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Volumn 6, Issue 12, 2016, Pages

Enhancing dopaminergic signaling and histone acetylation promotes long-term rescue of deficient fear extinction

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; ENTINOSTAT; LEVODOPA; BENZAMIDE DERIVATIVE; DOPAMINE; HISTONE ACETYLTRANSFERASE; PYRIDINE DERIVATIVE;

EID: 85002778274     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2016.231     Document Type: Article
Times cited : (50)

References (79)
  • 1
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 593-602.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 2
    • 84864533614 scopus 로고    scopus 로고
    • Lifetime co-morbidity of DSM-IV disorders in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A)
    • Kessler RC, Avenevoli S, McLaughlin KA, Green JG, Lakoma MD, Petukhova M et al. Lifetime co-morbidity of DSM-IV disorders in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A). Psychol Med 2012; 42: 1997-2010.
    • (2012) Psychol Med , vol.42 , pp. 1997-2010
    • Kessler, R.C.1    Avenevoli, S.2    McLaughlin, K.A.3    Green, J.G.4    Lakoma, M.D.5    Petukhova, M.6
  • 4
    • 84887257606 scopus 로고    scopus 로고
    • Effective therapies or effective mechanisms in treatment guidelines for depression?
    • Cuijpers P. Effective therapies or effective mechanisms in treatment guidelines for depression? Depress Anxiety 2013; 30: 1055-1057.
    • (2013) Depress Anxiety , vol.30 , pp. 1055-1057
    • Cuijpers, P.1
  • 6
    • 84899839975 scopus 로고    scopus 로고
    • Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology
    • Baldwin DS, Anderson IM, Nutt DJ, Allgulander C, Bandelow B, den Boer JA et al. Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology. J Psycho-pharmacol 2014; 28: 403-439.
    • (2014) J Psycho-pharmacol , vol.28 , pp. 403-439
    • Baldwin, D.S.1    Anderson, I.M.2    Nutt, D.J.3    Allgulander, C.4    Bandelow, B.5    Den Boer, J.A.6
  • 7
    • 33845435806 scopus 로고    scopus 로고
    • Combined pharmacotherapy and cognitive-behavioural therapy for anxiety disorders
    • Pull CB. Combined pharmacotherapy and cognitive-behavioural therapy for anxiety disorders. Curr Opin Psychiatry 2007; 20: 30-35.
    • (2007) Curr Opin Psychiatry , vol.20 , pp. 30-35
    • Pull, C.B.1
  • 8
    • 84871948952 scopus 로고    scopus 로고
    • Predicting treatment response in social anxiety disorder from functional magnetic resonance imaging
    • Doehrmann O, Ghosh SS, Polli FE, Reynolds GO, Horn F, Keshavan A et al. Predicting treatment response in social anxiety disorder from functional magnetic resonance imaging. JAMA Psychiatry 2013; 70: 87-97.
    • (2013) JAMA Psychiatry , vol.70 , pp. 87-97
    • Doehrmann, O.1    Ghosh, S.S.2    Polli, F.E.3    Reynolds, G.O.4    Horn, F.5    Keshavan, A.6
  • 9
    • 84857666179 scopus 로고    scopus 로고
    • Pharmacotherapy of anxiety disorders: A critical review
    • Koen N, Stein DJ. Pharmacotherapy of anxiety disorders: a critical review. Dialogues Clin Neurosci 2011; 13: 423-437.
    • (2011) Dialogues Clin Neurosci , vol.13 , pp. 423-437
    • Koen, N.1    Stein, D.J.2
  • 11
    • 58849146996 scopus 로고    scopus 로고
    • Relapse of successfully treated anxiety and fear: Theoretical issues and recommendations for clinical practice
    • Boschen MJ, Neumann DL, Waters AM. Relapse of successfully treated anxiety and fear: theoretical issues and recommendations for clinical practice. Aust N Z J Psychiatry 2009; 43: 89-100.
