-
1
-
-
84924787042
-
Targeting host-derived glycans on enveloped viruses for antibody-based vaccine design
-
Crispin M, Doores KJ. 2015. Targeting host-derived glycans on enveloped viruses for antibody-based vaccine design. Curr Opin Virol 11:63-69 http://dx.doi.org/10.1016/j.coviro.2015.02.002.
-
(2015)
Curr Opin Virol
, vol.11
, pp. 63-69
-
-
Crispin, M.1
Doores, K.J.2
-
2
-
-
84959117772
-
The HIV glycan shield as a target for broadly neutralizing antibodies
-
Doores KJ. 2015. The HIV glycan shield as a target for broadly neutralizing antibodies. FEBS J 282:4679-4691. http://dx.doi.org/10.1111/febs.13530.
-
(2015)
FEBS J
, vol.282
, pp. 4679-4691
-
-
Doores, K.J.1
-
3
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
Wei X, Decker JM, Wang S, Hui H, Kappes JC, Wu X, Salazar-Gonzalez JF, Salazar MG, Kilby JM, Saag MS, Komarova NL, Nowak MA, Hahn BH, Kwong PD, Shaw GM. 2003. Antibody neutralization and escape by HIV-1. Nature 422:307-312. http://dx.doi.org/10.1038/nature01470.
-
(2003)
Nature
, vol.422
, pp. 307-312
-
-
Wei, X.1
Decker, J.M.2
Wang, S.3
Hui, H.4
Kappes, J.C.5
Wu, X.6
Salazar-Gonzalez, J.F.7
Salazar, M.G.8
Kilby, J.M.9
Saag, M.S.10
Komarova, N.L.11
Nowak, M.A.12
Hahn, B.H.13
Kwong, P.D.14
Shaw, G.M.15
-
4
-
-
18244422922
-
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1→2 mannose residues on the outer face of gp120
-
Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR. 2002. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1→2 mannose residues on the outer face of gp120. J Virol 76:7306-7321. http://dx.doi.org/10.1128/JVI.76.14.7306-7321.2002.
-
(2002)
J Virol
, vol.76
, pp. 7306-7321
-
-
Scanlan, C.N.1
Pantophlet, R.2
Wormald, M.R.3
Ollmann Saphire, E.4
Stanfield, R.5
Wilson, I.A.6
Katinger, H.7
Dwek, R.A.8
Rudd, P.M.9
Burton, D.R.10
-
5
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, Wong CH, Phogat S, Wrin T, Simek MD, Koff WC, Wilson IA, Burton DR, Poignard P. 2011. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 477:466-470. http://dx.doi.org/10.1038/nature10373.
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
Falkowska, E.4
Pejchal, R.5
Julien, J.P.6
Wang, S.K.7
Ramos, A.8
Chan-Hui, P.Y.9
Moyle, M.10
Mitcham, J.L.11
Hammond, P.W.12
Olsen, O.A.13
Phung, P.14
Fling, S.15
Wong, C.H.16
Phogat, S.17
Wrin, T.18
Simek, M.D.19
Koff, W.C.20
Wilson, I.A.21
Burton, D.R.22
Poignard, P.23
more..
-
6
-
-
34247636624
-
Exploiting the defensive sugars of HIV-1 for drug and vaccine design
-
Scanlan CN, Offer J, Zitzmann N, Dwek RA. 2007. Exploiting the defensive sugars of HIV-1 for drug and vaccine design. Nature 446:1038-1045 http://dx.doi.org/10.1038/nature05818.
-
(2007)
Nature
, vol.446
, pp. 1038-1045
-
-
Scanlan, C.N.1
Offer, J.2
Zitzmann, N.3
Dwek, R.A.4
-
7
-
-
77956385205
-
Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens
-
Doores KJ, Bonomelli C, Harvey DJ, Vasiljevic S, Dwek RA, Burton DR, Crispin M, Scanlan CN. 2010. Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens. Proc Natl Acad Sci U S A 107:13800-13805. http://dx.doi.org/10.1073/pnas.1006498107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13800-13805
-
-
Doores, K.J.1
Bonomelli, C.2
Harvey, D.J.3
Vasiljevic, S.4
Dwek, R.A.5
Burton, D.R.6
Crispin, M.7
Scanlan, C.N.8
-
8
-
-
45549101708
-
Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility
-
Go EP, Irungu J, Zhang Y, Dalpathado DS, Liao HX, Sutherland LL, Alam SM, Haynes BF, Desaire H. 2008. Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility. J Proteome Res 7:1660-1674. http://dx.doi.org/10.1021/pr7006957.
-
(2008)
J Proteome Res
, vol.7
, pp. 1660-1674
-
-
Go, E.P.1
Irungu, J.2
Zhang, Y.3
Dalpathado, D.S.4
Liao, H.X.5
Sutherland, L.L.6
Alam, S.M.7
Haynes, B.F.8
Desaire, H.9
-
9
-
-
0024232268
-
Structural characterization by chromatographic profiling of the oligosaccharides of human immunodeficiency virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinese hamster ovary cells
-
Mizuochi T, Spellman MW, Larkin M, Solomon J, Basa LJ, Feizi T. 1988 Structural characterization by chromatographic profiling of the oligosaccharides of human immunodeficiency virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinese hamster ovary cells. Biomed Chromatogr 2:260-270.
-
(1988)
Biomed Chromatogr
, vol.2
, pp. 260-270
-
-
Mizuochi, T.1
Spellman, M.W.2
Larkin, M.3
Solomon, J.4
Basa, L.J.5
Feizi, T.6
-
10
-
-
0023807495
-
Carbohydrate structures of the human-immunodeficiency-virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinesehamster ovary cells
-
Mizuochi T, Spellman MW, Larkin M, Solomon J, Basa LJ, Feizi T. 1988 Carbohydrate structures of the human-immunodeficiency-virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinesehamster ovary cells. Biochem J 254:599-603. http://dx.doi.org/10.1042 /bj2540599.
-
(1988)
Biochem J
, vol.254
, pp. 599-603
-
-
Mizuochi, T.1
Spellman, M.W.2
Larkin, M.3
Solomon, J.4
Basa, L.J.5
Feizi, T.6
-
11
-
-
0034687168
-
Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells
-
Zhu X, Borchers C, Bienstock RJ, Tomer KB. 2000. Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells. Biochemistry 39:11194-11204. http://dx.doi.org/10.1021 /bi000432m.
