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Volumn 123, Issue 5, 2010, Pages 756-766

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

Author keywords

DMT1; Endosome; Iron metabolism; Recycling; Retromer; Transferrin cycle

Indexed keywords

CARRIER PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MUTANT PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2 II; RETROMER; SMALL INTERFERING RNA; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 77149155327     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.060574     Document Type: Article
Times cited : (125)

References (49)
  • 1
    • 0033599057 scopus 로고    scopus 로고
    • Disorders of iron metabolism
    • Andrews, N. C. (1999). Disorders of iron metabolism. N. Engl. J. Med. 341, 1986-1995.
    • (1999) N. Engl. J. Med , vol.341 , pp. 1986-1995
    • Andrews, N.C.1
  • 2
    • 47649126246 scopus 로고    scopus 로고
    • Forging a field: The golden age of iron biology
    • Andrews, N. C. (2008). Forging a field: the golden age of iron biology. Blood 112, 219-230.
    • (2008) Blood , vol.112 , pp. 219-230
    • Andrews, N.C.1
  • 3
    • 2442530398 scopus 로고    scopus 로고
    • Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
    • Arighi, C. N., Hartnell, L. M., Aguilar, R. C., Haft, C. R. and Bonifacino, J. S. (2004). Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J. Cell Biol. 165, 123-133.
    • (2004) J. Cell Biol , vol.165 , pp. 123-133
    • Arighi, C.N.1    Hartnell, L.M.2    Aguilar, R.C.3    Haft, C.R.4    Bonifacino, J.S.5
  • 4
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte, S. and Cordelieres, F. P. (2006). A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232.
    • (2006) J. Microsc , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelieres, F.P.2
  • 5
    • 0038795645 scopus 로고    scopus 로고
    • Signals for sorting of transmembrane proteins to endosomes and lysosomes
    • Bonifacino, J. S. and Traub, L. M. (2003). Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem. 72, 395-447.
    • (2003) Annu. Rev. Biochem , vol.72 , pp. 395-447
    • Bonifacino, J.S.1    Traub, L.M.2
  • 6
    • 33748313351 scopus 로고    scopus 로고
    • Retrograde transport from endosomes to the trans-Golgi network
    • Bonifacino, J. S. and Rojas, R. (2006). Retrograde transport from endosomes to the trans-Golgi network. Nat. Rev. Mol. Cell. Biol. 7, 568-579.
    • (2006) Nat. Rev. Mol. Cell. Biol , vol.7 , pp. 568-579
    • Bonifacino, J.S.1    Rojas, R.2
  • 8
    • 0033564656 scopus 로고    scopus 로고
    • Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron
    • Canonne-Hergaux, F., Gruenheid, S., Ponka, P. and Gros, P. (1999). Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood 93, 4406-4417.
    • (1999) Blood , vol.93 , pp. 4406-4417
    • Canonne-Hergaux, F.1    Gruenheid, S.2    Ponka, P.3    Gros, P.4
  • 9
    • 0035895096 scopus 로고    scopus 로고
    • Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice
    • Canonne-Hergaux, F., Zhang, A. S., Ponka, P. and Gros, P. (2001). Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. Blood 98, 3823-3830.
    • (2001) Blood , vol.98 , pp. 3823-3830
    • Canonne-Hergaux, F.1    Zhang, A.S.2    Ponka, P.3    Gros, P.4
  • 10
    • 6944255481 scopus 로고    scopus 로고
    • Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides
    • Carlton, J., Bujny, M., Peter, B. J., Oorschot, V. M., Rutherford, A., Mellor, H., Klumperman, J., McMahon, H. T. and Cullen, P. J. (2004). Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides. Curr. Biol. 14, 1791-1800.
    • (2004) Curr. Biol , vol.14 , pp. 1791-1800
    • Carlton, J.1    Bujny, M.2    Peter, B.J.3    Oorschot, V.M.4    Rutherford, A.5    Mellor, H.6    Klumperman, J.7    McMahon, H.T.8    Cullen, P.J.9
  • 11
    • 53849101821 scopus 로고    scopus 로고
    • The structure and function of the retromer protein complex
    • Collins, B. M. (2008). The structure and function of the retromer protein complex. Traffic 9, 1811-1822.
    • (2008) Traffic , vol.9 , pp. 1811-1822