    • (2009) Aust N Z J Psychiatry , vol.43 , pp. 89-100
    • Boschen, M.J.1    Neumann, D.L.2    Waters, A.M.3
  • 12
    • 84929908682 scopus 로고    scopus 로고
    • Neuronal circuits for fear and anxiety
    • Tovote P, Fadok JP, Luthi A. Neuronal circuits for fear and anxiety. Nat Rev Neurosci 2015; 16: 317-331.
    • (2015) Nat Rev Neurosci , vol.16 , pp. 317-331
    • Tovote, P.1    Fadok, J.P.2    Luthi, A.3
  • 13
    • 84907879931 scopus 로고    scopus 로고
    • Mechanisms to medicines: Elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders
    • Bukalo O, Pinard CR, Holmes A. Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders. Br J Pharmacol 2014; 171: 4690-4718.
    • (2014) Br J Pharmacol , vol.171 , pp. 4690-4718
    • Bukalo, O.1    Pinard, C.R.2    Holmes, A.3
  • 14
    • 84896976354 scopus 로고    scopus 로고
    • HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: Where do we stand?
    • Whittle N, Singewald N. HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: where do we stand? Biochem Soc Trans 2014; 42: 569-581.
    • (2014) Biochem Soc Trans , vol.42 , pp. 569-581
    • Whittle, N.1    Singewald, N.2
  • 15
    • 84926126376 scopus 로고    scopus 로고
    • Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders
    • Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ. Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther 2015; 149: 150-190.
    • (2015) Pharmacol Ther , vol.149 , pp. 150-190
    • Singewald, N.1    Schmuckermair, C.2    Whittle, N.3    Holmes, A.4    Ressler, K.J.5
  • 16
    • 84859739523 scopus 로고    scopus 로고
    • Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes
    • Camp M, MacPherson KP, Lederle L, Graybeal C, Gaburro S, Debrouse LM et al. Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes. Neuropsycho-pharmacology 2012; 37: 1534-1547.
    • (2012) Neuropsycho-pharmacology , vol.37 , pp. 1534-1547
    • Camp, M.1    Kp, M.2    Lederle, L.3    Graybeal, C.4    Gaburro, S.5    Debrouse, L.M.6
  • 17
    • 70449396805 scopus 로고    scopus 로고
    • Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain
    • Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, Yilmazer-Hanke D et al. Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain. Genes Brain Behav 2009; 8: 744-752.
    • (2009) Genes Brain Behav , vol.8 , pp. 744-752
    • Camp, M.1    Norcross, M.2    Whittle, N.3    Feyder, M.4    D'Hanis, W.5    Yilmazer-Hanke, D.6
  • 19
    • 84879412059 scopus 로고    scopus 로고
    • Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
    • Gunduz-Cinar O, Macpherson KP, Cinar R, Gamble-George J, Sugden K, Williams B et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. Mol Psychiatry 2013; 7: 813-823.
    • (2013) Mol Psychiatry , vol.7 , pp. 813-823
    • Gunduz-Cinar, O.1    Kp, M.2    Cinar, R.3    Gamble-George, J.4    Sugden, K.5    Williams, B.6
  • 20
    • 51149117197 scopus 로고    scopus 로고
    • Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain
    • Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson RM, Saksida LM et al. Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain. J Neurosci 2008; 28: 8074-8085.
    • (2008) J Neurosci , vol.28 , pp. 8074-8085
    • Hefner, K.1    Whittle, N.2    Juhasz, J.3    Norcross, M.4    Karlsson, R.M.5    Saksida, L.M.6
  • 22
    • 77958025163 scopus 로고    scopus 로고
    • Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction
    • Whittle N, Hauschild M, Lubec G, Holmes A, Singewald N. Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction. J Neurosci 2010; 30: 13586-13596.
    • (2010) J Neurosci , vol.30 , pp. 13586-13596
    • Whittle, N.1    Hauschild, M.2    Lubec, G.3    Holmes, A.4    Singewald, N.5
  • 23
    • 84866368797 scopus 로고    scopus 로고
    • Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model
    • Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A et al. Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model. Neuro-pharmacology 2013; 64: 414-423.