-
(2000)
Biochemistry
, vol.39
, pp. 11194-11204
-
-
Zhu, X.1
Borchers, C.2
Bienstock, R.J.3
Tomer, K.B.4
-
12
-
-
0025374887
-
Diversity of oligosaccharide structures on the envelope glycoprotein gp 120 of human immunodeficiency virus 1 from the lymphoblastoid cell line H9. Presence of complex-type oligosaccharides with bisecting N-acetylglucosamine residues
-
Mizuochi T, Matthews TJ, Kato M, Hamako J, Titani K, Solomon J, Feizi T. 1990. Diversity of oligosaccharide structures on the envelope glycoprotein gp 120 of human immunodeficiency virus 1 from the lymphoblastoid cell line H9. Presence of complex-type oligosaccharides with bisecting N-acetylglucosamine residues. J Biol Chem 265:8519-8524.
-
(1990)
J Biol Chem
, vol.265
, pp. 8519-8524
-
-
Mizuochi, T.1
Matthews, T.J.2
Kato, M.3
Hamako, J.4
Titani, K.5
Solomon, J.6
Feizi, T.7
-
13
-
-
0023811767
-
Carbohydrates of human immunodeficiency viru. Structures of oligosaccharides linked to the envelope glycoprotein 120
-
Geyer H, Holschbach C, Hunsmann G, Schneider J. 1988. Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein 120. J Biol Chem 263:11760-11767.
-
(1988)
J Biol Chem
, vol.263
, pp. 11760-11767
-
-
Geyer, H.1
Holschbach, C.2
Hunsmann, G.3
Schneider, J.4
-
14
-
-
0025292252
-
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
-
Leonard CK, Spellman MW, Riddle L, Harris RJ, Thomas JN, Gregory TJ. 1990. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J Biol Chem 265:10373-10382.
-
(1990)
J Biol Chem
, vol.265
, pp. 10373-10382
-
-
Leonard, C.K.1
Spellman, M.W.2
Riddle, L.3
Harris, R.J.4
Thomas, J.N.5
Gregory, T.J.6
-
15
-
-
80051677678
-
The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade
-
Bonomelli C, Doores KJ, Dunlop DC, Thaney V, Dwek RA, Burton DR, Crispin M, Scanlan CN. 2011. The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade. PLoS One 6:e23521. http://dx.doi.org/10.1371/journal.pone.0023521.
-
(2011)
PLoS One
, vol.6
-
-
Bonomelli, C.1
Doores, K.J.2
Dunlop, D.C.3
Thaney, V.4
Dwek, R.A.5
Burton, D.R.6
Crispin, M.7
Scanlan, C.N.8
-
16
-
-
84933074280
-
Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies
-
Pritchard LK, Spencer DI, Royle L, Bonomelli C, Seabright GE, Behrens AJ, Kulp DW, Menis S, Krumm SA, Dunlop DC, Crispin DJ, Bowden TA, Scanlan CN, Ward AB, Schief WR, Doores KJ, Crispin M. 2015. Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies. Nat Commun 6:7479. http://dx.doi.org/10.1038/ncomms8479.
-
(2015)
Nat Commun
, vol.6
, pp. 7479
-
-
Pritchard, L.K.1
Spencer, D.I.2
Royle, L.3
Bonomelli, C.4
Seabright, G.E.5
Behrens, A.J.6
Kulp, D.W.7
Menis, S.8
Krumm, S.A.9
Dunlop, D.C.10
Crispin, D.J.11
Bowden, T.A.12
Scanlan, C.N.13
Ward, A.B.14
Schief, W.R.15
Doores, K.J.16
Crispin, M.17
-
17
-
-
84938924964
-
Cell-and protein-directed glycosylation of native cleaved HIV-1 envelope
-
Pritchard LK, Harvey DJ, Bonomelli C, Crispin M, Doores KJ. 2015. Cell-and protein-directed glycosylation of native cleaved HIV-1 envelope. J Virol 89:8932-8944. http://dx.doi.org/10.1128/JVI.01190-15.
-
(2015)
J Virol
, vol.89
, pp. 8932-8944
-
-
Pritchard, L.K.1
Harvey, D.J.2
Bonomelli, C.3
Crispin, M.4
Doores, K.J.5
-
18
-
-
84937641486
-
Structural constraints determine the glycosylation of HIV-1 envelope trimers
-
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe RP, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. 2015. Structural constraints determine the glycosylation of HIV-1 envelope trimers. Cell Rep 11:1604-1613. http://dx.doi.org/10.1016/j.celrep.2015.05.017.
-
(2015)
Cell Rep
, vol.11
, pp. 1604-1613
-
-
Pritchard, L.K.1
Vasiljevic, S.2
Ozorowski, G.3
Seabright, G.E.4
Cupo, A.5
Ringe, R.P.6
Kim, H.J.7
Sanders, R.W.8
Doores, K.J.9
Burton, D.R.10
Wilson, I.A.11
Ward, A.B.12
Moore, J.P.13
Crispin, M.14
-
19
-
-
84874622598
-
Characterization of host-cell line specific glycosylation profiles of early transmitted/founder HIV-1 gp120 envelope proteins
-
Go EP, Liao HX, Alam SM, Hua D, Haynes BF, Desaire H. 2013. Characterization of host-cell line specific glycosylation profiles of early transmitted/founder HIV-1 gp120 envelope proteins. J Proteome Res 12: 1223-1234. http://dx.doi.org/10.1021/pr300870t.
-
(2013)
J Proteome Res
, vol.12
, pp. 1223-1234
-
-
Go, E.P.1
Liao, H.X.2
Alam, S.M.3
Hua, D.4
Haynes, B.F.5
Desaire, H.6
-
20
-
-
84938149437
-
Comparative analysis of the glycosylation profiles of membrane-anchored HIV-1 envelope glycoprotein trimers and soluble gp140
-
Go EP, Herschhorn A, Gu C, Castillo-Menendez L, Zhang S, Mao Y, Chen H, Ding H, Wakefield JK, Hua D, Liao HX, Kappes JC, Sodroski J, Desaire H. 2015. Comparative analysis of the glycosylation profiles of membrane-anchored HIV-1 envelope glycoprotein trimers and soluble gp140. J Virol 89:8245-8257. http://dx.doi.org/10.1128/JVI.00628-15.
-
(2015)
J Virol
, vol.89
, pp. 8245-8257
-
-
Go, E.P.1
Herschhorn, A.2
Gu, C.3
Castillo-Menendez, L.4
Zhang, S.5
Mao, Y.6
Chen, H.7
Ding, H.8
Wakefield, J.K.9
Hua, D.10
Liao, H.X.11
Kappes, J.C.12
Sodroski, J.13
Desaire, H.14
-
21
-
-
84986628335
-
Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding
-
Panico M, Bouche L, Binet D, O'Connor MJ, Rahman D, Pang PC, Canis K, North SJ, Desrosiers RC, Chertova E, Keele BF, Bess JW, Jr, Lifson JD, Haslam SM, Dell A, Morris HR. 2016. Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding. Sci Rep 6:32956. http://dx.doi.org /10.1038/srep32956.
