-
1
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed crohn’s disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed crohn’s disease susceptibility loci. Nature genetics 42: 1118–1125. doi: 10.1038/ng.717 21102463
-
(2010)
Nature genetics
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
-
2
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell SM, Wray NR, Stone JL, Visscher PM, O’Donovan MC, et al. (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460: 748–752. doi: 10.1038/nature08185 19571811
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O’Donovan, M.C.5
-
3
-
-
77954140531
-
Common snps explain a large proportion of the heritability for human height
-
Yang J, Benyamin B, McEvoy BP, Gordon S, Henders AK, et al. (2010) Common snps explain a large proportion of the heritability for human height. Nature genetics 42: 565–569. doi: 10.1038/ng.608 20562875
-
(2010)
Nature genetics
, vol.42
, pp. 565-569
-
-
Yang, J.1
Benyamin, B.2
McEvoy, B.P.3
Gordon, S.4
Henders, A.K.5
-
4
-
-
80053132878
-
Genome-wide association studies establish that human intelligence is highly heritable and polygenic
-
Davies G, Tenesa A, Payton A, Yang J, Harris SE, et al. (2011) Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Molecular psychiatry 16: 996–1005. doi: 10.1038/mp.2011.85 21826061
-
(2011)
Molecular psychiatry
, vol.16
, pp. 996-1005
-
-
Davies, G.1
Tenesa, A.2
Payton, A.3
Yang, J.4
Harris, S.E.5
-
5
-
-
84944358132
-
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
-
Yang J, Bakshi A, Zhu Z, Hemani G, Vinkhuyzen AA, et al. (2015) Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nature genetics. doi: 10.1038/ng.3390
-
(2015)
Nature genetics
-
-
Yang, J.1
Bakshi, A.2
Zhu, Z.3
Hemani, G.4
Vinkhuyzen, A.A.5
-
6
-
-
0037146578
-
Finding genes that underlie complex traits
-
Glazier AM, Nadeau JH, Aitman TJ, (2002) Finding genes that underlie complex traits. Science 298: 2345–2349. doi: 10.1126/science.1076641 12493905
-
(2002)
Science
, vol.298
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
7
-
-
0035045051
-
Prediction of total genetic value using genome-wide dense marker maps
-
Hayes B, Goddard M, et al. (2001) Prediction of total genetic value using genome-wide dense marker maps. Genetics 157: 1819–1829. 11290733
-
(2001)
Genetics
, vol.157
, pp. 1819-1829
-
-
Hayes, B.1
Goddard, M.2
-
8
-
-
34948877698
-
Prediction of individual genetic risk to disease from genome-wide association studies
-
Wray NR, Goddard ME, Visscher PM, (2007) Prediction of individual genetic risk to disease from genome-wide association studies. Genome research 17: 1520–1528. doi: 10.1101/gr.6665407 17785532
-
(2007)
Genome research
, vol.17
, pp. 1520-1528
-
-
Wray, N.R.1
Goddard, M.E.2
Visscher, P.M.3
-
9
-
-
84870919039
-
Improved heritability estimation from genome-wide snps
-
Speed D, Hemani G, Johnson MR, Balding DJ, (2012) Improved heritability estimation from genome-wide snps. The American Journal of Human Genetics 91: 1011–1021. doi: 10.1016/j.ajhg.2012.10.010 23217325
-
(2012)
The American Journal of Human Genetics
, vol.91
, pp. 1011-1021
-
-
Speed, D.1
Hemani, G.2
Johnson, M.R.3
Balding, D.J.4
-
10
-
-
84874783818
-
Polygenic modeling with bayesian sparse linear mixed models
-
Zhou X, Carbonetto P, Stephens M, (2013) Polygenic modeling with bayesian sparse linear mixed models. PLoS genetics 9: e1003264. doi: 10.1371/journal.pgen.1003264 23408905
-
(2013)
PLoS genetics
, vol.9
, pp. e1003264
-
-
Zhou, X.1
Carbonetto, P.2
Stephens, M.3
-
11
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, et al. (2010) Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nature genetics 42: 570–575. doi: 10.1038/ng.610 20562874
-
(2010)
Nature genetics
, vol.42
, pp. 570-575
-
-
Park, J.H.1
Wacholder, S.2
Gail, M.H.3
Peters, U.4
Jacobs, K.B.5
-
12
-
-
81055145433
-
Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
-
Park JH, Gail MH, Weinberg CR, Carroll RJ, Chung CC, et al. (2011) Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants. Proceedings of the National Academy of Sciences 108: 18026–18031. doi: 10.1073/pnas.1114759108
-
(2011)
Proceedings of the National Academy of Sciences
, vol.108
, pp. 18026-18031
-
-
Park, J.H.1
Gail, M.H.2
Weinberg, C.R.3
Carroll, R.J.4
Chung, C.C.5
-
13
-
-
84953245254
-
Ld score regression distinguishes confounding from polygenicity in genome-wide association studies
-
Bulik-Sullivan B, Loh PR, Finucane H, Ripke S, Yang J, et al. (2014) Ld score regression distinguishes confounding from polygenicity in genome-wide association studies. bioRxiv: 002931.