    • (2013) Neuro-pharmacology , vol.64 , pp. 414-423
    • Whittle, N.1    Schmuckermair, C.2    Gunduz Cinar, O.3    Hauschild, M.4    Ferraguti, F.5    Holmes, A.6
  • 24
    • 58249118862 scopus 로고    scopus 로고
    • Transcription factors in long-term memory and synaptic plasticity
    • Alberini CM. Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 2009; 89: 121-145.
    • (2009) Physiol Rev , vol.89 , pp. 121-145
    • Alberini, C.M.1
  • 25
    • 0035798238 scopus 로고    scopus 로고
    • The molecular biology of memory storage: A dialogue between genes and synapses
    • Kandel ER. The molecular biology of memory storage: a dialogue between genes and synapses. Science 2001; 294: 1030-1038.
    • (2001) Science , vol.294 , pp. 1030-1038
    • Kandel, E.R.1
  • 26
    • 0037079060 scopus 로고    scopus 로고
    • Behavioral and neural analysis of extinction
    • Myers KM, Davis M. Behavioral and neural analysis of extinction. Neuron 2002; 36: 567-584.
    • (2002) Neuron , vol.36 , pp. 567-584
    • Myers, K.M.1    Davis, M.2
  • 27
    • 84865627820 scopus 로고    scopus 로고
    • Extinction treatment in multiple contexts attenuates ABC renewal in humans
    • Balooch SB, Neumann DL, Boschen MJ. Extinction treatment in multiple contexts attenuates ABC renewal in humans. Behav Res Ther 2012; 50: 604-609.
    • (2012) Behav Res Ther , vol.50 , pp. 604-609
    • Balooch, S.B.1    Neumann, D.L.2    Boschen, M.J.3
  • 28
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GCJ. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993; 123: 1939-1951.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.J.3
  • 29
    • 84979787957 scopus 로고    scopus 로고
    • Combined neuropeptide S and D-cycloserine augmentation prevents the return of fear in extinction-impaired rodents: Advantage of dual versus single drug approaches
    • Sartori SB, Maurer V, Murphy C, Schmuckermair C, Muigg P, Neumann ID et al. Combined neuropeptide S and D-cycloserine augmentation prevents the return of fear in extinction-impaired rodents: advantage of dual versus single drug approaches. Int J Neuropsychopharmacol 2016; 19: pii: pyv128.
    • (2016) Int J Neuropsychopharmacol , vol.19
    • Sartori, S.B.1    Maurer, V.2    Murphy, C.3    Schmuckermair, C.4    Muigg, P.5    Neumann, I.D.6
  • 30
    • 36549089500 scopus 로고    scopus 로고
    • Neural mechanisms of extinction learning and retrieval
    • Quirk GJ, Mueller D. Neural mechanisms of extinction learning and retrieval. Neuropsychopharmacology 2008; 33: 56-72.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 56-72
    • Quirk, G.J.1    Mueller, D.2
  • 31
    • 77951041564 scopus 로고    scopus 로고
    • Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear
    • Pape HC, Pare D. Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear. Physiol Rev 2010; 90: 419-463.
    • (2010) Physiol Rev , vol.90 , pp. 419-463
    • Pape, H.C.1    Pare, D.2
  • 32
    • 4644370989 scopus 로고    scopus 로고
    • Learning-induced activation of transcription factors among multiple memory systems
    • Colombo PJ. Learning-induced activation of transcription factors among multiple memory systems. Neurobiol Learn Mem 2004; 82: 268-277.
    • (2004) Neurobiol Learn Mem , vol.82 , pp. 268-277
    • Colombo, P.J.1
  • 33
    • 8844273373 scopus 로고    scopus 로고
    • A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK?
    • Knapska E, Kaczmarek L. A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK? Prog Neurobiol 2004; 74: 183-211.