-
(2016)
Sci Rep
, vol.6
, pp. 32956
-
-
Panico, M.1
Bouche, L.2
Binet, D.3
O'Connor, M.J.4
Rahman, D.5
Pang, P.C.6
Canis, K.7
North, S.J.8
Desrosiers, R.C.9
Chertova, E.10
Keele, B.F.11
Bess, J.W.12
Lifson, J.D.13
Haslam, S.M.14
Dell, A.15
Morris, H.R.16
-
22
-
-
84959932564
-
Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein
-
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, Klasse PJ, Burton DR, Wilson IA, Ward AB, Sanders RW, Moore JP, Doores KJ, Crispin M. 2016. Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein. Cell Rep 14:2695-2706. http://dx.doi.org/10.1016 /j.celrep.2016.02.058.
-
(2016)
Cell Rep
, vol.14
, pp. 2695-2706
-
-
Behrens, A.J.1
Vasiljevic, S.2
Pritchard, L.K.3
Harvey, D.J.4
Andev, R.S.5
Krumm, S.A.6
Struwe, W.B.7
Cupo, A.8
Kumar, A.9
Zitzmann, N.10
Seabright, G.E.11
Kramer, H.B.12
Spencer, D.I.13
Royle, L.14
Lee, J.H.15
Klasse, P.J.16
Burton, D.R.17
Wilson, I.A.18
Ward, A.B.19
Sanders, R.W.20
Moore, J.P.21
Doores, K.J.22
Crispin, M.23
more..
-
23
-
-
84880161438
-
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
-
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, Khayat R, Deller MC, Clayton T, Tien H, Feizi T, Sanders RW, Paulson JC, Moore JP, Stanfield RL, Burton DR, Ward AB, Wilson IA. 2013. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat Struct Mol Biol 20:796-803. http://dx.doi.org/10.1038/nsmb.2594.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 796-803
-
-
Kong, L.1
Lee, J.H.2
Doores, K.J.3
Murin, C.D.4
Julien, J.P.5
McBride, R.6
Liu, Y.7
Marozsan, A.8
Cupo, A.9
Klasse, P.J.10
Hoffenberg, S.11
Caulfield, M.12
King, C.R.13
Hua, Y.14
Le, K.M.15
Khayat, R.16
Deller, M.C.17
Clayton, T.18
Tien, H.19
Feizi, T.20
Sanders, R.W.21
Paulson, J.C.22
Moore, J.P.23
Stanfield, R.L.24
Burton, D.R.25
Ward, A.B.26
Wilson, I.A.27
more..
-
24
-
-
84869831194
-
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
-
Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ. 2012. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proc Natl Acad Sci U S A 109:E3268-E3277. http://dx.doi.org/10.1073/pnas.1217207109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E3268-E3277
-
-
Mouquet, H.1
Scharf, L.2
Euler, Z.3
Liu, Y.4
Eden, C.5
Scheid, J.F.6
Halper-Stromberg, A.7
Gnanapragasam, P.N.8
Spencer, D.I.9
Seaman, M.S.10
Schuitemaker, H.11
Feizi, T.12
Nussenzweig, M.C.13
Bjorkman, P.J.14
-
25
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, Liu Y, McBride R, Ito Y, Sanders RW, Ogohara C, Paulson JC, Feizi T, Scanlan CN, Wong CH, Moore JP, Olson WC, Ward AB, Poignard P, Schief WR, Burton DR, Wilson IA. 2011. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science 334:1097-1103. http://dx.doi.org /10.1126/science.1213256.
-
(2011)
Science
, vol.334
, pp. 1097-1103
-
-
Pejchal, R.1
Doores, K.J.2
Walker, L.M.3
Khayat, R.4
Huang, P.S.5
Wang, S.K.6
Stanfield, R.L.7
Julien, J.P.8
Ramos, A.9
Crispin, M.10
Depetris, R.11
Katpally, U.12
Marozsan, A.13
Cupo, A.14
Maloveste, S.15
Liu, Y.16
McBride, R.17
Ito, Y.18
Sanders, R.W.19
Ogohara, C.20
Paulson, J.C.21
Feizi, T.22
Scanlan, C.N.23
Wong, C.H.24
Moore, J.P.25
Olson, W.C.26
Ward, A.B.27
Poignard, P.28
Schief, W.R.29
Burton, D.R.30
Wilson, I.A.31
more..
-
26
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, Wrin T, Simek MD, Fling S, Mitcham JL, Lehrman JK, Priddy FH, Olsen OA, Frey SM, Hammond PW, Kaminsky S, Zamb T, Moyle M, Koff WC, Poignard P, Burton DR. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289. http://dx.doi.org/10.1126/science.1178746.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
Wagner, D.4
Phung, P.5
Goss, J.L.6
Wrin, T.7
Simek, M.D.8
Fling, S.9
Mitcham, J.L.10
Lehrman, J.K.11
Priddy, F.H.12
Olsen, O.A.13
Frey, S.M.14
Hammond, P.W.15
Kaminsky, S.16
Zamb, T.17
Moyle, M.18
Koff, W.C.19
Poignard, P.20
Burton, D.R.21
more..
-
27
-
-
84953896553
-
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency
-
Doria-Rose NA, Bhiman JN, Roark RS, Schramm CA, Gorman J, Chuang GY, Pancera M, Cale EM, Ernandes MJ, Louder MK, Asokan M, Bailer RT, Druz A, Fraschilla IR, Garrett NJ, Jarosinski M, Lynch RM, McKee K, O'Dell S, Pegu A, Schmidt SD, Staupe RP, Sutton MS, Wang K, Wibmer CK, Haynes BF, Abdool-Karim S, Shapiro L, Kwong PD, Moore PL, Morris L, Mascola JR. 2016. New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency. J Virol 90:76-91. http://dx.doi.org/10.1128/JVI.01791-15.
-
(2016)
J Virol
, vol.90
, pp. 76-91
-
-
Doria-Rose, N.A.1
Bhiman, J.N.2
Roark, R.S.3
Schramm, C.A.4
Gorman, J.5
Chuang, G.Y.6
Pancera, M.7
Cale, E.M.8
Ernandes, M.J.9
Louder, M.K.10
Asokan, M.11
Bailer, R.T.12
Druz, A.13
Fraschilla, I.R.14
Garrett, N.J.15
Jarosinski, M.16
Lynch, R.M.17
McKee, K.18
O'Dell, S.19
Pegu, A.20
Schmidt, S.D.21
Staupe, R.P.22
Sutton, M.S.23
Wang, K.24
Wibmer, C.K.25
Haynes, B.F.26
Abdool-Karim, S.27
Shapiro, L.28
Kwong, P.D.29
Moore, P.L.30
Morris, L.31
Mascola, J.R.32
more..
