Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells

Tumor Biology

Volumn 36, Issue 12, 2015, Pages 9667-9676

  Wu, Ning ^a   Liu, Jia ^b   Zhao, Xiangzhong ^c   Yan, Zhiyong ^c   Jiang, Bo ^a   Wang, Lijun ^a   Cao, Shousong ^d   Shi, Dayong ^a   Lin, Xiukun ^e  

^a INSTITUTE OF OCEANOLOGY   (China)

^b QINGDAO UNIVERSITY   (China)

^c Qingdao Medical University Affiliated Hospital   (China)

^d Inner Mongolia Shandong Gold Minerals Survey Co   (China)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cardamonin; Glioblastoma stem cell; Self renewal; STAT3; Temozolomide

Indexed keywords

ANTINEOPLASTIC AGENT; CARDAMONIN; CD133 ANTIGEN; CHALCONE DERIVATIVE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN; SURVIVIN; TEMOZOLOMIDE; UNCLASSIFIED DRUG; VASCULOTROPIN; STAT3 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DIMERIZATION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR GROWTH; ANIMAL; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; ENZYME ACTIVE SITE; GENETICS; MOLECULAR DOCKING; PATHOLOGY; PROTEIN CONFORMATION; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CHALCONES; DRUG RESISTANCE, NEOPLASM; GLIOBLASTOMA; HUMANS; MICE; MOLECULAR DOCKING SIMULATION; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84952874601     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3673-y     Document Type: Article

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