    • (2004) Prog Neurobiol , vol.74 , pp. 183-211
    • Knapska, E.1    Kaczmarek, L.2
  • 34
    • 0029161068 scopus 로고
    • Novel dopamine receptors half a decade later
    • Sokoloff P, Schwartz JC. Novel dopamine receptors half a decade later. Trends Pharmacol Sci 1995; 16: 270-275.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 270-275
    • Sokoloff, P.1    Schwartz, J.C.2
  • 35
    • 0041696476 scopus 로고    scopus 로고
    • L-DOPA increases noradrenaline turnover in central and peripheral nervous systems
    • Dayan L, Finberg JP. L-DOPA increases noradrenaline turnover in central and peripheral nervous systems. Neuropharmacology 2003; 45: 524-533.
    • (2003) Neuropharmacology , vol.45 , pp. 524-533
    • Dayan, L.1    Finberg, J.P.2
  • 36
    • 0020539160 scopus 로고
    • A comparison of the effects of reversible and irreversible inhibitors of aromatic L-amino acid decarboxylase on the half-life and other pharmacokinetic parameters of oral L-3, 4-dihydrox-yphenylalanine
    • Huebert ND, Palfreyman MG, Haegele KD. A comparison of the effects of reversible and irreversible inhibitors of aromatic L-amino acid decarboxylase on the half-life and other pharmacokinetic parameters of oral L-3, 4-dihydrox-yphenylalanine. Drug Metab Dispos 1983; 11: 195-200.
    • (1983) Drug Metab Dispos , vol.11 , pp. 195-200
    • Huebert, N.D.1    Palfreyman, M.G.2    Haegele, K.D.3
  • 37
    • 0032750752 scopus 로고    scopus 로고
    • Striatal dopamine metabolism in monoamine oxidase B-deficient mice: A brain dialysis study
    • Fornai F, Chen K, Giorgi FS, Gesi M, Alessandri MG, Shih JC. Striatal dopamine metabolism in monoamine oxidase B-deficient mice: a brain dialysis study. J Neurochem 1999; 73: 2434-2440.
    • (1999) J Neurochem , vol.73 , pp. 2434-2440
    • Fornai, F.1    Chen, K.2    Giorgi, F.S.3    Gesi, M.4    Alessandri, M.G.5    Shih, J.C.6
  • 38
    • 84876010140 scopus 로고    scopus 로고
    • Loss of histone deace-tylase 2 improves working memory and accelerates extinction learning
    • Morris MJ, Mahgoub M, Na ES, Pranav H, Monteggia LM. Loss of histone deace-tylase 2 improves working memory and accelerates extinction learning. J Neurosci 2013; 33: 6401-6411.
    • (2013) J Neurosci , vol.33 , pp. 6401-6411
    • Morris, M.J.1    Mahgoub, M.2    Na, E.S.3    Pranav, H.4    Monteggia, L.M.5
  • 39
    • 84863393776 scopus 로고    scopus 로고
    • Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene
    • Fujita Y, Morinobu S, Takei S, Fuchikami M, Matsumoto T, Yamamoto S et al. Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene. J Psychiatr Res 2012; 46: 635-643.
    • (2012) J Psychiatr Res , vol.46 , pp. 635-643
    • Fujita, Y.1    Morinobu, S.2    Takei, S.3    Fuchikami, M.4    Matsumoto, T.5    Yamamoto, S.6
  • 40
    • 84881609833 scopus 로고    scopus 로고
    • Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder
    • Matsumoto Y, Morinobu S, Yamamoto S, Matsumoto T, Takei S, Fujita Y et al. Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder. Psychopharmacology 2013; 229: 51-62.
    • (2013) Psychopharmacology , vol.229 , pp. 51-62
    • Matsumoto, Y.1    Morinobu, S.2    Yamamoto, S.3    Matsumoto, T.4    Takei, S.5    Fujita, Y.6
  • 41
    • 84903270821 scopus 로고    scopus 로고
    • Active, phos-phorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
    • Hait NC, Wise LE, Allegood JC, O'Brien M, Avni D, Reeves TM et al. Active, phos-phorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci 2014; 17: 971-980.
