Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles

Human Reproduction

Volumn 29, Issue 12, 2014, Pages 2802-2813

  Fiorentino, Francesco ^a   Bono, Sara ^a   Biricik, Anil ^a   Nuccitelli, Andrea ^a   Cotroneo, Ettore ^a   Cottone, Giuliano ^a   Kokocinski, Felix ^b   Michel, Claude Edouard ^b   Minasi, Maria Giulia ^c   Greco, Ermanno ^c  

^a GENOMA Molecular Genetics Laboratory   (Italy)

^b ILLUMINA INC   (United States)

^c EUROPEAN HOSPITAL   (Italy)

Author keywords

array comparative genomic hybridization; clinical outcomes; comprehensive chromosome screening; next generation sequencing; preimplantation genetic screening

Indexed keywords

CHORIONIC GONADOTROPIN; GENOMIC DNA;

ADULT; ANEUPLOIDY; ARTICLE; BIOPSY TECHNIQUE; BLASTOCYST; CHROMOSOME; CHROMOSOME ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOLYSIS; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; FETUS HEART RATE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE AMPLIFICATION; GENETIC SCREENING; HEART BEAT; HUMAN; HUMAN EMBRYO; HUMAN TISSUE; INTRACYTOPLASMIC SPERM INJECTION; KARYOTYPE; KARYOTYPING; MAJOR CLINICAL STUDY; MONOSOMY; NEXT GENERATION SEQUENCING; OUTCOME ASSESSMENT; PARALLEL DESIGN; PATIENT COUNSELING; PATIENT REFERRAL; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PREIMPLANTATION GENETIC SCREENING; SENSITIVITY AND SPECIFICITY; SPONTANEOUS ABORTION; TRISOMY; DNA SEQUENCE; DOUBLE BLIND PROCEDURE; EMBRYO CULTURE; HUMAN GENOME; MIDDLE AGED; PRENATAL DIAGNOSIS; PROCEDURES; VALIDATION STUDY;

ADULT; ANEUPLOIDY; DOUBLE-BLIND METHOD; EMBRYO CULTURE TECHNIQUES; EMBRYO TRANSFER; FEMALE; GENOME, HUMAN; HUMANS; MIDDLE AGED; PREIMPLANTATION DIAGNOSIS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

EID: 84928973006     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu277     Document Type: Article

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