메뉴 건너뛰기




Volumn 22, Issue 1, 2017, Pages 158-168

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer

Author keywords

Cardamonin; Prostate cancer; SH2 domain; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; CARDAMONIN; DNA; STAT3 PROTEIN; UNCLASSIFIED DRUG; CHALCONE DERIVATIVE; STAT3 PROTEIN, HUMAN;

EID: 85000634171     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-016-1313-7     Document Type: Article
Times cited : (70)

References (36)
  • 1
    • 84923007306 scopus 로고    scopus 로고
    • Evaluation of environmental risk factors for prostate cancer in a population of Iranian patients
    • PID: 25605146
    • Pouresmaeili F, Hosseini SJ, Farzaneh F et al (2014) Evaluation of environmental risk factors for prostate cancer in a population of Iranian patients. Asian Pac J Cancer Prev 15:10603–10605
    • (2014) Asian Pac J Cancer Prev , vol.15 , pp. 10603-10605
    • Pouresmaeili, F.1    Hosseini, S.J.2    Farzaneh, F.3
  • 2
    • 77952878196 scopus 로고    scopus 로고
    • Defining and treating high-risk prostate cancer: can we do better?
    • PID: 20363552
    • Gerber L, Banez LL, Freedland SJ (2010) Defining and treating high-risk prostate cancer: can we do better? Eur Urol 58:8–9
    • (2010) Eur Urol , vol.58 , pp. 8-9
    • Gerber, L.1    Banez, L.L.2    Freedland, S.J.3
  • 3
    • 22144484150 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer
    • COI: 1:CAS:528:DC%2BD2MXmtlSlt7g%3D, PID: 16014598
    • Sharifi N, Gulley JL, Dahut WL (2005) Androgen deprivation therapy for prostate cancer. Jama 294:238–244
    • (2005) Jama , vol.294 , pp. 238-244
    • Sharifi, N.1    Gulley, J.L.2    Dahut, W.L.3
  • 4
    • 84905089818 scopus 로고    scopus 로고
    • Metastatic castration-resistant prostate cancer (CRPC): preclinical and clinical evidence for the sequential use of novel therapeutics
    • COI: 1:CAS:528:DC%2BC2cXht1KisL%2FL, PID: 24452758
    • Mukherji D, Omlin A, Pezaro C, Shamseddine A, de Bono J (2014) Metastatic castration-resistant prostate cancer (CRPC): preclinical and clinical evidence for the sequential use of novel therapeutics. Cancer Metastasis Rev 33:555–566
    • (2014) Cancer Metastasis Rev , vol.33 , pp. 555-566
    • Mukherji, D.1    Omlin, A.2    Pezaro, C.3    Shamseddine, A.4    de Bono, J.5
  • 5
    • 84885926441 scopus 로고    scopus 로고
    • Novel therapeutic approaches for the treatment of castration-resistant prostate cancer
    • COI: 1:CAS:528:DC%2BC3sXhsleqsLzF, PID: 23792785
    • Heidegger I, Massoner P, Eder IE et al (2013) Novel therapeutic approaches for the treatment of castration-resistant prostate cancer. J Steroid Biochem Mol Biol 138:248–256
    • (2013) J Steroid Biochem Mol Biol , vol.138 , pp. 248-256
    • Heidegger, I.1    Massoner, P.2    Eder, I.E.3
  • 6
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer–new molecular targets come of age
    • COI: 1:CAS:528:DC%2BD2cXhtlaqtb0%3D
    • Yu H, Jove R (2004) The STATs of cancer–new molecular targets come of age. Nature Rev Cancer 4:97–105
    • (2004) Nature Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 7
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • COI: 1:CAS:528:DC%2BD3MXktVSjsr0%3D, PID: 11357143
    • Blume-Jensen P, Hunter T (2001) Oncogenic kinase signalling. Nature 411:355–365
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 8
    • 0038673854 scopus 로고    scopus 로고
    • StAT signaling in cancer: insights into pathogenesis and treatment strategies
    • COI: 1:CAS:528:DC%2BD3sXnt12gsLw%3D, PID: 12613201
    • Frank DA (2003) StAT signaling in cancer: insights into pathogenesis and treatment strategies. Cancer Treat Res 115:267–291
    • (2003) Cancer Treat Res , vol.115 , pp. 267-291
    • Frank, D.A.1
  • 9
    • 84868693885 scopus 로고    scopus 로고
    • Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38XhvVKqu73O, PID: 23103770