    • (2014) Nat Neurosci , vol.17 , pp. 971-980
    • Hait, N.C.1    Wise, L.E.2    Allegood, J.C.3    O'Brien, M.4    Avni, D.5    Reeves, T.M.6
  • 42
    • 35748972690 scopus 로고    scopus 로고
    • Systemic or intrahippocampal delivery of his-tone deacetylase inhibitors facilitates fear extinction
    • Lattal KM, Barrett RM, Wood MA. Systemic or intrahippocampal delivery of his-tone deacetylase inhibitors facilitates fear extinction. Behav Neurosci 2007; 121: 1125-1131.
    • (2007) Behav Neurosci , vol.121 , pp. 1125-1131
    • Lattal, K.M.1    Barrett, R.M.2    Wood, M.A.3
  • 43
    • 84861187305 scopus 로고    scopus 로고
    • Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinction
    • Stafford JM, Raybuck JD, Ryabinin AE, Lattal KM. Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinction. Biol Psychiatry 2012; 72: 25-33.
    • (2012) Biol Psychiatry , vol.72 , pp. 25-33
    • Stafford, J.M.1    Raybuck, J.D.2    Ryabinin, A.E.3    Lattal, K.M.4
  • 44
    • 84861187647 scopus 로고    scopus 로고
    • Histone acetylation rescues contextual fear conditioning in nNOS KO mice and accelerates extinction of cued fear conditioning in wild type mice
    • Itzhak Y, Anderson KL, Kelley JB, Petkov M. Histone acetylation rescues contextual fear conditioning in nNOS KO mice and accelerates extinction of cued fear conditioning in wild type mice. Neurobiol Learn Mem 2012; 97: 409-417.
    • (2012) Neurobiol Learn Mem , vol.97 , pp. 409-417
    • Itzhak, Y.1    Anderson, K.L.2    Kelley, J.B.3    Petkov, M.4
  • 45
    • 34247224239 scopus 로고    scopus 로고
    • Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear
    • Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, Barad M. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem 2007; 14: 268-276.
    • (2007) Learn Mem , vol.14 , pp. 268-276
    • Bredy, T.W.1    Wu, H.2    Crego, C.3    Zellhoefer, J.4    Sun, Y.E.5    Barad, M.6
  • 46
    • 38649140454 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear
    • Bredy TW, Barad M. The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear. Learn Mem 2008; 15: 39-45.
    • (2008) Learn Mem , vol.15 , pp. 39-45
    • Bredy, T.W.1    Barad, M.2
  • 47
    • 84892776254 scopus 로고    scopus 로고
    • Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories
    • Graff J, Joseph NF, Horn ME, Samiei A, Meng J, Seo J et al. Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories. Cell 2014; 156: 261-276.
    • (2014) Cell , vol.156 , pp. 261-276
    • Graff, J.1    Joseph, N.F.2    Horn, M.E.3    Samiei, A.4    Meng, J.5    Seo, J.6
  • 48
    • 80052460370 scopus 로고    scopus 로고
    • Zinc deprivation mediates alcohol-induced hepatocyte IL-8 analog expression in rodents via an epigenetic mechanism
    • Zhao Y, Zhong W, Sun X, Song Z, Clemens DL, Kang YJ et al. Zinc deprivation mediates alcohol-induced hepatocyte IL-8 analog expression in rodents via an epigenetic mechanism. Am J Pathol 2011; 179: 693-702.
    • (2011) Am J Pathol , vol.179 , pp. 693-702
    • Zhao, Y.1    Zhong, W.2    Sun, X.3    Song, Z.4    Clemens, D.L.5    Kang, Y.J.6
  • 49
    • 79952396960 scopus 로고    scopus 로고
    • Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
    • Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P, Michon AM et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol 2011; 29: 255-265.
    • (2011) Nat Biotechnol , vol.29 , pp. 255-265
    • Bantscheff, M.1    Hopf, C.2    Savitski, M.M.3    Dittmann, A.4    Grandi, P.5    Michon, A.M.6
  • 50
    • 33846648800 scopus 로고    scopus 로고
    • Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears
    • Corcoran KA, Quirk GJ. Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears. J Neurosci 2007; 27: 840-844.