    • Collins, B.M.1
  • 12
    • 37748999044 scopus 로고    scopus 로고
    • Retromer retrieves wntless
    • Eaton, S. (2008). Retromer retrieves wntless. Dev. Cell 14, 4-6.
    • (2008) Dev. Cell , vol.14 , pp. 4-6
    • Eaton, S.1
  • 13
    • 0030763856 scopus 로고    scopus 로고
    • Fleming, M. D., Trenor, C. C., 3rd, Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F. and Andrews, N. C. (1997). Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat. Genet. 16, 383-386.
    • Fleming, M. D., Trenor, C. C., 3rd, Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F. and Andrews, N. C. (1997). Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat. Genet. 16, 383-386.
  • 14
    • 0032477866 scopus 로고    scopus 로고
    • Nramp2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
    • Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D. and Andrews, N. C. (1998). Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc. Natl. Acad. Sci. USA 95, 1148-1153.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1148-1153
    • Fleming, M.D.1    Romano, M.A.2    Su, M.A.3    Garrick, L.M.4    Garrick, M.D.5    Andrews, N.C.6
  • 15
    • 0037336348 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptors: New twists in the tale
    • Ghosh, P., Dahms, N. M. and Kornfeld, S. (2003). Mannose 6-phosphate receptors: new twists in the tale. Nat. Rev. Mol. Cell. Biol. 4, 202-212.
    • (2003) Nat. Rev. Mol. Cell. Biol , vol.4 , pp. 202-212
    • Ghosh, P.1    Dahms, N.M.2    Kornfeld, S.3
  • 16
    • 35948954976 scopus 로고    scopus 로고
    • Identification of a conserved motif required for Vps35p/Vps26p interaction and assembly of the retromer complex
    • Gokool, S., Tattersall, D., Reddy, J. V. and Seaman, M. N. (2007). Identification of a conserved motif required for Vps35p/Vps26p interaction and assembly of the retromer complex. Biochem. J. 408, 287-295.
    • (2007) Biochem. J , vol.408 , pp. 287-295
    • Gokool, S.1    Tattersall, D.2    Reddy, J.V.3    Seaman, M.N.4
  • 17
    • 0033103978 scopus 로고    scopus 로고
    • The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes
    • Gruenheid, S., Canonne-Hergaux, F., Gauthier, S., Hackam, D. J., Grinstein, S. and Gros, P. (1999). The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. J. Exp. Med. 189, 831-841.
    • (1999) J. Exp. Med , vol.189 , pp. 831-841
    • Gruenheid, S.1    Canonne-Hergaux, F.2    Gauthier, S.3    Hackam, D.J.4    Grinstein, S.5    Gros, P.6
  • 19
    • 0037126002 scopus 로고    scopus 로고
    • Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
    • Hubert, N. and Hentze, M. W. (2002). Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc. Natl. Acad. Sci. USA 99, 12345-12350.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12345-12350
    • Hubert, N.1    Hentze, M.W.2
  • 20
    • 0025847213 scopus 로고
    • A simple and rapid method for generating a deletion by PCR
    • Imai, Y., Matsushima, Y., Sugimura, T. and Terada, M. (1991). A simple and rapid method for generating a deletion by PCR. Nucleic Acids Res. 19, 2785.
    • (1991) Nucleic Acids Res , vol.19 , pp. 2785
    • Imai, Y.1    Matsushima, Y.2    Sugimura, T.3    Terada, M.4
  • 21
    • 0036902646 scopus 로고    scopus 로고
    • Receptor downregulation and multivesicular-body sorting
    • Katzmann, D. J., Odorizzi, G. and Emr, S. D. (2002). Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell. Biol. 3, 893-905.
    • (2002) Nat. Rev. Mol. Cell. Biol , vol.3 , pp. 893-905
    • Katzmann, D.J.1    Odorizzi, G.2    Emr, S.D.3
  • 22
    • 33144468560 scopus 로고    scopus 로고
    • Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2)
    • Lam-Yuk-Tseung, S. and Gros, P. (2006). Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2). Biochemistry 45, 2294-2301.
    • (2006) Biochemistry , vol.45 , pp. 2294-2301
    • Lam-Yuk-Tseung, S.1    Gros, P.2
  • 23
    • 24644489085 scopus 로고    scopus 로고
    • Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes
    • Lam-Yuk-Tseung, S., Touret, N., Grinstein, S. and Gros, P. (2005). Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry 44, 12149-12159.