    • Subramaniam A, Shanmugam MK, Perumal E et al (2013) Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma. Biochim Biophys Acta 1835:46–60
    • (2013) Biochim Biophys Acta , vol.1835 , pp. 46-60
    • Subramaniam, A.1    Shanmugam, M.K.2    Perumal, E.3
  • 10
    • 84893429662 scopus 로고    scopus 로고
    • Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors
    • COI: 1:CAS:528:DC%2BC2cXmt1agu7Y%3D, PID: 24388873
    • Siveen KS, Sikka S, Surana R et al (2014) Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors. Biochim Biophys Acta 1845:136–154
    • (2014) Biochim Biophys Acta , vol.1845 , pp. 136-154
    • Siveen, K.S.1    Sikka, S.2    Surana, R.3
  • 11
    • 84957612113 scopus 로고    scopus 로고
    • Targeting transcription factor STAT3 for cancer prevention and therapy
    • Chai EZ, Shanmugam MK, Arfuso F et al (2015) Targeting transcription factor STAT3 for cancer prevention and therapy. Pharmacol Ther. doi:10.1016/j.pharmthera.2015.10.004
    • (2015) Pharmacol Ther
    • Chai, E.Z.1    Shanmugam, M.K.2    Arfuso, F.3
  • 12
    • 0017143525 scopus 로고
    • Cardamonin and alpinetin from the seeds of Amomum subulatum
    • COI: 1:STN:280:DyaE283mvF2qsA%3D%3D, PID: 959382
    • Bheemasankara Rao C, Namosiva Rao T, Suryaprakasam S (1976) Cardamonin and alpinetin from the seeds of Amomum subulatum. Planta Med 29:391–392
    • (1976) Planta Med , vol.29 , pp. 391-392
    • Bheemasankara Rao, C.1    Namosiva Rao, T.2    Suryaprakasam, S.3
  • 13
    • 84862811331 scopus 로고    scopus 로고
    • Cardamonin from Alpinia rafflesiana inhibits inflammatory responses in IFN-gamma/LPS-stimulated BV2 microglia via NF-kappaB signalling pathway
    • COI: 1:CAS:528:DC%2BC38Xit12ht7o%3D, PID: 22306767
    • Chow YL, Lee KH, Vidyadaran S et al (2012) Cardamonin from Alpinia rafflesiana inhibits inflammatory responses in IFN-gamma/LPS-stimulated BV2 microglia via NF-kappaB signalling pathway. Int Immunopharmacol 12:657–665
    • (2012) Int Immunopharmacol , vol.12 , pp. 657-665
    • Chow, Y.L.1    Lee, K.H.2    Vidyadaran, S.3
  • 14
    • 33748490486 scopus 로고    scopus 로고
    • The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages
    • COI: 1:CAS:528:DC%2BD28XptlSlsbY%3D, PID: 16894344
    • Hatziieremia S, Gray AI, Ferro VA, Paul A, Plevin R (2006) The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages. Br J Pharmacol 149:188–198
    • (2006) Br J Pharmacol , vol.149 , pp. 188-198
    • Hatziieremia, S.1    Gray, A.I.2    Ferro, V.A.3    Paul, A.4    Plevin, R.5
  • 15
    • 29244443231 scopus 로고    scopus 로고
    • Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera
    • COI: 1:CAS:528:DC%2BD28XhslCjsQ%3D%3D, PID: 16183703
    • Lee JH, Jung HS, Giang PM et al (2006) Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera. J Pharmacol Exp Ther 316:271–278
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 271-278
    • Lee, J.H.1    Jung, H.S.2    Giang, P.M.3
  • 16
    • 80052960367 scopus 로고    scopus 로고
    • Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis
    • COI: 1:CAS:528:DC%2BC3MXhtF2qsrjN, PID: 21802698
    • Bajgai SP, Prachyawarakorn V, Mahidol C, Ruchirawat S, Kittakoop P (2011) Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis. Phytochemistry 72:2062–2067
    • (2011) Phytochemistry , vol.72 , pp. 2062-2067
    • Bajgai, S.P.1    Prachyawarakorn, V.2    Mahidol, C.3    Ruchirawat, S.4    Kittakoop, P.5
  • 17
    • 36148998010 scopus 로고    scopus 로고
    • Cytotoxic chalcones and antioxidants from the fruits of a Syzygium samarangense (Wax Jambu)
    • COI: 1:CAS:528:DC%2BD2sXhtlCntLfO, PID: 22359426
    • Simirgiotis MJ, Adachi S, To S et al (2008) Cytotoxic chalcones and antioxidants from the fruits of a Syzygium samarangense (Wax Jambu). Food Chem 107:813–819
    • (2008) Food Chem , vol.107 , pp. 813-819
    • Simirgiotis, M.J.1    Adachi, S.2    To, S.3
  • 18
    • 76749118898 scopus 로고    scopus 로고
