Structural Mechanism for Cargo Recognition by the Retromer Complex

Cell

Volumn 167, Issue 6, 2016, Pages 1623-1635.e14

  Lucas, María ^a   Gershlick, David C ^b   Vidaurrazaga, Ander ^a   Rojas, Adriana L ^a   Bonifacino, Juan S ^b   Hierro, Aitor ^a,c  

^a CIC BIOGUNE   (Spain)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

cargo recognition; endocytic recycling; endosomes; membrane recruitment; membrane tubules; protein coats; retrograde transport; retromer; sorting nexins; sorting signals

Indexed keywords

MULTIPROTEIN COMPLEX; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; RETROMER VPS26 SUBUNIT; RETROMER VPS35 SUBUNIT; SORTING NEXIN; SORTING NEXIN SNX3; UNCLASSIFIED DRUG; CATION TRANSPORT PROTEIN; ISOPROTEIN; SNX3 PROTEIN, HUMAN; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; VESICULAR TRANSPORT PROTEIN; VPS26A PROTEIN, HUMAN; VPS35 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; CRYSTAL STRUCTURE; FEMALE; GENE DELETION; HELA CELL LINE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; SMALL ANGLE SCATTERING;

AMINO ACID SEQUENCE; CATION TRANSPORT PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PROTEIN ISOFORMS; SCATTERING, SMALL ANGLE; SORTING NEXINS; VESICULAR TRANSPORT PROTEINS;

EID: 85002235375     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.10.056     Document Type: Article

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