUTE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

^d Program on Infrastructure Policy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ANDROGEN RECEPTOR; APC PROTEIN; BETAINE HOMOCYSTEINE METHYLTRANSFERASE; DNA; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; ESTROGEN RECEPTOR ALPHA; GLUTATHIONE TRANSFERASE P1; HISTONE METHYLTRANSFERASE; ISOCITRATE DEHYDROGENASE 1; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 2 BETA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1; RAS PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

CANCER; DNA; GENE EXPRESSION; GENETIC ANALYSIS; HETEROGENEITY; METABOLISM; METHYLATION; NUMERICAL MODEL; SURVIVAL; TUMOR;

ALGORITHM; ARTICLE; CANCER GENETICS; CARCINOGENESIS; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA METABOLISM; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC VARIATION; GENOMICS; HUMAN; HUMAN TISSUE; MALE; METABOLISM; NEOPLASM; PROMOTER REGION; TUMOR GENE; BIOLOGICAL MODEL; GENETIC EPIGENESIS; GENETICS; SURVIVAL ANALYSIS;

DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; SURVIVAL ANALYSIS;

EID: 85006051826     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13666     Document Type: Article

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