-
(2014)
bioRxiv
-
-
Bulik-Sullivan, B.1
Loh, P.R.2
Finucane, H.3
Ripke, S.4
Yang, J.5
-
14
-
-
67649859496
-
Estimating the posterior probability that genome-wide association findings are true or false
-
Bukszár J, McClay JL, van den Oord EJ, (2009) Estimating the posterior probability that genome-wide association findings are true or false. Bioinformatics 25: 1807–1813. doi: 10.1093/bioinformatics/btp305 19420056
-
(2009)
Bioinformatics
, vol.25
, pp. 1807-1813
-
-
Bukszár, J.1
McClay, J.L.2
van den Oord, E.J.3
-
15
-
-
79959241413
-
Genomic inflation factors under polygenic inheritance
-
Yang J, Weedon MN, Purcell S, Lettre G, Estrada K, et al. (2011) Genomic inflation factors under polygenic inheritance. European Journal of Human Genetics 19: 807–812. doi: 10.1038/ejhg.2011.39 21407268
-
(2011)
European Journal of Human Genetics
, vol.19
, pp. 807-812
-
-
Yang, J.1
Weedon, M.N.2
Purcell, S.3
Lettre, G.4
Estrada, K.5
-
16
-
-
84875700256
-
Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
-
Chatterjee N, Wheeler B, Sampson J, Hartge P, Chanock SJ, et al. (2013) Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies. Nature genetics 45: 400–405. doi: 10.1038/ng.2579 23455638
-
(2013)
Nature genetics
, vol.45
, pp. 400-405
-
-
Chatterjee, N.1
Wheeler, B.2
Sampson, J.3
Hartge, P.4
Chanock, S.J.5
-
17
-
-
84876847154
-
All snps are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated snps
-
Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, et al. (2013) All snps are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated snps. PLoS Genet 9: e1003449. doi: 10.1371/journal.pgen.1003449 23637621
-
(2013)
PLoS Genet
, vol.9
, pp. e1003449
-
-
Schork, A.J.1
Thompson, W.K.2
Pham, P.3
Torkamani, A.4
Roddey, J.C.5
-
18
-
-
84904959814
-
-
Zablocki RW, Schork AJ, Levine RA, Andreassen OA, Dale AM, et al. (2014) Covariate-modulated local false discovery rate for genome-wide association studies. Bioinformatics: btu145.
-
(2014)
Bioinformatics
-
-
Zablocki, R.W.1
Schork, A.J.2
Levine, R.A.3
Andreassen, O.A.4
Dale, A.M.5
-
19
-
-
0035992248
-
Empirical bayes methods and false discovery rates for microarrays
-
Efron B, Tibshirani R, (2002) Empirical bayes methods and false discovery rates for microarrays. Genetic epidemiology 23: 70–86. doi: 10.1002/gepi.1124 12112249
-
(2002)
Genetic epidemiology
, vol.23
, pp. 70-86
-
-
Efron, B.1
Tibshirani, R.2
-
20
-
-
80053384370
-
Genome-wide association study identifies five new schizophrenia loci
-
Consortium SPGWASG, et al. (2011) Genome-wide association study identifies five new schizophrenia loci. Nature genetics 43: 969–976. doi: 10.1038/ng.940
-
(2011)
Nature genetics
, vol.43
, pp. 969-976
-
-
Consortium, S.P.G.W.A.S.G.1
-
21
-
-
0034991524
-
Review article: the genetics of inflammatory bowel disease
-
Ahmad T, Satsangi J, McGovern D, Bunce M, DP J, (2002) Review article: the genetics of inflammatory bowel disease. Aliment Pharmacol Ther 15: 731–748. doi: 10.1046/j.1365-2036.2001.00981.x
-
(2002)
Aliment Pharmacol Ther
, vol.15
, pp. 731-748
-
-
Ahmad, T.1
Satsangi, J.2
McGovern, D.3
Bunce, M.4
Dp, J.5
-
22
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee SH, Wray NR, Goddard ME, Visscher PM, (2011) Estimating missing heritability for disease from genome-wide association studies. The American Journal of Human Genetics 88: 294–305. doi: 10.1016/j.ajhg.2011.02.002 21376301
-
(2011)
The American Journal of Human Genetics
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
Visscher, P.M.4
-
24
-
-
0344305525
-
Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
-
Sullivan PF, Kendler KS, Neale MC, (2003) Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Archives of general psychiatry 60: 1187–1192. doi: 10.1001/archpsyc.60.12.1187 14662550