-
28
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
Bonsignori M, Hwang KK, Chen X, Tsao CY, Morris L, Gray E, Marshall DJ, Crump JA, Kapiga SH, Sam NE, Sinangil F, Pancera M, Yongping Y, Zhang B, Zhu J, Kwong PD, O'Dell S, Mascola JR, Wu L, Nabel GJ, Phogat S, Seaman MS, Whitesides JF, Moody MA, Kelsoe G, Yang X, Sodroski J, Shaw GM, Montefiori DC, Kepler TB, Tomaras GD, Alam SM, Liao HX, Haynes BF. 2011. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J Virol 85:9998-10009. http://dx.doi.org/10.1128/JVI.05045-11.
-
(2011)
J Virol
, vol.85
, pp. 9998-10009
-
-
Bonsignori, M.1
Hwang, K.K.2
Chen, X.3
Tsao, C.Y.4
Morris, L.5
Gray, E.6
Marshall, D.J.7
Crump, J.A.8
Kapiga, S.H.9
Sam, N.E.10
Sinangil, F.11
Pancera, M.12
Yongping, Y.13
Zhang, B.14
Zhu, J.15
Kwong, P.D.16
O'Dell, S.17
Mascola, J.R.18
Wu, L.19
Nabel, G.J.20
Phogat, S.21
Seaman, M.S.22
Whitesides, J.F.23
Moody, M.A.24
Kelsoe, G.25
Yang, X.26
Sodroski, J.27
Shaw, G.M.28
Montefiori, D.C.29
Kepler, T.B.30
Tomaras, G.D.31
Alam, S.M.32
Liao, H.X.33
Haynes, B.F.34
more..
-
29
-
-
84900517557
-
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers
-
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, McBride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, Liu Y, Feizi T, Zwick MB, Koff WC, Seaman MS, Swiderek K, Moore JP, Evans D, Paulson JC, Wong CH, Ward AB, Wilson IA, Sanders RW, Poignard P, Burton DR. 2014. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers. Immunity 40:657-668. http://dx.doi.org/10.1016/j.immuni.2014.04.009.
-
(2014)
Immunity
, vol.40
, pp. 657-668
-
-
Falkowska, E.1
Le, K.M.2
Ramos, A.3
Doores, K.J.4
Lee, J.H.5
Blattner, C.6
Ramirez, A.7
Derking, R.8
van Gils, M.J.9
Liang, C.H.10
McBride, R.11
von Bredow, B.12
Shivatare, S.S.13
Wu, C.Y.14
Chan-Hui, P.Y.15
Liu, Y.16
Feizi, T.17
Zwick, M.B.18
Koff, W.C.19
Seaman, M.S.20
Swiderek, K.21
Moore, J.P.22
Evans, D.23
Paulson, J.C.24
Wong, C.H.25
Ward, A.B.26
Wilson, I.A.27
Sanders, R.W.28
Poignard, P.29
Burton, D.R.30
more..
-
30
-
-
84921607768
-
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
-
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Pena AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M. 2014. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature 515:138-142. http://dx.doi.org/10.1038/nature13601.
-
(2014)
Nature
, vol.515
, pp. 138-142
-
-
Huang, J.1
Kang, B.H.2
Pancera, M.3
Lee, J.H.4
Tong, T.5
Feng, Y.6
Imamichi, H.7
Georgiev, I.S.8
Chuang, G.Y.9
Druz, A.10
Doria-Rose, N.A.11
Laub, L.12
Sliepen, K.13
van Gils, M.J.14
de la Pena, A.T.15
Derking, R.16
Klasse, P.J.17
Migueles, S.A.18
Bailer, R.T.19
Alam, M.20
Pugach, P.21
Haynes, B.F.22
Wyatt, R.T.23
Sanders, R.W.24
Binley, J.M.25
Ward, A.B.26
Mascola, J.R.27
Kwong, P.D.28
Connors, M.29
more..
-
31
-
-
84899909771
-
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike
-
Scharf L, Scheid JF, Lee JH, West AP, Jr, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. 2014. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Rep 7:785-795. http://dx.doi.org/10.1016 /j.celrep.2014.04.001.
-
(2014)
Cell Rep
, vol.7
, pp. 785-795
-
-
Scharf, L.1
Scheid, J.F.2
Lee, J.H.3
West, A.P.4
Chen, C.5
Gao, H.6
Gnanapragasam, P.N.7
Mares, R.8
Seaman, M.S.9
Ward, A.B.10
Nussenzweig, M.C.11
Bjorkman, P.J.12
-
32
-
-
77952001983
-
Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization
-
Binley JM, Ban YE, Crooks ET, Eggink D, Osawa K, Schief WR, Sanders RW. 2010. Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization. J Virol 84:5637-5655. http://dx.doi.org/10.1128/JVI.00105-10.
-
(2010)
J Virol
, vol.84
, pp. 5637-5655
-
-
Binley, J.M.1
Ban, Y.E.2
Crooks, E.T.3
Eggink, D.4
Osawa, K.5
Schief, W.R.6
Sanders, R.W.7
-
33
-
-
84905386906
-
Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization
-
Kim AS, Leaman DP, Zwick MB. 2014. Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization. PLoS Pathog 10:e1004271. http://dx.doi.org/10.1371/journal.ppat.1004271.
-
(2014)
PLoS Pathog
, vol.10
-
-
Kim, A.S.1
Leaman, D.P.2
Zwick, M.B.3
-
34
-
-
0031749469
-
A role for carbohydrates in immune evasion in AIDS
-
Reitter JN, Means RE, Desrosiers RC. 1998. A role for carbohydrates in immune evasion in AIDS. Nat Med 4:679-684. http://dx.doi.org/10.1038 /nm0698-679.
-
(1998)
Nat Med
, vol.4
, pp. 679-684
-
-
Reitter, J.N.1
Means, R.E.2
Desrosiers, R.C.3
-
35
-
-
84869155712
-
Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape
-
Moore PL, Gray ES, Wibmer CK, Bhiman JN, Nonyane M, Sheward DJ, Hermanus T, Bajimaya S, Tumba NL, Abrahams MR, Lambson BE, Ranchobe N, Ping L, Ngandu N, Abdool Karim Q, Abdool Karim SS, Swanstrom RI, Seaman MS, Williamson C, Morris L. 2012. Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape. Nat Med 18:1688-1692. http://dx.doi.org/10.1038/nm.2985.
-
(2012)
Nat Med
, vol.18
, pp. 1688-1692
-
-
Moore, P.L.1
Gray, E.S.2
Wibmer, C.K.3
Bhiman, J.N.4
Nonyane, M.5
Sheward, D.J.6
Hermanus, T.7
Bajimaya, S.8
Tumba, N.L.9
Abrahams, M.R.10
Lambson, B.E.11
Ranchobe, N.12
Ping, L.13
Ngandu, N.14
Abdool Karim, Q.15
Abdool Karim, S.S.16
Swanstrom, R.I.17
Seaman, M.S.18
Williamson, C.19
Morris, L.20
more..