    • (2005) Biochemistry , vol.44 , pp. 12149-12159
    • Lam-Yuk-Tseung, S.1    Touret, N.2    Grinstein, S.3    Gros, P.4
  • 24
    • 0032104739 scopus 로고    scopus 로고
    • The human Nramp2 gene: Characterization of the gene structure, alternative splicing, promoter region and polymorphisms
    • Lee, P. L., Gelbart, T., West, C., Halloran, C. and Beutler, E. (1998). The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms. Blood Cells Mol. Dis. 24, 199-215.
    • (1998) Blood Cells Mol. Dis , vol.24 , pp. 199-215
    • Lee, P.L.1    Gelbart, T.2    West, C.3    Halloran, C.4    Beutler, E.5
  • 25
    • 67649882015 scopus 로고    scopus 로고
    • Identification of a cytoplasmic signal for apical transcytosis
    • Luton, F., Hexham, M. J., Zhang, M. and Mostov, K. E. (2009). Identification of a cytoplasmic signal for apical transcytosis. Traffic 10, 1128-1142.
    • (2009) Traffic , vol.10 , pp. 1128-1142
    • Luton, F.1    Hexham, M.J.2    Zhang, M.3    Mostov, K.E.4
  • 26
    • 28444476999 scopus 로고    scopus 로고
    • Membrane curvature and mechanisms of dynamic cell membrane remodelling
    • McMahon, H. T. and Gallop, J. L. (2005). Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 438, 590-596.
    • (2005) Nature , vol.438 , pp. 590-596
    • McMahon, H.T.1    Gallop, J.L.2
  • 27
    • 0034675999 scopus 로고    scopus 로고
    • Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p
    • Nothwehr, S. F., Ha, S. A. and Bruinsma, P. (2000). Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p. J. Cell Biol. 151, 297-310.
    • (2000) J. Cell Biol , vol.151 , pp. 297-310
    • Nothwehr, S.F.1    Ha, S.A.2    Bruinsma, P.3
  • 29
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • Rink, J., Ghigo, E., Kalaidzidis, Y. and Zerial, M. (2005). Rab conversion as a mechanism of progression from early to late endosomes. Cell 122, 735-749.
    • (2005) Cell , vol.122 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 31
    • 2442509574 scopus 로고    scopus 로고
    • Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer
    • Seaman, M. N. (2004). Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J. Cell Biol. 165, 111-122.
    • (2004) J. Cell Biol , vol.165 , pp. 111-122
    • Seaman, M.N.1
  • 32
    • 13244275069 scopus 로고    scopus 로고
    • Recycle your receptors with retromer
    • Seaman, M. N. (2005). Recycle your receptors with retromer. Trends Cell Biol. 15, 68-75.
    • (2005) Trends Cell Biol , vol.15 , pp. 68-75
    • Seaman, M.N.1
  • 33
    • 34547796509 scopus 로고    scopus 로고
    • Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval
    • Seaman, M. N. (2007). Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval. J. Cell Sci. 120, 2378-2389.
    • (2007) J. Cell Sci , vol.120 , pp. 2378-2389
    • Seaman, M.N.1
  • 34
    • 52549127726 scopus 로고    scopus 로고
    • Endosome protein sorting: Motifs and machinery
    • Seaman, M. N. (2008). Endosome protein sorting: motifs and machinery. Cell Mol. Life Sci. 65, 2842-2858.
    • (2008) Cell Mol. Life Sci , vol.65 , pp. 2842-2858
    • Seaman, M.N.1
  • 35
    • 0031823307 scopus 로고    scopus 로고
    • A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast
    • Seaman, M. N., McCaffery, J. M. and Emr, S. D. (1998). A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J. Cell Biol. 142, 665-681.
    • (1998) J. Cell Biol , vol.142 , pp. 665-681
    • Seaman, M.N.1    McCaffery, J.M.2    Emr, S.D.3
  • 36
    • 69649083104 scopus 로고    scopus 로고
    • Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5
    • Seaman, M. N., Harbour, M. E., Tattersall, D., Read, E. and Bright, N. (2009). Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5. J. Cell Sci. 122, 2371-2382.
    • (2009) J. Cell Sci , vol.122 , pp. 2371-2382
    • Seaman, M.N.1    Harbour, M.E.2    Tattersall, D.3    Read, E.4    Bright, N.5
  • 37
    • 58749094789 scopus 로고    scopus 로고
    • Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency
    • Shah, Y. M., Matsubara, T., Ito, S., Yim, S. H. and Gonzalez, F. J. (2009). Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency. Cell Metab. 9, 152-164.
    • (2009) Cell Metab , vol.9 , pp. 152-164
    • Shah, Y.M.1    Matsubara, T.2    Ito, S.3    Yim, S.H.4    Gonzalez, F.J.5
  • 38
    • 34247143246 scopus 로고    scopus 로고
    • Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling
    • Strochlic, T. I., Setty, T. G., Sitaram, A. and Burd, C. G. (2007). Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling. J. Cell Biol. 177, 115-125.
    • (2007) J. Cell Biol , vol.177 , pp. 115-125
    • Strochlic, T.I.1    Setty, T.G.2    Sitaram, A.3    Burd, C.G.4
  • 39
    • 0032530922 scopus 로고    scopus 로고
    • The G185R mutation disrupts function of the iron transporter Nramp2
    • Su, M. A., Trenor, C. C., Fleming, J. C., Fleming, M. D. and Andrews, N. C. (1998). The G185R mutation disrupts function of the iron transporter Nramp2. Blood 92, 2157-2163.
    • (1998) Blood , vol.92 , pp. 2157-2163
    • Su, M.A.1    Trenor, C.C.2    Fleming, J.C.3    Fleming, M.D.4    Andrews, N.C.5
  • 40
    • 0034698023 scopus 로고    scopus 로고
    • Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells
    • Tabuchi, M., Yoshimori, T., Yamaguchi, K., Yoshida, T. and Kishi, F. (2000). Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells. J. Biol. Chem. 275, 22220-22228.
    • (2000) J. Biol. Chem , vol.275 , pp. 22220-22228
    • Tabuchi, M.1    Yoshimori, T.2    Yamaguchi, K.3    Yoshida, T.4    Kishi, F.5
  • 41
    • 0036906608 scopus 로고    scopus 로고
    • Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms
    • Tabuchi, M., Tanaka, N., Nishida-Kitayama, J., Ohno, H. and Kishi, F. (2002). Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms. Mol. Biol. Cell 13, 4371-4387.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4371-4387
    • Tabuchi, M.1    Tanaka, N.2    Nishida-Kitayama, J.3    Ohno, H.4    Kishi, F.5
  • 42
    • 0035958856 scopus 로고    scopus 로고
    • Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains
    • Takatsu, H., Katoh, Y., Shiba, Y. and Nakayama, K. (2001). Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains. J. Biol. Chem. 276, 28541-28545.
    • (2001) J. Biol. Chem , vol.276 , pp. 28541-28545
    • Takatsu, H.1    Katoh, Y.2    Shiba, Y.3    Nakayama, K.4
  • 43
    • 0038491413 scopus 로고    scopus 로고
    • Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor
    • Touret, N., Furuya, W., Forbes, J., Gros, P. and Grinstein, S. (2003). Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J. Biol. Chem. 278, 25548-25557.
    • (2003) J. Biol. Chem , vol.278 , pp. 25548-25557
    • Touret, N.1    Furuya, W.2    Forbes, J.3    Gros, P.4    Grinstein, S.5
  • 46
  • 47
    • 37749043874 scopus 로고    scopus 로고
    • Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells
    • Yang, P. T., Lorenowicz, M. J., Silhankova, M., Coudreuse, D. Y., Betist, M. C. and Korswagen, H. C. (2008). Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells. Dev. Cell 14, 140-147.
    • (2008) Dev. Cell , vol.14 , pp. 140-147
    • Yang, P.T.1    Lorenowicz, M.J.2    Silhankova, M.3    Coudreuse, D.Y.4    Betist, M.C.5    Korswagen, H.C.6
  • 48
    • 0024059354 scopus 로고
    • Binding properties of monoclonal antibody to the cytoplasmic domain of transferrin receptor
    • Yoshimori, T., Shimonishi, Y. and Uchida, T. (1988). Binding properties of monoclonal antibody to the cytoplasmic domain of transferrin receptor. Cell Struct. Funct. 13, 311-324.
    • (1988) Cell Struct. Funct , vol.13 , pp. 311-324
    • Yoshimori, T.1    Shimonishi, Y.2    Uchida, T.3
  • 49
    • 0035369692 scopus 로고    scopus 로고
    • Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor
    • Zhu, Y., Doray, B., Poussu, A., Lehto, V. P. and Kornfeld, S. (2001). Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor. Science 292, 1716-1718.
    • (2001) Science , vol.292 , pp. 1716-1718
    • Zhu, Y.1    Doray, B.2    Poussu, A.3    Lehto, V.P.4    Kornfeld, S.5


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