-
(2003)
Archives of general psychiatry
, vol.60
, pp. 1187-1192
-
-
Sullivan, P.F.1
Kendler, K.S.2
Neale, M.C.3
-
25
-
-
84862777863
-
Estimating the proportion of variation in susceptibility to schizophrenia captured by common snps
-
Lee SH, DeCandia TR, Ripke S, Yang J, Sullivan PF, et al. (2012) Estimating the proportion of variation in susceptibility to schizophrenia captured by common snps. Nature genetics 44: 247–250. doi: 10.1038/ng.1108 22344220
-
(2012)
Nature genetics
, vol.44
, pp. 247-250
-
-
Lee, S.H.1
DeCandia, T.R.2
Ripke, S.3
Yang, J.4
Sullivan, P.F.5
-
26
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
of the Psychiatric Genomics Consortium SWGet al. (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature 511: 421–427. doi: 10.1038/nature13595 25056061
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
27
-
-
38949198791
-
Size, power and false discovery rates
-
Efron B, (2007) Size, power and false discovery rates. The Annals of Statistics 35: 1351–1377. doi: 10.1214/009053606000001460
-
(2007)
The Annals of Statistics
, vol.35
, pp. 1351-1377
-
-
Efron, B.1
-
28
-
-
0032714352
-
Genomic control for association studies
-
Devlin B, Roeder K, (1999) Genomic control for association studies. Biometrics 55: 997–1004. doi: 10.1111/j.0006-341X.1999.00997.x 11315092
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
29
-
-
0022992740
-
Meta-analysis in clinical trials
-
DerSimonian R, Laird N, (1986) Meta-analysis in clinical trials. Controlled clinical trials 7: 177–188. doi: 10.1016/0197-2456(86)90046-2 3802833
-
(1986)
Controlled clinical trials
, vol.7
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
30
-
-
77955133892
-
Estimating effects and making predictions from genome-wide marker data
-
Goddard ME, Wray NR, Verbyla K, Visscher PM, (2009) Estimating effects and making predictions from genome-wide marker data. Statistical Science 24: 517–529. doi: 10.1214/09-STS306
-
(2009)
Statistical Science
, vol.24
, pp. 517-529
-
-
Goddard, M.E.1
Wray, N.R.2
Verbyla, K.3
Visscher, P.M.4
-
31
-
-
84863003734
-
Genome-wide efficient mixed-model analysis for association studies
-
Zhou X, Stephens M, (2012) Genome-wide efficient mixed-model analysis for association studies. Nature genetics 44: 821–824. doi: 10.1038/ng.2310 22706312
-
(2012)
Nature genetics
, vol.44
, pp. 821-824
-
-
Zhou, X.1
Stephens, M.2
-
32
-
-
77955894071
-
Metal: fast and efficient meta-analysis of genomewide association scans
-
Willer CJ, Li Y, Abecasis GR, (2010) Metal: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26: 2190–2191. doi: 10.1093/bioinformatics/btq340 20616382
-
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
-
-
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
-
34
-
-
17644422198
-
Reduction of selection bias in genomewide studies by resampling
-
Sun L, Bull SB, (2005) Reduction of selection bias in genomewide studies by resampling. Genetic epidemiology 28: 352–367. doi: 10.1002/gepi.20068 15761913
-
(2005)
Genetic epidemiology
, vol.28
, pp. 352-367
-
-
Sun, L.1
Bull, S.B.2
-
35
-
-
79958773472
-
A flexible genome-wide bootstrap method that accounts for rankingand threshold-selection bias in gwas interpretation and replication study design
-
Faye LL, Sun L, Dimitromanolakis A, Bull SB, (2011) A flexible genome-wide bootstrap method that accounts for rankingand threshold-selection bias in gwas interpretation and replication study design. Statistics in medicine 30: 1898–1912. doi: 10.1002/sim.4228 21538984
-
(2011)
Statistics in medicine
, vol.30
, pp. 1898-1912
-
-
Faye, L.L.1
Sun, L.2
Dimitromanolakis, A.3
Bull, S.B.4
|