Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion

European Journal of Pharmacology

Volumn 794, Issue , 2017, Pages 162-172

  Mousslim, Mohamed ^a   Pagano, Alessandra ^a   Andreotti, Nicolas ^b   Garrouste, Françoise ^a   Thuault, Sylvie ^a   Peyrot, Vincent ^a   Parat, Fabrice ^a   Luis, José ^a   Culcasi, Marcel ^c   Thétiot Laurent, Sophie ^c   Pietri, Sylvia ^c   Sabatier, Jean Marc ^b   Kovacic, Hervé ^a  

^a University of the Mediterranean Aix Marseille II   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c AIX MARSEILLE UNIV   (France)

Author keywords

Cell migration; EPR spin trapping; NADPH oxidase; Nox1; Reactive oxygen species; Superoxide

Indexed keywords

ENZYME INHIBITOR; LACTATE DEHYDROGENASE; NF01; NF02; PROTEIN NOXA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; XANTHINE OXIDASE; NOX1 PROTEIN, HUMAN; OLIGOPEPTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; COLORECTAL CANCER CELL LINE; DRUG IDENTIFICATION; DRUG SCREENING; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; SOLID PHASE SYNTHESIS; SPHEROID CELL; SPIN TRAPPING; SUPERNATANT; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL MOTION; CHEMISTRY; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE; TUMOR INVASION;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; NADPH OXIDASE; NEOPLASM INVASIVENESS; OLIGOPEPTIDES;

EID: 85005976179     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.10.011     Document Type: Article

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