Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene

Journal of Psychiatric Research

Volumn 46, Issue 5, 2012, Pages 635-643

  Fujita, Yosuke ^a   Morinobu, Shigeru ^a   Takei, Shiro ^a   Fuchikami, Manabu ^a   Matsumoto, Tomoya ^a   Yamamoto, Shigeto ^a   Yamawaki, Shigeto ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Extinction; HDAC inhibitor; Hippocampus; NR2B; Vorinostat

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HISTONE H3; HISTONE H4; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; VORINOSTAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONDITIONING; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DRUG EFFECT; FEAR; HIPPOCAMPUS; HISTONE ACETYLATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 84863393776     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2012.01.026     Document Type: Article

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