Detection of aneuploidy by array comparative genomic hybridization using cell lines to mimic a mosaic trophectoderm biopsy

Fertility and Sterility

Volumn 97, Issue 4, 2012, Pages 943-947

  Mamas, Thalia ^a   Gordon, Anthony ^b   Brown, Anthony ^b   Harper, Joyce ^a,c   Sengupta, Sioban ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ILLUMINA INC   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

aneuploidy; array CGH; mosaicism; PGS

Indexed keywords

ANEUPLOIDY; ARTICLE; BLASTOCYST; CELL LINE; CHROMOSOMAL INSTABILITY; CHROMOSOME 10; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; ECTODERM; EXPERIMENTAL STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC SCREENING; HUMAN; HUMAN CELL; KARYOTYPE 46,XX; MOSAICISM; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; TROPHECTODERM; X CHROMOSOME;

ANEUPLOIDY; BIOPSY; CELL LINE; CHROMOSOMES, HUMAN; COMPARATIVE GENOMIC HYBRIDIZATION; ECTODERM; FEMALE; GENETIC TESTING; HUMANS; MOSAICISM; PREDICTIVE VALUE OF TESTS; PREIMPLANTATION DIAGNOSIS; TROPHOBLASTS;

EID: 84859161063     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2011.12.048     Document Type: Article

References (10)

1. S. Fishel, A. Gordon, C. Lynch, K. Dowell, G. Ndukwe, and E. Kelada Live birth after polar body array comparative genomic hybridization prediction of embryo ploidy - the future of IVF? Fertil Steril 93 2010 1006.e7 1006.e10
2. C. Gutierrez Mateo, P. Colls, J. Sanchez-Garcia, T. Escudero, R. Prates, and K. Ketterson Validation of comparative genomic hybridization for comprehensive chromosomal analysis of embryos Fertil Steril 95 2011 953 958
3. J.C. Harper, and G. Harton The use of arrays in preimplantation genetic diagnosis and screening Fertil Steril 94 2010 1173 1177
4. J.C. Harper, and J.D.A. Delhanty Detection of chromosomal abnormalities in human preimplatation embryos using FISH J Assist Reprod Genet 13 1996 137 139
5. M. Sandalinas, S. Sadowy, M. Alikani, G. Calderon, J. Cohen, and S. Munné Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage Hum Reprod 16 2001 1954 1958
6. E. Fragouli, M. Lenzi, R. Ross, M. Katz-Jaffe, W.B. Schoolcraft, and D. Wells Comprehensive molecular cytogenetic analysis of the human blastocyst stage Hum Reprod 23 2008 2596 2608
7. L.E. Northrop, N.R. Treff, B. Levy, and R.T. Scott Jr. SNP microarray-based 24 chromosome aneuploidy screening demonstrated that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts Mol Hum Reprod 16 2010 590 600
8. H. Fiegler, J.B. Geigl, S. Langer, D. Rigler, K. Porter, and K. Unger High resolution array-CGH analysis of single cells Nucleic Acids Res 35 2007 e15
9. E. Fragouli, M. Katz-Jaffe, S. Alfarawati, J. Stevens, P. Colls, and N. Goodall Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure Fertil Steril 94 2010 875 887
10. E. Fragouli, S. Alfarawati, D.D. Daphnis, N. Goodall, A. Mania, and T. Griffiths Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation Hum Reprod 26 2011 480 490