-
36
-
-
84905369598
-
Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
-
Gao F, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, Kelsoe G, Shaw GM, Hahn BH, Montefiori DC, Kamanga G, Cohen MS, Hraber P, Kwong PD, Korber BT, Mascola JR, Kepler TB, Haynes BF. 2014. Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies. Cell 158:481-491. http://dx.doi.org/10.1016/j.cell.2014.06.022.
-
(2014)
Cell
, vol.158
, pp. 481-491
-
-
Gao, F.1
Bonsignori, M.2
Liao, H.X.3
Kumar, A.4
Xia, S.M.5
Lu, X.6
Cai, F.7
Hwang, K.K.8
Song, H.9
Zhou, T.10
Lynch, R.M.11
Alam, S.M.12
Moody, M.A.13
Ferrari, G.14
Berrong, M.15
Kelsoe, G.16
Shaw, G.M.17
Hahn, B.H.18
Montefiori, D.C.19
Kamanga, G.20
Cohen, M.S.21
Hraber, P.22
Kwong, P.D.23
Korber, B.T.24
Mascola, J.R.25
Kepler, T.B.26
Haynes, B.F.27
more..
-
37
-
-
84887270287
-
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes
-
Wibmer CK, Bhiman JN, Gray ES, Tumba N, Abdool Karim SS, Williamson C, Morris L, Moore PL. 2013. Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes. PLoS Pathog 9:e1003738. http://dx.doi.org/10.1371/journal.ppat.1003738.
-
(2013)
PLoS Pathog
, vol.9
-
-
Wibmer, C.K.1
Bhiman, J.N.2
Gray, E.S.3
Tumba, N.4
Abdool Karim, S.S.5
Williamson, C.6
Morris, L.7
Moore, P.L.8
-
38
-
-
84878626061
-
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
-
McGuire AT, Hoot S, Dreyer AM, Lippy A, Stuart A, Cohen KW, Jardine J, Menis S, Scheid JF, West AP, Schief WR, Stamatatos L. 2013. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies. J Exp Med 210: 655-663. http://dx.doi.org/10.1084/jem.20122824.
-
(2013)
J Exp Med
, vol.210
, pp. 655-663
-
-
McGuire, A.T.1
Hoot, S.2
Dreyer, A.M.3
Lippy, A.4
Stuart, A.5
Cohen, K.W.6
Jardine, J.7
Menis, S.8
Scheid, J.F.9
West, A.P.10
Schief, W.R.11
Stamatatos, L.12
-
39
-
-
12144289425
-
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
-
Derdeyn CA, Decker JM, Bibollet-Ruche F, Mokili JL, Muldoon M, Denham SA, Heil ML, Kasolo F, Musonda R, Hahn BH, Shaw GM, Korber BT, Allen S, Hunter E. 2004. Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 303:2019-2022 http://dx.doi.org/10.1126/science.1093137.
-
(2004)
Science
, vol.303
, pp. 2019-2022
-
-
Derdeyn, C.A.1
Decker, J.M.2
Bibollet-Ruche, F.3
Mokili, J.L.4
Muldoon, M.5
Denham, S.A.6
Heil, M.L.7
Kasolo, F.8
Musonda, R.9
Hahn, B.H.10
Shaw, G.M.11
Korber, B.T.12
Allen, S.13
Hunter, E.14
-
40
-
-
18144397438
-
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viralRNA levels
-
Chohan B, Lang D, Sagar M, Korber B, Lavreys L, Richardson B, Overbaugh J. 2005. Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viralRNA levels. J Virol 79:6528-6531. http://dx.doi.org/10.1128/JVI.79.10.6528-6531.2005.
-
(2005)
J Virol
, vol.79
, pp. 6528-6531
-
-
Chohan, B.1
Lang, D.2
Sagar, M.3
Korber, B.4
Lavreys, L.5
Richardson, B.6
Overbaugh, J.7
-
41
-
-
82355180939
-
The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donor-recipient pair
-
Edo-Matas D, Rachinger A, Setiawan LC, Boeser-Nunnink BD, van 't Wout AB, Lemey P, Schuitemaker H. 2012. The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donor-recipient pair. Virology 422:70-80. http://dx.doi.org/10.1016/j.virol.2011.10.005.
-
(2012)
Virology
, vol.422
, pp. 70-80
-
-
Edo-Matas, D.1
Rachinger, A.2
Setiawan, L.C.3
Boeser-Nunnink, B.D.4
van 't Wout, A.B.5
Lemey, P.6
Schuitemaker, H.7
-
42
-
-
84876867850
-
Phenotypic properties of transmitted founder HIV-1
-
Parrish NF, Gao F, Li H, Giorgi EE, Barbian HJ, Parrish EH, Zajic L, Iyer SS, Decker JM, Kumar A, Hora B, Berg A, Cai F, Hopper J, Denny TN, Ding H, Ochsenbauer C, Kappes JC, Galimidi RP, West AP, Jr, Bjorkman PJ, Wilen CB, Doms RW, O'Brien M, Bhardwaj N, Borrow P, Haynes BF, Muldoon M, Theiler JP, Korber B, Shaw GM, Hahn BH. 2013. Phenotypic properties of transmitted founder HIV-1. Proc Natl Acad Sci U S A 110:6626-6633. http://dx.doi.org/10.1073 /pnas.1304288110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6626-6633
-
-
Parrish, N.F.1
Gao, F.2
Li, H.3
Giorgi, E.E.4
Barbian, H.J.5
Parrish, E.H.6
Zajic, L.7
Iyer, S.S.8
Decker, J.M.9
Kumar, A.10
Hora, B.11
Berg, A.12
Cai, F.13
Hopper, J.14
Denny, T.N.15
Ding, H.16
Ochsenbauer, C.17
Kappes, J.C.18
Galimidi, R.P.19
West, A.P.20
Bjorkman, P.J.21
Wilen, C.B.22
Doms, R.W.23
O'Brien, M.24
Bhardwaj, N.25
Borrow, P.26
Haynes, B.F.27
Muldoon, M.28
Theiler, J.P.29
Korber, B.30
Shaw, G.M.31
Hahn, B.H.32
more..
-
43
-
-
51749087085
-
Characteristics of HIV type 1 (HIV-1) glycoprotein 120 env sequences in motherinfant pairs infected with HIV-1 subtype CRF01_AE
-
Samleerat T, Braibant M, Jourdain G, Moreau A, Ngo-Giang-Huong N, Leechanachai P, Hemvuttiphan J, Hinjiranandana T, Changchit T, Warachit B, Suraseranivong V, Lallemant M, Barin F. 2008. Characteristics of HIV type 1 (HIV-1) glycoprotein 120 env sequences in motherinfant pairs infected with HIV-1 subtype CRF01_AE. J Infect Dis 198:868-876 http://dx.doi.org/10.1086/591251.
