A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast

Journal of Cell Biology

Volumn 142, Issue 3, 1998, Pages 665-681

  Seaman, Matthew N J ^a,b   McCaffery, J Michael ^a   Emr, Scott D ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Coat; Endosome; Golgi; Retrieval; Vesicle

Indexed keywords

CELL PROTEIN; CYTOPLASM PROTEIN; FUNGAL PROTEIN; MEMBRANE PROTEIN; PROTEIN; PROTEIN VPS17P; PROTEIN VPS26P; PROTEIN VPS29P; PROTEIN VPS35P; PROTEIN VPS5P; UNCLASSIFIED DRUG;

ARTICLE; CELL COMPARTMENTALIZATION; CELL ULTRASTRUCTURE; CELLULAR DISTRIBUTION; COATED VESICLE; COMPLEX FORMATION; ENDOSOME; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; MEMBRANE BINDING; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE;

CARRIER PROTEINS; CENTRIFUGATION, DENSITY GRADIENT; ENDOSOMES; FUNGAL PROTEINS; GOLGI APPARATUS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; VESICULAR TRANSPORT PROTEINS;

EUKARYOTA; FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE;

EID: 0031823307     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.3.665     Document Type: Article

References (64)

1. Babst, M., T.K. Sato, L.M. Banta, and S.D. Emr. 1997. Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO (Eur. Mol. Biol. Organ.) J. 16:1820-1831.
2. Bachhawat, A.K.. J. Suhan, and E.W. Jones. 1994. The yeast homologue of Hβ58, a mouse gene essential for embryogenesis performs a role in the delivery of proteins to the vacuole. Genes Dev. 8:1379-1387.
3. Bankaitis, V.A., L.M. Johnson, and S.D. Emr. 1986. Isolation of yeast mutants defective in protein targeting to the vacuole. Proc. Natl. Acad. Sci. USA. 83: 9075-9079.
4. Banta, L.M., J.S. Robinson, D.J. Klionsky, and S.D. Emr. 1988. Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J. Cell Biol. 107:1369-1383.
5. Becherer, K.A., S.E. Rieder, S.D. Emr, and E.W. Jones. 1996. Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the Iysosome-like vacuole in yeast. Mol. Biol. Cell. 7:579-594.
6. Cereghino, J.L., E.G. Marcusson, and S.D. Emr. 1995. The cytoplasmic tail domain of the vacuolar sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. Mol Biol. Cell. 6:1089-1102.
7. Cooper, A.A., and T.H. Stevens. 1996. Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol. 133:529-542.
8. Damke, H. 1996. Dynamin and receptor-mediated endocytosis. FEBS Lett. 389: 48-51.
9. Ekena, K., and T.H. Stevens. 1995. The Saccharomyces cerevisiae MVP1 geneinteracts with VPS1 and is required for vacuolar protein sorting. Mol. Cell. Biol. 15:1671-1678.
10. Elble, R. 1992. A simple and efficient procedure for transformation of yeasts. Biotechniques. 13:18-20.
11. Glickman, J.N., E. Conibear, and B.M.F. Pearse. 1989. Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor. EMBO (Eur. Mol. Biol. Organ.) J. 8:1041-1047.
12. Hanahan, D. 1983. Studies on transformation of Escherchia coli with plasmids. J. Mol. Biol. 166:557-580.
13. Harlow, E., and D. Lane. 1988. Antibodies. A Laboratory Manual. Cold Spring Harbor Laboralory Press, Plainview, New York. pp. 55-137.
14. Hille-Rehfeld, A. 1995. Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymes. Biochim. Biophys. Acta. 1241:177-194.
15. Horazdovsky, B.F., B.A. Davies, M.N.J. Seaman, S.A. McLaughlin, S.-H. Yoon, and S.D. Emr. 1997. A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. Mol. Biol. Cell. 8:1529-1541.
16. Hwang, S., L.E. Benjamin, B. Oh, J.L. Rothstein, S.L. Ackerman, R.S.P. Beddington, and B.B. Knowles. 1996. Genetic mapping and embryonic expression of a novel, maternally transcribed gene, Mem3. Mamm. Genome. 7: 586-590.
17. Jones, E.W. 1977. Proteinase mutants of Saccharomyces cerevisiae. Genetics. 85: 23-33.
