Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells

Journal of Cell Science

Volumn 128, Issue 3, 2015, Pages 553-565

  Ghai, Rajesh ^a,c   Tello Lafoz, Maria ^b   Norwood, Suzanne J ^b   Yang, Zhe ^b   Clairfeuille, Thomas ^b   Teasdale, Rohan D ^b   Mérida, Isabel ^b   Collins, Brett M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Endosome; FERM domain; Immunological synapse; Phosphoinositide; Phox homology domain; Sorting nexin

Indexed keywords

ACTIN; EZRIN; INTEGRIN; MOESIN; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE B; RADIXIN; SORTING NEXIN; SORTING NEXIN 17; SORTING NEXIN 27; SORTING NEXIN 31; UNCLASSIFIED DRUG; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; POLYPHOSPHOINOSITIDE; PROTEIN BINDING; SNX27 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL ADHESION; CELL CONTACT; CELL MEMBRANE; CELL ORGANELLE; CELL SURFACE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; ENDOCYTOSIS; ENDOSOME; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; IMMUNOLOGICAL SYNAPSE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PDZ DOMAIN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; IMMUNOLOGY; JURKAT CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE, TUMOR; CELL MEMBRANE; ENDOSOMES; HELA CELLS; HUMANS; IMMUNOLOGICAL SYNAPSES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICE; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SORTING NEXINS; T-LYMPHOCYTES;

EID: 84965159696     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.158204     Document Type: Article

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