    • (2007) J Neurosci , vol.27 , pp. 840-844
    • Corcoran, K.A.1    Quirk, G.J.2
  • 51
    • 66149109346 scopus 로고    scopus 로고
    • Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure
    • Burgos-Robles A, Vidal-Gonzalez I, Quirk GJ. Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure. J Neurosci 2009; 29: 8474-8482.
    • (2009) J Neurosci , vol.29 , pp. 8474-8482
    • Burgos-Robles, A.1    Vidal-Gonzalez, I.2    Quirk, G.J.3
  • 52
    • 78650169462 scopus 로고    scopus 로고
    • Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear
    • Sierra-Mercado D, Padilla-Coreano N, Quirk GJ. Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology 2011; 36: 529-538.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 529-538
    • Sierra-Mercado, D.1    Padilla-Coreano, N.2    Quirk, G.J.3
  • 53
    • 33748471314 scopus 로고    scopus 로고
    • Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear
    • Vidal-Gonzalez I, Vidal-Gonzalez B, Rauch SL, Quirk GJ. Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn Mem 2006; 13: 728-733.
    • (2006) Learn Mem , vol.13 , pp. 728-733
    • Vidal-Gonzalez, I.1    Vidal-Gonzalez, B.2    Rauch, S.L.3    Quirk, G.J.4
  • 54
    • 0034663007 scopus 로고    scopus 로고
    • The role of ventromedial prefrontal cortex in the recovery of extinguished fear
    • Quirk GJ, Russo GK, Barron JL, Lebron K. The role of ventromedial prefrontal cortex in the recovery of extinguished fear. J Neurosci 2000; 20: 6225-6231.
    • (2000) J Neurosci , vol.20 , pp. 6225-6231
    • Quirk, G.J.1    Russo, G.K.2    Barron, J.L.3    Lebron, K.4
  • 55
    • 0141869827 scopus 로고    scopus 로고
    • Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons
    • Quirk GJ, Likhtik E, Pelletier JG, Pare D. Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons. J Neurosci 2003; 23: 8800-8807.
    • (2003) J Neurosci , vol.23 , pp. 8800-8807
    • Quirk, G.J.1    Likhtik, E.2    Pelletier, J.G.3    Pare, D.4
  • 56
    • 0037080322 scopus 로고    scopus 로고
    • Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice
    • Herry C, Garcia R. Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice. J Neurosci 2002; 22: 577-583.
    • (2002) J Neurosci , vol.22 , pp. 577-583
    • Herry, C.1    Garcia, R.2
  • 57
    • 3843072212 scopus 로고    scopus 로고
    • Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala
    • Herry C, Mons N. Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala. Eur J Neurosci 2004; 20: 781-790.
    • (2004) Eur J Neurosci , vol.20 , pp. 781-790
    • Herry, C.1    Mons, N.2
  • 58
    • 0037038369 scopus 로고    scopus 로고
    • Neurons in medial prefrontal cortex signal memory for fear extinction
    • Milad MR, Quirk GJ. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 2002; 420: 70-74.
    • (2002) Nature , vol.420 , pp. 70-74
    • Milad, M.R.1    Quirk, G.J.2
  • 59
    • 0038045436 scopus 로고    scopus 로고
    • Metabolic mapping of mouse brain activity after extinction of a conditioned emotional response
    • Barrett D, Shumake J, Jones D, Gonzalez-Lima F. Metabolic mapping of mouse brain activity after extinction of a conditioned emotional response. J Neurosci 2003; 23: 5740-5749.
    • (2003) J Neurosci , vol.23 , pp. 5740-5749
    • Barrett, D.1    Shumake, J.2    Jones, D.3    Gonzalez-Lima, F.4
  • 60
    • 68149092650 scopus 로고    scopus 로고
    • Reciprocal patterns of c-Fos expression in the medial pre-frontal cortex and amygdala after extinction and renewal of conditioned fear
    • Knapska E, Maren S. Reciprocal patterns of c-Fos expression in the medial pre-frontal cortex and amygdala after extinction and renewal of conditioned fear. Learn Mem 2009; 16: 486-493.