-
(2008)
J Infect Dis
, vol.198
, pp. 868-876
-
-
Samleerat, T.1
Braibant, M.2
Jourdain, G.3
Moreau, A.4
Ngo-Giang-Huong, N.5
Leechanachai, P.6
Hemvuttiphan, J.7
Hinjiranandana, T.8
Changchit, T.9
Warachit, B.10
Suraseranivong, V.11
Lallemant, M.12
Barin, F.13
-
44
-
-
78651237643
-
HIV-1 envelope subregion length variation during disease progression
-
Curlin ME, Zioni R, Hawes SE, Liu Y, Deng W, Gottlieb GS, Zhu T, Mullins JI. 2010. HIV-1 envelope subregion length variation during disease progression. PLoS Pathog 6:e1001228. http://dx.doi.org/10.1371 /journal.ppat.1001228.
-
(2010)
PLoS Pathog
, vol.6
-
-
Curlin, M.E.1
Zioni, R.2
Hawes, S.E.3
Liu, Y.4
Deng, W.5
Gottlieb, G.S.6
Zhu, T.7
Mullins, J.I.8
-
45
-
-
49149118421
-
Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection
-
Bunnik EM, Pisas L, van Nuenen AC, Schuitemaker H. 2008. Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection. J Virol 82:7932-7941. http://dx.doi.org/10.1128/JVI.00757-08.
-
(2008)
J Virol
, vol.82
, pp. 7932-7941
-
-
Bunnik, E.M.1
Pisas, L.2
van Nuenen, A.C.3
Schuitemaker, H.4
-
46
-
-
0030842609
-
Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies
-
Chackerian B, Rudensey LM, Overbaugh J. 1997. Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies. J Virol 71:7719-7727.
-
(1997)
J Virol
, vol.71
, pp. 7719-7727
-
-
Chackerian, B.1
Rudensey, L.M.2
Overbaugh, J.3
-
47
-
-
0028244285
-
An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization
-
Back NK, Smit L, De Jong JJ, Keulen W, Schutten M, Goudsmit J, Tersmette M. 1994. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 199:431-438 http://dx.doi.org/10.1006/viro.1994.1141.
-
(1994)
Virology
, vol.199
, pp. 431-438
-
-
Back, N.K.1
Smit, L.2
De Jong, J.J.3
Keulen, W.4
Schutten, M.5
Goudsmit, J.6
Tersmette, M.7
-
48
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
-
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O'Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR. 2014. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature 509:55-62. http://dx.doi.org/10.1038/nature13036.
-
(2014)
Nature
, vol.509
, pp. 55-62
-
-
Doria-Rose, N.A.1
Schramm, C.A.2
Gorman, J.3
Moore, P.L.4
Bhiman, J.N.5
DeKosky, B.J.6
Ernandes, M.J.7
Georgiev, I.S.8
Kim, H.J.9
Pancera, M.10
Staupe, R.P.11
Altae-Tran, H.R.12
Bailer, R.T.13
Crooks, E.T.14
Cupo, A.15
Druz, A.16
Garrett, N.J.17
Hoi, K.H.18
Kong, R.19
Louder, M.K.20
Longo, N.S.21
McKee, K.22
Nonyane, M.23
O'Dell, S.24
Roark, R.S.25
Rudicell, R.S.26
Schmidt, S.D.27
Sheward, D.J.28
Soto, C.29
Wibmer, C.K.30
Yang, Y.31
Zhang, Z.32
Mullikin, J.C.33
Binley, J.M.34
Sanders, R.W.35
Wilson, I.A.36
Moore, J.P.37
Ward, A.B.38
Georgiou, G.39
Williamson, C.40
Abdool Karim, S.S.41
Morris, L.42
Kwong, P.D.43
Shapiro, L.44
Mascola, J.R.45
more..
-
49
-
-
84876333290
-
Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies
-
Moore PL, Sheward D, Nonyane M, Ranchobe N, Hermanus T, Gray ES, Abdool Karim SS, Williamson C, Morris L. 2013. Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies. J Virol 87:4882-4894. http://dx.doi.org/10.1128/JVI.03424-12.
-
(2013)
J Virol
, vol.87
, pp. 4882-4894
-
-
Moore, P.L.1
Sheward, D.2
Nonyane, M.3
Ranchobe, N.4
Hermanus, T.5
Gray, E.S.6
Abdool Karim, S.S.7
Williamson, C.8
Morris, L.9
-
50
-
-
33745912405
-
A time-and cost-efficient system for high-level protein production in mammalian cells
-
Aricescu AR, Lu W, Jones EY. 2006. A time-and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallogr D Biol Crystallogr 62:1243-1250. http://dx.doi.org/10.1107/S0907444906029799.
-
(2006)
Acta Crystallogr D Biol Crystallogr
, vol.62
, pp. 1243-1250
-
-
Aricescu, A.R.1
Lu, W.2
Jones, E.Y.3
-
51
-
-
77956366187
-
Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans
-
Dunlop DC, Bonomelli C, Mansab F, Vasiljevic S, Doores KJ, Wormald MR, Palma AS, Feizi T, Harvey DJ, Dwek RA, Crispin M, Scanlan CN. 2010 Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans. Glycobiology 20:812-823. http://dx.doi.org/10.1093/glycob/cwq020.
-
(2010)
Glycobiology
, vol.20
, pp. 812-823
-
-
Dunlop, D.C.1
Bonomelli, C.2
Mansab, F.3
Vasiljevic, S.4
Doores, K.J.5
Wormald, M.R.6
Palma, A.S.7
Feizi, T.8
Harvey, D.J.9
Dwek, R.A.10
Crispin, M.11
Scanlan, C.N.12
-
52
-
-
34447310112
-
Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions
-
Royle L, Radcliffe CM, Dwek RA, Rudd PM. 2006. Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions. Methods Mol Biol 347:125-143.
-
(2006)
Methods Mol Biol
, vol.347
, pp. 125-143
-
-
Royle, L.1
Radcliffe, C.M.2
Dwek, R.A.3
Rudd, P.M.4
-
53
-
-
61849129614
-
Development of a single col-umn method for the separation of lipid-and protein-derived oligosaccharides
-
Neville DC, Dwek RA, Butters TD. 2009. Development of a single col-umn method for the separation of lipid-and protein-derived oligosaccharides. J Proteome Res 8:681-687. http://dx.doi.org/10.1021/pr800704t.