18. Kirchhausen, T., J.S. Bonifacino. and H. Riezman. 1997. Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Cur. Opin. Cell Biol. 9:488-495.
19. Kohrer, K., and S.D. Emr. 1993. The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. J. Biol. Chem. 268:559-569.
20. Kornfeld, S. 1992. Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors. Annu. Rev. Biochem. 61:307-330.
21. Kornfeld, S., and I. Mellman. 1989. The biogenesis of lysosomes. Annu. Rev. Cell Biol. 5:483-525.
22. Kurten, R.C., D.L. Cadena, and G.N. Gill. 1996. Enhanced degradation of EGF receptors by a sorting nexin, SNX1. Science. 272:1008-1010.
23. Le Borgne, R., and B. Hoflack. 1997. Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGN. J. Cell Biol. 137:335-345.
24. Le Borgne, R., A. Schmidt, F. Mauxion, G. Griffiths, and B. Hoflack. 1993. Binding of AP-1 Golgi adaptors to membranes requires phosphorylated cytoplasmic domains of the mannose-6-phosphate/insulin-like growth factor II receptor. J. Biol. Chem. 268:22552-22556.
25. Lee, JJ., G. Radice, C. Perkins, and F. Costantini. 1992. Identification and characterization of a novel, evolutionary conserved gene disrupted by the murine Hβ58 embryonic lethal transgene insertion. Development. 115:277-288.
26. Marcusson. E.G., B.F. Horazdovsky, J.L. Cereghino, E. Gharakhanian, and S.D. Emr. 1994. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell. 77:579-586.
27. McCaffery, J.M., and M.G. Farqhar. 1995. Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy. Methods Enzymol. 257:259-279.
28. Mitchell, D.A., T.K. Marshall, and R.J. Deschenes. 1993. Vectors for the inducible overexpression of glutatnione S-transferase fusion proteins in yeast. Yeast. 9:715-723.
29. Nothwehr, S.F., N.J. Bryant, and T.H. Stevens. 1996. The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol. Cell. Biol. 16:2700-2707.
30. Nothwehr, S.F., E. Conibear, and T.H. Stevens. 1995. Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J. Cell Biol. 129:35-46.
31. Nothwehr, S.F., and A.H. Hindes. 1997. The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late-Golgi. J. Cell Sci. 110:1063-1072.
32. Ohno, H., J. Stewart, M.C. Fournier, H. Bosshart, I. Rhee, S. Miyatake, T. Saito, A. Gallusser, T. Kirchhausen, and J.S. Bonifacino. 1995. Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science. 269: 1872-1875.
33. Ostermann, J., L. Orci, K. Tani, M. Amherdt, M. Ravazzola, Z. Elazar, and J.E. Rothman. 1993. Stepwise assembly of functionally active transport vesicles. Cell. 75:1015-1025.
34. Paravicini, G., B.F. Horazdovsky, and S.D. Emr. 1992. Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. Mol. Biol. Cell. 3:415-427.
35. Payne, G.S., and R. Schekman. 1989. Clathrin: a role in the intracellular retenlion of a Golgi membrane protein. Science. 245:1358-1365.
36. Pearse, B.M.F., and M.S. Robinson. 1990. Clathrin, adaptors, and sorting. Annu. Rev. Cell Biol. 6:151-171.
37. Ponting, C.P. 1996. Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains? Protein Sci. 5:2353-2357.
38. Raymond, C.K., I. Howald-Stevenson, C.A. Vater, and T.H. Stevens. 1992. Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol. Biol. Cell. 3:1389-1402.
39. Redding, K., M. Seeger, G.S. Payne, and R.S. Fuller. 1996. The effects of clathrin inactivation on localization of Kex2 protease are independent of the TGN localization signal in the cytosolic tail of Kex2p. Mol. Biol. Cell. 7:1667-1677.
40. Rieder, S.E., L.M. Banta, K. Kohrer, J.M. McCaffrey, and S.D. Emr. 1996. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol. Biol. Cell. 7:985-999.
41. Riederer, M.A., T. Soldati, A.D. Shapiro, J. Lin, and S.R. Pfeffer. 1994. Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J. Cell Biol. 1994:573-582.
