Detection of segmental aneuploidy and mosaicism in the human preimplantation embryo: technical considerations and limitations

Fertility and Sterility

Volumn 107, Issue 1, 2017, Pages 27-31

  Treff, Nathan R ^a,b   Franasiak, Jason M ^b  

^a REPRODUCTIVE MEDICINE ASSOCIATES OF NEW JERSEY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Array comparative genomic hybridization; mosaicism; next generation sequencing; segmental aneuploidy; single nucleotide polymorphism microarray

Indexed keywords

ANEUPLOIDY; BIOINFORMATICS; CHROMOSOME ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; HUMAN; MOSAICISM; NEXT GENERATION SEQUENCING; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; REVIEW; SEGMENTAL ANEUPLOIDY; SINGLE NUCLEOTIDE POLYMORPHISM; ADVERSE EFFECTS; BLASTOCYST; CHROMOSOME DISORDERS; DNA MICROARRAY; EMBRYO TRANSFER; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN CHROMOSOME; INFERTILITY THERAPY; PATHOLOGY; PHENOTYPE; PREDICTIVE VALUE; PREGNANCY; PREGNANCY OUTCOME; PREIMPLANTATION GENETIC DIAGNOSIS; PROCEDURES; RISK ASSESSMENT; RISK FACTOR; TREATMENT OUTCOME;

ANEUPLOIDY; BLASTOCYST; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN; COMPARATIVE GENOMIC HYBRIDIZATION; EMBRYO TRANSFER; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MOSAICISM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY OUTCOME; PREIMPLANTATION DIAGNOSIS; REPRODUCTIVE TECHNIQUES, ASSISTED; RISK ASSESSMENT; RISK FACTORS; TREATMENT OUTCOME;

EID: 85005870105     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2016.09.039     Document Type: Review

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