-
(2009)
J Proteome Res
, vol.8
, pp. 681-687
-
-
Neville, D.C.1
Dwek, R.A.2
Butters, T.D.3
-
54
-
-
23244434512
-
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
-
Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, Koutsoukos M, Voss G, Goepfert P, Gilbert P, Greene KM, Bilska M, Kothe DL, Salazar-Gonzalez JF, Wei X, Decker JM, Hahn BH, Montefiori DC. 2005 Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol 79:10108-10125. http://dx.doi.org/10.1128/JVI.79.16.10108-10125.2005.
-
(2005)
J Virol
, vol.79
, pp. 10108-10125
-
-
Li, M.1
Gao, F.2
Mascola, J.R.3
Stamatatos, L.4
Polonis, V.R.5
Koutsoukos, M.6
Voss, G.7
Goepfert, P.8
Gilbert, P.9
Greene, K.M.10
Bilska, M.11
Kothe, D.L.12
Salazar-Gonzalez, J.F.13
Wei, X.14
Decker, J.M.15
Hahn, B.H.16
Montefiori, D.C.17
-
55
-
-
45849125030
-
Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays
-
Unit 12.11
-
Montefiori DC. 2005. Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays. Curr Protoc Immunol Chapter 12:Unit 12.11.
-
(2005)
Curr Protoc Immunol Chapter
, vol.12
-
-
Montefiori, D.C.1
-
56
-
-
38849090714
-
The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection
-
Moore PL, Gray ES, Choge IA, Ranchobe N, Mlisana K, Abdool Karim SS, Williamson C, Morris L, Team CS. 2008. The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection. J Virol 82:1860-1869. http://dx.doi.org /10.1128/JVI.02187-07.
-
(2008)
J Virol
, vol.82
, pp. 1860-1869
-
-
Moore, P.L.1
Gray, E.S.2
Choge, I.A.3
Ranchobe, N.4
Mlisana, K.5
Abdool Karim, S.S.6
Williamson, C.7
Morris, L.8
Team, C.S.9
-
57
-
-
84946576244
-
Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
-
Bhiman JN, Anthony C, Doria-Rose NA, Karimanzira O, Schramm CA, Khoza T, Kitchin D, Botha G, Gorman J, Garrett NJ, Abdool Karim SS, Shapiro L, Williamson C, Kwong PD, Mascola JR, Morris L, Moore PL. 2015 Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies. Nat Med 21:1332-1336. http://dx.doi.org/10.1038/nm.3963.
-
(2015)
Nat Med
, vol.21
, pp. 1332-1336
-
-
Bhiman, J.N.1
Anthony, C.2
Doria-Rose, N.A.3
Karimanzira, O.4
Schramm, C.A.5
Khoza, T.6
Kitchin, D.7
Botha, G.8
Gorman, J.9
Garrett, N.J.10
Abdool Karim, S.S.11
Shapiro, L.12
Williamson, C.13
Kwong, P.D.14
Mascola, J.R.15
Morris, L.16
Moore, P.L.17
-
58
-
-
84890858459
-
Crystal structure of a soluble cleaved HIV-1 envelope trimer
-
Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA. 2013. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science 342: 1477-1483. http://dx.doi.org/10.1126/science.1245625.
-
(2013)
Science
, vol.342
, pp. 1477-1483
-
-
Julien, J.P.1
Cupo, A.2
Sok, D.3
Stanfield, R.L.4
Lyumkis, D.5
Deller, M.C.6
Klasse, P.J.7
Burton, D.R.8
Sanders, R.W.9
Moore, J.P.10
Ward, A.B.11
Wilson, I.A.12
-
59
-
-
84875034460
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
-
Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. 2013. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc Natl Acad SciUSA110:4351-4356 http://dx.doi.org/10.1073/pnas.1217537110.
-
(2013)
Proc Natl Acad SciUSA
, vol.110
, pp. 4351-4356
-
-
Julien, J.P.1
Lee, J.H.2
Cupo, A.3
Murin, C.D.4
Derking, R.5
Hoffenberg, S.6
Caulfield, M.J.7
King, C.R.8
Marozsan, A.J.9
Klasse, P.J.10
Sanders, R.W.11
Moore, J.P.12
Wilson, I.A.13
Ward, A.B.14
-
60
-
-
79961184231
-
Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry
-
Go EP, Hewawasam G, Liao HX, Chen H, Ping LH, Anderson JA, Hua DC, Haynes BF, Desaire H. 2011. Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry. J Virol 85:8270-8284. http://dx.doi.org/10.1128/JVI.05053-11.
-
(2011)
J Virol
, vol.85
, pp. 8270-8284
-
-
Go, E.P.1
Hewawasam, G.2
Liao, H.X.3
Chen, H.4
Ping, L.H.5
Anderson, J.A.6
Hua, D.C.7
Haynes, B.F.8
Desaire, H.9
-
61
-
-
84909640954
-
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
-
Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, Tumba N, Yang Y, Zhang B, Cohen MS, Haynes BF, Mascola JR, Morris L, Munro JB, Blanchard SC, Mothes W, Connors M, Kwong PD. 2014. Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature 514:455-461. http://dx.doi.org/10.1038/nature13808.
-
(2014)
Nature
, vol.514
, pp. 455-461
-
-
Pancera, M.1
Zhou, T.2
Druz, A.3
Georgiev, I.S.4
Soto, C.5
Gorman, J.6
Huang, J.7
Acharya, P.8
Chuang, G.Y.9
Ofek, G.10
Stewart-Jones, G.B.11
Stuckey, J.12
Bailer, R.T.13
Joyce, M.G.14
Louder, M.K.15
Tumba, N.16
Yang, Y.17
Zhang, B.18
Cohen, M.S.19
Haynes, B.F.20
Mascola, J.R.21
Morris, L.22
Munro, J.B.23
Blanchard, S.C.24
Mothes, W.25
Connors, M.26
Kwong, P.D.27
more..
-
62
-
-
34648816125
-
N-linked glycan modifications in gp120 of human immunodeficiency virus type 1 subtype C render partial sensitivity to 2G12 antibody neutralization
-
Gray ES, Moore PL, Pantophlet RA, Morris L. 2007. N-linked glycan modifications in gp120 of human immunodeficiency virus type 1 subtype C render partial sensitivity to 2G12 antibody neutralization. J Virol 81: 10769-10776. http://dx.doi.org/10.1128/JVI.01106-07.
-
(2007)
J Virol
, vol.81
, pp. 10769-10776
-
-
Gray, E.S.1
Moore, P.L.2
Pantophlet, R.A.3
Morris, L.4
-
63
-
-
0036637385
-
The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120
-
Sanders RW, Venturi M, Schiffner L, Kalyanaraman R, Katinger H, Lloyd KO, Kwong PD, Moore JP. 2002. The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120. J Virol 76:7293-7305. http://dx.doi.org/10.1128/JVI.76.14.7293-7305.2002.