    • (2009) Learn Mem , vol.16 , pp. 486-493
    • Knapska, E.1    Maren, S.2
  • 62
    • 4544292021 scopus 로고    scopus 로고
    • Extinction learning in humans: Role of the amygdala and vmPFC
    • Phelps EA, Delgado MR, Nearing KI, LeDoux JE. Extinction learning in humans: role of the amygdala and vmPFC. Neuron 2004; 43: 897-905.
    • (2004) Neuron , vol.43 , pp. 897-905
    • Phelps, E.A.1    Delgado, M.R.2    Nearing, K.I.3    LeDoux, J.E.4
  • 63
    • 34250783547 scopus 로고    scopus 로고
    • Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert
    • Milad MR, Wright CI, Orr SP, Pitman RK, Quirk GJ, Rauch SL. Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol Psychiatry 2007; 62: 446-454.
    • (2007) Biol Psychiatry , vol.62 , pp. 446-454
    • Milad, M.R.1    Wright, C.I.2    Orr, S.P.3    Pitman, R.K.4    Quirk, G.J.5    Rauch, S.L.6
  • 64
    • 70350525706 scopus 로고    scopus 로고
    • Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder
    • Milad MR, Pitman RK, Ellis CB, Gold AL, Shin LM, Lasko NB et al. Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol Psychiatry 2009; 66: 1075-1082.
    • (2009) Biol Psychiatry , vol.66 , pp. 1075-1082
    • Milad, M.R.1    Pitman, R.K.2    Ellis, C.B.3    Gold, A.L.4    Shin, L.M.5    Lasko, N.B.6
  • 65
    • 42149169718 scopus 로고    scopus 로고
    • Differential roles for hippocampal areas CA1 and CA3 in the contextual encoding and retrieval of extinguished fear
    • Ji J, Maren S. Differential roles for hippocampal areas CA1 and CA3 in the contextual encoding and retrieval of extinguished fear. Learn Mem 2008; 15: 244-251.
    • (2008) Learn Mem , vol.15 , pp. 244-251
    • Ji, J.1    Maren, S.2
  • 66
    • 84930667466 scopus 로고    scopus 로고
    • Fear renewal preferentially activates ventral hippocampal neurons projecting to both amygdala and prefrontal cortex in rats
    • Jin J, Maren S. Fear renewal preferentially activates ventral hippocampal neurons projecting to both amygdala and prefrontal cortex in rats. Sci Rep 2015; 5: 8388.
    • (2015) Sci Rep , vol.5 , pp. 8388
    • Jin, J.1    Maren, S.2
  • 67
    • 34648846408 scopus 로고    scopus 로고
    • Time course of extracellular catecholamine and glu-tamate levels in the rat medial prefrontal cortex during and after extinction of conditioned fear
    • Hugues S, Garcia R, Lena I. Time course of extracellular catecholamine and glu-tamate levels in the rat medial prefrontal cortex during and after extinction of conditioned fear. Synapse 2007; 61: 933-937.
    • (2007) Synapse , vol.61 , pp. 933-937
    • Hugues, S.1    Garcia, R.2    Lena, I.3
  • 68
    • 44649115764 scopus 로고    scopus 로고
    • Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear con-ditioning
    • Hikind N, Maroun M. Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear con-ditioning. Neurobiol Learn Mem 2008; 90: 217-222.
    • (2008) Neurobiol Learn Mem , vol.90 , pp. 217-222
    • Hikind, N.1    Maroun, M.2
  • 69
    • 78349309096 scopus 로고    scopus 로고
    • Infralimbic D2 receptors are necessary for fear extinction and extinction-related tone responses
    • Mueller D, Bravo-Rivera C, Quirk GJ. Infralimbic D2 receptors are necessary for fear extinction and extinction-related tone responses. Biol Psychiatry 2010; 68: 1055-1060.
    • (2010) Biol Psychiatry , vol.68 , pp. 1055-1060
    • Mueller, D.1    Bravo-Rivera, C.2    Quirk, G.J.3
  • 70
    • 84957818334 scopus 로고    scopus 로고
    • Activation of D1/5 dopamine receptors: A common mechanism for enhancing extinction of fear and reward-seeking behaviors
    • Abraham AD, Neve KA, Lattal KM. Activation of D1/5 dopamine receptors: a common mechanism for enhancing extinction of fear and reward-seeking behaviors. Neuropsychopharmacology 2016; 41: 2072-2081.
