Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: A randomized controlled trial

Fertility and Sterility

Volumn 100, Issue 3, 2013, Pages 697-703

  Scott, Richard T ^a,b   Upham, Kathleen M ^a   Forman, Eric J ^b   Hong, Kathleen H ^b   Scott, Katherine L ^a,c   Taylor, Deanne ^a,b   Tao, Xin ^a   Treff, Nathan R ^a,b  

^a REPRODUCTIVE MEDICINE ASSOCIATES OF NEW JERSEY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c Atlantic Reproductive Medicine   (United States)

Author keywords

blastocyst; comprehensive chromosomal screening; embryonic aneuploidy; IVF; preimplantation genetic screening

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; BIOPSY; BLASTOCYST; CHROMOSOME; CONCEPTION; CONTROLLED STUDY; DELIVERY; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; GENETIC SCREENING; HUMAN; MAJOR CLINICAL STUDY; NIDATION; OOCYTE DONATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION;

EID: 84883453649     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.04.035     Document Type: Article

References (19)

1. Centers for Disease Control and Prevention National summary report assisted reproductive technology (ART) report 2009 Centers for Disease Control and Prevention Atlanta
2. A. Nasseri, T. Mukherjee, J.A. Grifo, N. Noyes, L. Krey, and A.B. Copperman Elevated day 3 serum follicle stimulating hormone and/or estradiol may predict fetal aneuploidy Fertil Steril 71 1999 715 718
3. T. Hassold, and P. Hunt Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew Curr Opin Pediatr 21 2009 703 708
4. M. Werner, A. Reh, J. Grifo, and M.A. Perle Characteristics of chromosomal abnormalities diagnosed after spontaneous abortions in an infertile population J Assist Reprod Genet 29 2012 817 820
5. M.A. Fritz Perspectives on the efficacy and indications for preimplantation genetic screening: where are we now? Hum Reprod 23 2008 2617 2621
6. S. Mastenbroek, M. Twisk, F. van der Veen, and S. Repping Preimplantation genetic screening: a systematic review and meta-analysis of RCTs Hum Reprod Update 17 2011 454 466
7. W.B. Schoolcraft, N.R. Treff, J.M. Stevens, K. Ferry, M. Katz-Jaffe, and R.T. Scott Jr. Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients Fertil Steril 96 2011 638 640
8. E.J. Forman, X. Tao, K.M. Ferry, D. Taylor, N.R. Treff, and R.T. Scott Jr. Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates Hum Reprod 27 2012 1217 1222
9. R.T. Scott Jr., K. Ferry, J. Su, X. Tao, K. Scott, and N.R. Treff Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study Fertil Steril 97 2012 870 875
10. N.R. Treff, X. Tao, K.M. Ferry, J. Su, D. Taylor, and R.T. Scott Jr. Development and validation of an accurate quantitative real-time polymerase chain reaction-based assay for human blastocyst comprehensive chromosomal aneuploidy screening Fertil Steril 97 2012 819 824
11. W.B. Schoolcraft, N.R. Treff, J.M. Stevens, K. Ferry, M. Katz-Jaffe, and R.T. Scott Jr. Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients Fertil Steril 96 2011 638 640
12. R.A. Gross, and K.C. Johnston Levels of evidence: taking neurology to the next level Neurology 72 2009 8 10
13. Z. Pandian, S. Bhattacharya, O. Ozturk, G. Serour, and A. Templeton Number of embryos for transfer following in-vitro fertilisation or intra-cytoplasmic sperm injection Cochrane Database Syst Rev 2 2009 CD003416
14. T.A. Gelbaya, I. Tsoumpou, and L.G. Nardo The likelihood of live birth and multiple birth after single versus double embryo transfer at the cleavage stage: a systematic review and meta-analysis Fertil Steril 94 2010 936 945
15. Practice Committee of American Society for Reproductive Medicine Multiple gestation associated with infertility therapy: an American Society for Reproductive Medicine Practice Committee opinion Fertil Steril 97 2012 825 834
16. M. Niinimaki, A.M. Suikkari, S. Makinen, V. Soderstrom-Anttila, and H. Martikainen Elective single-embryo transfer in women aged 40-44 years Hum Reprod 28 2013 331 335
17. E.J. Forman, K.H. Hong, K.M. Ferry, X. Tao, D. Taylor, and B. Levy In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial Fertil Steril 2013 Epub ahead of print
18. R.T. Scott Jr, K.M. Upham, E.J. Forman, T. Zhao, and N.R. Treff Cleavage stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial Fertil Steril 2013 May 28. doi: 10.1016/j.fertnstert.2013.04.039.
19. M.G. Katz-Jaffe, E.S. Surrey, D.A. Minjarez, R.L. Gustofson, J.M. Stevens, and W.B. Schoolcraft Association of abnormal ovarian reserve parameters with a higher incidence of aneuploid blastocysts Obstet Gynecol 121 2013 71 77