-
(2002)
J Virol
, vol.76
, pp. 7293-7305
-
-
Sanders, R.W.1
Venturi, M.2
Schiffner, L.3
Kalyanaraman, R.4
Katinger, H.5
Lloyd, K.O.6
Kwong, P.D.7
Moore, J.P.8
-
64
-
-
84930891393
-
Glycan microheterogeneity at the PGT135 antibody recognition site on HIV-1 gp120 reveals a molecular mechanism for neutralization resistance
-
Pritchard LK, Spencer DI, Royle L, Vasiljevic S, Krumm SA, Doores KJ, Crispin M. 2015. Glycan microheterogeneity at the PGT135 antibody recognition site on HIV-1 gp120 reveals a molecular mechanism for neutralization resistance. J Virol 89:6952-6959. http://dx.doi.org/10.1128 /JVI.00230-15.
-
(2015)
J Virol
, vol.89
, pp. 6952-6959
-
-
Pritchard, L.K.1
Spencer, D.I.2
Royle, L.3
Vasiljevic, S.4
Krumm, S.A.5
Doores, K.J.6
Crispin, M.7
-
65
-
-
0034598905
-
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
-
Geijtenbeek TB, Kwon DS, Torensma R, van Vliet SJ, van Duijnhoven GC, Middel J, Cornelissen IL, Nottet HS, KewalRamani VN, Littman DR, Figdor CG, van Kooyk Y. 2000. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100: 587-597. http://dx.doi.org/10.1016/S0092-8674(00)80694-7.
-
(2000)
Cell
, vol.100
, pp. 587-597
-
-
Geijtenbeek, T.B.1
Kwon, D.S.2
Torensma, R.3
van Vliet, S.J.4
van Duijnhoven, G.C.5
Middel, J.6
Cornelissen, I.L.7
Nottet, H.S.8
KewalRamani, V.N.9
Littman, D.R.10
Figdor, C.G.11
van Kooyk, Y.12
-
66
-
-
0036892624
-
Human immunodeficiency virus envelope (gp120) binding to DCSIGN and primary dendritic cells is carbohydrate dependent but does not involve 2G12 or cyanovirin binding sites: implications for structural analyses of gp120-DC-SIGN binding
-
Hong PW, Flummerfelt KB, de Parseval A, Gurney K, Elder JH, Lee B. 2002 Human immunodeficiency virus envelope (gp120) binding to DCSIGN and primary dendritic cells is carbohydrate dependent but does not involve 2G12 or cyanovirin binding sites: implications for structural analyses of gp120-DC-SIGN binding. J Virol 76:12855-12865. http://dx.doi.org/10.1128/JVI.76.24.12855-12865.2002.
-
(2002)
J Virol
, vol.76
, pp. 12855-12865
-
-
Hong, P.W.1
Flummerfelt, K.B.2
de Parseval, A.3
Gurney, K.4
Elder, J.H.5
Lee, B.6
-
67
-
-
0036172314
-
DC-SIGN-mediated internalization of HIV is required for transenhancement of T cell infection
-
Kwon DS, Gregorio G, Bitton N, Hendrickson WA, Littman DR. 2002. DC-SIGN-mediated internalization of HIV is required for transenhancement of T cell infection. Immunity 16:135-144. http://dx.doi.org /10.1016/S1074-7613(02)00259-5.
-
(2002)
Immunity
, vol.16
, pp. 135-144
-
-
Kwon, D.S.1
Gregorio, G.2
Bitton, N.3
Hendrickson, W.A.4
Littman, D.R.5
-
68
-
-
84911475851
-
HIV-1 envelope glycan moieties modulate HIV-1 transmission
-
Shen R, Raska M, Bimczok D, Novak J, Smith PD. 2014. HIV-1 envelope glycan moieties modulate HIV-1 transmission. J Virol 88:14258-14267. http://dx.doi.org/10.1128/JVI.02164-14.
-
(2014)
J Virol
, vol.88
, pp. 14258-14267
-
-
Shen, R.1
Raska, M.2
Bimczok, D.3
Novak, J.4
Smith, P.D.5
-
69
-
-
67349176314
-
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo
-
Banerjee K, Andjelic S, Klasse PJ, Kang Y, Sanders RW, Michael E, Durso RJ, Ketas TJ, Olson WC, Moore JP. 2009. Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo. Virology 389:108-121. http://dx.doi.org/10.1016/j.virol.2009.04.001.
-
(2009)
Virology
, vol.389
, pp. 108-121
-
-
Banerjee, K.1
Andjelic, S.2
Klasse, P.J.3
Kang, Y.4
Sanders, R.W.5
Michael, E.6
Durso, R.J.7
Ketas, T.J.8
Olson, W.C.9
Moore, J.P.10
-
70
-
-
84863393535
-
Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice
-
Banerjee K, Michael E, Eggink D, van Montfort T, Lasnik AB, Palmer KE, Sanders RW, Moore JP, Klasse PJ. 2012. Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice. AIDS ResHum Retroviruses 28:206-214. http://dx.doi.org/10.1089/aid.2011.0101.
-
(2012)
AIDS ResHum Retroviruses
, vol.28
, pp. 206-214
-
-
Banerjee, K.1
Michael, E.2
Eggink, D.3
van Montfort, T.4
Lasnik, A.B.5
Palmer, K.E.6
Sanders, R.W.7
Moore, J.P.8
Klasse, P.J.9
-
71
-
-
77957271989
-
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity
-
Kong L, Sheppard NC, Stewart-Jones GB, Robson CL, Chen H, Xu X, Krashias G, Bonomelli C, Scanlan CN, Kwong PD, Jeffs SA, Jones IM, Sattentau QJ. 2010. Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity. J Mol Biol 403: 131-147. http://dx.doi.org/10.1016/j.jmb.2010.08.033.
-
(2010)
J Mol Biol
, vol.403
, pp. 131-147
-
-
Kong, L.1
Sheppard, N.C.2
Stewart-Jones, G.B.3
Robson, C.L.4
Chen, H.5
Xu, X.6
Krashias, G.7
Bonomelli, C.8
Scanlan, C.N.9
Kwong, P.D.10
Jeffs, S.A.11
Jones, I.M.12
Sattentau, Q.J.13
-
72
-
-
84943588030
-
Model building and refinement of a natively glycosylated HIV-1 Env protein by highresolution cryoelectron microscopy
-
Lee JH, de Val N, Lyumkis D, Ward AB. 2015. Model building and refinement of a natively glycosylated HIV-1 Env protein by highresolution cryoelectron microscopy. Structure 23:1943-1951. http://dx.doi.org/10.1016/j.str.2015.07.020.
-
(2015)
Structure
, vol.23
, pp. 1943-1951
-
-
Lee, J.H.1
de Val, N.2
Lyumkis, D.3
Ward, A.B.4
|