    • (2016) Neuropsychopharmacology , vol.41 , pp. 2072-2081
    • Abraham, A.D.1    Neve, K.A.2    Lattal, K.M.3
  • 71
    • 23744506020 scopus 로고    scopus 로고
    • Systemic blockade of D2-like dopamine receptors facilitates extinction of conditioned fear in mice
    • Ponnusamy R, Nissim HA, Barad M. Systemic blockade of D2-like dopamine receptors facilitates extinction of conditioned fear in mice. Learn Mem 2005; 12: 399-406.
    • (2005) Learn Mem , vol.12 , pp. 399-406
    • Ponnusamy, R.1    Nissim, H.A.2    Barad, M.3
  • 72
    • 84879530897 scopus 로고    scopus 로고
    • Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear
    • Haaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K et al. Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear. Proc Natl Acad Sci USA 2013; 110: E2428-E2436.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E2428-E2436
    • Haaker, J.1    Gaburro, S.2    Sah, A.3    Gartmann, N.4    Lonsdorf, T.B.5    Meier, K.6
  • 73
    • 84872224226 scopus 로고    scopus 로고
    • The potential of HDAC inhibitors as cognitive enhancers
    • Graff J, Tsai LH. The potential of HDAC inhibitors as cognitive enhancers. Annu Rev Pharmacol Toxicol 2013; 53: 311-330.
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 311-330
    • Graff, J.1    Tsai, L.H.2
  • 74
    • 84872601036 scopus 로고    scopus 로고
    • Histone acetylation: Molecular mnemonics on the chromatin
    • Graff J, Tsai LH. Histone acetylation: molecular mnemonics on the chromatin. Nat Rev Neurosci 2013; 14: 97-111.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 97-111
    • Graff, J.1    Tsai, L.H.2
  • 75
    • 84929583345 scopus 로고    scopus 로고
    • Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala
    • Ferreira AN, Yousuf H, Dalton S, Sheets PL. Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala. Front Cell Neurosci 2015; 9: 161.
    • (2015) Front Cell Neurosci , vol.9 , pp. 161
    • Ferreira, A.N.1    Yousuf, H.2    Dalton, S.3    Sheets, P.L.4
  • 77
    • 84890554863 scopus 로고    scopus 로고
    • Synaptic encoding of fear extinction in mPFC-amygdala circuits
    • Cho JH, Deisseroth K, Bolshakov VY. Synaptic encoding of fear extinction in mPFC-amygdala circuits. Neuron 2013; 80: 1491-1507.
    • (2013) Neuron , vol.80 , pp. 1491-1507
    • Cho, J.H.1    Deisseroth, K.2    Bolshakov, V.Y.3
  • 78
    • 84860602165 scopus 로고    scopus 로고
    • Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex
    • Maroun M, Kavushansky A, Holmes A, Wellman C, Motanis H. Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex. PLoS One 2012; 7: e35853.
    • (2012) PLoS One , vol.7 , pp. e35853
    • Maroun, M.1    Kavushansky, A.2    Holmes, A.3    Wellman, C.4    Motanis, H.5
  • 79
    • 84930276850 scopus 로고    scopus 로고
    • PTSD-like memory generated through enhanced noradrenergic activity is mitigated by a dual step pharmacological intervention targeting its reconsolidation
    • Gazarini L, Stern CA, Piornedo RR, Takahashi RN, Bertoglio LJ. PTSD-like memory generated through enhanced noradrenergic activity is mitigated by a dual step pharmacological intervention targeting its reconsolidation. Int J Neuropsycho-pharmacol 2014, 18: pii: pyu026.
    • (2014) Int J Neuropsycho-pharmacol , vol.18
    • Gazarini, L.1    Stern, C.A.2    Piornedo, R.R.3    Takahashi, R.N.4    Bertoglio, L.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.