    • Cardamonin is a bifunctional vasodilator that inhibits Ca(v)1.2 current and stimulates K(Ca)1.1 current in rat tail artery myocytes
    • COI: 1:CAS:528:DC%2BC3cXltVCkt74%3D, PID: 19923439
    • Fusi F, Cavalli M, Mulholland D et al (2010) Cardamonin is a bifunctional vasodilator that inhibits Ca(v)1.2 current and stimulates K(Ca)1.1 current in rat tail artery myocytes. J Pharmacol Exp Ther 332:531–540
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 531-540
    • Fusi, F.1    Cavalli, M.2    Mulholland, D.3
  • 19
    • 80051684818 scopus 로고    scopus 로고
    • Cardamonin stimulates glucose uptake through translocation of glucose transporter-4 in L6 myotubes
    • COI: 1:CAS:528:DC%2BC3MXptlyqtbk%3D, PID: 21305634
    • Yamamoto N, Kawabata K, Sawada K et al (2011) Cardamonin stimulates glucose uptake through translocation of glucose transporter-4 in L6 myotubes. Phytother Res 25:1218–1224
    • (2011) Phytother Res , vol.25 , pp. 1218-1224
    • Yamamoto, N.1    Kawabata, K.2    Sawada, K.3
  • 20
    • 84930673499 scopus 로고    scopus 로고
    • Cardamonin inhibits metastasis of lewis lung carcinoma cells by decreasing mTOR activity
    • PID: 25996501
    • Niu PG, Zhang YX, Shi DH, Liu Y, Chen YY, Deng J (2015) Cardamonin inhibits metastasis of lewis lung carcinoma cells by decreasing mTOR activity. PloS One 10:e0127778
    • (2015) PloS One , vol.10
    • Niu, P.G.1    Zhang, Y.X.2    Shi, D.H.3    Liu, Y.4    Chen, Y.Y.5    Deng, J.6
  • 21
    • 84857236804 scopus 로고    scopus 로고
    • Cardamonin exerts potent activity against multiple myeloma through blockade of NF-kappaB pathway in vitro
    • COI: 1:CAS:528:DC%2BC38XivVOrt7g%3D, PID: 22226224
    • Qin Y, Sun CY, Lu FR et al (2012) Cardamonin exerts potent activity against multiple myeloma through blockade of NF-kappaB pathway in vitro. Leuk Res 36:514–520
    • (2012) Leuk Res , vol.36 , pp. 514-520
    • Qin, Y.1    Sun, C.Y.2    Lu, F.R.3
  • 22
    • 84878869508 scopus 로고    scopus 로고
    • Cardamonin suppresses the proliferation of colon cancer cells by promoting beta-catenin degradation
    • COI: 1:CAS:528:DC%2BC3sXhtlWlt7bI, PID: 23538439
    • Park S, Gwak J, Han SJ, Oh S (2013) Cardamonin suppresses the proliferation of colon cancer cells by promoting beta-catenin degradation. Biol Pharm Bull 36:1040–1044
    • (2013) Biol Pharm Bull , vol.36 , pp. 1040-1044
    • Park, S.1    Gwak, J.2    Han, S.J.3    Oh, S.4
  • 23
    • 84894640317 scopus 로고    scopus 로고
    • Antiproliferative activity and induction of apoptosis in PC-3 cells by the chalcone cardamonin from Campomanesia adamantium (Myrtaceae) in a bioactivity-guided study
    • PID: 24514747
    • Pascoal AC, Ehrenfried CA, Lopez BG et al (2014) Antiproliferative activity and induction of apoptosis in PC-3 cells by the chalcone cardamonin from Campomanesia adamantium (Myrtaceae) in a bioactivity-guided study. Molecules 19:1843–1855
    • (2014) Molecules , vol.19 , pp. 1843-1855
    • Pascoal, A.C.1    Ehrenfried, C.A.2    Lopez, B.G.3
  • 24
    • 79960897861 scopus 로고    scopus 로고
    • Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model
    • COI: 1:CAS:528:DC%2BC3MXpt1yhsro%3D, PID: 21480220
    • Shanmugam MK, Manu KA, Ong TH et al (2011) Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model. Int J Cancer 129:1552–1563
    • (2011) Int J Cancer , vol.129 , pp. 1552-1563
    • Shanmugam, M.K.1    Manu, K.A.2    Ong, T.H.3
  • 25
    • 0032499801 scopus 로고    scopus 로고
    • Three-dimensional structure of the Stat3beta homodimer bound to DNA
    • COI: 1:CAS:528:DyaK1cXksFynsr4%3D, PID: 9671298
    • Becker S, Groner B, Muller CW (1998) Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature 394:145–151
    • (1998) Nature , vol.394 , pp. 145-151
    • Becker, S.1    Groner, B.2    Muller, C.W.3
  • 26
    • 84910007055 scopus 로고    scopus 로고
    • Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells
    • COI: 1:CAS:528:DC%2BC2cXhsVaku7fM, PID: 25130169
    • Kim SM, Lee JH, Sethi G et al (2014) Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells. Cancer Lett 354:153–163
    • (2014) Cancer Lett , vol.354 , pp. 153-163
    • Kim, S.M.1    Lee, J.H.2    Sethi, G.3
  • 27
    • 84873908235 scopus 로고    scopus 로고
    • Potential use of STAT3 inhibitors in targeted prostate cancer therapy: future prospects
    • Shodeinde AL, Barton BE (2012) Potential use of STAT3 inhibitors in targeted prostate cancer therapy: future prospects. Oncotargets Ther 5:119–125
    • (2012) Oncotargets Ther , vol.5 , pp. 119-125
    • Shodeinde, A.L.1    Barton, B.E.2
  • 28
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: novel molecular targets for cancer drug discovery
    • COI: 1:CAS:528:DC%2BD3MXhsF2rsro%3D, PID: 11426647
    • Turkson J, Jove R (2000) STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 19:6613–6626
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 29
    • 32144453842 scopus 로고    scopus 로고
    • JAK/STAT signal transduction: regulators and implication in hematological malignancies
    • COI: 1:CAS:528:DC%2BD28XhtlKmt70%3D, PID: 16426581
    • Valentino L, Pierre J (2006) JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 71:713–721
    • (2006) Biochem Pharmacol , vol.71 , pp. 713-721
    • Valentino, L.1    Pierre, J.2
  • 30
    • 16344380754 scopus 로고    scopus 로고
    • A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
    • COI: 1:CAS:528:DC%2BD2MXjt1Oiu78%3D, PID: 15781862
    • Song H, Wang R, Wang S, Lin J (2005) A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci USA 102:4700–4705
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4700-4705
    • Song, H.1    Wang, R.2    Wang, S.3    Lin, J.4
  • 31
    • 84952874601 scopus 로고    scopus 로고
    • ) Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells
    • Wu N, Liu J, Zhao X et al (2015) Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells. Tumour Biol. doi:10.1007/s13277-015-3673-y
    • (2015) Tumour Biol
    • Wu, N.1    Liu, J.2    Zhao, X.3
  • 32
    • 85009494895 scopus 로고    scopus 로고
    • Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo
    • Jia D, Tan Y, Liu H et al. (2015) Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget
    • (2015) Oncotarget
    • Jia, D.1    Tan, Y.2    Liu, H.3
  • 33
    • 33947574564 scopus 로고    scopus 로고
    • Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution
    • COI: 1:CAS:528:DC%2BD2sXjsFShu7g%3D, PID: 17341611
    • Aggarwal BB, Sethi G, Ahn KS et al (2006) Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann N Y Acad Sci 1091:151–169
    • (2006) Ann N Y Acad Sci , vol.1091 , pp. 151-169
    • Aggarwal, B.B.1    Sethi, G.2    Ahn, K.S.3
  • 34
    • 80052197203 scopus 로고    scopus 로고
    • Small molecule inhibitors of STAT3 for cancer therapy
    • COI: 1:CAS:528:DC%2BC3MXht1KjsbrJ, PID: 21824090
    • Zhao M, Jiang B, Gao FH (2011) Small molecule inhibitors of STAT3 for cancer therapy. Curr Med Chem 18:4012–4018
    • (2011) Curr Med Chem , vol.18 , pp. 4012-4018
    • Zhao, M.1    Jiang, B.2    Gao, F.H.3
  • 35
    • 84958811619 scopus 로고    scopus 로고
    • Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation
    • COI: 1:CAS:528:DC%2BC28XivVGrs70%3D, PID: 26855338
    • Mi XG, Song ZB, Sun LG et al (2016) Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation. Int J Biochem Cell Biol 73:63–71
    • (2016) Int J Biochem Cell Biol , vol.73 , pp. 63-71
    • Mi, X.G.1    Song, Z.B.2    Sun, L.G.3
  • 36
    • 85009487706 scopus 로고    scopus 로고
    • Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo
    • PID: 26506421
    • Jia D, Tan Y, Liu H et al (2016) Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget 7:771–785
    • (2016) Oncotarget , vol.7 , pp. 771-785
    • Jia, D.1    Tan, Y.2    Liu, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.