42. Robinson, J.S., D.J. Klionsky, L.M. Banta, and S.D. Emr. 1988. Protein sorting in Sacckaromyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol. Cell Biol. 8:4936-4948.
43. Rothman, J.E., and L. Orci. 1992. Molecular dissection of the secretory pathway. Nature. 355:409-415.
44. Rothman, J.E., and F.T. Wieland. 1996. Protein sorting by transport vesicles. Science. 272:227-234.
45. Rothman, J.H., C.K. Raymond, T. Gilbert, P.J. O'Hara, and T.H. Stevens. 1990. A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell. 61: 1063-1074.
46. Rothman, J.H., and T.H. Stevens. 1986. Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell. 47:1041-1051.
47. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual-Second Edition. Cold Spring Harbor Laboratory Press, Plainview, NY.
48. Schekman, R., and L. Orci. 1996. Coat proteins and vesicle budding. Science. 271:1526-1533.
49. Schweizer, A., S. Kornfeld, and J. Rohrer. 1997. Proper sorting of the cation-dependent mannose 6-phosphale receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail. Proc. Natl. Acad. Sci. USA. 94:14471-14476.
50. Seaman, M.N.J., E.G. Marcusson, J.-L. Cereghino, and S.D. Emr. 1997. Endosome-to-Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of VPS29, VPS30 and VPS35 gene products. J. Cell Biol. 137:79-92.
51. Seeger, M., and G.S. Payne. 1992a. A role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeast. EMBO (Eur. Mol. Biot. Organ.) J. 11:2811-2818.
52. Seeger, M., and G.S. Payne. 1992b. Selective and immediate effects of clathrin heavy chain Mutations on Golgi membrane protein retention in Saccharomyces cerevisiae. J. Cell Biol. 118:531-540.
53. Serafini, T., G. Stenbeck, A. Brecht, F. Lottspeich, L. Orci, J.E. Rothman, and F.T. Weiland. 1991. A coat subunit of Golgi-derived non clathrin-coated vesicles with homology to the clathrin-coated vesicle protein β-adaplin. Nature. 349:248-251.
54. Sherman, F., G.R. Fink, and L.W. Lawrence. 1979. Methods in Yeast Genetics: A Laboratory Manual. Cold Spring Harbor Laboratory, Plainview, NY.
55. Smith, D.B., and K.S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia colt as fusions with glutathione S-transferase. Gene. 67:31-40.
56. Takei, K., O. Mundigl, L. Daniell, and P. De Camilli. 1996. The synaptic vesicle cycle: a single vesicle budding step involving clalhrin and dynamin. J. Cell Biol. 133:1237-1250.
57. Traub, L.M., and S. Kornfeld. 1997. The trans-Golgi network: a late secretory sorting station. Curr. Opin. Cell Biol. 9:527-533.
58. Vater, C.A., C.K. Raymond, K. Ekena, I. Howald-Stevenson, and T.H. Stevens. 1992. The VPS1 protein, a homologue of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J. Cell Biol. 119:773-786.
59. Voos, W., and T.H. Stevens. 1998. Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Sacchortnyces cerevisiae is dependent upon the function of Grd19p. J. Cell Biol. 140:577-590.
60. Warnock, D.E., and S.L. Schmid. 1996. Dynamin GTPase, a force-generating molecular switch. Bioessays. 18:885-893.
61. Westphal, V., E.G. Marcusson, J.R. Winther, S.D. Emr, and H.B. van den Hazel. 1996. Multiple pathways for vacuolar sorting of yeast proteinase A. J. Biol. Chem. 271:11865-11870.
62. Wilcox, C.A., K. Redding, R. Wright, and R.S. Fuller. 1992. Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol. Biol. Cell. 3:1353-1371.
63. Wilsbach, K., and G.S. Payne. 1993a. Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae. EMBO (Eur. Mol. Biol. Organ.) J. 12:3049-3059.
64. Wilsbach, K., and G.S. Payne. 1993b. Dynamic retention of TGN membrane proteins in Saccharomyces cerevisiae. Trends Cell Biol. 3:426-432.